Dylan Chan, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
Address513 Parnassus Ave
San Francisco CA 94143
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    Dylan K. Chan, MD, PhD, is an Assistant Professor in Residence and he is the Director of the Children’s Communication Center (CCC) in the Department of Otolaryngology – Head and Neck Surgery (ONHS) at the University of California, San Francisco. He received his PhD in Sensory Neuroscience from the Rockefeller University in New York, and he obtained his medical degree from Weill Medical College of Cornell University, New York. Dr. Chan completed his ONHS residency from Stanford University School of Medicine, California, followed by a Pediatric Otolaryngology fellowship at the Seattle Children’s Hospital, Washington.

    In 2014, Dr. Chan established the UCSF Children’s Communication Center, which is devoted to delivering multidisciplinary care for families of deaf and hard of hearing children, performing community outreach and education, and conducting clinical and translational research projects. By addressing existing shortfalls in care delivery and developing novel treatments, he hopes to significantly impact hearing health in children. His laboratory is interested in investigating the pathophysiology and genetics of hearing loss associated with mutations in Connexin 26, the most commonly affected gene in congenital hearing loss, and the development of gene therapy for hearing restoration.

    Dr. Chan is a scientific reviewer for various scientific journals, frequent invited speaker at local and national conferences, and has published over 15 articles

    Cochlear Implant Surgery and Pediatric Otolaryngology

    Pediatric hearing loss, cochlear implantation, chronic ear surgery, and ear canal reconstruction; obstructive sleep apnea and sleep endoscopy; velopharyngeal insufficiency

    Professional Interests:
    Multidisciplinary management, diagnostic testing, genetics, and treatment of deaf and hard of hearing children; health disparities in treatment and outcomes of pediatric hearing loss; pathophysiology and genetics of Connexin-26-associated hearing loss; pediatric communication disorders.

    Education and Training:
    • PhD: The Rockefeller University, New York, NY – Sensory Neuroscience
    • Medical School: Weill Medical College of Cornell University, New York, NY
    • Residency: Stanford University School of Medicine, CA – Otolaryngology-Head and Neck Surgery
    • Fellowship: Seattle Children’s Hospital, WA – Pediatric Otolaryngology

    Awards and Honors:
    • 2014 ANS/AAO-HNSF - Herbert Silverstein Award
    • 2014 American Hearing Research Foundation Research Grant
    • 2015 American Society for Pediatric Otolaryngology Career Development Award

