Kaveh Ashrafi, PhD
|
Title(s) | Professor, Physiology |
---|
School | School of Medicine |
---|
Address | 600 16th St San Francisco CA 94158
|
---|
Phone | 415-514-4103 |
---|
vCard | Download vCard |
---|
|
|
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
-
Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter. Genes Dev. 2020 Aug 01; 34(15-16):1033-1038.
Lin L, Lemieux GA, Enogieru OJ, Giacomini KM, Ashrafi K. PMID: 32675325.
View in: PubMed Mentions: Fields:
-
Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity. Nat Chem Biol. 2020 10; 16(10):1087-1095.
Chen WW, Lemieux GA, Camp CH, Chang TC, Ashrafi K, Cicerone MT. PMID: 32572275.
View in: PubMed Mentions: 1 Fields: Translation: Animals
-
Intestinal peroxisomal fatty acid ß-oxidation regulates neural serotonin signaling through a feedback mechanism. PLoS Biol. 2019 12; 17(12):e3000242.
Bouagnon AD, Lin L, Srivastava S, Liu CC, Panda O, Schroeder FC, Srinivasan S, Ashrafi K. PMID: 31805041.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
-
Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response. PLoS Genet. 2019 08; 15(8):e1008295.
Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW. PMID: 31398187.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
-
Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport. Hum Mol Genet. 2019 05 01; 28(9):1498-1514.
Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, Ashrafi K, Mandelkow EM, Encalada SE, Kao AW. PMID: 30590647.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
-
The mTOR Target S6 Kinase Arrests Development in Caenorhabditis elegans When the Heat-Shock Transcription Factor Is Impaired. Genetics. 2018 11; 210(3):999-1009.
Chisnell P, Parenteau TR, Tank E, Ashrafi K, Kenyon C. PMID: 30228197.
View in: PubMed Mentions: 1 Fields: Translation: Animals
-
Kynurenic acid accumulation underlies learning and memory impairment associated with aging. Genes Dev. 2018 01 01; 32(1):14-19.
Vohra M, Lemieux GA, Lin L, Ashrafi K. PMID: 29386332.
View in: PubMed Mentions: 2 Fields: Translation: AnimalsCells
-
The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite. PLoS Biol. 2017 Aug; 15(8):e2002032.
Vohra M, Lemieux GA, Lin L, Ashrafi K. PMID: 28763436.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
-
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005680.
Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. PMID: 28704396.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
-
Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans. Trends Endocrinol Metab. 2016 08; 27(8):586-596.
Lemieux GA, Ashrafi K. PMID: 27289335.
View in: PubMed Mentions: 7 Fields: Translation: HumansAnimalsCells
-
Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling. PLoS Genet. 2015 Nov; 11(11):e1005627.
Yee LE, Garcia-Gonzalo FR, Bowie RV, Li C, Kennedy JK, Ashrafi K, Blacque OE, Leroux MR, Reiter JF. PMID: 26540106.
View in: PubMed Mentions: 28 Fields: Translation: HumansAnimalsCells
-
Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans. Annu Rev Genet. 2015; 49:413-38.
Lemieux GA, Ashrafi K. PMID: 26473379.
View in: PubMed Mentions: 14 Fields: Translation: AnimalsCells
-
Stressing about misplaced fat is a key to longevity. Elife. 2015 Aug 19; 4.
Lemieux GA, Ashrafi K. PMID: 26287524.
View in: PubMed Mentions: 1 Fields: Translation: AnimalsCells
-
Kynurenic acid is a nutritional cue that enables behavioral plasticity. Cell. 2015 Jan 15; 160(1-2):119-31.
Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. PMID: 25594177.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
-
Insights and challenges in using C. elegans for investigation of fat metabolism. Crit Rev Biochem Mol Biol. 2015 Jan-Feb; 50(1):69-84.
Lemieux GA, Ashrafi K. PMID: 25228063.
View in: PubMed Mentions: 9 Fields: Translation: Animals
-
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad Sci U S A. 2014 Jul 08; 111(27):9983-8.
Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM. PMID: 24961373.
View in: PubMed Mentions: 63 Fields: Translation: AnimalsCells
-
Loss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretions. PLoS Genet. 2014 Jun; 10(6):e1004394.
Cunningham KA, Bouagnon AD, Barros AG, Lin L, Malard L, Romano-Silva MA, Ashrafi K. PMID: 24921650.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
-
Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses. PLoS One. 2014; 9(3):e92552.
Ward JD, Mullaney B, Schiller BJ, He LD, Petnic SE, Couillault C, Pujol N, Bernal TU, Van Gilst MR, Ashrafi K, Ewbank JJ, Yamamoto KR. PMID: 24651852.
View in: PubMed Mentions: 11 Fields: Translation: AnimalsCells
-
Dopamine signaling regulates fat content through ß-oxidation in Caenorhabditis elegans. PLoS One. 2014; 9(1):e85874.
Barros AG, Bridi JC, de Souza BR, de Castro Júnior C, de Lima Torres KC, Malard L, Jorio A, de Miranda DM, Ashrafi K, Romano-Silva MA. PMID: 24465759.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
-
Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development. PLoS Genet. 2013; 9(12):e1003992.
Ward JD, Bojanala N, Bernal T, Ashrafi K, Asahina M, Yamamoto KR. PMID: 24348269.
View in: PubMed Mentions: 12 Fields: Translation: AnimalsCells
-
In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding. PLoS Biol. 2013 Nov; 11(11):e1001712.
Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K. PMID: 24260022.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimals
-
Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation. Aging Cell. 2013 Oct; 12(5):932-40.
