Kurt Giles, PhD

Title(s)Associate Director, HDF Comprehensive Cancer Ctr
SchoolSchool of Medicine
Address550 16th. Street, #6646
San Francisco CA 94158
Phone415-353-7390
ORCID ORCID Icon0000-0003-0796-4999 Additional info
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    Other Positions
    Title(s)Associate Director, UCSF Pancreas Center


    Collapse Research 
    Collapse Research Activities and Funding
    Degenerative and Dementing Diseases of Aging
    NIH P01AG002132Jan 1, 1981 - Mar 31, 2025
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model. Nat Commun. 2023 01 09; 14(1):118. Johnson NR, Yuan P, Castillo E, Lopez TP, Yue W, Bond A, Rivera BM, Sullivan MC, Hirouchi M, Giles K, Aoyagi A, Condello C. PMID: 36624100; PMCID: PMC9829908.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    2. Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta Neuropathol Commun. 2019 05 20; 7(1):81. Krejciova Z, Carlson GA, Giles K, Prusiner SB. PMID: 31109379; PMCID: PMC6526619.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. α-Synuclein: Multiple System Atrophy Prions. Cold Spring Harb Perspect Med. 2018 07 02; 8(7). Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB. PMID: 28213437; PMCID: PMC5561534.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    4. Modeling Multiple System Atrophy Prion Propagation in Astrocytes From Transgenic Mice. The FASEB Journal. 2018 Apr 1; 32:819.16-819.16. Krejciova KZ, Carlson CG, Giles GK, Prusiner PS. .
      View in: Publisher Site   Mentions:
    5. Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E782-E791. Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. PMID: 29311311; PMCID: PMC5789926.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    6. Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):E11029-E11036. Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. PMID: 29203673; PMCID: PMC5754811.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    7. A novel vector for transgenesis in the rat CNS. Acta Neuropathol Commun. 2017 Nov 21; 5(1):84. Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. PMID: 29157304; PMCID: PMC5697436.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Bioassays and Inactivation of Prions. Cold Spring Harb Perspect Biol. 2017 Aug 01; 9(8). Giles K, Woerman AL, Berry DB, Prusiner SB. PMID: 28246183; PMCID: PMC5538415.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    9. Developing Therapeutics for PrP Prion Diseases. Cold Spring Harb Perspect Med. 2017 Apr 03; 7(4). Giles K, Olson SH, Prusiner SB. PMID: 28096242; PMCID: PMC5378016.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    10. Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions. J Virol. 2016 11 01; 90(21):9558-9569. Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. PMID: 27440899; PMCID: PMC5068510.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    11. Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathol. 2016 10; 132(4):593-610. Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. PMID: 27350609; PMCID: PMC5152593.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    12. Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice. J Pharmacol Exp Ther. 2016 09; 358(3):537-47. Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. PMID: 27317802; PMCID: PMC4998675.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    13. Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):E5308-17. Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K. PMID: 26324905; PMCID: PMC4586853.
      View in: PubMed   Mentions: 357     Fields:    Translation:HumansAnimalsCells
    14. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Ann Neurol. 2015 Oct; 78(4):540-53. Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. PMID: 26094969; PMCID: PMC4711268.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    15. Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4949-58. Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. PMID: 26286986; PMCID: PMC4568231.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    16. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J Pharmacol Exp Ther. 2015 Oct; 355(1):2-12. Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. PMID: 26224882; PMCID: PMC4576665.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    17. Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice. J Infect Dis. 2015 Jul 15; 212 Suppl 1:S17-25. Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB. PMID: 26116725; PMCID: PMC4551108.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    18. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10323-8. Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. PMID: 24982139; PMCID: PMC4104857.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansAnimals
    19. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10329-34. Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. PMID: 24982137; PMCID: PMC4104853.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimals
    20. Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog. 2014 Apr; 10(4):e1003990. Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 24699458; PMCID: PMC3974871.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    21. Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells. Bioorg Med Chem. 2014 Mar 15; 22(6):1960-72. Silber BM, Gever JR, Rao S, Li Z, Renslo AR, Widjaja K, Wong C, Giles K, Freyman Y, Elepano M, Irwin JJ, Jacobson MP, Prusiner SB. PMID: 24530226; PMCID: PMC3984052.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    22. Transmission of multiple system atrophy prions to transgenic mice. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19555-60. Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. PMID: 24218576; PMCID: PMC3845125.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansAnimalsPHPublic Health
