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John Metcalfe, MD, PhD, MPH

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-476-0735
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    Collapse Biography 
    Collapse Education and Training
    University of California, BerkelyPh.D.2012Division of Epidemiology
    University of California, San FranciscoFellowship2009Pulmonary and Critical Care Medicine
    University of California, San FranciscoResidency 2006Internal Medicine
    Tufts University School of MedicineM.D.2003School of Medicine
    Tufts University School of MedicineMPH2003Chronic Complex Emergencies
    Humboldt State UniversityBS1998Molecular Biology
    Michigan State UniversityAB1995Sociology
    Collapse Awards and Honors
    University of California, Berkeley2008Chancellor's Fellow
    Robert Wood Johnson Foundation2010Harold Amos Scholar
    Doris Duke Charitable Foundation2015Clinical Scientist Development Award

    Collapse Overview 
    Collapse Overview
    John Z. Metcalfe, MD, PhD, MPH is an Associate Professor In Residence in the Division of Pulmonary and Critical Care Medicine at the University of California, San Francisco. A consultant in pulmonary medicine and an intensivist at the Zuckerberg San Francisco General Hospital, John has expertise in critical care and respiratory infectious diseases, with a particular interest in HIV-associated highly drug-resistant tuberculosis clinical management and translational research. He has specialized training in epidemiology, statistical prediction, diagnostic test evaluation, and randomized clinical trials; leads a Fogarty International Center biomedical research training program (NIH D43) in Zimbabwe; and is Chair of an AIDS Clinical Trials Group phase IIc randomized controlled trial evaluating novel regimens for TB treatment shortening. He is also on the Editorial Board of PLoS Medicine, where he is Editor for Respiratory Medicine.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel next-generation sequencing assay for monitoring multidrug resistant tuberculosis treatment in the setting of HIV infection
    NIH/NIAID R01AI131939Jan 19, 2018 - Dec 31, 2022
    Role: Principal Investigator
    Novel methods of pharmacologic monitoring for multidrug resistant tuberculosis treatment in the setting of HIV infection
    NIH/NIAID R01AI123024Jan 7, 2016 - Dec 31, 2020
    Role: Principal Investigator
    Training for Research Excellence and MeNtorship in Tuberculosis (TRENT)
    NIH/FIC D43TW009539Aug 1, 2013 - Mar 31, 2023
    Role: Co-Principal Investigator
    Improving Early Identification of Drug Resistant Tuberculosis in HIV Prevalent Se
    NIH/NIAID K23AI094251Mar 4, 2011 - Feb 29, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Student Projects

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Distinct lung microbiota associate with HIV-associated chronic lung disease in children. Sci Rep. 2020 Sep 30; 10(1):16186. Bhadriraju S, Fadrosh DW, Shenoy MK, Lin DL, Lynch KV, McCauley K, Ferrand RA, Majonga ED, McHugh G, Huang L, Lynch SV, Metcalfe JZ. PMID: 32999331.
      View in: PubMed   Mentions:    Fields:    
    2. Xpert MTB/RIF-detected Rifampicin Resistance is a Sub-Optimal Surrogate for Multidrug Resistant Tuberculosis in Eastern Democratic Republic of the Congo: Diagnostic and Clinical Implications. Clin Infect Dis. 2020 Jun 26. Bisimwa BC, Nachega JB, Warren RM, Theron G, Metcalfe JZ, Shah M, Diacon AH, Sam-Agudu NA, Yotebieng M, Bulabula ANH, Katoto PDMC, Chirambiza JP, Nyota R, Birembano FM, Musafiri EM, Byadunia S, Bahizire E, Kaswa MK, Callens S, Kashongwe ZM. PMID: 32590841.
      View in: PubMed   Mentions: 1     Fields:    
    3. Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29. Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. PMID: 32511538.
      View in: PubMed   Mentions:
    4. Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples. J Vis Exp. 2020 05 19; (159). Reckers A, Wen A, Aguilar D, Bacchetti P, Gandhi M, Metcalfe J, Gerona R. PMID: 32510502.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Presentation and outcome of suspected sepsis in a high-HIV burden, high antiretroviral coverage setting. Int J Infect Dis. 2020 Jul; 96:276-283. Chaka W, Berger C, Huo S, Robertson V, Tachiona C, Magwenzi M, Magombei T, Mpamhanga C, Katzenstein D, Metcalfe J. PMID: 32289564.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Correlation of Linezolid Hair Concentrations with Plasma Exposure in Patients with Drug-Resistant Tuberculosis. Antimicrob Agents Chemother. 2020 02 21; 64(3). Wasserman S, Huo S, Ky K, Malig YN, Esmail A, Dheda K, Bacchetti P, Gerona R, Maartens G, Gandhi M, Metcalfe J. PMID: 31932382.
