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Susan Lynch, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, MSB
San Francisco CA 94117
Phone415-476-6784
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    Collapse Biography 
    Collapse Education and Training
    University College Dublin, IrelandPhD2000Mircobiology
    University College Dublin, IrelandBS1995Microbiology/Biostatistics
    Collapse Awards and Honors
    American Society of Microbiology2017  - 2019Distinguished Lecturer
    Foreign Policy Magazine2016  - 2016Global Thinker
    American Association for Allergy Asthma and Immunology2015  - 2015Rebecca Buckley Lectureship
    International Innovationns2014  - 2014Women in Healthcare
    2013  - 2013Irish Health and Science 100 award

    Collapse Overview 
    Collapse Overview
    Our human microbiome research program focuses on the gastrointestinal and airway microbiomes and their influence on the development and maintenance of chronic inflammatory disease. We study the early-life origins of chronic inflammatory disease and have demonstrated a role for the neonatal gut microbiome and its metabolic products as a predictor of allergic asthma development in childhood. We are also interested in established inflammatory conditions and have shown that distinct microbiota exist in adults with IBD, chronic sinusitus or HIV-infection, which relate to immunologically and pathologically distinct disease endotypes. Our group has pioneered the application of newly developed statistical approaches to the multi-dimensional microbiome data sets developed by next generation sequencing approaches. We have developed and made publicly available custom scripts and novel tools to facilitate such analyses. In addition, we have developed novel ex vivo assays to assess the capacity of human microbiota, specific microbial species or their products to elicit host immune responses ex vivo, providing an objective assessment of their immunomodulatory capacity. I founded and direct the Microbiome Research Core, and am the Associate Director of the Microbiome in Inflammatory Bowel Disease Research Program at UCSF. I have also co-founded and serve as a board member of Siolta Therapeutics, a start-up company at QB3 that focuses on translating our bench-based human microbiome findings into effective therapeutics for prevention or treatment of immune disorders.

    Collapse Research 
    Collapse Research Activities and Funding
    Binational Early Asthma & Microbiome Study (BEAMS)
    NIH/NIAID P01AI148104Jul 10, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Integrated Analysis of Microbial and Genomic data in Obstructive Lung Disease (I AM GOLD) Study
    NIH/NHLBI R01HL143998Sep 15, 2019 - Jul 31, 2023
    Role: Co-Principal Investigator
    Interactions between Environmental Microbiome, Maternal Immunity, Neonatal Epigenome and Respiratory Microbiome Development as Determinants of Asthma In Childhood
    NIH/NIAID R21AI133765Aug 15, 2017 - Jul 31, 2019
    Role: Co-Principal Investigator
    Inner City Asthma Consortium (ICAC): Immunologic Approaches to Reduce Asthma (University of Wisconsin System)
    NIH/NIAID AI114271Sep 1, 2016 - Aug 31, 2023
    Role: UCSF PI
    Children’s Respiratory Research and the Environment Workgroup (CREW).
    NIH/NIAID PO515267Sep 1, 2016 - Aug 31, 2023
    Role: UCSF PI
    Delivery mode, environment and the gut microbiome: influence on childhood body size
    NIH/NICHD R01 DH082147Sep 1, 2015 - Aug 31, 2020
    Role: Co-I
    Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use
    NIH/NIDA R01DA040532Aug 1, 2015 - May 31, 2020
    Role: Co-I
    Fecal microbial transplantation to reduce HIV-associated inflammation.
    NIH/NIDDK R21DK104664Jul 1, 2015 - Jun 30, 2017
    Role: Co-I
    Fungal microbiome of the house environment and its relationship to human microbiome composition
    Sloan Foundation Jun 1, 2013 - May 31, 2016
    Pets and the Infant Microbiome: Effect on Immune Maturation & Atopic Asthma
    NIH P01AI089473Jul 6, 2012 - Jun 30, 2017
    Role: Co-Investigator
    Gut and Airway Microbiome in Allergy and Asthma: Relationships to Immune and Clinical Phenotype. Effects of Inhaled Corticosteroid Treatment
    NIAID Jul 1, 2012 - Jun 30, 2015
    Role: Co-Investigator
    Role of the human microbiome in inflammatory bowel disease amongst migrant South Asian populations.
    Broad Foundation IBD-0327R-2May 1, 2012 - Apr 30, 2015
    Cigarette Smoke Exposure and Acute Lung Injury After Severe Blunt Trauma
    NIH/NHLBI R01HL110969Dec 15, 2011 - Nov 30, 2016
    Role: Co-Investigator
    Sinusitis in Children and the Nasopharyngeal Microbiome
    NIH R01AI097172Dec 1, 2011 - Nov 30, 2016
    Role: Co-Investigator
    Relationships between gut microbiota and immunity in the liver.
    UCSF Liver Center Pilot and Feasibility award May 1, 2011 - Apr 30, 2012
    Role: Co-Investigator
    Lung Microbiome in Cohorts of HIV-Infected Persons (Lung MicroCHIP) Study.
    NIH/NHLBI 1U01HL098964Oct 1, 2009 - Oct 1, 2015
    Probiotic Outcomes of Enteric Microflora (POEM) Study
    NIH/NCCAM R21AT004732Oct 1, 2009 - Sep 30, 2011
    Role: Co-Investigator
    Effect of Probiotics on CF Bacterial Communities.
    CFF Sep 1, 2009 - Aug 31, 2013
    Role: Co-Investigator
    Heterogeneity among human CD4 T lymphocytes.