    23. Drug resistance confounding prion therapeutics. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):E4160-9. Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. PMID: 24128760; PMCID: PMC3816483.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    24. Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. J Pharmacol Exp Ther. 2013 Nov; 347(2):325-38. Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. PMID: 23965382; PMCID: PMC3807058.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCellsPHPublic Health
    25. Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharm Res. 2013 Apr; 30(4):932-50. Silber BM, Rao S, Fife KL, Gallardo-Godoy A, Renslo AR, Dalvie DK, Giles K, Freyman Y, Elepano M, Gever JR, Li Z, Jacobson MP, Huang Y, Benet LZ, Prusiner SB. PMID: 23417511; PMCID: PMC3640342.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    26. Chimeric elk/mouse prion proteins in transgenic mice. J Gen Virol. 2013 Feb; 94(Pt 2):443-452. Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. PMID: 23100369; PMCID: PMC3709613.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsPHPublic Health
    27. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. PLoS One. 2012; 7(7):e39112. Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. PMID: 22768295; PMCID: PMC3388068.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    28. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):11025-30. Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. PMID: 22711819; PMCID: PMC3390876.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimals
    29. Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol. 2012 Jun; 86(11):6033-41. Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. PMID: 22438549; PMCID: PMC3372217.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    30. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503. Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. PMID: 22331873; PMCID: PMC3295307.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    31. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Mol Ther Nucleic Acids. 2012 Feb 07; 1:e9. Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. PMID: 23344724; PMCID: PMC3381600.
      View in: PubMed   Mentions: 22  
    32. Salivary prions in sheep and deer. Prion. 2012 Jan-Mar; 6(1):52-61. Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB. PMID: 22453179; PMCID: PMC3338966.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    33. Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21223-8. Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. PMID: 22160704; PMCID: PMC3248514.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    34. Protease-resistant prions selectively decrease Shadoo protein. PLoS Pathog. 2011 Nov; 7(11):e1002382. Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. PMID: 22163178; PMCID: PMC3219722.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    35. Conserved properties of human and bovine prion strains on transmission to guinea pigs. Lab Invest. 2011 Sep; 91(9):1326-36. Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. PMID: 21727894; PMCID: PMC3164925.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    36. Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2528-33. Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. PMID: 21262831; PMCID: PMC3038719.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    37. Multiple effects of the cellular prion protein on tooth development. Int J Dev Biol. 2011; 55(10-12):953-60. Zhang Y, Kim SO, Opsahl-Vital S, Ho SP, Souron JB, Kim C, Giles K, Den Besten PK. PMID: 22252492.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    38. Human prion strain selection in transgenic mice. Ann Neurol. 2010 Aug; 68(2):151-61. Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. PMID: 20695008; PMCID: PMC2935907.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    39. How HIV-1 Rev Gets its Groove On. The FASEB Journal. 2010 Apr 1; 24:499.9-499.9. team tG, Colton CS, Herman HT, Giles GK, Koo KB, Jeske JS, Fernandes FJ, DeBella DS. .
      View in: Publisher Site   Mentions:
    40. Exploring Caspase Specificity with a Physical Three-Dimensional Model. The FASEB Journal. 2010 Apr 1; 24:487.3-487.3. team tG, Colton CS, Herman HT, Giles GK, Koo KB, Jeske JS, Crawford CE, DeBella DS. .
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    41. Design of a Three Dimensional Physical Model of P-glycoprotein. The FASEB Journal. 2010 Apr 1; 24:699.12-699.12. Team TL, Colton CS, Herman HT, Giles GK, Koo KB, Jeske JS, Grover GA, Gin GR. .
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    42. A tangible 3D model of the human Adipocyte Plasma Membrane-Associated Protein (APMAP). The FASEB Journal. 2010 Apr 1; 24:470.1-470.1. team tG, Colton CS, Herman HT, Giles GK, Koo KB, Jeske JS, Hicks HM, DeBella DS. .
      View in: Publisher Site   Mentions:
    43. Structural analysis of HIV-1 protease inhibition using physical models. The FASEB Journal. 2010 Apr 1; 24:837.5-837.5. Team TL, Colton CS, Herman HT, Giles GK, Koo KB, Jeske JS, Ollikainen ON, Reis RJ. .
