Stephen De Armond, MD, PhD

Title(s)Professor Emeritus, Pathology
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #450E
San Francisco CA 94143
Phone415-502-6603
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    Collapse Research 
    Collapse Research Activities and Funding
    New Approaches to Dementia Heterogeneity
    NIH P50AG023501Apr 1, 2004 - Mar 31, 2019
    Role: Co-Investigator
    Novel Therapeutics for Prion Diseases
    NIH P01AG021601Jun 1, 2003 - Feb 28, 2015
    Role: Co-Investigator
    Genetics of Prion Susceptibility in vitro
    NIH P01NS041997Sep 30, 2001 - Jun 30, 2013
    Role: Co-Investigator
    Molecular Pathogenesis of Age-Dependent CNS Regeneration
    NIH P01AG010770Apr 1, 1993 - Mar 31, 2016
    Role: Co-Principal Investigator
    TRANSMISSIBLE AND GENETIC NEURODENGENERATIVE DISEASES
    NIH P01NS022786Sep 1, 1985 - Jun 30, 2000
    Role: Co-Investigator
    Degenerative and Dementing Diseases of Aging
    NIH P01AG002132Jan 1, 1981 - Mar 31, 2025
    Role: Co-Investigator
    CNS DEGENERATION CAUSED BY NOVEL PATHOGENS
    NIH P50NS014069Nov 30, 2002
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Default Mode Network quantitative diffusion and resting-state functional magnetic resonance imaging correlates in sporadic Creutzfeldt-Jakob disease. Hum Brain Mapp. 2022 09; 43(13):4158-4173. Paoletti M, Caverzasi E, Mandelli ML, Brown JA, Henry RG, Miller BL, Rosen HJ, DeArmond SJ, Bastianello S, Seeley WW, Geschwind MD. PMID: 35662331; PMCID: PMC9374887.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration. Neurology. 2018 03 20; 90(12):e1047-e1056. Seo SW, Thibodeau MP, Perry DC, Hua A, Sidhu M, Sible I, Vargas JNS, Gaus SE, Rabinovici GD, Rankin KD, Boxer AL, Kramer JH, Rosen HJ, Gorno-Tempini ML, Grinberg LT, Huang EJ, DeArmond SJ, Trojanowski JQ, Miller BL, Seeley WW. PMID: 29453245; PMCID: PMC5874448.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    3. Autobiography Series: From Sleep-Wake Mechanisms to Prion Diseases. J Neuropathol Exp Neurol. 2017 07 01; 76(7):631-642. DeArmond SJ. PMID: 28863454.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2016 Mar; 75(3):256-62. Ahn M, Kalume F, Pitstick R, Oehler A, Carlson G, DeArmond SJ. PMID: 26851378; PMCID: PMC4902861.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. Selective Frontoinsular von Economo Neuron and Fork Cell Loss in Early Behavioral Variant Frontotemporal Dementia. Cereb Cortex. 2016 Apr; 26(4):1843. Kim EJ, Sidhu M, Gaus SE, Huang EJ, Hof PR, Miller BL, DeArmond SJ, Seeley WW. PMID: 26796215; PMCID: PMC6272814.
      View in: PubMed   Mentions: 4     Fields:    
    6. Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes. J Neuropathol Exp Neurol. 2015 Sep; 74(9):873-88. Tousseyn T, Bajsarowicz K, Sánchez H, Gheyara A, Oehler A, Geschwind M, DeArmond B, DeArmond SJ. PMID: 26226132; PMCID: PMC5094352.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    7. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Ann Neurol. 2015 Oct; 78(4):540-53. Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. PMID: 26094969; PMCID: PMC4711268.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    8. Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J Pharmacol Exp Ther. 2015 Oct; 355(1):2-12. Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. PMID: 26224882; PMCID: PMC4576665.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    9. Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice. J Infect Dis. 2015 Jul 15; 212 Suppl 1:S17-25. Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB. PMID: 26116725; PMCID: PMC4551108.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    10. Metabolic disorders with clinical and radiologic features of sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Apr; 5(2):108-115. Rosenbloom MH, Tartaglia MC, Forner SA, Wong KK, Kuo A, Johnson DY, Colacurcio V, Andrews BD, Miller BL, DeArmond SJ, Geschwind MD. PMID: 26137419; PMCID: PMC4404281.
