Yaron Gesthalter, MD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address521 Parnassus Avenue, #6228
San Francisco CA 94117
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    Collapse Biography 
    Collapse Education and Training
    BIDMC/MGH Harvard School of Medicine, Boston, MAFellowship in Interventional Pulmonary Medicine2017
    Boston University School of Medicine - Division of Computational Biomedicine, Boston, MAResearch Fellowship2016
    Boston University School of Medicine - Dept of Pulmonary & Critical Care, Boston, MAFellowship in Pulmonary and Critical Care2015
    Yale School of Medicine - Dept of Internal Medicine, New Haven, CTResidency2011
    Tel-Aviv University Sackler School of Medicine, IsraelMD2008
    Hebrew University of Jerusalem, IsraelB.Sc2003
    Collapse Awards and Honors
    University of California San Francisco 2023Michael Stulbarg Outstanding Teacher Award
    University of California San Francisco - Haile T. Debas Academy of Medical Educators2019Excellence in Teaching Award
    American Thoracic Society2016Thoracic Oncology Assembly Abstract Scholarship

    Collapse Overview 
    Collapse Overview
    I am a Pulmonologist and Critical Care Medicine physician with sub-specialty training in Interventional Pulmonary Medicine. Using minimally invasive techniques such as endobronchial ultrasound (EBUS) and navigational bronchoscopy I diagnose and stage patients with concerning lesions. For those with symptoms related to airway obstructions (from either malignant tumor invasion or non-malignant strictures) I use various ablative techniques to relieve airway obstruction. I also treat patients with pleural disease while emphasizing outpatient care. Additionally, I attend on the UCSF pulmonary consult service and in the intensive care units.

    My research relates to the early detection and prevention of lung cancer through minimally invasive ways. My research spans translational and computational approaches as well as clinical trials.

    In order to schedule an appointment with Dr Gesthalter at the UCSF Interventional Pulmonary clinic please call (415)885-3882. Please bring all available images (cat scans, PET scans) on CDs at the time of consultation to facilitate care.

    Clinical Expertise
    • Thoracic malignancies
    • Lung nodules
    • Symptom management
    • Diagnostic and staging procedures
    • Complex pleural effusions – ultrasound, thoracentesis, chest tubes, tunneled pleural catheters, medical thoracoscopy
    • Ablative bronchoscopic techniques (cryo- surgery, electrosurgery, argon plasma coagulation (APC), cryospray, photodynamic therapy)
    • Advanced bronchoscopy (electromagnetic navigation bronchoscopy (EMN), endobronchial ultrasound (EBUS), rigid bronchoscopy)
    • Fiducial placement for radiation therapy
    • Sarcoidosis and other non-malignant lung pathologies
    • Tracheal and bronchial obstructions
    • Tracheal and bronchial stent placement

    Research Interests
    • Lung cancer diagnostics
    • Bioinformatics
    • Application of minimally invasive diagnostic and therapeutic techniques
    • Lung cancer screening
    • Smoking cessation
    • Management of lung transplant related airway and pleural disease

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Assessment of Advanced Diagnostic Bronchoscopy Outcomes for Peripheral Lung Lesions: A Delphi Consensus Definition of Diagnostic Yield and Recommendations for Patient-centered Study Designs. An Official American Thoracic Society/American College of Chest Physicians Research Statement. Am J Respir Crit Care Med. 2024 Mar 15; 209(6):634-646. Gonzalez AV, Silvestri GA, Korevaar DA, Gesthalter YB, Almeida ND, Chen A, Gilbert CR, Illei PB, Navani N, Pasquinelli MM, Pastis NJ, Sears CR, Shojaee S, Solomon SB, Steinfort DP, Maldonado F, Rivera MP, Yarmus LB. PMID: 38394646; PMCID: PMC10945060.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Education for Tobacco Use Disorder Treatment: Current State, Evidence, and Unmet Needs. ATS Sch. 2023 Dec; 4(4):546-566. Melzer AC, Reese ZA, Mascarhenas L, Clancy CB, Deepak J, Gogineni H, Gesthalter Y, Hart JL. PMID: 38196686; PMCID: PMC10773493.
