Nilika Singhal, MD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address550 16th Street, #5205
San Francisco CA 94158
Phone415-502-2700
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of Texas Health Science Center at Houston, Houston, TXM.D.2007School of Medicine
    Children's Hospital of Philadelphia, Philadelphia, PA2009Pediatrics Residency
    UCSF, San Francisco, CA2012Child Neurology Residency
    UCSF, San Francisco, CA2013Epilepsy Fellowship
    University of California, San Francisco, CA2017Diversity, Equity, and Inclusion Champion Training
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    UCSF2016Haile T. Debas Academy of Medical Educators Excellence in Teaching Award
    UCSF2018  - 2019Bridges Curriculum Foundations 1&2 Teaching Award for Outstanding Coach
    UCSF2018  - 2019Finalist for the Henry J. Kaiser Awards for Excellence in Teaching

    Collapse Overview 
    Collapse Overview
    Nilika Singhal, MD is Associate Professor of Neurology at the University of California, San Francisco (UCSF). She specializes in the treatment of pediatric epilepsies, including early-life genetic epilepsies, surgical epilepsies, and focal epilepsies. She also specializes in the use of implantable medical devices in the treatment of epilepsy, use of dietary therapies, and treatment of status epilepticus. She is medical director for the UCSF Benioff Children's Hospital Clinical Documentation Integrity Program. She is a UCSF School of Medicine Bridges coach, and she is course director for the Inquiry Immersion course. She is a member of the Haile T Debas / UCSF Academy of Medical Educators. She is a Diversity, Equity and Inclusion champion. She ran the longitudinal neurology clerkship for medical students from 2016-2019. She has a passion for medical education, from direct teaching to education leadership.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. The influence of risk factors, biomarkers and care settings on SUDEP counseling. Epilepsy Behav. 2024 Jul; 156:109845. Valdrighi A, Laze J, Farooque P, Friedman D, Devinsky O, Singhal N, Hegde M. PMID: 38788665.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. Neurol Genet. 2024 Apr; 10(2):e200142. Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V. PMID: 38586598; PMCID: PMC10997208.
      View in: PubMed   Mentions:
    3. Health and Healthcare Disparities in Pediatric Epilepsy in the United States: A Scoping Review. Ann Neurol. 2024 Apr; 95(4):733-742. Skjei KL, Beatty C, Bhatia S, Garcia-Sosa R, Joshi C, Patel S, Singhal NS, Taylor C, Vetter IL, Wagner JL. PMID: 38303167.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Cell type specificity of mosaic chromosome 1q gain resolved by snRNA-seq in a case of epilepsy with hyaline protoplasmic astrocytopathy. bioRxiv. 2024 Jan 25. Leng K, Cadwell CR, Patrick Devine W, Tihan T, Qi Z, Singhal N, Glenn O, Kamiya S, Wiita A, Berger A, Shieh JT, Titus EW, Paredes MF, Upadhyay V. PMID: 38328093; PMCID: PMC10849466.
      View in: PubMed   Mentions:
    5. Epilepsy surgery as a treatment option for select patients with PCDH19-related epilepsy. Epilepsy Behav. 2023 Dec; 149:109517. Simmons R, Singhal N, Sullivan J, Shih T, Tihan T, Poduri A, Smith L, Yang E. PMID: 37956604.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. De novo KCNA6 variants with attenuated KV 1.6 channel deactivation in patients with epilepsy. Epilepsia. 2023 02; 64(2):443-455. Salpietro V, Galassi Deforie V, Efthymiou S, O'Connor E, Marcé-Grau A, Maroofian R, Striano P, Zara F, Morrow MM, SYNAPS Study Group, Reich A, Blevins A, Sala-Coromina J, Accogli A, Fortuna S, Alesandrini M, Au PYB, Singhal NS, Cogne B, Isidor B, Hanna MG, Macaya A, Kullmann DM, Houlden H, Männikkö R. PMID: 36318112; PMCID: PMC10108282.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Health Disparities in Pediatric Epilepsy: Methods and Lessons Learned. J Clin Psychol Med Settings. 2023 06; 30(2):251-260. Wagner J, Bhatia S, Marquis BO, Vetter I, Beatty CW, Garcia R, Joshi C, Kumar G, Rao K, Singhal N, Skjei K. PMID: 35930105; PMCID: PMC9362655.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022 07; 92(1):32-44. Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM, Pediatric Epilepsy Research Consortium, National Infantile Spasms Consortium. PMID: 35388521; PMCID: PMC9482145.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. J Child Neurol. 2022 03; 37(3):186-193. Knupp KG, Coryell J, Singh RK, Gaillard WD, Shellhaas RA, Koh S, Mitchell WG, Harini C, Millichap JJ, May A, Dlugos D, Nickels K, Mytinger JR, Keator C, Yozawitz E, Singhal N, Lockrow J, Thomas JF, Juarez-Colunga E. PMID: 35044272.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Repetitive transcranial magnetic stimulation (rTMS) as therapy in an infant with epilepsia partialis continua. Epilepsy Behav Rep. 2022; 18:100511. Chang D, Singhal NS, Tarapore PE, Auguste KI. PMID: 35198952; PMCID: PMC8850736.