      View in: PubMed   Mentions: 5  
    11. White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54. Caverzasi E, Mandelli ML, DeArmond SJ, Hess CP, Vitali P, Papinutto N, Oehler A, Miller BL, Lobach IV, Bastianello S, Geschwind MD, Henry RG. PMID: 25367029; PMCID: PMC4240303.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    12. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10329-34. Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. PMID: 24982137; PMCID: PMC4104853.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimals
    13. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10323-8. Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. PMID: 24982139; PMCID: PMC4104857.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansAnimals
    14. Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice. PLoS One. 2014; 9(5):e98496. Ahn M, Bajsarowicz K, Oehler A, Lemus A, Bankiewicz K, DeArmond SJ. PMID: 24866748; PMCID: PMC4035323.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    15. Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog. 2014 Apr; 10(4):e1003990. Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 24699458; PMCID: PMC3974871.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    16. Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases. Acta Neuropathol Commun. 2013 Dec 12; 1:80. Kim MO, Cali I, Oehler A, Fong JC, Wong K, See T, Katz JS, Gambetti P, Bettcher BM, Dearmond SJ, Geschwind MD. PMID: 24330864; PMCID: PMC3880091.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    17. AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol Ther. 2014 Feb; 22(2):329-337. Samaranch L, Sebastian WS, Kells AP, Salegio EA, Heller G, Bringas JR, Pivirotto P, DeArmond S, Forsayeth J, Bankiewicz KS. PMID: 24419081; PMCID: PMC3918916.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    18. Transmission of multiple system atrophy prions to transgenic mice. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19555-60. Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. PMID: 24218576; PMCID: PMC3845125.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansAnimalsPHPublic Health
    19. Drug resistance confounding prion therapeutics. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):E4160-9. Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. PMID: 24128760; PMCID: PMC3816483.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    20. Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease. Neurology. 2013 Dec 03; 81(23):2015-23. Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner SB, Miller BL. PMID: 24122181; PMCID: PMC4211922.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    21. Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. J Pharmacol Exp Ther. 2013 Nov; 347(2):325-38. Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. PMID: 23965382; PMCID: PMC3807058.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCellsPHPublic Health
    22. Convergent replication of mouse synthetic prion strains. Am J Pathol. 2013 Mar; 182(3):866-74. Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 23438476; PMCID: PMC3586687.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    23. Sporadic Jakob-Creutzfeldt disease presenting as primary progressive aphasia. JAMA Neurol. 2013 Feb; 70(2):254-7. Johnson DY, Dunkelberger DL, Henry M, Haman A, Greicius MD, Wong K, DeArmond SJ, Miller BL, Gorno-Tempini ML, Geschwind MD. PMID: 23400721; PMCID: PMC4365870.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease. PLoS One. 2013; 8(1):e55575. Silvius D, Pitstick R, Ahn M, Meishery D, Oehler A, Barsh GS, DeArmond SJ, Carlson GA, Gunn TM. PMID: 23383230; PMCID: PMC3559536.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. Patterns of striatal degeneration in frontotemporal dementia. Alzheimer Dis Assoc Disord. 2013 Jan-Mar; 27(1):74-83. Halabi C, Halabi A, Dean DL, Wang PN, Boxer AL, Trojanowski JQ, Dearmond SJ, Miller BL, Kramer JH, Seeley WW. PMID: 22367382; PMCID: PMC3389579.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    26. Differential diagnosis of Jakob-Creutzfeldt disease. Arch Neurol. 2012 Dec; 69(12):1578-82. Paterson RW, Torres-Chae CC, Kuo AL, Ando T, Nguyen EA, Wong K, DeArmond SJ, Haman A, Garcia P, Johnson DY, Miller BL, Geschwind MD. PMID: 23229042; PMCID: PMC4401069.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    27. Chimeric elk/mouse prion proteins in transgenic mice. J Gen Virol. 2013 Feb; 94(Pt 2):443-452. Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. PMID: 23100369; PMCID: PMC3709613.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsPHPublic Health
    28. Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. PLoS One. 2012; 7(7):e39112. Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. PMID: 22768295; PMCID: PMC3388068.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    29. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):11025-30. Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. PMID: 22711819; PMCID: PMC3390876.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimals
    30. A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases. J Neuropathol Exp Neurol. 2012 May; 71(5):449-66. Bajsarowicz K, Ahn M, Ackerman L, Dearmond BN, Carlson G, DeArmond SJ. PMID: 22507918.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    31. Clinical overlap between Jakob-Creutzfeldt disease and Lewy body disease. Can J Neurol Sci. 2012 May; 39(3):304-10. Tartaglia MC, Johnson DY, Thai JN, Cattaruzza T, Wong K, Garcia P, Dearmond SJ, Miller BL, Geschwind MD. PMID: 22547509; PMCID: PMC3590309.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol. 2012 Jun; 86(11):6033-41. Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. PMID: 22438549; PMCID: PMC3372217.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    33. Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503. Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. PMID: 22331873; PMCID: PMC3295307.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    34. Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Mol Ther Nucleic Acids. 2012 Feb 07; 1:e9. Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. PMID: 23344724; PMCID: PMC3381600.