    NIH/NIAID AI-026322-18A2Jul 1, 2009 - Jun 30, 2011
    Role: Co-Investigator
    The human microbiome in pediatric abdominal pain and Intestinal Inflammation.
    NIH/NIDDK 1UH2DK083990-01Apr 1, 2009 - Mar 31, 2013
    Role: Co-Investigator
    NKT cells recognize and respond to microbes at mucosal surfaces
    NIH/NIAID AI083523-01Mar 1, 2009 - Feb 28, 2011
    Role: Co-Investigator
    S100 protein potentiation of Pseudomonas aeruginosa in cystic fibrosis
    Resource Allocation Project Award, University of California San Francisco Oct 1, 2008 - Sep 30, 2010
    Probiotic Improvement of Genitourinary and Gastrointestinal Health in Girls with Spina Bifida.
    Spina Bifida Association Sep 1, 2008 - Aug 30, 2009
    Role Description: Young Investigator Award
    Microarray Analysis of Chronic Rhinosinusitis
    American Rhinological Society Jul 1, 2008 - Jun 30, 2009
    Role of PAI-1 in lung injury induced by P. aeruginosa
    UCSF REAC Award Mar 1, 2008 - Feb 28, 2009
    Resequencing microarray for rapid detection &antimicrobial resistance profiling
    NIH/NIAID U01AI075410Aug 1, 2007 - Jul 31, 2013
    Role: Principal Investigator
    Analysis of bacterial community dynamics in adult patients with exacerbations of Chronic Obstructive Pulmonary Disease
    American Lung Association Jul 1, 2007 - Jun 30, 2009
    Anti-PcrV against P. aeruginosa in CF
    Cystic Fibrosis Foundation Sep 1, 2006 - Aug 31, 2008
    Role: Co-Investigator
    Quantitative Search for Microbes in Bronchial Biopsies from Asthmatic and Healthy Subjects
    NIH/NHLBI HL074207Aug 1, 2006 - Jul 31, 2009
    16S Ancillary Study MIA Supplement
    NIH/NHLBI U10 HL074207Aug 1, 2006 - Jul 31, 2007
    Role: Co-Investigator
    Effect of quorum sensing inhibiting furanones on clinically relevant isolates of pseudomonas aeruginosa
    UCSF Academic Committee on Research Feb 8, 2006 - Mar 1, 2007
    Use of anti-PcrV IgG against P. aeruginosa in Cystic Fibrosis
    CFRDP Jan 9, 2006 - Jan 8, 2007
    Role: Co-Investigator
    The role of infection in asthma pathogenesis
    Sandler Asthma Basic Research Center Jan 1, 2006 - Dec 31, 2007
    Role: Co-Investigator
    Expression and pathogenicity of Pseudomonas aeruginosa The goal of this study is to examine virulence systems and evolution of resistance of P. aeruginosa clinical isolates.
    NIH/NHLBI HL69809Dec 11, 2003 - Nov 30, 2008
    Role: Co-Investigator
    Gene Expression and Pathogenicity of P.aeruginosa
    NIH/NHLBI R01HL069809Dec 11, 2003 - Nov 30, 2008
    Role: Principal Investigator
    Project 2: Mechanisms of Bacterial Induced Lung Injury
    NIH/NHLBI P50 HL074005Dec 1, 2003 - Jun 30, 2008
    Role: Co-Investigator
    Dean's Fellowship
    Stanford University School of Medicine Aug 1, 2002 - Aug 1, 2003
    Postdoctoral Fellowship
    Enterprise Ireland Aug 1, 2001 - Aug 1, 2002
    Research Award
    Enterprise Ireland Basic Aug 1, 1995 - Aug 1, 1998

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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Association between cesarean delivery types and obesity in preadolescence. Int J Obes (Lond). 2020 Sep 01. Sitarik AR, Havstad SL, Johnson CC, Jones K, Levin AM, Lynch SV, Ownby DR, Rundle AG, Straughen JK, Wegienka G, Woodcroft KJ, Yong GJM, Cassidy-Bushrow AE. PMID: 32873910.
      View in: PubMed   Mentions:    Fields:    
    2. Fetal and early postnatal lead exposure measured in teeth associates with infant gut microbiota. Environ Int. 2020 Aug 29; 144:106062. Sitarik AR, Arora M, Austin C, Bielak LF, Eggers S, Johnson CC, Lynch SV, Kyun Park S, Hank Wu KH, Yong GJM, Cassidy-Bushrow AE. PMID: 32871381.
      View in: PubMed   Mentions:    Fields:    
    3. Distinct associations of sputum and oral microbiota with atopic, immunologic, and clinical features in mild asthma. J Allergy Clin Immunol. 2020 Apr 13. Durack J, Christian LS, Nariya S, Gonzalez J, Bhakta NR, Ansel KM, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Peters SP, Rosenberg SR, Sorkness CA, Wechsler ME, Wenzel SE, White SR, Lynch SV, Boushey HA, Huang YJ. PMID: 32298699.
      View in: PubMed   Mentions:    Fields:    
    4. Author Correction: Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance. Nat Microbiol. 2019 Nov; 4(11):2020. Levan SR, Stamnes KA, Lin DL, Panzer AR, Fukui E, McCauley K, Fujimura KE, McKean M, Ownby DR, Zoratti EM, Boushey HA, Cabana MD, Johnson CC, Lynch SV. PMID: 31492948.
