Dr. Kato-Maeda’s research activities focuses on 1) transmission of Mycobacterium tuberculosis (MTB) and 2) drug- resistant tuberculosis. Dr. Kato-Maeda, along with my domestic and international collaborators, established community-based studies in San Francisco, Tanzania, and Uganda to study the transmission dynamics of MTB to identify factors that can be modified to decrease transmission of MTB, and to identify populations that have a high risk of infection. Another goal of Dr. Kato-Maeda’s research is to determine the impact of bacterial characteristics on the transmission dynamics of MTB. Recently she and her colleagues created and published a collection of well-characterized clinical MTB strains representing different lineages which will be used by the global TB research community in in vitro and in animal studies.
Dr. Kato-Maeda is also interested in identifying novel genomic factors that govern drug-resistant tuberculosis to enable more accurate real-time PCR, line probe assays and sequencing-based methods for rapid identification of drug-resistant TB.
She has collaborations with the San Francisco Department of Public Health Division of Tuberculosis, CDC, and other academic institutions in United States and abroad including Tanzania, Uganda and the Philippines.
Dr. Kato-Maeda participates in teaching activities related to the molecular epidemiology of tuberculosis as well as research management involving laboratory components. She also facilitates laboratory meetings for the tuberculosis research community at ZSFG/UCSF. Dr. Kato-Maeda also serves as a consultant for laboratory aspects of the Tuberculosis Control Program, and is a consultant to numerous research projects related to tuberculosis.