      View in: PubMed   Mentions: 22  
    35. Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum. Hum Gene Ther. 2012 Feb; 23(2):210-7. San Sebastian W, Richardson RM, Kells AP, Lamarre C, Bringas J, Pivirotto P, Salegio EA, Dearmond SJ, Forsayeth J, Bankiewicz KS. PMID: 22017504; PMCID: PMC3277736.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    36. Salivary prions in sheep and deer. Prion. 2012 Jan-Mar; 6(1):52-61. Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB. PMID: 22453179; PMCID: PMC3338966.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    37. Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21223-8. Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. PMID: 22160704; PMCID: PMC3248514.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    38. Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation. PLoS Pathog. 2011 Nov; 7(11):e1002391. Westaway D, Genovesi S, Daude N, Brown R, Lau A, Lee I, Mays CE, Coomaraswamy J, Canine B, Pitstick R, Herbst A, Yang J, Ko KW, Schmitt-Ulms G, Dearmond SJ, McKenzie D, Hood L, Carlson GA. PMID: 22114562; PMCID: PMC3219720.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    39. Protease-resistant prions selectively decrease Shadoo protein. PLoS Pathog. 2011 Nov; 7(11):e1002382. Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. PMID: 22163178; PMCID: PMC3219722.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    40. Behavioral variant frontotemporal dementia with corticobasal degeneration pathology: phenotypic comparison to bvFTD with Pick's disease. J Mol Neurosci. 2011 Nov; 45(3):594-608. Rankin KP, Mayo MC, Seeley WW, Lee S, Rabinovici G, Gorno-Tempini ML, Boxer AL, Weiner MW, Trojanowski JQ, DeArmond SJ, Miller BL. PMID: 21881831; PMCID: PMC3208125.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    41. Conformational transformation and selection of synthetic prion strains. J Mol Biol. 2011 Oct 28; 413(3):527-42. Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. PMID: 21839745; PMCID: PMC3195964.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    42. Clinicopathological correlations in corticobasal degeneration. Ann Neurol. 2011 Aug; 70(2):327-40. Lee SE, Rabinovici GD, Mayo MC, Wilson SM, Seeley WW, DeArmond SJ, Huang EJ, Trojanowski JQ, Growdon ME, Jang JY, Sidhu M, See TM, Karydas AM, Gorno-Tempini ML, Boxer AL, Weiner MW, Geschwind MD, Rankin KP, Miller BL. PMID: 21823158; PMCID: PMC3154081.