      View in: PubMed   Mentions:    Fields:    
    5. Translating the gut microbiome: ready for the clinic? Nat Rev Gastroenterol Hepatol. 2019 11; 16(11):656-661. Lynch SV, Ng SC, Shanahan F, Tilg H. PMID: 31562390.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance. Nat Microbiol. 2019 11; 4(11):1851-1861. Levan SR, Stamnes KA, Lin DL, Panzer AR, Fukui E, McCauley K, Fujimura KE, McKean M, Ownby DR, Zoratti EM, Boushey HA, Cabana MD, Johnson CC, Lynch SV. PMID: 31332384.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    7. Fecal Microbiota Transplantation in Pouchitis: Clinical, Endoscopic, Histologic, and Microbiota Results from a Pilot Study. Dig Dis Sci. 2020 04; 65(4):1099-1106. Selvig D, Piceno Y, Terdiman J, Zydek M, Umetsu SE, Balitzer D, Fadrosh D, Lynch K, Lamere B, Leith T, Kassam Z, Beck K, Lewin S, Ma A, Somsouk M, Lynch SV, El-Nachef N. PMID: 31302808.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. A20 in dendritic cells restrains intestinal anti-bacterial peptide expression and preserves commensal homeostasis. PLoS One. 2019; 14(7):e0218999. Talpin A, Kattah MG, Advincula R, Fadrosh D, Lynch K, LaMere B, Fujimura KE, Nagalingam NA, Malynn BA, Lynch SV, Ma A. PMID: 31295268.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Author Correction: Differences in the fecal microbiota of neonates born at home or in the hospital. Sci Rep. 2019 Jun 18; 9(1):9044. Combellick JL, Shin H, Shin D, Cai Y, Hagan H, Lacher C, Lin DL, McCauley K, Lynch SV, Dominguez-Bello MG. PMID: 31209226.
      View in: PubMed   Mentions:    Fields:    
    10. Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma. J Allergy Clin Immunol. 2019 11; 144(5):1187-1197. McCauley K, Durack J, Valladares R, Fadrosh DW, Lin DL, Calatroni A, LeBeau PK, Tran HT, Fujimura KE, LaMere B, Merana G, Lynch K, Cohen RT, Pongracic J, Khurana Hershey GK, Kercsmar CM, Gill M, Liu AH, Kim H, Kattan M, Teach SJ, Togias A, Boushey HA, Gern JE, Jackson DJ, Lynch SV. PMID: 31201890.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    11. Community ecology as a framework for human microbiome research. Nat Med. 2019 06; 25(6):884-889. Gilbert JA, Lynch SV. PMID: 31133693.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Fecal microbiota transplant for Crohn disease: A study evaluating safety, efficacy, and microbiome profile. United European Gastroenterol J. 2019 07; 7(6):807-814. Gutin L, Piceno Y, Fadrosh D, Lynch K, Zydek M, Kassam Z, LaMere B, Terdiman J, Ma A, Somsouk M, Lynch S, El-Nachef N. PMID: 31316785.
      View in: PubMed   Mentions:
    13. Gut microbiota in HIV-pneumonia patients is related to peripheral CD4 counts, lung microbiota, and in vitro macrophage dysfunction. Microbiome. 2019 03 11; 7(1):37. Shenoy MK, Fadrosh DW, Lin DL, Worodria W, Byanyima P, Musisi E, Kaswabuli S, Zawedde J, Sanyu I, Chang E, Fong S, McCauley K, Davis JL, Huang L, Lynch SV. PMID: 30857553.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Enteric Virome and Bacterial Microbiota in Children With Ulcerative Colitis and Crohn Disease. J Pediatr Gastroenterol Nutr. 2019 01; 68(1):30-36. Fernandes MA, Verstraete SG, Phan TG, Deng X, Stekol E, LaMere B, Lynch SV, Heyman MB, Delwart E. PMID: 30169455.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    15. Longitudinal Phenotypes of Respiratory Health in a High-Risk Urban Birth Cohort. Am J Respir Crit Care Med. 2019 01 01; 199(1):71-82. Bacharier LB, Beigelman A, Calatroni A, Jackson DJ, Gergen PJ, O'Connor GT, Kattan M, Wood RA, Sandel MT, Lynch SV, Fujimura KE, Fadrosh DW, Santee CA, Boushey H, Visness CM, Gern JE. PMID: 30079758.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    16. Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2019 Jan; 3(1):29-43. Sharpton SR, Yong GJM, Terrault NA, Lynch SV. PMID: 30619992.
