Abby Oehler

Title(s)	Staff Research Associate III, Institute for Neurodegenerative Diseases
School	School of Medicine
Address	675 Nelson Rising Lane, #302 San Francisco CA 94158
Phone	415-502-7072
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP. bioRxiv. 2023 Aug 16. Nadel CM, Wucherer K, Oehler A, Thwin AC, Basu K, Callahan MD, Southworth DR, Mordes DA, Craik CS, Gestwicki JE. PMID: 37645969; PMCID: PMC10462110.

View in: PubMed Mentions:
Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. PLoS Pathog. 2020 02; 16(2):e1008222. Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. PMID: 32017806; PMCID: PMC6999861.

View in: PubMed Mentions: 15 Fields:
Mic Microbiology
Translation:Humans Animals
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines. Acta Neuropathol. 2019 03; 137(3):437-454. Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. PMID: 30690664; PMCID: PMC6454887.

View in: PubMed Mentions: 47 Fields:
Neu Neurology
Translation:Humans Animals
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E782-E791. Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. PMID: 29311311; PMCID: PMC5789926.

View in: PubMed Mentions: 62 Fields:
Sci Science
Translation:Animals Cells
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):409-414. Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. PMID: 29279394; PMCID: PMC5777081.

View in: PubMed Mentions: 22 Fields:
Sci Science
Translation:Humans Animals Cells
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):E11029-E11036. Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. PMID: 29203673; PMCID: PMC5754811.

View in: PubMed Mentions: 12 Fields:
Sci Science
Translation:Humans Animals Cells
Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. JAMA Neurol. 2017 12 01; 74(12):1464-1472. Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. PMID: 29059326; PMCID: PMC5822201.

View in: PubMed Mentions: 25 Fields:
Neu Neurology
Translation:Humans Animals
A novel vector for transgenesis in the rat CNS. Acta Neuropathol Commun. 2017 Nov 21; 5(1):84. Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. PMID: 29157304; PMCID: PMC5697436.

View in: PubMed Mentions: Fields:
Neu Neurology
Translation:Animals Cells
Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions. J Virol. 2016 11 01; 90(21):9558-9569. Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. PMID: 27440899; PMCID: PMC5068510.

View in: PubMed Mentions: 3 Fields:
Vir Virology
Translation:Humans Animals
Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathol. 2016 10; 132(4):593-610. Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. PMID: 27350609; PMCID: PMC5152593.

View in: PubMed Mentions: 26 Fields:
Neu Neurology
Translation:Animals
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice. J Pharmacol Exp Ther. 2016 09; 358(3):537-47. Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. PMID: 27317802; PMCID: PMC4998675.

View in: PubMed Mentions: 15 Fields:
Dru Drug Therapy Pha Pharmacology
Translation:Animals
Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2016 Mar; 75(3):256-62. Ahn M, Kalume F, Pitstick R, Oehler A, Carlson G, DeArmond SJ. PMID: 26851378; PMCID: PMC4902861.

View in: PubMed Mentions: 5 Fields:
Neu Neurology Pat Pathology
Translation:Humans Animals Cells
Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes. J Neuropathol Exp Neurol. 2015 Sep; 74(9):873-88. Tousseyn T, Bajsarowicz K, Sánchez H, Gheyara A, Oehler A, Geschwind M, DeArmond B, DeArmond SJ. PMID: 26226132; PMCID: PMC5094352.

View in: PubMed Mentions: 20 Fields:
Neu Neurology Pat Pathology
Translation:Humans Animals
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):E5308-17. Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K. PMID: 26324905; PMCID: PMC4586853.

View in: PubMed Mentions: 357 Fields:
Sci Science
Translation:Humans Animals Cells
Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4949-58. Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. PMID: 26286986; PMCID: PMC4568231.

View in: PubMed Mentions: 125 Fields:
Sci Science
Translation:Humans Animals Cells
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J Pharmacol Exp Ther. 2015 Oct; 355(1):2-12. Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. PMID: 26224882; PMCID: PMC4576665.

View in: PubMed Mentions: 26 Fields:
Dru Drug Therapy Pha Pharmacology
Translation:Humans Animals
White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54. Caverzasi E, Mandelli ML, DeArmond SJ, Hess CP, Vitali P, Papinutto N, Oehler A, Miller BL, Lobach IV, Bastianello S, Geschwind MD, Henry RG. PMID: 25367029; PMCID: PMC4240303.

View in: PubMed Mentions: 18 Fields:
Bra Brain Neu Neurology
Translation:Humans Cells
Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice. PLoS One. 2014; 9(5):e98496. Ahn M, Bajsarowicz K, Oehler A, Lemus A, Bankiewicz K, DeArmond SJ. PMID: 24866748; PMCID: PMC4035323.

View in: PubMed Mentions: 7 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog. 2014 Apr; 10(4):e1003990. Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 24699458; PMCID: PMC3974871.

View in: PubMed Mentions: 65 Fields:
Mic Microbiology
Translation:Humans Animals
Transmission of multiple system atrophy prions to transgenic mice. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19555-60. Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. PMID: 24218576; PMCID: PMC3845125.

View in: PubMed Mentions: 220 Fields:
Sci Science
Translation:Humans Animals PHPublic Health
Drug resistance confounding prion therapeutics. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):E4160-9. Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. PMID: 24128760; PMCID: PMC3816483.

View in: PubMed Mentions: 68 Fields:
Sci Science
Translation:Humans Animals Cells
Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. J Pharmacol Exp Ther. 2013 Nov; 347(2):325-38. Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. PMID: 23965382; PMCID: PMC3807058.

View in: PubMed Mentions: 23 Fields:
Dru Drug Therapy Pha Pharmacology
Translation:Animals Cells PHPublic Health
Convergent replication of mouse synthetic prion strains. Am J Pathol. 2013 Mar; 182(3):866-74. Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 23438476; PMCID: PMC3586687.

View in: PubMed Mentions: 22 Fields:
Pat Pathology
Translation:Animals Cells
Chimeric elk/mouse prion proteins in transgenic mice. J Gen Virol. 2013 Feb; 94(Pt 2):443-452. Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. PMID: 23100369; PMCID: PMC3709613.

View in: PubMed Mentions: 8 Fields:
Vir Virology
Translation:Animals PHPublic Health
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):11025-30. Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. PMID: 22711819; PMCID: PMC3390876.

View in: PubMed Mentions: 192 Fields:
Sci Science
Translation:Humans Animals
Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol. 2012 Jun; 86(11):6033-41. Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. PMID: 22438549; PMCID: PMC3372217.

View in: PubMed Mentions: 11 Fields:
Vir Virology
Translation:Humans Animals PHPublic Health
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503. Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. PMID: 22331873; PMCID: PMC3295307.

View in: PubMed Mentions: 42 Fields:
Sci Science
Translation:Animals Cells
Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21223-8. Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. PMID: 22160704; PMCID: PMC3248514.

View in: PubMed Mentions: 46 Fields:
Sci Science
Translation:Animals Cells
Protease-resistant prions selectively decrease Shadoo protein. PLoS Pathog. 2011 Nov; 7(11):e1002382. Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. PMID: 22163178; PMCID: PMC3219722.

View in: PubMed Mentions: 26 Fields:
Mic Microbiology
Translation:Animals Cells