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Mercedes Paredes, MD, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address505 Parnassus Avenue
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.D.2007 Medicine
    University of California, San FranciscoPh.D.2007 Graduate Division (Neuroscience)

    Collapse Research 
    Collapse Research Activities and Funding
    Late-migrating interneurons in the postnatal brain
    NIH K08NS091537Sep 30, 2015 - Jun 30, 2020
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature. 2018 Mar 15; 555(7696):377-381. PMID: 29513649.
      View in: PubMed
    2. Priya R, Paredes MF, Karayannis T, Yusuf N, Liu X, Jaglin X, Graef I, Alvarez-Buylla A, Fishell G. Activity Regulates Cell Death within Cortical Interneurons through a Calcineurin-Dependent Mechanism. Cell Rep. 2018 Feb 13; 22(7):1695-1709. PMID: 29444424.
      View in: PubMed
    3. Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC. Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. Cereb Cortex. 2017 Apr 26; 1-13. PMID: 28449024.
      View in: PubMed
    4. Subramanian L, Bershteyn M, Paredes MF, Kriegstein AR. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017 Jan 31; 8:14167. PMID: 28139695.
      View in: PubMed
    5. Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH, Xu D, McQuillen PS, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A. Extensive migration of young neurons into the infant human frontal lobe. Science. 2016 Oct 07; 354(6308). PMID: 27846470.
      View in: PubMed
    6. Paredes MF, Sorrells SF, Garcia-Verdugo JM, Alvarez-Buylla A. Brain size and limits to adult neurogenesis. J Comp Neurol. 2016 Feb 15; 524(3):646-64. PMID: 26417888.
      View in: PubMed
    7. Höftberger R, van Sonderen A, Leypoldt F, Houghton D, Geschwind M, Gelfand J, Paredes M, Sabater L, Saiz A, Titulaer MJ, Graus F, Dalmau J. Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients. Neurology. 2015 Jun 16; 84(24):2403-12. PMID: 25979696; PMCID: PMC4478035.
    8. Hwang WW, Salinas RD, Siu JJ, Kelley KW, Delgado RN, Paredes MF, Alvarez-Buylla A, Oldham MC, Lim DA. Distinct and separable roles for EZH2 in neurogenic astroglia. Elife. 2014 May 27; 3:e02439. PMID: 24867641; PMCID: PMC4032491.
    9. Tong CK, Cebrián-Silla A, Paredes MF, Huang EJ, García-Verdugo JM, Alvarez-Buylla A. Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans. Neurogenesis (Austin). 2014 Jan 01; 1(1). PMID: 26413556.
      View in: PubMed
    10. Southwell DG, Paredes MF, Galvao RP, Jones DL, Froemke RC, Sebe JY, Alfaro-Cervello C, Tang Y, Garcia-Verdugo JM, Rubenstein JL, Baraban SC, Alvarez-Buylla A. Intrinsically determined cell death of developing cortical interneurons. Nature. 2012 Nov 01; 491(7422):109-13. PMID: 23041929; PMCID: PMC3726009.
    11. Li G, Berger O, Han SM, Paredes M, Wu NC, Pleasure SJ. Hilar mossy cells share developmental influences with dentate granule neurons. Dev Neurosci. 2008; 30(4):255-61. PMID: 17960053.
      View in: PubMed
    12. Berger O, Li G, Han SM, Paredes M, Pleasure SJ. Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev Neurosci. 2007; 29(1-2):48-58. PMID: 17148948.
      View in: PubMed
    13. Paredes MF, Li G, Berger O, Baraban SC, Pleasure SJ. Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains. J Neurosci. 2006 Sep 13; 26(37):9404-12. PMID: 16971524; PMCID: PMC2133346.
    14. Paredes M, Pleasure SJ, Baraban SC. Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia. J Comp Neurol. 2006 Mar 01; 495(1):133-48. PMID: 16432901; PMCID: PMC2827607.
    15. Calcagnotto ME, Paredes MF, Tihan T, Barbaro NM, Baraban SC. Dysfunction of synaptic inhibition in epilepsy associated with focal cortical dysplasia. J Neurosci. 2005 Oct 19; 25(42):9649-57. PMID: 16237169.
      View in: PubMed
    16. Paredes MF, Greenwood J, Baraban SC. Neuropeptide Y modulates a G protein-coupled inwardly rectifying potassium current in the mouse hippocampus. Neurosci Lett. 2003 Apr 03; 340(1):9-12. PMID: 12648746.
      View in: PubMed
    17. Calcagnotto ME, Paredes MF, Baraban SC. Heterotopic neurons with altered inhibitory synaptic function in an animal model of malformation-associated epilepsy. J Neurosci. 2002 Sep 01; 22(17):7596-605. PMID: 12196583.
      View in: PubMed
    18. Paredes MF, Baraban SC. A review of gene expression patterns in the malformed brain. Mol Neurobiol. 2002 Aug; 26(1):109-16. PMID: 12392060.
      View in: PubMed