      View in: PubMed   Mentions:
    17. Rules of engagement in the gut microbiome. Nat Med. 2018 11; 24(11):1642-1644. Rackaityte E, Lynch SV. PMID: 30401869.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    18. Differences in the fecal microbiota of neonates born at home or in the hospital. Sci Rep. 2018 10 23; 8(1):15660. Combellick JL, Shin H, Shin D, Cai Y, Hagan H, Lacher C, Lin DL, McCauley K, Lynch SV, Dominguez-Bello MG. PMID: 30353125.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. The gut microbiome: Relationships with disease and opportunities for therapy. J Exp Med. 2019 01 07; 216(1):20-40. Durack J, Lynch SV. PMID: 30322864.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    20. Motility and biofilm formation of the emerging gastrointestinal pathogen Campylobacter concisus differs under microaerophilic and anaerobic environments. Gut Microbes. 2019; 10(1):34-44. Ovesen S, Durack J, Kirk KF, Nielsen HL, Nielsen H, Lynch SV. PMID: 30252590.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization. Microbiome. 2018 09 05; 6(1):154. Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W. PMID: 30185226.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    22. Bacterial biogeography of adult airways in atopic asthma. Microbiome. 2018 06 09; 6(1):104. Durack J, Huang YJ, Nariya S, Christian LS, Ansel KM, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, King TS, White SR, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Peters SP, Smith LJ, Wechsler ME, Lynch SV, Boushey HA. PMID: 29885665.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    23. Heterogeneity of Microbiota Dysbiosis in Chronic Rhinosinusitis: Potential Clinical Implications and Microbial Community Mechanisms Contributing to Sinonasal Inflammation. Front Cell Infect Microbiol. 2018; 8:168. Lee K, Pletcher SD, Lynch SV, Goldberg AN, Cope EK. PMID: 29876323.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    24. Current understanding of the human microbiome. Nat Med. 2018 04 10; 24(4):392-400. Gilbert JA, Blaser MJ, Caporaso JG, Jansson JK, Lynch SV, Knight R. PMID: 29634682.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    25. Dynamics of Bacterial Colonization With Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis During Symptomatic and Asymptomatic Viral Upper Respiratory Tract Infection. Clin Infect Dis. 2018 03 19; 66(7):1045-1053. DeMuri GP, Gern JE, Eickhoff JC, Lynch SV, Wald ER. PMID: 29121208.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 03 01; 197(5):621-631. Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. PMID: 29035085.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    27. Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation. Nat Commun. 2018 02 16; 9(1):707. Durack J, Kimes NE, Lin DL, Rauch M, McKean M, McCauley K, Panzer AR, Mar JS, Cabana MD, Lynch SV. PMID: 29453431.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    28. Role of the lung microbiome in HIV pathogenesis. Curr Opin HIV AIDS. 2018 Jan; 13(1):45-52. Shenoy MK, Lynch SV. PMID: 29035946.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    29. Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. Trauma Surg Acute Care Open. 2017; 2(1):e000108. Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ. PMID: 29766103.
      View in: PubMed   Mentions:
    30. Early-life home environment and risk of asthma among inner-city children. J Allergy Clin Immunol. 2018 04; 141(4):1468-1475. O'Connor GT, Lynch SV, Bloomberg GR, Kattan M, Wood RA, Gergen PJ, Jaffee KF, Calatroni A, Bacharier LB, Beigelman A, Sandel MT, Johnson CC, Faruqi A, Santee C, Fujimura KE, Fadrosh D, Boushey H, Visness CM, Gern JE. PMID: 28939248.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsPHPublic Health
    31. Breast Milk Transforming Growth Factor ß Is Associated With Neonatal Gut Microbial Composition. J Pediatr Gastroenterol Nutr. 2017 09; 65(3):e60-e67. Sitarik AR, Bobbitt KR, Havstad SL, Fujimura KE, Levin AM, Zoratti EM, Kim H, Woodcroft KJ, Wegienka G, Ownby DR, Joseph CLM, Lynch SV, Johnson CC. PMID: 28827481.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Early Probiotic Supplementation for Eczema and Asthma Prevention: A Randomized Controlled Trial. Pediatrics. 2017 Sep; 140(3). Cabana MD, McKean M, Caughey AB, Fong L, Lynch S, Wong A, Leong R, Boushey HA, Hilton JF. PMID: 28784701.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    33. Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals. Gut Microbes. 2017 09 03; 8(5):440-450. Vujkovic-Cvijin I, Rutishauser RL, Pao M, Hunt PW, Lynch SV, McCune JM, Somsouk M. PMID: 28541799.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences. Microbiome. 2017 05 12; 5(1):53. Cope EK, Goldberg AN, Pletcher SD, Lynch SV. PMID: 28494786.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    35. Promotion of Epithelial Barrier Integrity Via Probiotic-derived Products. J Pediatr Gastroenterol Nutr. 2017 03; 64(3):335-336. Durack J, Lynch SV. PMID: 27472476.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    36. Immune Response and Mortality Risk Relate to Distinct Lung Microbiomes in Patients with HIV and Pneumonia. Am J Respir Crit Care Med. 2017 01 01; 195(1):104-114. Shenoy MK, Iwai S, Lin DL, Worodria W, Ayakaka I, Byanyima P, Kaswabuli S, Fong S, Stone S, Chang E, Davis JL, Faruqi AA, Segal MR, Huang L, Lynch SV. PMID: 27447987.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. The Human Intestinal Microbiome in Health and Disease. N Engl J Med. 2016 Dec 15; 375(24):2369-2379. Lynch SV, Pedersen O. PMID: 27974040.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansAnimals
    38. The Lung Microbiome and Airway Disease. Ann Am Thorac Soc. 2016 12; 13 Suppl 2:S462-S465. Lynch SV. PMID: 28005424.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment. J Allergy Clin Immunol. 2017 Jul; 140(1):63-75. Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ. PMID: 27838347.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    40. Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls. BMC Neurol. 2016 Sep 21; 16(1):182. Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Spencer CM, Lynch SV, Zamvil SS, Waubant E. PMID: 27652609.