      View in: PubMed   Mentions: 1  
    11. Longitudinal analysis of regional brain changes in anti-NMDAR encephalitis: a case report. BMC Neurol. 2021 Oct 27; 21(1):412. Nillo RM, Broce IJ, Uzgil B, Singhal NS, Glastonbury CM, Hess CP, Barkovich JA, Desikan RS, Sugrue LP. PMID: 34706674; PMCID: PMC8554978.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. Neurology. 2021 Sep 20; 97(12):e1217-e1228. Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell EC, Valencia I, Singhal NS, Nordli DR, Mytinger JR, Mitchell WG, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. PMID: 34266919; PMCID: PMC8480478.
      View in: PubMed   Mentions: 10     Fields:    
    13. Treatment Practices and Outcomes in Continuous Spike and Wave during Slow Wave Sleep: A Multicenter Collaboration. J Pediatr. 2021 05; 232:220-228.e3. Baumer FM, McNamara NA, Fine AL, Pestana-Knight E, Shellhaas RA, He Z, Arndt DH, Gaillard WD, Kelley SA, Nagan M, Ostendorf AP, Singhal NS, Speltz L, Chapman KE. PMID: 33484700; PMCID: PMC8934740.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    14. Design and implementation of electronic health record common data elements for pediatric epilepsy: Foundations for a learning health care system. Epilepsia. 2021 01; 62(1):198-216. Grinspan ZM, Patel AD, Shellhaas RA, Berg AT, Axeen ET, Bolton J, Clarke DF, Coryell J, Gaillard WD, Goodkin HP, Koh S, Kukla A, Mbwana JS, Morgan LA, Singhal NS, Storey MM, Yozawitz EG, Abend NS, Fitzgerald MP, Fridinger SE, Helbig I, Massey SL, Prelack MS, Buchhalter J, Pediatric Epilepsy Learning Healthcare System. PMID: 33368200; PMCID: PMC10508354.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    15. Pediatric Neurology. Semin Neurol. 2020 Jun; 40(3):275-276. Singhal NS, Nash KB. PMID: 32464674.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Pediatric Neurology. Semin Neurol. 2020 Apr; 40(2):175-176. Singhal NS, Nash KB. PMID: 32268414.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. SLC35A2-CDG: Functional characterization, expanded molecular, clinical, and biochemical phenotypes of 30 unreported Individuals. Hum Mutat. 2019 07; 40(7):908-925. Ng BG, Sosicka P, Agadi S, Almannai M, Bacino CA, Barone R, Botto LD, Burton JE, Carlston C, Chung BH, Cohen JS, Coman D, Dipple KM, Dorrani N, Dobyns WB, Elias AF, Epstein L, Gahl WA, Garozzo D, Hammer TB, Haven J, Héron D, Herzog M, Hoganson GE, Hunter JM, Jain M, Juusola J, Lakhani S, Lee H, Lee J, Lewis K, Longo N, Lourenço CM, Mak CCY, McKnight D, Mendelsohn BA, Mignot C, Mirzaa G, Mitchell W, Muhle H, Nelson SF, Olczak M, Palmer CGS, Partikian A, Patterson MC, Pierson TM, Quinonez SC, Regan BM, Ross ME, Guillen Sacoto MJ, Scaglia F, Scheffer IE, Segal D, Singhal NS, Striano P, Sturiale L, Symonds JD, Tang S, Vilain E, Willis M, Wolfe LA, Yang H, Yano S, Powis Z, Suchy SF, Rosenfeld JA, Edmondson AC, Grunewald S, Freeze HH. PMID: 30817854; PMCID: PMC6661012.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    18. Global Teleneurology Service: First Insights (P2.6-045). Neurology. 2019 Apr 9; 92(15_supplement). Bove BR, Arias AJ, Barnecut BA, Branagan BL, Chow CF, Gelfand GJ, Josephson JS, Katz KM, Lomen-Hoerth LC, Schleimer SE, Singhal SN, Wilson WM, Niyongabo NT, Norwood NA, Kaneza KC, Kohnen KE, Christensen CC, Van Leeuwen VJ. .