      View in: PubMed   Mentions:    Fields:    
    7. Minority Mycobacterium tuberculosis Genotypic Populations as an Indicator of Subsequent Phenotypic Resistance. Am J Respir Cell Mol Biol. 2019 12; 61(6):789-791. Engelthaler DM, Streicher EM, Kelley EJ, Allender CJ, Wiggins K, Jimenez D, Lemmer D, Vittinghoff E, Theron G, Sirgel FA, Warren RM, Metcalfe JZ. PMID: 31774334.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Prevalence of drug-resistant tuberculosis in Zimbabwe: A health facility-based cross-sectional survey. Int J Infect Dis. 2019 Oct; 87:119-125. Timire C, Metcalfe JZ, Chirenda J, Scholten JN, Manyame-Murwira B, Ngwenya M, Matambo R, Charambira K, Mutunzi H, Kalisvaart N, Sandy C. PMID: 31357057.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Simultaneous analysis of 11 medications for drug resistant TB in small hair samples to quantify adherence and exposure using a validated LC-MS/MS panel. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 09 01; 1125:121729. Gerona R, Wen A, Aguilar D, Shum J, Reckers A, Bacchetti P, Gandhi M, Metcalfe J. PMID: 31369929.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation. Lancet Glob Health. 2019 06; 7(6):e798-e807. Pooran A, Theron G, Zijenah L, Chanda D, Clowes P, Mwenge L, Mutenherwa F, Lecesse P, Metcalfe J, Sohn H, Hoelscher M, Pym A, Peter J, Dowdy D, Dheda K. PMID: 31097281.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Bedaquiline Microheteroresistance after Cessation of Tuberculosis Treatment. N Engl J Med. 2019 05 30; 380(22):2178-2180. de Vos M, Ley SD, Wiggins KB, Derendinger B, Dippenaar A, Grobbelaar M, Reuter A, Dolby T, Burns S, Schito M, Engelthaler DM, Metcalfe J, Theron G, van Rie A, Posey J, Warren R, Cox H. PMID: 31141643.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. Association of anti-tuberculosis drug concentrations in hair and treatment outcomes in MDR- and XDR-TB. ERJ Open Res. 2019 Apr; 5(2). Metcalfe J, Bacchetti P, Gerona R, Esmail A, Dheda K, Gandhi M. PMID: 31041318.
      View in: PubMed   Mentions:
    13. Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis. Lancet Glob Health. 2019 02; 7(2):e191-e199. Di Tanna GL, Khaki AR, Theron G, McCarthy K, Cox H, Mupfumi L, Trajman A, Zijenah LS, Mason P, Bandason T, Durovni B, Bara W, Hoelscher M, Clowes P, Mangu C, Chanda D, Pym A, Mwaba P, Cobelens F, Nicol MP, Dheda K, Churchyard G, Fielding K, Metcalfe JZ. PMID: 30683238.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    14. Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study. Int J Tuberc Lung Dis. 2019 02 01; 23(2):203-211. Chin AT, Rylance J, Makumbirofa S, Meffert S, Vu T, Clayton J, Mason P, Woodruff P, Metcalfe J. PMID: 30808453.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Tuberculosis outbreak investigation using phylodynamic analysis. Epidemics. 2018 12; 25:47-53. Kühnert D, Coscolla M, Brites D, Stucki D, Metcalfe J, Fenner L, Gagneux S, Stadler T. PMID: 29880306.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    16. Human Immunodeficiency Virus-Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High-Resolution Computed Tomographic Findings. Clin Infect Dis. 2018 01 06; 66(2):274-281. Desai SR, Nair A, Rylance J, Mujuru H, Nathoo K, McHugh G, Majonga E, Metcalfe J, Kranzer K, Ferrand RA. PMID: 29020237.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Cryptic Microheteroresistance Explains Mycobacterium tuberculosis Phenotypic Resistance. Am J Respir Crit Care Med. 2017 11 01; 196(9):1191-1201. Metcalfe JZ, Streicher E, Theron G, Colman RE, Allender C, Lemmer D, Warren R, Engelthaler DM. PMID: 28614668.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    18. Mycobacterium tuberculosis Subculture Results in Loss of Potentially Clinically Relevant Heteroresistance. Antimicrob Agents Chemother. 2017 11; 61(11). Metcalfe JZ, Streicher E, Theron G, Colman RE, Penaloza R, Allender C, Lemmer D, Warren RM, Engelthaler DM. PMID: 28893776.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    19. Defining a Cutoff for Atazanavir in Hair Samples Associated With Virological Failure Among Adolescents Failing Second-Line Antiretroviral Treatment. . 2017 09 01; 76(1):55-59. Chawana TD, Gandhi M, Nathoo K, Ngara B, Louie A, Horng H, Katzenstein D, Metcalfe J, Nhachi CFB. PMID: 28520618.
