Yaron Gesthalter, MD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
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    Collapse Biography 
    Collapse Education and Training
    BIDMC/MGH Harvard School of Medicine, Boston, MAFellowship in Interventional Pulmonary Medicine2017
    Boston University School of Medicine - Division of Computational Biomedicine, Boston, MAResearch Fellowship2016
    Boston University School of Medicine - Dept of Pulmonary & Critical Care, Boston, MAFellowship in Pulmonary and Critical Care2015
    Yale School of Medicine - Dept of Internal Medicine, New Haven, CTResidency2011
    Tel-Aviv University Sackler School of Medicine, IsraelMD2008
    Hebrew University of Jerusalem, IsraelB.Sc2003
    Collapse Awards and Honors
    University of California San Francisco - Haile T. Debas Academy of Medical Educators2019Excellence in Teaching Award
    American Thoracic Society2016Thoracic Oncology Assembly Abstract Scholarship

    Collapse Overview 
    Collapse Overview
    I am a Pulmonologist and Critical Care Medicine physician with sub-specialty training in Interventional Pulmonary Medicine. Using minimally invasive techniques such as endobronchial ultrasound (EBUS) and navigational bronchoscopy I diagnose and stage patients with concerning lesions. For those with symptoms related to airway obstructions (from either malignant tumor invasion or non-malignant strictures) I use various ablative techniques to relieve airway obstruction. I also treat patients with pleural disease while emphasizing outpatient care. Additionally, I attend on the UCSF pulmonary consult service.

    My research relates to the early detection and prevention of lung cancer. I am interested in the application of computational medicine to tailor chemopreventive and therapeutic strategies to individual profiles as well as adopting new diagnostic and screening tools.

    In order to schedule an appointment with Dr Gesthalter at the UCSF Interventional Pulmonary clinic please call (415)353-7285. Please bring all available images (cat scans, PET scans) on CDs at the time of consultation to facilitate care.

    Clinical Expertise
    • Thoracic malignancies
    • Lung nodules
    • Symptom management
    • Diagnostic and staging procedures
    • Complex pleural effusions – ultrasound, thoracentesis, chest tubes, tunneled pleural catheters, medical thoracoscopy
    • Ablative bronchoscopic techniques (cryo- surgery, electrosurgery, argon plasma coagulation (APC), cryospray, photodynamic therapy)
    • Advanced bronchoscopy (electromagnetic navigation bronchoscopy (EMN), endobronchial ultrasound (EBUS), rigid bronchoscopy)
    • Fiducial placement for radiation therapy
    • Sarcoidosis and other non-malignant lung pathologies
    • Tracheal and bronchial obstructions
    • Tracheal and bronchial stent placement

    Research Interests
    • Lung cancer diagnostics
    • Bioinformatics
    • Application of minimally invasive diagnostic and therapeutic techniques
    • Lung cancer screening
    • Smoking cessation

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 Aug 07. Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576.
      View in: PubMed   Mentions:    Fields:    
    2. AABIP Evidence-Informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters. J Bronchology Interv Pulmonol. 2020 Jul 28. Miller CRJ, Chrissian AA, Lee YCG, Rahman NM, Wahidi MM, Tremblay A, Hsia DW, Almeida FA, Shojaee S. PMID: 32804745.
      View in: PubMed   Mentions:    Fields:    
    3. Flexible Bronchoscopic Deployment of a Silicone Bronchial Stent. J Bronchology Interv Pulmonol. 2020 Jan; 27(1):e10-e12. Gesthalter YB, Seeley EJ. PMID: 31856015.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv. 2019 12; 5(12):eaaw3413. Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, Campbell JD, Beane J. PMID: 31844660.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Indwelling Tunneled Pleural Catheters. Am J Respir Crit Care Med. 2019 12 01; 200(11):P20-P21. Kheir F, Akulian J, Gesthalter YB. PMID: 31774312.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Cryoprobe retrieval of an airway foreign body: A case report and literature review. Int J Pediatr Otorhinolaryngol. 2019 Oct; 125:79-81. David AP, Xu MJ, Rosbe KW, Meyer AK, Gesthalter YB, Chan DK. PMID: 31271971.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Pulmonary Sclerosing Pneumocytoma. J Bronchology Interv Pulmonol. 2018 10; 25(4):e54-e56. Rivera E, Gesthalter Y, VanderLaan P, Parikh MS. PMID: 30247298.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Treatment of persistent bronchopleural fistula with a manually modified endobronchial stent: a case-report and brief literature review. J Thorac Dis. 2018 Oct; 10(10):5960-5963. de Lima A, Holden V, Gesthalter Y, Kent MS, Parikh M, Majid A, Chee A. PMID: 30505507.
      View in: PubMed   Mentions:
    9. Bronchoscopic Management of Endobronchial Tumor in Patient With Hemoptysis and Acute Myocardial Infarction. J Bronchology Interv Pulmonol. 2018 07; 25(3):e37-e39. Perez C, Kheir F, Barry M, Gesthalther Y, Majid A. PMID: 29944595.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Impact of acute exposure to cigarette smoke on airway gene expression. Physiol Genomics. 2018 09 01; 50(9):705-713. Billatos E, Faiz A, Gesthalter Y, LeClerc A, Alekseyev YO, Xiao X, Liu G, Ten Hacken NHT, Heijink IH, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. PMID: 29932825.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Sarcoidosis With Pleural Effusion as the Presenting Symptom. J Bronchology Interv Pulmonol. 2018 Apr; 25(2):148-151. Rivera E, Gesthalter Y, Vardelaan P, Chee A, Majid A. PMID: 29346252.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Evaluations of Implementation at Early-Adopting Lung Cancer Screening Programs: Lessons Learned. Chest. 2017 07; 152(1):70-80. Gesthalter YB, Koppelman E, Bolton R, Slatore CG, Yoon SH, Cain HC, Tanner NT, Au DH, Clark JA, Wiener RS. PMID: 28223153.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016 Dec; 9(12):906-914. Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild A, Lenburg ME, Ionescu DN, Mayo J, Yi JE, Tazelaar H, Harmsen WS, Smith J, Spira AE, Beane J, Limburg PJ, Szabo E. PMID: 27658890.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    14. A Call to Formalize Training in Tobacco Dependence Treatment for Pulmonologists. Ann Am Thorac Soc. 2016 Apr; 13(4):460-1. Gesthalter YB, Wiener RS, Kathuria H. PMID: 27058182.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Translating the transcriptome into tools for the early detection and prevention of lung cancer. Thorax. 2015 May; 70(5):476-81. Gesthalter YB, Vick J, Steiling K, Spira A. PMID: 25628310.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Updates and controversies in the rapidly evolving field of lung cancer screening, early detection, and chemoprevention. Cancers (Basel). 2014 May 16; 6(2):1157-79. Kathuria H, Gesthalter Y, Spira A, Brody JS, Steiling K. PMID: 24840047.
      View in: PubMed   Mentions:
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