      View in: PubMed   Mentions:
    3. Interventional Pulmonology: Extending the Breadth of Thoracic Care. Annu Rev Med. 2024 Jan 29; 75:263-276. Gesthalter YB, Channick CL. PMID: 37827195.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
      View in: Publisher Site   Mentions:
    5. Safety and utility of indwelling pleural catheters in lung transplant recipients. Clin Transplant. 2023 10; 37(10):e15056. Trindade AJ, Lentz RJ, Gannon WD, Rickman OB, Shojaee S, Vandervest K, Schwartz G, Li GW, Kumar A, Garcha PS, Seeley EJ, Gesthalter YB, Mueller S, Egan JP, DeMaio AJ, Yarmus LB, Josan ES, Pannu JK, Wayne MT, DeCardenas JL, Bacchetta MD, Maldonado F, Interventional Pulmonary Outcomes Group. PMID: 37354125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Medical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World. Ann Am Thorac Soc. 2023 06; 20(6):781-784. Lee AG, Maley J, Hibbert K, Akgün KM, Hauschildt KE, Law A, Kaminski N, Hayes M, Gesthalter Y, Bosslet GT, Santhosh L, Witkin A, Hills-Dunlap K, Çoruh B, Gershengorn HB, Hardin CC. PMID: 36812378; PMCID: PMC10257035.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Real-World Perspectives and Practices for Pneumonitis/Interstitial Lung Disease Associated With Trastuzumab Deruxtecan Use in Human Epidermal Growth Factor Receptor 2-Expressing Metastatic Breast Cancer. JCO Oncol Pract. 2023 08; 19(8):539-546. Rugo HS, Crossno CL, Gesthalter YB, Kelley K, Moore HB, Rimawi MF, Westbrook KE, Buys SS. PMID: 37207306; PMCID: PMC10424906.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Impact of a Dedicated Pleural Clinic on Indwelling Pleural Catheter Related Outcomes: A Retrospective Single Center Experience. J Bronchology Interv Pulmonol. 2023 Apr 01; 30(2):114-121. Malcolm KB, Seeley EJ, Gesthalter YB. PMID: 36192832.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Use of tunneled pleural catheters in chronic empyema: Two case reports and brief review of the literature. Respir Med Case Rep. 2022; 40:101754. Krumm IR, Gesthalter YB. PMID: 36246015; PMCID: PMC9563632.
      View in: PubMed   Mentions:
    10. Tracheal Reconstruction Using Endotracheal Stent and Pectoralis Major Muscle Flap. . 2022 Sep 1. Abbasi AA, Alcon AA, Patel PA, Gesthalter GY, Hoffman HW, Kratz KJ. .
      View in: Publisher Site   Mentions:
    11. Acquired Benign Tracheoesophageal Fistula: Novel Use of a Nasal Septal Occluder. J Bronchology Interv Pulmonol. 2022 07 01; 29(3):e38-e43. Bawaadam HS, Russell M, Gesthalter YB. PMID: 35730784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Bleeding Risk With Combination Intrapleural Fibrinolytic and Enzyme Therapy in Pleural Infection: An International, Multicenter, Retrospective Cohort Study. Chest. 2022 Dec; 162(6):1384-1392. Akulian J, Bedawi EO, Abbas H, Argento C, Arnold DT, Balwan A, Batra H, Uribe Becerra JP, Belanger A, Berger K, Burks AC, Chang J, Chrissian AA, DiBardino DM, Fuentes XF, Gesthalter YB, Gilbert CR, Glisinski K, Godfrey M, Gorden JA, Grosu H, Gupta M, Kheir F, Ma KC, Majid A, Maldonado F, Maskell NA, Mehta H, Mercer J, Mullon J, Nelson D, Nguyen E, Pickering EM, Puchalski J, Reddy C, Revelo AE, Roller L, Sachdeva A, Sanchez T, Sathyanarayan P, Semaan R, Senitko M, Shojaee S, Story R, Thiboutot J, Wahidi M, Wilshire CL, Yu D, Zouk A, Rahman NM, Yarmus L, Interventional Pulmonary Outcomes Group. PMID: 35716828; PMCID: PMC9773231.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    13. Immunosuppression-Induced Pulmonary Alveolar Proteinosis Following Bilateral Lung Transplantation. The Journal of Heart and Lung Transplantation. 2022 Apr 1; 41(4):s298. Maheshwari MJ, Perez PA, Kolaitis KN, Calabrese CD, Estrada EA, Golden GJ, Shah SR, Leard LL, Kleinhenz KM, Jones JK, Urisman UA, Kukreja KJ, Trinh TB, Gesthalter GY, Singer SJ, Hays HS. .