      View in: Publisher Site   Mentions:
    44. Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS Pathog. 2009 Nov; 5(11):e1000673. Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. PMID: 19956709; PMCID: PMC2777304.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    45. Design and construction of diverse mammalian prion strains. Proc Natl Acad Sci U S A. 2009 Dec 01; 106(48):20417-22. Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB. PMID: 19915150; PMCID: PMC2787151.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    46. Measuring prions by bioluminescence imaging. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15002-6. Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19706444; PMCID: PMC2736416.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    47. The molecular basis for transmission of human prion strains. The FASEB Journal. 2009 Apr 1; 23:850.2-850.2. Giles GK, Patel PS, De Nicola DG, Korth KC, Lemus LA, DeArmond DS, Prusiner PS. .
      View in: Publisher Site   Mentions:
    48. Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein. J Gen Virol. 2009 Apr; 90(Pt 4):1035-1047. Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB. PMID: 19264659; PMCID: PMC2804060.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    49. Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. PLoS Pathog. 2008 Nov; 4(11):e1000206. Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB. PMID: 19008948; PMCID: PMC2576443.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    50. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10595-600. Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. PMID: 18647832; PMCID: PMC2492499.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    51. Genes contributing to prion pathogenesis. J Gen Virol. 2008 Jul; 89(Pt 7):1777-1788. Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB. PMID: 18559949; PMCID: PMC2828448.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimals
    52. Telling a molecular story: Tangible models of Cdc42 interacting with Intersectin. The FASEB Journal. 2008 Mar 1; 22:1045.1-1045.1. Team TL, Jeske JS, Chau CA, Giles GK, Colton CS, Reis RJ. .
      View in: Publisher Site   Mentions:
    53. Disinfection of Prions. New Biocides Development. 2007 Sep 7; 967:52-74. Giles GK, Supattapone SS, Peretz PD, Glidden GD, Baron BH, Prusiner PS. .
      View in: Publisher Site   Mentions:
    54. Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds. J Gen Virol. 2007 Apr; 88(Pt 4):1392-1401. Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BCH. PMID: 17374787.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    55. Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Mol Med. 2007 Mar-Apr; 13(3-4):190-8. Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. PMID: 17592554; PMCID: PMC1892763.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    56. Transgenic mouse brains for the evaluation and quality control of BSE tests. Biol Chem. 2007 Mar; 388(3):349-54. Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M, Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB. PMID: 17338644.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    57. Transmission of elk and deer prions to transgenic mice. J Virol. 2006 Sep; 80(18):9104-14. Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB. PMID: 16940522; PMCID: PMC1563923.
      View in: PubMed   Mentions: 101     Fields:    Translation:Animals
    58. Inactivation of prions by acidic sodium dodecyl sulfate. J Virol. 2006 Jan; 80(1):322-31. Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB. PMID: 16352557; PMCID: PMC1317507.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    59. Diagnosis of human prion disease. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3501-6. Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. PMID: 15741275; PMCID: PMC552933.
      View in: PubMed   Mentions: 114     Fields:    Translation:Humans
    60. Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II. Acta Crystallogr D Biol Crystallogr. 2000 Nov; 56(Pt 11):1385-94. Kryger G, Harel M, Giles K, Toker L, Velan B, Lazar A, Kronman C, Barak D, Ariel N, Shafferman A, Silman I, Sussman JL. PMID: 11053835.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    61. Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization. J Neurochem. 2000 May; 74(5):2146-53. Navaratnam DS, Fernando FS, Priddle JD, Giles K, Clegg SM, Pappin DJ, Craig I, Smith AD. PMID: 10800960.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    62. aCHEdb: the database system for ESTHER, the alpha/beta fold family of proteins and the Cholinesterase gene server. Nucleic Acids Res. 1998 Jan 01; 26(1):226-8. Cousin X, Hotelier T, Giles K, Toutant JP, Chatonnet A. PMID: 9399841; PMCID: PMC147245.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    63. Interactions underlying subunit association in cholinesterases. Protein Eng. 1997 Jun; 10(6):677-85. Giles K. PMID: 9278281.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    64. The alpha/beta fold family of proteins database and the cholinesterase gene server ESTHER. Nucleic Acids Res. 1997 Jan 01; 25(1):143-6. Cousin X, Hotelier T, Giles K, Lievin P, Toutant JP, Chatonnet A. PMID: 9016525; PMCID: PMC146416.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    65. Involvement of the NMDA receptor in a non-cholinergic action of acetylcholinesterase in guinea-pig substantia nigra pars compacta neurons. Eur J Neurosci. 1996 Apr; 8(4):837-41. Webb CP, Nedergaard S, Giles K, Greenfield SA. PMID: 9081636.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
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