      View in: PubMed   Mentions: 21     Fields:    
    41. Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation. Nat Med. 2016 10; 22(10):1187-1191. Fujimura KE, Sitarik AR, Havstad S, Lin DL, Levan S, Fadrosh D, Panzer AR, LaMere B, Rackaityte E, Lukacs NW, Wegienka G, Boushey HA, Ownby DR, Zoratti EM, Levin AM, Johnson CC, Lynch SV. PMID: 27618652.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    42. A chronic rhinosinusitis-derived isolate of Pseudomonas aeruginosa induces acute and pervasive effects on the murine upper airway microbiome and host immune response. Int Forum Allergy Rhinol. 2016 12; 6(12):1229-1237. Cope EK, Goldberg AN, Pletcher SD, Lynch SV. PMID: 27598436.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    43. Joint effects of pregnancy, sociocultural, and environmental factors on early life gut microbiome structure and diversity. Sci Rep. 2016 08 25; 6:31775. Levin AM, Sitarik AR, Havstad SL, Fujimura KE, Wegienka G, Cassidy-Bushrow AE, Kim H, Zoratti EM, Lukacs NW, Boushey HA, Ownby DR, Lynch SV, Johnson CC. PMID: 27558272.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    44. Disease Severity and Immune Activity Relate to Distinct Interkingdom Gut Microbiome States in Ethnically Distinct Ulcerative Colitis Patients. mBio. 2016 08 16; 7(4). Mar JS, LaMere BJ, Lin DL, Levan S, Nazareth M, Mahadevan U, Lynch SV. PMID: 27531910.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    45. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight. 2016 Jul 07; 1(10). Belinson H, Savage AK, Fadrosh D, Kuo YM, Lin D, Valladares R, Nusse Y, Wynshaw-Boris A, Lynch SV, Locksley RM, Klein OD. PMID: 27525310.
      View in: PubMed   Mentions: 5     Fields:    
    46. Airway Microbiota and the Implications of Dysbiosis in Asthma. Curr Allergy Asthma Rep. 2016 07; 16(8):52. Durack J, Boushey HA, Lynch SV. PMID: 27393699.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    47. Nasopharyngeal microbiota composition of children is related to the frequency of upper respiratory infection and acute sinusitis. Microbiome. 2016 07 01; 4(1):34. Santee CA, Nagalingam NA, Faruqi AA, DeMuri GP, Gern JE, Wald ER, Lynch SV. PMID: 27364497.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    48. The microbiome and development of allergic disease. Curr Opin Allergy Clin Immunol. 2016 Apr; 16(2):165-71. Lynch SV, Boushey HA. PMID: 26885707.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsPHPublic Health
    49. Gut Microbiota and Allergic Disease. New Insights. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S51-4. Lynch SV. PMID: 27027953.
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    50. Race-specific Association of Caesarean-Section Delivery with Body Size at Age 2 Years. Ethn Dis. 2016 01 21; 26(1):61-8. Cassidy-Bushrow AE, Wegienka G, Havstad S, Levin AM, Lynch SV, Ownby DR, Rundle AG, Woodcroft KJ, Zoratti EM, Johnson CC. PMID: 26843797.
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    51. Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in Children Ages 4-7 Years. J Pediatr. 2016 Apr; 171:133-9.e1. DeMuri GP, Gern JE, Moyer SC, Lindstrom MJ, Lynch SV, Wald ER. PMID: 26787374.
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    52. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. PMID: 26305520.
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    53. Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1335-44. Beck JM, Schloss PD, Venkataraman A, Twigg H, Jablonski KA, Bushman FD, Campbell TB, Charlson ES, Collman RG, Crothers K, Curtis JL, Drews KL, Flores SC, Fontenot AP, Foulkes MA, Frank I, Ghedin E, Huang L, Lynch SV, Morris A, Palmer BE, Schmidt TM, Sodergren E, Weinstock GM, Young VB. PMID: 26247840.
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    54. Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. Cell Rep. 2015 Nov 24; 13(8):1589-97. Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM. PMID: 26586432.
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    55. The airway microbiome in patients with severe asthma: Associations with disease features and severity. J Allergy Clin Immunol. 2015 Oct; 136(4):874-84. Huang YJ, Nariya S, Harris JM, Lynch SV, Choy DF, Arron JR, Boushey H. PMID: 26220531.
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    56. Influence and effect of the human microbiome in allergy and asthma. Curr Opin Rheumatol. 2015 Jul; 27(4):373-80. Panzer AR, Lynch SV. PMID: 26002029.
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    57. Does pet-keeping modify the association of delivery mode with offspring body size? Matern Child Health J. 2015 Jun; 19(6):1426-33. Cassidy-Bushrow AE, Wegienka G, Havstad S, Levin AM, Lynch SV, Ownby DR, Rundle AG, Woodcroft KJ, Zoratti EM, Johnson CC. PMID: 25427878.
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    58. Microbiota in allergy and asthma and the emerging relationship with the gut microbiome. Cell Host Microbe. 2015 May 13; 17(5):592-602. Fujimura KE, Lynch SV. PMID: 25974301.
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    59. Use of 16S rRNA gene for identification of a broad range of clinically relevant bacterial pathogens. PLoS One. 2015; 10(2):e0117617. Srinivasan R, Karaoz U, Volegova M, MacKichan J, Kato-Maeda M, Miller S, Nadarajan R, Brodie EL, Lynch SV. PMID: 25658760.
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    60. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Pediatric Patients: Encouragement Wrapped in Caution. J Pediatr Gastroenterol Nutr. 2015 Jan; 60(1):1-3. Lynch SV. PMID: 25546336.
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    61. Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems. Sci Transl Med. 2014 Sep 03; 6(252):252ra120. Ardeshir A, Narayan NR, Méndez-Lagares G, Lu D, Rauch M, Huang Y, Van Rompay KK, Lynch SV, Hartigan-O'Connor DJ. PMID: 25186175.
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    62. Fecal microbial therapy: promises and pitfalls. J Pediatr Gastroenterol Nutr. 2014 Aug; 59(2):157-61. Merenstein D, El-Nachef N, Lynch SV. PMID: 24796803.
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    63. Amelioration of DSS-induced murine colitis by VSL#3 supplementation is primarily associated with changes in ileal microbiota composition. Gut Microbes. 2014 Jul 01; 5(4):494-503. Mar JS, Nagalingam NA, Song Y, Onizawa M, Lee JW, Lynch SV. PMID: 25144681.