      View in: PubMed   Mentions: 186     Fields:    Translation:Humans
    43. Conserved properties of human and bovine prion strains on transmission to guinea pigs. Lab Invest. 2011 Sep; 91(9):1326-36. Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. PMID: 21727894; PMCID: PMC3164925.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    44. Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia. Cereb Cortex. 2012 Feb; 22(2):251-9. Kim EJ, Sidhu M, Gaus SE, Huang EJ, Hof PR, Miller BL, DeArmond SJ, Seeley WW. PMID: 21653702; PMCID: PMC3256403.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    45. Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2528-33. Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. PMID: 21262831; PMCID: PMC3038719.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    46. Pathologic evidence that the T188R mutation in PRNP is associated with prion disease. J Neuropathol Exp Neurol. 2010 Dec; 69(12):1220-7. Tartaglia MC, Thai JN, See T, Kuo A, Harbaugh R, Raudabaugh B, Cali I, Sattavat M, Sanchez H, DeArmond SJ, Geschwind MD. PMID: 21107135; PMCID: PMC3136530.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. PMID: 20695009; PMCID: PMC3032610.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    48. Human prion strain selection in transgenic mice. Ann Neurol. 2010 Aug; 68(2):151-61. Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. PMID: 20695008; PMCID: PMC2935907.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    49. Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry. 2011 Feb; 82(2):196-203. Boxer AL, Mackenzie IR, Boeve BF, Baker M, Seeley WW, Crook R, Feldman H, Hsiung GY, Rutherford N, Laluz V, Whitwell J, Foti D, McDade E, Molano J, Karydas A, Wojtas A, Goldman J, Mirsky J, Sengdy P, Dearmond S, Miller BL, Rademakers R. PMID: 20562461; PMCID: PMC3017222.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    50. Conformation-dependent high-affinity monoclonal antibodies to prion proteins. J Immunol. 2010 Jul 01; 185(1):729-37. Stanker LH, Serban AV, Cleveland E, Hnasko R, Lemus A, Safar J, DeArmond SJ, Prusiner SB. PMID: 20530267; PMCID: PMC2957185.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    51. Protease-sensitive synthetic prions. PLoS Pathog. 2010 Jan 22; 6(1):e1000736. Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, Lemus A, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 20107515; PMCID: PMC2809756.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    52. PrPSc accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases. Mol Neurodegener. 2010 Jan 21; 5:6. Dearmond SJ, Bajsarowicz K. PMID: 20205843; PMCID: PMC2825502.
      View in: PubMed   Mentions: 10     Fields:    
    53. Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS Pathog. 2009 Nov; 5(11):e1000673. Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. PMID: 19956709; PMCID: PMC2777304.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    54. Design and construction of diverse mammalian prion strains. Proc Natl Acad Sci U S A. 2009 Dec 01; 106(48):20417-22. Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB. PMID: 19915150; PMCID: PMC2787151.
      View in: PubMed   Mentions: 129     Fields:    Translation:AnimalsCells
    55. Sporadic corticobasal syndrome due to FTLD-TDP. Acta Neuropathol. 2010 Mar; 119(3):365-74. Tartaglia MC, Sidhu M, Laluz V, Racine C, Rabinovici GD, Creighton K, Karydas A, Rademakers R, Huang EJ, Miller BL, DeArmond SJ, Seeley WW. PMID: 19876635; PMCID: PMC2832091.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    56. The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases. Database (Oxford). 2009; 2009:bap011. Gehlenborg N, Hwang D, Lee IY, Yoo H, Baxter D, Petritis B, Pitstick R, Marzolf B, Dearmond SJ, Carlson GA, Hood L. PMID: 20157484; PMCID: PMC2790306.
      View in: PubMed   Mentions: 14     Fields:    
    57. Asymptomatic deer excrete infectious prions in faeces. Nature. 2009 Sep 24; 461(7263):529-32. Tamgüney G, Miller MW, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19741608; PMCID: PMC3186440.
      View in: PubMed   Mentions: 122     Fields:    Translation:Animals
    58. Measuring prions by bioluminescence imaging. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15002-6. Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19706444; PMCID: PMC2736416.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    59. A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP. J Neurosci. 2009 Aug 12; 29(32):10072-80. Yang W, Cook J, Rassbach B, Lemus A, DeArmond SJ, Mastrianni JA. PMID: 19675240; PMCID: PMC2749997.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    60. Seizures in corticobasal degeneration: a case report. Neurocase. 2009 Aug; 15(4):352-6. Douglas VC, DeArmond SJ, Aminoff MJ, Miller BL, Rabinovici GD. PMID: 19544144; PMCID: PMC2829102.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    61. A systems approach to prion disease. Mol Syst Biol. 2009; 5:252. Hwang D, Lee IY, Yoo H, Gehlenborg N, Cho JH, Petritis B, Baxter D, Pitstick R, Young R, Spicer D, Price ND, Hohmann JG, Dearmond SJ, Carlson GA, Hood LE. PMID: 19308092; PMCID: PMC2671916.