      View in: Publisher Site   Mentions:
    19. Direct cortical stimulation of inferior frontal cortex disrupts both speech and music production in highly trained musicians. Cogn Neuropsychol. 2019 May - Jun; 36(3-4):158-166. Leonard MK, Desai M, Hungate D, Cai R, Singhal NS, Knowlton RC, Chang EF. PMID: 29786470.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    20. Breaking the curve: moving from normative to criterion-based grading on neurology clerkship (S14.001). Neurology. 2018 Apr 10; 90(15_supplement). Brown BE, Garga GN, Richie RM, Singhal SN, Foster-Barber FA, Douglas DV. .
      View in: Publisher Site   Mentions:
    21. Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy. Epilepsy Behav Case Rep. 2018; 10:21-24. Singhal NS, Numis AL, Lee MB, Chang EF, Sullivan JE, Auguste KI, Rao VR. PMID: 30013930; PMCID: PMC6019859.
      View in: PubMed   Mentions: 18  
    22. PCDH19-related epilepsy is associated with a broad neurodevelopmental spectrum. Epilepsia. 2018 03; 59(3):679-689. Smith L, Singhal N, El Achkar CM, Truglio G, Rosen Sheidley B, Sullivan J, Poduri A. PMID: 29377098; PMCID: PMC6264912.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    23. 68 Epileptic Spasms and Myoclonic Seizures. Swaiman\u0027s Pediatric Neurology. 2017 Jan 1; 538-542. Singhal SN, Harini HC, Sullivan SJ. .
      View in: Publisher Site   Mentions:
    24. Clinical Reasoning: Seizures from the neglected lobe. Neurology. 2016 Mar 08; 86(10):e97-e100. Muhlhofer W, Paul B, Lin G, Singhal N. PMID: 26952306; PMCID: PMC4782116.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. Lancet Neurol. 2016 Mar; 15(3):270-8. Devinsky O, Marsh E, Friedman D, Thiele E, Laux L, Sullivan J, Miller I, Flamini R, Wilfong A, Filloux F, Wong M, Tilton N, Bruno P, Bluvstein J, Hedlund J, Kamens R, Maclean J, Nangia S, Singhal NS, Wilson CA, Patel A, Cilio MR. PMID: 26724101.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansCTClinical Trials
    26. Acute transverse myelitis and silent infection with Mycoplasma pneumoniae. Journal of Pediatric Neurology. 2015 Jul 30; 12(3):145-149. Grandhe GS, Marcus MJ, Singhal SN, Gardner GM, Waubant WE. .
      View in: Publisher Site   Mentions:
    27. Continuous Spike-Wave during Slow Wave Sleep and Related Conditions. ISRN Neurol. 2014; 2014:619079. Singhal NS, Sullivan JE. PMID: 24634784; PMCID: PMC3929187.
      View in: PubMed   Mentions: 11  
    28. Idiopathic basal ganglia calcifications: an atypical presentation of PKAN. Pediatr Neurol. 2013 Nov; 49(5):351-4. Wu YW, Hess CP, Singhal NS, Groden C, Toro C. PMID: 23968566.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    29. Role of trauma and infection in childhood hemorrhagic stroke due to vascular lesions. Neurology. 2013 Aug 06; 81(6):581-4. Singhal NS, Hills NK, Sidney S, Fullerton HJ. PMID: 23825175; PMCID: PMC3775687.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. PCDH19-related epilepsy. Journal of Pediatric Epilepsy. 2012 Sep 1; 01(03):179-184. Singhal SN. .
      View in: Publisher Site   Mentions:
    31. Alexander Disease: Demonstration on Neuroimaging. Neurological Bulletin. 2012 Jan 1; 4(1):45-46. Singhal SN, Foster-Barber FA. .
      View in: Publisher Site   Mentions:
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