Chen AT, Guo C, Dumas KJ, Ashrafi K, Hu PJ. PMID: 23786484.
View in: PubMed Mentions: 16 Fields: Translation: AnimalsCells
-
AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans. Cell Metab. 2012 Jul 03; 16(1):113-21.
Cunningham KA, Hua Z, Srinivasan S, Liu J, Lee BH, Edwards RH, Ashrafi K. PMID: 22768843.
View in: PubMed Mentions: 26 Fields: Translation: AnimalsCells
-
Analyses of C. elegans fat metabolic pathways. Methods Cell Biol. 2012; 107:383-407.
Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K. PMID: 22226531.
View in: PubMed Mentions: 15 Fields: Translation: Animals
-
Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. elegans Bardet-Biedl syndrome mutants. PLoS Biol. 2011 Dec; 9(12):e1001219.
Lee BH, Liu J, Wong D, Srinivasan S, Ashrafi K. PMID: 22180729.
View in: PubMed Mentions: 19 Fields: Translation: AnimalsCells
-
A whole-organism screen identifies new regulators of fat storage. Nat Chem Biol. 2011 Apr; 7(4):206-13.
Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z. PMID: 21390037.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
-
A stress-responsive system for mitochondrial protein degradation. Mol Cell. 2010 Nov 12; 40(3):465-80.
Heo JM, Livnat-Levanon N, Taylor EB, Jones KT, Dephoure N, Ring J, Xie J, Brodsky JL, Madeo F, Gygi SP, Ashrafi K, Glickman MH, Rutter J. PMID: 21070972.
View in: PubMed Mentions: 110 Fields: Translation: HumansAnimalsCells
-
Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25. Cell Metab. 2010 Oct 06; 12(4):398-410.
Mullaney BC, Blind RD, Lemieux GA, Perez CL, Elle IC, Faergeman NJ, Van Gilst MR, Ingraham HA, Ashrafi K. PMID: 20889131.
View in: PubMed Mentions: 28 Fields: Translation: Animals
-
mTOR complex-2 activates ENaC by phosphorylating SGK1. J Am Soc Nephrol. 2010 May; 21(5):811-8.
Lu M, Wang J, Jones KT, Ives HE, Feldman ME, Yao LJ, Shokat KM, Ashrafi K, Pearce D. PMID: 20338997.
View in: PubMed Mentions: 36 Fields: Translation: HumansCells
-
Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis Model Mech. 2009 May-Jun; 2(5-6):224-9.
Jones KT, Ashrafi K. PMID: 19407330.
View in: PubMed Mentions: 27 Fields: Translation: Animals
-
Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1. PLoS Biol. 2009 Mar 03; 7(3):e60.
Jones KT, Greer ER, Pearce D, Ashrafi K. PMID: 19260765.
View in: PubMed Mentions: 80 Fields: Translation: Animals
-
Fat rationing in dauer times. Cell Metab. 2009 Feb; 9(2):113-4.
Cunningham KA, Ashrafi K. PMID: 19187769.
View in: PubMed Mentions: 4 Fields: Translation: Animals
-
C. elegans fat storage and metabolic regulation. Biochim Biophys Acta. 2009 Jun; 1791(6):474-8.
Mullaney BC, Ashrafi K. PMID: 19168149.
View in: PubMed Mentions: 40 Fields: Translation: Animals
-
A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan. PLoS Genet. 2008 Oct; 4(10):e1000213.
Lee BH, Ashrafi K. PMID: 18846209.
View in: PubMed Mentions: 44 Fields: Translation: AnimalsCells
-
Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metab. 2008 Aug; 8(2):118-31.
Greer ER, Pérez CL, Van Gilst MR, Lee BH, Ashrafi K. PMID: 18680713.
View in: PubMed Mentions: 87 Fields: Translation: AnimalsCells
-
Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell Metab. 2008 Jun; 7(6):533-44.
Srinivasan S, Sadegh L, Elle IC, Christensen AG, Faergeman NJ, Ashrafi K. PMID: 18522834.
View in: PubMed Mentions: 81 Fields: Translation: Animals
-
Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry. J Neurochem. 2007 Jul; 102(1):246-60.
Husson SJ, Janssen T, Baggerman G, Bogert B, Kahn-Kirby AH, Ashrafi K, Schoofs L. PMID: 17564681.
View in: PubMed Mentions: 40 Fields: Translation: Animals
-
Obesity and the regulation of fat metabolism. WormBook. 2007 Mar 09; 1-20.
Ashrafi K. PMID: 18050496.
View in: PubMed Mentions: 56 Fields: Translation: HumansAnimals
-
Mapping out starvation responses. Cell Metab. 2006 Apr; 3(4):235-6.
Ashrafi K. PMID: 16581000.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature. 2003 Jan 16; 421(6920):268-72.
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. PMID: 12529643.
View in: PubMed Mentions: 317 Fields: Translation: HumansAnimalsCells
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
---|
2003 | 1 | 2006 | 1 | 2007 | 2 | 2008 | 3 | 2009 | 4 | 2010 | 3 | 2011 | 2 | 2012 | 2 | 2013 | 3 | 2014 | 5 | 2015 | 4 | 2016 | 1 | 2017 | 2 | 2018 | 2 | 2019 | 3 | 2020 | 2 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
newest
oldest
line numbers
double spacing
all authors
publication IDs
|
Derived automatically from this person's publications.
_
People in Profiles who have published with this person.
_
People who share similar concepts with this person.
_
Search Department
_
|