      View in: PubMed   Mentions:
    20. An LC-MS/MS-based method to analyze the anti-tuberculosis drug bedaquiline in hair. Int J Tuberc Lung Dis. 2017 09 01; 21(9):1069-1070. Metcalfe J, Gerona R, Wen A, Bacchetti P, Gandhi M. PMID: 28826458.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Elucidating the role of clofazimine for the treatment of tuberculosis. Int J Tuberc Lung Dis. 2016 12 01; 20(12):52-57. O'Donnell MR, Padayatchi N, Metcalfe JZ. PMID: 28240574.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    22. Chronic lung disease in HIV-infected children established on antiretroviral therapy. AIDS. 2016 11 28; 30(18):2795-2803. Rylance J, Mchugh G, Metcalfe J, Mujuru H, Nathoo K, Wilmore S, Rowland-Jones S, Majonga E, Kranzer K, Ferrand RA. PMID: 27662546.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    23. Tuberculosis progression rates in U.S. Immigrants following screening with interferon-gamma release assays. BMC Public Health. 2016 08 25; 16(1):875. Blount RJ, Tran MC, Everett CK, Cattamanchi A, Metcalfe JZ, Connor D, Miller CR, Grinsdale J, Higashi J, Nahid P. PMID: 27558397.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. Serial testing for latent tuberculosis using QuantiFERON-TB Gold In-Tube: A Markov model. Sci Rep. 2016 07 29; 6:30781. Moses MW, Zwerling A, Cattamanchi A, Denkinger CM, Banaei N, Kik SV, Metcalfe J, Pai M, Dowdy D. PMID: 27469388.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    25. A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs. Int J Tuberc Lung Dis. 2016 07; 20(7):991-2. Gerona R, Wen A, Koss C, Bacchetti P, Gandhi M, Metcalfe J. PMID: 27287660.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Xpert(®) MTB/RIF detection of rifampin resistance and time to treatment initiation in Harare, Zimbabwe. Int J Tuberc Lung Dis. 2016 07; 20(7):882-9. Metcalfe JZ, Makumbirofa S, Makamure B, Sandy C, Bara W, Mason P, Hopewell PC. PMID: 27287639.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    27. Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. PLoS One. 2016; 11(5):e0155887. Gerona R, Wen A, Chin AT, Koss CA, Bacchetti P, Metcalfe J, Gandhi M. PMID: 27191185.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Re-inventing adherence: toward a patient-centered model of care for drug-resistant tuberculosis and HIV. Int J Tuberc Lung Dis. 2016 Apr; 20(4):430-4. O'Donnell MR, Daftary A, Frick M, Hirsch-Moverman Y, Amico KR, Senthilingam M, Wolf A, Metcalfe JZ, Isaakidis P, Davis JL, Zelnick JR, Brust JC, Naidu N, Garretson M, Bangsberg DR, Padayatchi N, Friedland G. PMID: 26970149.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. G276(P) Chronic respiratory morbidity among HIV-infected children in Zimbabwe; a comparison of ART naïve and treated cohorts. Archives of Disease in Childhood. 2016 Apr 1; 101(Suppl 1):a156. S Rylance, J Rylance, G McHugh, H Mujuru, S Munyati, T Bandason, J Metcalfe, K Kranzer, R Ferrand. .