      View in: Publisher Site   Mentions:
    14. Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022 04; 20(4):387-405. Thompson JA, Schneider BJ, Brahmer J, Achufusi A, Armand P, Berkenstock MK, Bhatia S, Budde LE, Chokshi S, Davies M, Elshoury A, Gesthalter Y, Hegde A, Jain M, Kaffenberger BH, Lechner MG, Li T, Marr A, McGettigan S, McPherson J, Medina T, Mohindra NA, Olszanski AJ, Oluwole O, Patel SP, Patil P, Reddy S, Ryder M, Santomasso B, Shofer S, Sosman JA, Wang Y, Zaha VG, Lyons M, Dwyer M, Hang L. PMID: 35390769.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    15. Ambulatory Management of a Recurrent Pneumothorax With an Indwelling Tunneled Pleural Catheter. J Bronchology Interv Pulmonol. 2022 04 01; 29(2):e15-e18. Bawaadam HS, Boberg M, Gesthalter YB. PMID: 35318990.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Erector Spinae Plane Block: A Novel Anesthetic Approach for Pleuroscopy. J Bronchology Interv Pulmonol. 2022 Apr 01; 29(2):109-114. Sharp A, Mudda G, Braehler MR, Gesthalter YB. PMID: 35318987.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Treatment of Advanced-Stage Non-Small Cell Lung Cancer. Am J Respir Crit Care Med. 2022 03 01; 205(5):P9-P10. Gesthalter Y, Smyth R, Sullivan D. PMID: 35230219.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Treatment of Early-Stage Non-Small Cell Lung Cancer. Am J Respir Crit Care Med. 2022 02 15; 205(4):P7-P8. Gesthalter Y, Smyth R, Sullivan D. PMID: 35166649.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Treatment of Small Cell Lung Cancer. Am J Respir Crit Care Med. 2022 01 15; 205(2):P3-P4. Gesthalter Y, Smyth R. PMID: 35029526.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Keep it Clean: Novel Use of Sterile Disposable Flexible Bronchoscopes for Pleuroscopy. J Bronchology Interv Pulmonol. 2022 Jan 01; 29(1):e2-e4. Hamilton BCS, Gesthalter YB. PMID: 34935673.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Lung Cancer Screening. Am J Respir Crit Care Med. 2021 12 01; 204(11):P19-P20. Gesthalter YB, Seeley EJ. PMID: 34851229.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation. J Thorac Dis. 2021 Jul; 13(7):4228-4235. Ivanick NM, Shrestha P, Podolsky MJ, Walavalkar V, Lucas CH, Gesthalter YB, Seeley EJ. PMID: 34422351; PMCID: PMC8339750.
      View in: PubMed   Mentions:
    23. Smoking Cessation and Cancer. Am J Respir Crit Care Med. 2021 05 15; 203(10):P24-P25. Gesthalter Y, Kathuria H, Moazed F, Tobacco Action Committee of the American Thoracic Society. PMID: 34014803.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Decreasing 30-day Readmissions for Pleural Effusions after Lung Transplant. The Journal of Heart and Lung Transplantation. 2021 Apr 1; 40(4):s382-s383. Teraoka TJ, Nguyen NK, Hart HD, Peace PS, Leard LL, Iyer IG, Gordon GD, Zuckerman ZB, Pascual PJ, Ponzo PJ, Perez PA, Budanova BN, Gesthalter GY, Trinh TB, Kukreja KJ, Hays HS, Venado VA. .
      View in: Publisher Site   Mentions:
    25. Key Highlights From the American Association for Bronchology and Interventional Pulmonology Evidence-Informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters. Chest. 2021 03; 159(3):920-923. Miller CRJ, Chrissian AA, Lee YCG, Rahman NM, Wahidi MM, Tremblay A, Hsia DW, Almeida FA, Shojaee S, Mudambi L, Belanger AR, Bedi H, Gesthalter YB, Gaynor M, MacKenney KL, Lewis SZ, Casal RF. PMID: 33152319.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. AABIP Evidence-informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters. J Bronchology Interv Pulmonol. 2020 Oct; 27(4):229-245. Miller RJ, Chrissian AA, Lee YCG, Rahman NM, Wahidi MM, Tremblay A, Hsia DW, Almeida FA, Shojaee S, Mudambi L, Belanger AR, Bedi H, Gesthalter YB, Gaynor M, MacKenney KL, Lewis SZ, Casal RF. PMID: 32804745.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 09 03; 182(5):1232-1251.e22. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576; PMCID: PMC7484178.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansCells
    28. Abstract 3377: NSCLC subtype-associated molecular and cellular alterations in the normal-appearing bronchial epithelium. Cancer Research. 2020 Aug 15; 80(16_Supplement):3377-3377. Shi SX, Zhang ZJ, Callori CS, Campbell CJ, Fine FD, Gesthalter GY, Liu LG, Xiao XX, Spira SA, Lenburg LM, Beane BJ. .