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    64. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014 Sep; 134(3):593-601.e12. Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, O'Connor GT, Sandel MT, Calatroni A, Matsui E, Johnson CC, Lynn H, Visness CM, Jaffee KF, Gergen PJ, Gold DR, Wright RJ, Fujimura K, Rauch M, Busse WW, Gern JE. PMID: 24908147.
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    65. Airway microbiome dynamics in exacerbations of chronic obstructive pulmonary disease. J Clin Microbiol. 2014 Aug; 52(8):2813-23. Huang YJ, Sethi S, Murphy T, Nariya S, Boushey HA, Lynch SV. PMID: 24850358.
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    66. The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients. PLoS One. 2014; 9(4):e95726. Iwai S, Huang D, Fong S, Jarlsberg LG, Worodria W, Yoo S, Cattamanchi A, Davis JL, Kaswabuli S, Segal M, Huang L, Lynch SV. PMID: 24752365.
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    67. Viruses and microbiome alterations. Ann Am Thorac Soc. 2014 Jan; 11 Suppl 1:S57-60. Lynch SV. PMID: 24437408.
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    68. House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):805-10. Fujimura KE, Demoor T, Rauch M, Faruqi AA, Jang S, Johnson CC, Boushey HA, Zoratti E, Ownby D, Lukacs NW, Lynch SV. PMID: 24344318.
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    69. Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism. Sci Transl Med. 2013 Jul 10; 5(193):193ra91. Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM. PMID: 23843452.
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    70. Probiotic strategies for treatment of respiratory diseases. Trends Microbiol. 2013 Sep; 21(9):485-92. Nagalingam NA, Cope EK, Lynch SV. PMID: 23707554.
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    71. Comparison of the respiratory microbiome in healthy nonsmokers and smokers. Am J Respir Crit Care Med. 2013 May 15; 187(10):1067-75. Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, Flores SC, Fontenot AP, Ghedin E, Huang L, Jablonski K, Kleerup E, Lynch SV, Sodergren E, Twigg H, Young VB, Bassis CM, Venkataraman A, Schmidt TM, Weinstock GM. PMID: 23491408.
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    72. Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Am J Respir Crit Care Med. 2013 May 15; 187(10):1110-7. Lozupone C, Cota-Gomez A, Palmer BE, Linderman DJ, Charlson ES, Sodergren E, Mitreva M, Abubucker S, Martin J, Yao G, Campbell TB, Flores SC, Ackerman G, Stombaugh J, Ursell L, Beck JM, Curtis JL, Young VB, Lynch SV, Huang L, Weinstock GM, Knox KS, Twigg H, Morris A, Ghedin E, Bushman FD, Collman RG, Knight R, Fontenot AP. PMID: 23392441.
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    73. The cystic fibrosis airway microbiome. Cold Spring Harb Perspect Med. 2013 Mar 01; 3(3):a009738. Lynch SV, Bruce KD. PMID: 23457293.
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    74. Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiota. Gut Microbes. 2013 Jan-Feb; 4(1):41-7. Lynch SV, Goldfarb KC, Wild YK, Kong W, De Lisle RC, Brodie EL. PMID: 23060053.
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    75. Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. Sci Transl Med. 2012 Sep 12; 4(151):151ra124. Abreu NA, Nagalingam NA, Song Y, Roediger FC, Pletcher SD, Goldberg AN, Lynch SV. PMID: 22972842.
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    76. Development of a standardized approach for environmental microbiota investigations related to asthma development in children. J Microbiol Methods. 2012 Nov; 91(2):231-9. Fujimura KE, Rauch M, Matsui E, Iwai S, Calatroni A, Lynn H, Mitchell H, Johnson CC, Gern JE, Togias A, Boushey HA, Kennedy S, Lynch SV. PMID: 22975469.
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    77. Oral and airway microbiota in HIV-infected pneumonia patients. J Clin Microbiol. 2012 Sep; 50(9):2995-3002. Iwai S, Fei M, Huang D, Fong S, Subramanian A, Grieco K, Lynch SV, Huang L. PMID: 22760045.
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    79. From microbe to microbiota: considering microbial community composition in infections and airway diseases. Am J Respir Crit Care Med. 2012 Apr 01; 185(7):691-2. Huang YJ, Lynch SV, Wiener-Kronish JP. PMID: 22467799.
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    80. Pseudomonas aeruginosa biofilm-associated homoserine lactone C12 rapidly activates apoptosis in airway epithelia. Cell Microbiol. 2012 May; 14(5):698-709. Schwarzer C, Fu Z, Patanwala M, Hum L, Lopez-Guzman M, Illek B, Kong W, Lynch SV, Machen TE. PMID: 22233488.
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    81. Significance of the microbiome in obstructive lung disease. Thorax. 2012 May; 67(5):456-63. Han MK, Huang YJ, Lipuma JJ, Boushey HA, Boucher RC, Cookson WO, Curtis JL, Erb-Downward J, Lynch SV, Sethi S, Toews GB, Young VB, Wolfgang MC, Huffnagle GB, Martinez FJ. PMID: 22318161.
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    82. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. Am J Respir Crit Care Med. 2012 Apr 15; 185(8):887-92. Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB, Rubenstein RC, Singh PK, Sorscher E, Welsh M. PMID: 22312017.
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    83. PcrV antibody-antibiotic combination improves survival in Pseudomonas aeruginosa-infected mice. Eur J Clin Microbiol Infect Dis. 2012 Aug; 31(8):1837-45. Song Y, Baer M, Srinivasan R, Lima J, Yarranton G, Bebbington C, Lynch SV. PMID: 22187351.