      View in: Publisher Site   Mentions:
    30. Moving Beyond Directly Observed Therapy for Tuberculosis. PLoS Med. 2015 Sep; 12(9):e1001877. Metcalfe JZ, O'Donnell MR, Bangsberg DR. PMID: 26372602.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    31. Suboptimal specificity of Xpert MTB/RIF among treatment-experienced patients. Eur Respir J. 2015 May; 45(5):1504-6. Metcalfe JZ, Makumbirofa S, Makamure B, Mutetwa R, Peñaloza RA, Sandy C, Bara W, Mungofa S, Hopewell PC, Mason P. PMID: 25792637.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsPHPublic Health
    32. Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spread. J Infect Dis. 2015 Jul 15; 212(2):302-10. Coscolla M, Barry PM, Oeltmann JE, Koshinsky H, Shaw T, Cilnis M, Posey J, Rose J, Weber T, Fofanov VY, Gagneux S, Kato-Maeda M, Metcalfe JZ. PMID: 25601940.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    33. Analysis of Green Light Committee implementation and acquisition of second-line drug resistance. Clin Infect Dis. 2015 Mar 15; 60(6):970. Metcalfe JZ, Vittinghoff E, Hopewell PC. PMID: 25527651.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. Xpert MTB/RIF false detection of rifampin-resistant tuberculosis from prior infection. Am J Respir Crit Care Med. 2014 Dec 01; 190(11):1316-8. Kelly JD, Grace Lin SY, Barry PM, Keh C, Higashi J, Metcalfe JZ. PMID: 25436783.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    35. Reproducibility of interferon gamma (IFN-γ) release Assays. A systematic review. Ann Am Thorac Soc. 2014 Oct; 11(8):1267-76. Tagmouti S, Slater M, Benedetti A, Kik SV, Banaei N, Cattamanchi A, Metcalfe J, Dowdy D, van Zyl Smit R, Dendukuri N, Pai M, Denkinger C. PMID: 25188809.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    36. Empiric tuberculosis treatment in retreatment patients in high HIV/tuberculosis-burden settings. Lancet Infect Dis. 2014 Sep; 14(9):794-5. Metcalfe JZ, Mason P, Mungofa S, Sandy C, Hopewell PC. PMID: 25164190.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    37. Impact of Xpert MTB/RIF on Antiretroviral Therapy-Associated Tuberculosis and Mortality: A Pragmatic Randomized Controlled Trial. Open Forum Infect Dis. 2014 Mar; 1(1):ofu038. Mupfumi L, Makamure B, Chirehwa M, Sagonda T, Zinyowera S, Mason P, Metcalfe JZ, Mutetwa R. PMID: 25734106.
      View in: PubMed   Mentions:
    38. Impact of GeneXpert MTB/RIF on patients and tuberculosis programs in a low-burden setting. a hypothetical trial. Am J Respir Crit Care Med. 2014 Jun 15; 189(12):1551-9. Davis JL, Kawamura LM, Chaisson LH, Grinsdale J, Benhammou J, Ho C, Babst A, Banouvong H, Metcalfe JZ, Pandori M, Hopewell PC, Cattamanchi A. PMID: 24869625.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
    39. Gamma interferon release assays for detection of Mycobacterium tuberculosis infection. Clin Microbiol Rev. 2014 Jan; 27(1):3-20. Pai M, Denkinger CM, Kik SV, Rangaka MX, Zwerling A, Oxlade O, Metcalfe JZ, Cattamanchi A, Dowdy DW, Dheda K, Banaei N. PMID: 24396134.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansCells
    40. Drug-resistant tuberculosis in high-risk groups, Zimbabwe. Emerg Infect Dis. 2014 Jan; 20(1):135-7. Metcalfe JZ, Makumbirofa S, Makamure B, Sandy C, Bara W, Mungofa S, Hopewell PC, Mason P. PMID: 24377879.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    41. Rapid molecular testing for TB to guide respiratory isolation in the U.S.: a cost-benefit analysis. PLoS One. 2013; 8(11):e79669. Millman AJ, Dowdy DW, Miller CR, Brownell R, Metcalfe JZ, Cattamanchi A, Davis JL. PMID: 24278155.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    42. Rifampin monoresistant tuberculosis and HIV comorbidity in California, 1993-2008: a retrospective cohort study. AIDS. 2013 Oct 23; 27(16):2615-22. Prach LM, Pascopella L, Barry PM, Flood J, Porco TC, Hopewell PC, Metcalfe JZ. PMID: 23842135.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    43. A transcriptional signature for active TB: have we found the needle in the haystack? PLoS Med. 2013 Oct; 10(10):e1001539. Cattamanchi A, Walter ND, Metcalfe JZ, Davis JL. PMID: 24167454.