      View in: Publisher Site   Mentions:
    29. Flexible Bronchoscopic Deployment of a Silicone Bronchial Stent. J Bronchology Interv Pulmonol. 2020 Jan; 27(1):e10-e12. Gesthalter YB, Seeley EJ. PMID: 31856015.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv. 2019 12; 5(12):eaaw3413. Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, Campbell JD, Beane J. PMID: 31844660; PMCID: PMC6905872.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    31. Indwelling Tunneled Pleural Catheters. Am J Respir Crit Care Med. 2019 12 01; 200(11):P20-P21. Kheir F, Akulian J, Gesthalter YB. PMID: 31774312.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Cryoprobe retrieval of an airway foreign body: A case report and literature review. Int J Pediatr Otorhinolaryngol. 2019 Oct; 125:79-81. David AP, Xu MJ, Rosbe KW, Meyer AK, Gesthalter YB, Chan DK. PMID: 31271971.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Treatment of persistent bronchopleural fistula with a manually modified endobronchial stent: a case-report and brief literature review. J Thorac Dis. 2018 Oct; 10(10):5960-5963. de Lima A, Holden V, Gesthalter Y, Kent MS, Parikh M, Majid A, Chee A. PMID: 30505507; PMCID: PMC6236168.
      View in: PubMed   Mentions: 3  
    34. Pulmonary Sclerosing Pneumocytoma. J Bronchology Interv Pulmonol. 2018 10; 25(4):e54-e56. Rivera E, Gesthalter Y, VanderLaan P, Parikh MS. PMID: 30247298.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Bronchoscopic Management of Endobronchial Tumor in Patient With Hemoptysis and Acute Myocardial Infarction. J Bronchology Interv Pulmonol. 2018 07; 25(3):e37-e39. Perez C, Kheir F, Barry M, Gesthalther Y, Majid A. PMID: 29944595.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Impact of acute exposure to cigarette smoke on airway gene expression. Physiol Genomics. 2018 09 01; 50(9):705-713. Billatos E, Faiz A, Gesthalter Y, LeClerc A, Alekseyev YO, Xiao X, Liu G, Ten Hacken NHT, Heijink IH, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. PMID: 29932825; PMCID: PMC6172616.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    37. Sarcoidosis With Pleural Effusion as the Presenting Symptom. J Bronchology Interv Pulmonol. 2018 Apr; 25(2):148-151. Rivera E, Gesthalter Y, Vardelaan P, Chee A, Majid A. PMID: 29346252.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    38. Evaluations of Implementation at Early-Adopting Lung Cancer Screening Programs: Lessons Learned. Chest. 2017 07; 152(1):70-80. Gesthalter YB, Koppelman E, Bolton R, Slatore CG, Yoon SH, Cain HC, Tanner NT, Au DH, Clark JA, Wiener RS. PMID: 28223153.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    39. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016 Dec; 9(12):906-914. Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild A, Lenburg ME, Ionescu DN, Mayo J, Yi JE, Tazelaar H, Harmsen WS, Smith J, Spira AE, Beane J, Limburg PJ, Szabo E, Cancer Prevention Network. PMID: 27658890; PMCID: PMC5136333.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    40. A Call to Formalize Training in Tobacco Dependence Treatment for Pulmonologists. Ann Am Thorac Soc. 2016 Apr; 13(4):460-1. Gesthalter YB, Wiener RS, Kathuria H. PMID: 27058182.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Translating the transcriptome into tools for the early detection and prevention of lung cancer. Thorax. 2015 May; 70(5):476-81. Gesthalter YB, Vick J, Steiling K, Spira A. PMID: 25628310.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    42. Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers (Basel). 2014 May 16; 6(2):1157-79. Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K. PMID: 24840047; PMCID: PMC4074822.
      View in: PubMed   Mentions: 13  
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