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    62. Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein. J Gen Virol. 2009 Apr; 90(Pt 4):1035-1047. Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB. PMID: 19264659; PMCID: PMC2804060.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    63. Correlating DWI MRI with pathologic and other features of Jakob-Creutzfeldt disease. Alzheimer Dis Assoc Disord. 2009 Jan-Mar; 23(1):82-87. Geschwind MD, Potter CA, Sattavat M, Garcia PA, Rosen HJ, Miller BL, DeArmond SJ. PMID: 19266702; PMCID: PMC2684989.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    64. Cryo-immunogold electron microscopy for prions: toward identification of a conversion site. J Neurosci. 2008 Nov 19; 28(47):12489-99. Godsave SF, Wille H, Kujala P, Latawiec D, DeArmond SJ, Serban A, Prusiner SB, Peters PJ. PMID: 19020041; PMCID: PMC2796247.
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    65. Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. PLoS Pathog. 2008 Nov; 4(11):e1000206. Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB. PMID: 19008948; PMCID: PMC2576443.
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    66. A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10595-600. Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. PMID: 18647832; PMCID: PMC2492499.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    67. Transmission and detection of prions in feces. J Infect Dis. 2008 Jul 01; 198(1):81-9. Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, Dearmond SJ, Prusiner SB. PMID: 18505383; PMCID: PMC2803675.
      View in: PubMed   Mentions: 76     Fields:    Translation:Animals
    68. Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S50-7. Seeley WW, Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, Dearmond SJ, Miller BL. PMID: 18090425.
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    69. Developmental expression of PrP in the post-implantation embryo. Brain Res. 2007 Mar 30; 1139:60-7. Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ. PMID: 17292334; PMCID: PMC2706582.
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    70. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):19105-10. Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 17142317; PMCID: PMC1748184.
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    71. Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol. 2006 Dec; 60(6):660-7. Seeley WW, Carlin DA, Allman JM, Macedo MN, Bush C, Miller BL, Dearmond SJ. PMID: 17187353.
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    72. Transmission of elk and deer prions to transgenic mice. J Virol. 2006 Sep; 80(18):9104-14. Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB. PMID: 16940522; PMCID: PMC1563923.
      View in: PubMed   Mentions: 101     Fields:    Translation:Animals
    73. Human prions and plasma lipoproteins. Proc Natl Acad Sci U S A. 2006 Jul 25; 103(30):11312-7. Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB. PMID: 16849426; PMCID: PMC1544083.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    74. Changes in neuropeptide expression in mice infected with prions. Neurobiol Aging. 2007 May; 28(5):748-65. Diez M, Groth D, DeArmond SJ, Prusiner SB, Hökfelt T. PMID: 16621165.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    75. Prion infection of mouse neurospheres. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3875-80. Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson GA. PMID: 16495413; PMCID: PMC1533787.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    76. Human growth hormone-related iatrogenic Creutzfeldt-Jakob disease with abnormal imaging. Arch Neurol. 2006 Feb; 63(2):288-90. Lewis AM, Yu M, DeArmond SJ, Dillon WP, Miller BL, Geschwind MD. PMID: 16476821.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    77. Inactivation of prions by acidic sodium dodecyl sulfate. J Virol. 2006 Jan; 80(1):322-31. Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB. PMID: 16352557; PMCID: PMC1317507.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    78. Prion clearance in bigenic mice. J Gen Virol. 2005 Oct; 86(Pt 10):2913-2923. Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P. PMID: 16186247.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    79. Transmission barriers for bovine, ovine, and human prions in transgenic mice. J Virol. 2005 May; 79(9):5259-71. Scott MR, Peretz D, Nguyen HO, Dearmond SJ, Prusiner SB. PMID: 15827140; PMCID: PMC1082721.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    80. Infant botulism, type F, presenting at 54 hours of life. Pediatr Neurol. 2005 Mar; 32(3):193-6. Keet CA, Fox CK, Margeta M, Marco E, Shane AL, Dearmond SJ, Strober JB, Miller SP. PMID: 15730901.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    81. Diagnosis of human prion disease. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3501-6. Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. PMID: 15741275; PMCID: PMC552933.