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    85. The potential for probiotic manipulation of the gastrointestinal microbiome. Curr Opin Biotechnol. 2012 Apr; 23(2):192-201. Rauch M, Lynch SV. PMID: 22137452.
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    86. Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa. J Leukoc Biol. 2012 Feb; 91(2):275-84. Xu X, Zhang H, Song Y, Lynch SV, Lowell CA, Wiener-Kronish JP, Caughey GH. PMID: 22075928.
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    87. Role of the microbiota in inflammatory bowel diseases. Inflamm Bowel Dis. 2012 May; 18(5):968-84. Nagalingam NA, Lynch SV. PMID: 21936031.
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    88. Effect of prenatal indoor pet exposure on the trajectory of total IgE levels in early childhood. J Allergy Clin Immunol. 2011 Oct; 128(4):880-885.e4. Havstad S, Wegienka G, Zoratti EM, Lynch SV, Boushey HA, Nicholas C, Ownby DR, Johnson CC. PMID: 21820714.
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    89. Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome. Gastroenterology. 2011 Nov; 141(5):1782-91. Saulnier DM, Riehle K, Mistretta TA, Diaz MA, Mandal D, Raza S, Weidler EM, Qin X, Coarfa C, Milosavljevic A, Petrosino JF, Highlander S, Gibbs R, Lynch SV, Shulman RJ, Versalovic J. PMID: 21741921.
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    90. Differences in biofilm formation and antimicrobial resistance of Pseudomonas aeruginosa isolated from airways of mechanically ventilated patients and cystic fibrosis patients. Int J Antimicrob Agents. 2011 Apr; 37(4):309-15. Fricks-Lima J, Hendrickson CM, Allgaier M, Zhuo H, Wiener-Kronish JP, Lynch SV, Yang K. PMID: 21382698.
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    91. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011 Feb; 127(2):372-381.e1-3. Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV. PMID: 21194740.
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    92. Man's best friend? The effect of pet ownership on house dust microbial communities. J Allergy Clin Immunol. 2010 Aug; 126(2):410-2, 412.e1-3. Fujimura KE, Johnson CC, Ownby DR, Cox MJ, Brodie EL, Havstad SL, Zoratti EM, Woodcroft KJ, Bobbitt KR, Wegienka G, Boushey HA, Lynch SV. PMID: 20633927.
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    93. Nucleic acid extraction efficiency and bacterial recovery from maxillary sinus mucosal samples obtained by brushing or biopsy. Am J Rhinol Allergy. 2010 Jul-Aug; 24(4):263-5. Roediger FC, Slusher NA, Allgaier S, Cox MJ, Pletcher SD, Goldberg AN, Lynch SV. PMID: 20819463.
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    94. Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients. PLoS One. 2010 Jun 23; 5(6):e11044. Cox MJ, Allgaier M, Taylor B, Baek MS, Huang YJ, Daly RA, Karaoz U, Andersen GL, Brown R, Fujimura KE, Wu B, Tran D, Koff J, Kleinhenz ME, Nielson D, Brodie EL, Lynch SV. PMID: 20585638.
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    95. Comparative analyses of the bacterial microbiota of the human nostril and oropharynx. mBio. 2010 Jun 22; 1(3). Lemon KP, Klepac-Ceraj V, Schiffer HK, Brodie EL, Lynch SV, Kolter R. PMID: 20802827.
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    96. Guide to designing, conducting, publishing and communicating results of clinical studies involving probiotic applications in human participants. Gut Microbes. 2010 Jul; 1(4):243-253. Shane AL, Cabana MD, Vidry S, Merenstein D, Hummelen R, Ellis CL, Heimbach JT, Hempel S, Lynch SV, Sanders ME, Tancredi DJ. PMID: 21327031.
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    98. Role of the gut microbiota in defining human health. Expert Rev Anti Infect Ther. 2010 Apr; 8(4):435-54. Fujimura KE, Slusher NA, Cabana MD, Lynch SV. PMID: 20377338.
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    99. Polymorphisms in the Pseudomonas aeruginosa type III secretion protein, PcrV - implications for anti-PcrV immunotherapy. Microb Pathog. 2010 Jun; 48(6):197-204. Lynch SV, Flanagan JL, Sawa T, Fang A, Baek MS, Rubio-Mills A, Ajayi T, Yanagihara K, Hirakata Y, Kohno S, Misset B, Nguyen JC, Wiener-Kronish JP. PMID: 20211240.
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    101. A persistent and diverse airway microbiota present during chronic obstructive pulmonary disease exacerbations. OMICS. 2010 Feb; 14(1):9-59. Huang YJ, Kim E, Cox MJ, Brodie EL, Brown R, Wiener-Kronish JP, Lynch SV. PMID: 20141328.
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    102. Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PLoS One. 2010 Jan 18; 5(1):e8745. Cox MJ, Huang YJ, Fujimura KE, Liu JT, McKean M, Boushey HA, Segal MR, Brodie EL, Cabana MD, Lynch SV. PMID: 20090909.
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    103. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell. 2009 Oct 30; 139(3):485-98. Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, Tanoue T, Imaoka A, Itoh K, Takeda K, Umesaki Y, Honda K, Littman DR. PMID: 19836068.
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    104. Genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays. Infect Immun. 2009 Nov; 77(11):4877-86. Montor WR, Huang J, Hu Y, Hainsworth E, Lynch S, Kronish JW, Ordonez CL, Logvinenko T, Lory S, LaBaer J. PMID: 19737893.
