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Danilo Bernardo, JR, MD

Photo of Danilo Bernardo, JR, MD
Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address550 16th Street, #5230
San Francisco CA 94158
Phone310-825-6681
PronounsHe/Him/His
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse education and training
    UCLA, Los Angeles2019Pediatric Epilepsy
    UCLA, Los Angeles2018Clinical Neurophysiology
    UCLA, Los Angeles2017Child Neurology
    University of North Carolina2014Neurology
    University of North Carolina2010MD

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    Dr. Bernardo is a pediatric neurologist and epileptologist in the Department of Neurology at UCSF. He has clinical interests in the treatment of early childhood-onset epilepsy, drug resistant epilepsy, and in surgical treatments for drug resistant epilepsy. His research involves the development of computational approaches to guide the diagnosis and treatment of childhood forms of epilepsy.
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Knowledge graph representation of the mappings between seizure semiology and epileptogenic zones. Sci Rep. 2026 Jan 10. Yang S, Wen Z, Zhan W, Fotedar N, Shih YC, Ding JE, Bernardo D, Kallioniemi E, Weil AG, Huang X, Rosenow F, Sun H, Liu YT, Wu S, Liu F. PMID: 41519982.
      View in: PubMed   Mentions:
    2. Automated EEG Background Analysis and 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. JAMA Netw Open. 2025 Dec 01; 8(12):e2548321. Cornet MC, Numis AL, Wusthoff CJ, Bernardo D, Mietzsch U, Thomas C, Natarajan N, Ahmad KA, Scheffler A, Juul SE, Montazeri Moghadam S, Wu YW, Glass HC. PMID: 41400952; PMCID: PMC12709380.
      View in: PubMed   Mentions:
    3. Limitations of large language models in clinical problem-solving arising from inflexible reasoning. Sci Rep. 2025 Nov 11; 15(1):39426. Kim J, Podlasek A, Shidara K, Liu F, Alaa A, Bernardo D. PMID: 41219270; PMCID: PMC12606185.
      View in: PubMed   Mentions:
    4. Factors Associated With More Medication Trials Before Surgical Evaluation and Postsurgical Outcomes in Pediatric Drug-Resistant Epilepsy. Neurology. 2025 Nov 11; 105(9):e214198. Samanta D, Newell G, Caraway AR, Brock E, Albert GW, Novotny EJ, Depositario Cabacar DF, Oluigbo CO, Gaillard WD, Tatachar P, Bolton JB, Wong-Kisiel L, Romanowski EF, Mcnamara NA, Eschbach K, Alexander AL, Auguste KI, Gonzalez-Giraldo E, Bernardo D, Ostendorf AP, Coryell J, Karia S, Karakas C, Javarayee PK, Pichon PD, Olaya J, Shrey DW, Reddy SB, Ganesh A, Hauptman JS, Singh RK, Ciliberto M, Marashly A, Grinspan ZM, Nangia S, Arredondo K, Miller DJ, Sattar S, Montenegro M, Agarwal N, Galan FN, Wagner J, Abel TJ, Knox AT, Perry MS. PMID: 41056528.
      View in: PubMed   Mentions:
    5. Outcomes of Early-Life Focal Cortical Dysplasia-Related Epilepsy: A PERC Surgery Study. Neurol Clin Pract. 2025 Dec; 15(6):e200539. Cohen NT, Depositario-Cabacar DF, Oluigbo CO, Ostendorf AP, Wong-Kisiel L, Fedak Romanowski E, McNamara NA, Tatachar P, Eschbach K, Alexander AL, Pichon PD, Ciliberto MA, Gonzalez-Giraldo E, Bernardo D, Auguste KI, Coryell J, Arredondo KH, Novotny EJ, Reddy SB, Ganesh A, Marashly A, Javarayee PK, Singh RK, Bolton JB, Grinspan ZM, Karia S, Karakas C, Lin J, Knox AT, Wolf SM, Abel TJ, Samanta D, Armstrong DM, Pavuluri S, Hyslop A, Galan FN, Miller DJ, Hauptman JS, Caraway AR, Perry MS, Gaillard WD. PMID: 41070137; PMCID: PMC12507445.
      View in: PubMed   Mentions:
    6. Short-horizon neonatal seizure prediction using EEG-based deep learning. PLOS Digit Health. 2025 Jul; 4(7):e0000890. Kim J, Amorim E, Rao VR, Glass HC, Bernardo D. PMID: 40644380; PMCID: PMC12250315.
      View in: PubMed   Mentions:
    7. Payer type and prediction of the time from epilepsy onset to neurosurgical intervention and from first diagnostic MRI to neurosurgical consultation in lesional drug-resistant epilepsy at a California level IV epilepsy center. J Neurosurg Pediatr. 2025 Sep 01; 36(3):318-329. Lai GY, Sullivan JE, Numis AL, Singhal NS, Gonzalez-Giraldo E, Bernardo D, Auguste KI. PMID: 40479817.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Machine learning for forecasting initial seizure onset in neonatal hypoxic-ischemic encephalopathy. Epilepsia. 2025 Jan; 66(1):89-103. Bernardo D, Kim J, Cornet MC, Numis AL, Scheffler A, Rao VR, Amorim E, Glass HC. PMID: 39495029; PMCID: PMC11742638.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Simulation-based inference of developmental EEG maturation with the spectral graph model. Commun Phys. 2024; 7(1):255. Bernardo D, Xie X, Verma P, Kim J, Liu V, Numis AL, Wu Y, Glass HC, Yap PT, Nagarajan SS, Raj A. PMID: 40756012; PMCID: PMC12310519.