      View in: PubMed   Mentions: 114     Fields:    Translation:Humans
    82. Prion-associated dilated cardiomyopathy. Arch Intern Med. 2005 Feb 14; 165(3):338-40. Ashwath ML, Dearmond SJ, Culclasure T. PMID: 15710800.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    83. Strain-specified characteristics of mouse synthetic prions. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2168-73. Legname G, Nguyen HO, Baskakov IV, Cohen FE, Dearmond SJ, Prusiner SB. PMID: 15671162; PMCID: PMC548557.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    84. Notch-1 activation and dendritic atrophy in prion disease. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):886-91. Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ. PMID: 15640354; PMCID: PMC545568.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    85. Discovering the mechanisms of neurodegeneration in prion diseases. Neurochem Res. 2004 Nov; 29(11):1979-98. DeArmond SJ. PMID: 15662833.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    86. Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2004 Nov; 35(11):2518-22. Smith WS, Dowd CF, Johnston SC, Ko NU, DeArmond SJ, Dillon WP, Setty D, Lawton MT, Young WL, Higashida RT, Halbach VV. PMID: 15472097.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    87. The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system. J Neuropathol Exp Neurol. 2004 Aug; 63(8):882-99. Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ, DeArmond SJ. PMID: 15330342.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    88. Synthetic mammalian prions. Science. 2004 Jul 30; 305(5684):673-6. Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 15286374.
      View in: PubMed   Mentions: 403     Fields:    Translation:AnimalsCells
    89. Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nat Biotechnol. 2004 Jun; 22(6):724-31. Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. PMID: 15146195.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    90. Mutant PrPSc conformers induced by a synthetic peptide and several prion strains. J Virol. 2004 Feb; 78(4):2088-99. Tremblay P, Ball HL, Kaneko K, Groth D, Hegde RS, Cohen FE, DeArmond SJ, Prusiner SB, Safar JG. PMID: 14747574; PMCID: PMC369494.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    91. Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol. 2003 Aug 18; 162(4):703-17. Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB. PMID: 12925711; PMCID: PMC2173792.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    92. Cytosolic prion protein in neurons. J Neurosci. 2003 Aug 06; 23(18):7183-93. Mironov A, Latawiec D, Wille H, Bouzamondo-Bernstein E, Legname G, Williamson RA, Burton D, DeArmond SJ, Prusiner SB, Peters PJ. PMID: 12904479; PMCID: PMC6740654.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    93. Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease. Arch Neurol. 2003 Jun; 60(6):813-6. Geschwind MD, Martindale J, Miller D, DeArmond SJ, Uyehara-Lock J, Gaskin D, Kramer JH, Barbaro NM, Miller BL. PMID: 12810484.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    94. Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4784-9. Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. PMID: 12684540; PMCID: PMC153633.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    95. Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. Clin Lab Med. 2003 Mar; 23(1):1-41. DeArmond SJ, Prusiner SB. PMID: 12733423.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    96. T cells infiltrate the brain in murine and human transmissible spongiform encephalopathies. J Virol. 2003 Mar; 77(6):3799-808. Lewicki H, Tishon A, Homann D, Mazarguil H, Laval F, Asensio VC, Campbell IL, DeArmond S, Coon B, Teng C, Gairin JE, Oldstone MB. PMID: 12610154; PMCID: PMC149501.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    97. Fundamentals of prion biology and diseases. Toxicology. 2002 Dec 27; 181-182:9-16. DeArmond SJ, Bouzamondo E. PMID: 12505278.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    98. A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron. 2002 Jun 13; 34(6):921-32. Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR. PMID: 12086640.
      View in: PubMed   Mentions: 118     Fields:    Translation:HumansAnimalsCells
    99. Prions in skeletal muscle. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3812-7. Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. PMID: 11904434; PMCID: PMC122606.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCellsPHPublic Health
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