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    105. Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumonia. J Infect. 2009 Jul; 59(1):49-55. El-Solh AA, Amsterdam D, Alhajhusain A, Akinnusi ME, Saliba RG, Lynch SV, Wiener-Kronish JP. PMID: 19535150.
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    106. Novel strategies to combat bacterial virulence. Curr Opin Crit Care. 2008 Oct; 14(5):593-9. Lynch SV, Wiener-Kronish JP. PMID: 18787455.
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    107. Increased mortality of ventilated patients with endotracheal Pseudomonas aeruginosa without clinical signs of infection. Crit Care Med. 2008 Sep; 36(9):2495-503. Zhuo H, Yang K, Lynch SV, Dotson RH, Glidden DV, Singh G, Webb WR, Elicker BM, Garcia O, Brown R, Sawa Y, Misset B, Wiener-Kronish JP. PMID: 18679122.
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    108. Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability. Am J Respir Cell Mol Biol. 2009 Jan; 40(1):108-18. Ganter MT, Roux J, Su G, Lynch SV, Deutschman CS, Weiss YG, Christiaans SC, Myazawa B, Kipnis E, Wiener-Kronish JP, Howard M, Pittet JF. PMID: 18703797.
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    109. Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia. Am J Respir Crit Care Med. 2008 Sep 01; 178(5):513-9. El Solh AA, Akinnusi ME, Wiener-Kronish JP, Lynch SV, Pineda LA, Szarpa K. PMID: 18467510.
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    112. Role of the rapA gene in controlling antibiotic resistance of Escherichia coli biofilms. Antimicrob Agents Chemother. 2007 Oct; 51(10):3650-8. Lynch SV, Dixon L, Benoit MR, Brodie EL, Keyhan M, Hu P, Ackerley DF, Andersen GL, Matin A. PMID: 17664315.
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    113. Microbial manipulation of immune function for asthma prevention: inferences from clinical trials. Proc Am Thorac Soc. 2007 Jul; 4(3):277-82. Yoo J, Tcheurekdjian H, Lynch SV, Cabana M, Boushey HA. PMID: 17607013.
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    114. Loss of bacterial diversity during antibiotic treatment of intubated patients colonized with Pseudomonas aeruginosa. J Clin Microbiol. 2007 Jun; 45(6):1954-62. Flanagan JL, Brodie EL, Weng L, Lynch SV, Garcia O, Brown R, Hugenholtz P, DeSantis TZ, Andersen GL, Wiener-Kronish JP, Bristow J. PMID: 17409203.
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    115. Alveolar hemostasis in patients with species-specific bacterial-mediated ventilator-associated pneumonia. Crit Care Med. 2007 Feb; 35(2):652-3. Song Y, Wiener-Kronish JP, Flanagan J, Lynch SV. PMID: 17251717.
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    116. Increased plasminogen activator inhibitor-1 concentrations in bronchoalveolar lavage fluids are associated with increased mortality in a cohort of patients with Pseudomonas aeruginosa. Anesthesiology. 2007 Feb; 106(2):252-61. Song Y, Lynch SV, Flanagan J, Zhuo H, Tom W, Dotson RH, Baek MS, Rubio-Mills A, Singh G, Kipnis E, Glidden D, Brown R, Garcia O, Wiener-Kronish JP. PMID: 17264718.
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    117. Presence or absence of lipopolysaccharide O antigens affects type III secretion by Pseudomonas aeruginosa. J Bacteriol. 2007 Mar; 189(6):2203-9. Augustin DK, Song Y, Baek MS, Sawa Y, Singh G, Taylor B, Rubio-Mills A, Flanagan JL, Wiener-Kronish JP, Lynch SV. PMID: 17209027.
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    118. Escherichia coli biofilms formed under low-shear modeled microgravity in a ground-based system. Appl Environ Microbiol. 2006 Dec; 72(12):7701-10. Lynch SV, Mukundakrishnan K, Benoit MR, Ayyaswamy PS, Matin A. PMID: 17028231.
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    119. Effect of chromate stress on Escherichia coli K-12. J Bacteriol. 2006 May; 188(9):3371-81. Ackerley DF, Barak Y, Lynch SV, Curtin J, Matin A. PMID: 16621832.
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    120. New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution. Mol Cancer Ther. 2006 Jan; 5(1):97-103. Barak Y, Thorne SH, Ackerley DF, Lynch SV, Contag CH, Matin A. PMID: 16432167.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    121. ChrR, a soluble quinone reductase of Pseudomonas putida that defends against H2O2. J Biol Chem. 2005 Jun 17; 280(24):22590-5. Gonzalez CF, Ackerley DF, Lynch SV, Matin A. PMID: 15840577.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    122. Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques. Gene. 2004 Dec 08; 343(1):107-15. Carmody M, Byrne B, Murphy B, Breen C, Lynch S, Flood E, Finnan S, Caffrey P. PMID: 15563836.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    123. Role and regulation of sigma S in general resistance conferred by low-shear simulated microgravity in Escherichia coli. J Bacteriol. 2004 Dec; 186(24):8207-12. Lynch SV, Brodie EL, Matin A. PMID: 15576768.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    124. Alanine dehydrogenase from the psychrophilic bacterium strain PA-43: overexpression, molecular characterization, and sequence analysis. Extremophiles. 2003 Apr; 7(2):135-43. Irwin JA, Lynch SV, Coughlan S, Baker PJ, Gudmundsson HM, Alfredsson GA, Rice DW, Engel PC. PMID: 12664266.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    125. Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes. Chem Biol. 2001 Jul; 8(7):713-23. Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M. PMID: 11451671.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
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