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Aaron Scheffler, PhD, MS

Title(s)Assistant Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Address550 16th. Street
San Francisco CA 94158
Phone--
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    University of California, Los AngelesPhD2019Biostatistics
    University of California, Los AngelesMS2015Biostatistics
    Columbia UniversityBA2011Biochemistry

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    My research centers on the statistical challenges posed by highly structured data collected in an increasing number of applications ranging from imaging to wearable technologies. Frequently, the observed data are discrete samples of an underlying functional process which exhibits complex dependencies that are difficult to capture using traditional statistical models. A central theme in my research is to provide computationally efficient methods for these rich data structures that maintain information along each dimension while simultaneously providing interpretable components and inferences. In addition, I apply techniques from statistics and machine learning including mixed effects models, gradient boosting, and tree based methods, to assist collaborators in psychiatry, neurology, oncology, and HIV/AIDS research.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Day-to-Day Test-Retest Reliability of EEG Profiles in Children With Autism Spectrum Disorder and Typical Development. Front Integr Neurosci. 2020; 14:21. Levin AR, Naples AJ, Scheffler AW, Webb SJ, Shic F, Sugar CA, Murias M, Bernier RA, Chawarska K, Dawson G, Faja S, Jeste S, Nelson CA, McPartland JC, Sentürk D. PMID: 32425762.
      View in: PubMed   Mentions:
    2. Hybrid principal components analysis for region-referenced longitudinal functional EEG data. Biostatistics. 2020 01 01; 21(1):139-157. Scheffler A, Telesca D, Li Q, Sugar CA, Distefano C, Jeste S, Sentürk D. PMID: 30084925.
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    3. Covariate-adjusted region-referenced generalized functional linear model for EEG data. Stat Med. 2019 12 30; 38(30):5587-5602. Scheffler AW, Telesca D, Sugar CA, Jeste S, Dickinson A, DiStefano C, Sentürk D. PMID: 31659786.
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    4. Developmental Trajectories of Infants With Multiplex Family Risk for Autism: A Baby Siblings Research Consortium Study. JAMA Neurol. 2019 Oct 07. McDonald NM, Senturk D, Scheffler A, Brian JA, Carver LJ, Charman T, Chawarska K, Curtin S, Hertz-Piccioto I, Jones EJH, Klin A, Landa R, Messinger DS, Ozonoff S, Stone WL, Tager-Flusberg H, Webb SJ, Young G, Zwaigenbaum L, Jeste SS. PMID: 31589284.
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    5. A germline microRNA-based biomarker signature of immune-associated toxicity to anti-PD1/PDL1 therapy. Journal of Clinical Oncology. 2019 Mar 10; 37(8_suppl):96-96. Joanne B. Weidhaas, Aaron Wolfe Scheffler, David Salzman, Anusha Kalbasi, Kirk Wilenius, Emily Rietdorf, Mara Heilig, Mattias Pitka, Caroline Desler, Dan Ruan, Antoni Ribas, Alexandra Drakaki, Mark C. Scholz, Donatello Telesca. .
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    6. Interhemispheric alpha-band hypoconnectivity in children with autism spectrum disorder. Behav Brain Res. 2018 08 01; 348:227-234. Dickinson A, DiStefano C, Lin YY, Scheffler AW, Senturk D, Jeste SS. PMID: 29689375.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Maternal patterns of antenatal and postnatal depressed mood and the impact on child health at 3-years postpartum. J Consult Clin Psychol. 2018 03; 86(3):218-230. Rotheram-Fuller EJ, Tomlinson M, Scheffler A, Weichle TW, Hayati Rezvan P, Comulada WS, Rotheram-Borus MJ. PMID: 29504791.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. A microRNA-based signature predicting immune-related toxicity (iRAEs) to pembrolizumab in prostate cancer patients. Journal of Clinical Oncology. 2018 Feb 20; 36(6_suppl):269-269. Joanne B. Weidhaas, Kirk Wilenius, Aaron Wolfe Scheffler, Juliana Higa, Donatello Telesca, Mark C. Scholz. .
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    9. Antenatal depressed mood and child cognitive and physical growth at 18-months in South Africa: a cluster randomised controlled trial of home visiting by community health workers. Epidemiol Psychiatr Sci. 2018 Dec; 27(6):601-610. Tomlinson M, Rotheram-Borus MJ, Scheffler A, le Roux I. PMID: 28606206.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Adjustment of a Population of South African Children of Mothers Living With/and Without HIV Through Three Years Post-Birth. AIDS Behav. 2017 Jun; 21(6):1601-1610. Rotheram-Borus MJ, Tomlinson M, Scheffler A, Harris DM, Nelson S. PMID: 27260178.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. A multi-dimensional functional principal components analysis of EEG data. Biometrics. 2017 09; 73(3):999-1009. Hasenstab K, Scheffler A, Telesca D, Sugar CA, Jeste S, DiStefano C, Sentürk D. PMID: 28072468.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Thirty-Six-Month Outcomes of a Generalist Paraprofessional Perinatal Home Visiting Intervention in South Africa on Maternal Health and Child Health and Development. Prev Sci. 2016 11; 17(8):937-948. Tomlinson M, Rotheram-Borus MJ, le Roux IM, Youssef M, Nelson SH, Scheffler A, Weiss RE, O'Connor M, Worthman CM. PMID: 27438294.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Drug use and emotional distress differentiate unstably- versus stably-housed adults living with HIV who engage in unprotected sex. J Health Psychol. 2017 03; 22(3):302-313. Arnold EM, Desmond KA, Rotheram-Borus MJ, Scheffler A, Comulada WS, Johnson MO, Kelly JA. PMID: 26359286.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Re-engagement in HIV care among mothers living with HIV in South Africa over 36 months post-birth. AIDS. 2015 Nov; 29(17):2361-2. Rotheram-Borus MJ, Tomlinson M, Scheffler A, Le Roux IM. PMID: 26258526.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    15. Smartphone self-monitoring to support self-management among people living with HIV: perceived benefits and theory of change from a mixed-methods randomized pilot study. J Acquir Immune Defic Syndr. 2015 May 01; 69 Suppl 1:S80-91. Swendeman D, Ramanathan N, Baetscher L, Medich M, Scheffler A, Comulada WS, Estrin D. PMID: 25867783.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
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