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cedars E, Chan D, Meyer A, Rosbe K. Response to Letter to the Editor. Int J Pediatr Otorhinolaryngol. 2016 Dec 27. PMID: 28081872.
      View in: PubMed
    2. Miller C, Purcell PL, Dahl JP, Johnson K, Horn DL, Chen ML, Chan D, Parikh SR. Clinically small tonsils are typically not obstructive in children during drug-induced sleep endoscopy. Laryngoscope. 2016 Dec 23. PMID: 28008627.
      View in: PubMed
    3. Chan D, Rouse SL. Sound-Induced Intracellular Ca2+ Dynamics in the Adult Hearing Cochlea. PLoS One. 2016; 11(12):e0167850. PMID: 27959894.
      View in: PubMed
    4. Cedars E, Chan D, Lao A, Hardies L, Meyer A, Rosbe K. Conversion of traditional osseointegrated bone-anchored hearing aids to the Baha(®) attract in four pediatric patients. Int J Pediatr Otorhinolaryngol. 2016 Dec; 91:37-42. PMID: 27863639.
      View in: PubMed
    5. Chan D, McNamara S, Park JS, Vajda J, Gibson RL, Parikh SR. Sinonasal Quality of Life in Children With Cystic Fibrosis. JAMA Otolaryngol Head Neck Surg. 2016 Aug 1; 142(8):743-9. PMID: 27228505.
      View in: PubMed
    6. Meiklejohn DA, Chan D, Lalakea ML. Occult central venous stenosis leading to airway obstruction after subtotal parathyroidectomy. Ear Nose Throat J. 2016 Jul; 95(7):E11-3. PMID: 27434479.
      View in: PubMed
    7. Friedman NR, Parikh SR, Ishman SL, Ruiz AG, El-Hakim H, Ulualp SO, Wootten CT, Koltai PJ, Chan D. The current state of pediatric drug-induced sleep endoscopy. Laryngoscope. 2017 Jan; 127(1):266-272. PMID: 27311407.
      View in: PubMed
    8. Dahl JP, Miller C, Purcell PL, Zopf DA, Johnson K, Horn DL, Chen ML, Chan D, Parikh SR. Airway Obstruction during Drug-Induced Sleep Endoscopy Correlates with Apnea-Hypopnea Index and Oxygen Nadir in Children. Otolaryngol Head Neck Surg. 2016 Oct; 155(4):676-80. PMID: 27301902.
      View in: PubMed
    9. Alemi AS, Rosbe KW, Chan D, Meyer AK. Airway response to sirolimus therapy for the treatment of complex pediatric lymphatic malformations. Int J Pediatr Otorhinolaryngol. 2015 Dec; 79(12):2466-9. PMID: 26549380.
      View in: PubMed
    10. Alemi AS, Chan D. Progressive Hearing Loss and Head Trauma in Enlarged Vestibular Aqueduct: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2015 Oct; 153(4):512-7. PMID: 26204902.
      View in: PubMed
    11. Akil O, Rouse SL, Chan D, Lustig LR. Surgical method for virally mediated gene delivery to the mouse inner ear through the round window membrane. J Vis Exp. 2015; (97). PMID: 25867531.
      View in: PubMed
    12. Chan D, Liming BJ, Horn DL, Parikh SR. A new scoring system for upper airway pediatric sleep endoscopy. JAMA Otolaryngol Head Neck Surg. 2014 Jul; 140(7):595-602. PMID: 24810174.
      View in: PubMed
    13. Chan D, Parikh SR. Perioperative ketorolac increases post-tonsillectomy hemorrhage in adults but not children. Laryngoscope. 2014 Aug; 124(8):1789-93. PMID: 24338331.
      View in: PubMed
    14. Brown JC, Baik FM, Ou HC, Otjen JP, Parish HG, Chan D. Upper aerodigestive magnetic foreign bodies in children. Laryngoscope. 2014 Jun; 124(6):1481-5. PMID: 24391087.
      View in: PubMed
    15. Chan D, Chang KW. GJB2-associated hearing loss: systematic review of worldwide prevalence, genotype, and auditory phenotype. Laryngoscope. 2014 Feb; 124(2):E34-53. PMID: 23900770.
      View in: PubMed
    16. Chan D, Jan TA, Koltai PJ. Effect of obesity and medical comorbidities on outcomes after adjunct surgery for obstructive sleep apnea in cases of adenotonsillectomy failure. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):891-6. PMID: 23069817.
      View in: PubMed
    17. Chan D, Truong MT, Koltai PJ. Supraglottoplasty for occult laryngomalacia to improve obstructive sleep apnea syndrome. Arch Otolaryngol Head Neck Surg. 2012 Jan; 138(1):50-4. PMID: 22249629.
      View in: PubMed
    18. Chan D, Schrijver I, Chang KW. Diagnostic yield in the workup of congenital sensorineural hearing loss is dependent on patient ethnicity. Otol Neurotol. 2011 Jan; 32(1):81-7. PMID: 21042228.
      View in: PubMed
    19. Chan D, Schrijver I, Chang KW. Connexin-26-associated deafness: phenotypic variability and progression of hearing loss. Genet Med. 2010 Mar; 12(3):174-81. PMID: 20154630.
      View in: PubMed
    20. Chan D, Lieberman DM, Musatov S, Goldfein JA, Selesnick SH, Kaplitt MG. Protection against cisplatin-induced ototoxicity by adeno-associated virus-mediated delivery of the X-linked inhibitor of apoptosis protein is not dependent on caspase inhibition. Otol Neurotol. 2007 Apr; 28(3):417-25. PMID: 17211286.
      View in: PubMed
    21. Asai Y, Chan D, Starr CJ, Kappler JA, Kollmar R, Hudspeth AJ. Mutation of the atrophin2 gene in the zebrafish disrupts signaling by fibroblast growth factor during development of the inner ear. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9069-74. PMID: 16754885; PMCID: PMC1474007.
    22. Cooper LB, Chan D, Roediger FC, Shaffer BR, Fraser JF, Musatov S, Selesnick SH, Kaplitt MG. AAV-mediated delivery of the caspase inhibitor XIAP protects against cisplatin ototoxicity. Otol Neurotol. 2006 Jun; 27(4):484-90. PMID: 16791039.
      View in: PubMed
    23. Chan D, Hudspeth AJ. Ca2+ current-driven nonlinear amplification by the mammalian cochlea in vitro. Nat Neurosci. 2005 Feb; 8(2):149-55. PMID: 15643426; PMCID: PMC2151387.
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