      View in: PubMed   Mentions:
    10. Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness. Epilepsy Res. 2021 12; 178:106809. Miyakoshi M, Nariai H, Rajaraman RR, Bernardo D, Shrey DW, Lopour BA, Sim MS, Staba RJ, Hussain SA. PMID: 34823159; PMCID: PMC12289543.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. PIGG variant pathogenicity assessment reveals characteristic features within 19 families. Genet Med. 2021 10; 23(10):1873-1881. Tremblay-Laganière C, Maroofian R, Nguyen TTM, Karimiani EG, Kirmani S, Akbar F, Ibrahim S, Afroze B, Doosti M, Ashrafzadeh F, Babaei M, Efthymiou S, Christoforou M, Sultan T, Ladda RL, McLaughlin HM, Truty R, Mahida S, Cohen JS, Baranano K, Ismail FY, Patel MS, Lehman A, Edmondson AC, Nagy A, Walker MA, Mercimek-Andrews S, Maki Y, Sachdev R, Macintosh R, Palmer EE, Mancini GMS, Barakat TS, Steinfeld R, Rüsch CT, Stettner GM, Wagner M, Wortmann SB, Kini U, Brady AF, Stals KL, Ismayilova N, Ellard S, Bernardo D, Nugent K, McLean SD, Antonarakis SE, Houlden H, Kinoshita T, Campeau PM, Murakami Y. PMID: 34113002; PMCID: PMC9900493.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    12. Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms. Clin Neurophysiol. 2020 11; 131(11):2527-2536. Nariai H, Hussain SA, Bernardo D, Motoi H, Sonoda M, Kuroda N, Asano E, Nguyen JC, Elashoff D, Sankar R, Bragin A, Staba RJ, Wu JY. PMID: 32927206; PMCID: PMC7606823.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    13. Interictal scalp fast ripple occurrence and high frequency oscillation slow wave coupling in epileptic spasms. Clin Neurophysiol. 2020 07; 131(7):1433-1443. Bernardo D, Nariai H, Hussain SA, Sankar R, Wu JY. PMID: 32387963.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    14. Prospective observational study: Fast ripple localization delineates the epileptogenic zone. Clin Neurophysiol. 2019 11; 130(11):2144-2152. Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY. PMID: 31569042.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    15. Interrater reliability in visual identification of interictal high-frequency oscillations on electrocorticography and scalp EEG. Epilepsia Open. 2018 Dec; 3(Suppl Suppl 2):127-132. Nariai H, Wu JY, Bernardo D, Fallah A, Sankar R, Hussain SA. PMID: 30564771; PMCID: PMC6293061.
      View in: PubMed   Mentions: 15     Fields:    
    16. Automated Detection of High Frequency Oscillations in Human Scalp Electroencephalogram. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:3116-3119. Charupanit K, Nunez MD, Bernardo D, Bebin M, Krueger DA, Northrup H, Sahin M, Wu JY, Lopour BA. PMID: 30441054.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex. Clin Neurophysiol. 2018 07; 129(7):1458-1466. Bernardo D, Nariai H, Hussain SA, Sankar R, Salamon N, Krueger DA, Sahin M, Northrup H, Bebin EM, Wu JY, UCLA Pediatric Epilepsy Group, TACERN Study Group. PMID: 29673547.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    18. Toxoplasmic encephalitis during mycophenolate mofetil immunotherapy of neuromuscular disease. Neurol Neuroimmunol Neuroinflamm. 2015 Feb; 2(1):e63. Bernardo DR, Chahin N. PMID: 25635260; PMCID: PMC4309524.
      View in: PubMed   Mentions: 10     Fields:    
    19. Unsupervised learning of electrocorticography motifs with binary descriptors of wavelet features and hierarchical clustering. Annu Int Conf IEEE Eng Med Biol Soc. 2014; 2014:2657-60. Pluta T, Bernardo R, Shin HW, Bernardo DR. PMID: 25570537.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron. 2009 Aug 13; 63(3):342-56. Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernardo DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, Wetsel WC, Philpot BD, Pérez-Otaño I. PMID: 19679074; PMCID: PMC3448958.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    21. Ube3a is required for experience-dependent maturation of the neocortex. Nat Neurosci. 2009 Jun; 12(6):777-83. Yashiro K, Riday TT, Condon KH, Roberts AC, Bernardo DR, Prakash R, Weinberg RJ, Ehlers MD, Philpot BD. PMID: 19430469; PMCID: PMC2741303.
      View in: PubMed   Mentions: 189     Fields:    Translation:Animals
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