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Systematic review of clofazimine for the treatment of drug-resistant tuberculosis. Int J Tuberc Lung Dis. 2013 Aug; 17(8):1001-7. Gopal M, Padayatchi N, Metcalfe JZ, O'Donnell MR. PMID: 23541151.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    45. Tuberculosis and HIV co-infection, California, USA, 1993–2008. Emerg Infect Dis. 2013 Mar; 19(3):400-6. Metcalfe JZ, Porco TC, Westenhouse J, Damesyn M, Facer M, Hill J, Xia Q, Watt JP, Hopewell PC, Flood J. PMID: 23745218.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    46. Microscopic-observation drug-susceptibility assay for the diagnosis of drug-resistant tuberculosis in Harare, Zimbabwe. PLoS One. 2013; 8(2):e55872. Makamure B, Mhaka J, Makumbirofa S, Mutetwa R, Mupfumi L, Mason P, Metcalfe JZ. PMID: 23409072.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    47. Test variability of the QuantiFERON-TB gold in-tube assay in clinical practice. Am J Respir Crit Care Med. 2013 Jan 15; 187(2):206-11. Metcalfe JZ, Cattamanchi A, McCulloch CE, Lew JD, Ha NP, Graviss EA. PMID: 23103734.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    48. Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis. PLoS One. 2012; 7(5):e37956. Dantes R, Metcalfe J, Kim E, Kato-Maeda M, Hopewell PC, Kawamura M, Nahid P, Cattamanchi A. PMID: 22649569.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    49. A causal framework for understanding the effect of losses to follow-up on epidemiologic analyses in clinic-based cohorts: the case of HIV-infected patients on antiretroviral therapy in Africa. Am J Epidemiol. 2012 May 15; 175(10):1080-7. Geng EH, Glidden DV, Bangsberg DR, Bwana MB, Musinguzi N, Nash D, Metcalfe JZ, Yiannoutsos CT, Martin JN, Petersen ML. PMID: 22306557.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    50. Interferon-? release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis. J Infect Dis. 2011 Nov 15; 204 Suppl 4:S1120-9. Metcalfe JZ, Everett CK, Steingart KR, Cattamanchi A, Huang L, Hopewell PC, Pai M. PMID: 21996694.
      View in: PubMed   Mentions: 92     Fields:    Translation:Humans
    51. TB/HIV: an orphan disease? Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1441-2. Brust JC, O'Donnell MR, Metcalfe JZ. PMID: 21642250.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals: a systematic review and meta-analysis. . 2011 Mar 01; 56(3):230-8. Cattamanchi A, Smith R, Steingart KR, Metcalfe JZ, Date A, Coleman C, Marston BJ, Huang L, Hopewell PC, Pai M. PMID: 21239993.
      View in: PubMed   Mentions:
    53. Genotyping of Mycobacterium tuberculosis: application in epidemiologic studies. Future Microbiol. 2011 Feb; 6(2):203-16. Kato-Maeda M, Metcalfe JZ, Flores L. PMID: 21366420.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    54. Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007. Emerg Infect Dis. 2010 Sep; 16(9):1403-9. Metcalfe JZ, Kim EY, Lin SY, Cattamanchi A, Oh P, Flood J, Hopewell PC, Kato-Maeda M. PMID: 20735924.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    55. Evolution of tuberculosis/HIV co-infection in California during the HAART Era, 1996-2007. Retrovirology. 2010 May 1; 7(Suppl 1):o1. John Metcalfe, Matt Facer, Mark Damesyn, Qiang Xia, James Watt, Julia Hill, Philip Hopewell, Janice Westenhouse, Jennifer Flood. .
      View in: Publisher Site   Mentions:
    56. Clinical and radiographic factors do not accurately diagnose smear-negative tuberculosis in HIV-infected inpatients in Uganda: a cross-sectional study. PLoS One. 2010 Mar 26; 5(3):e9859. Davis JL, Worodria W, Kisembo H, Metcalfe JZ, Cattamanchi A, Kawooya M, Kyeyune R, den Boon S, Powell K, Okello R, Yoo S, Huang L. PMID: 20361038.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    57. Evaluation of quantitative IFN-gamma response for risk stratification of active tuberculosis suspects. Am J Respir Crit Care Med. 2010 Jan 01; 181(1):87-93. Metcalfe JZ, Cattamanchi A, Vittinghoff E, Ho C, Grinsdale J, Hopewell PC, Kawamura LM, Nahid P. PMID: 19797760.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    58. Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis. Clin Infect Dis. 2009 Jan 15; 48(2):179-85. Cattamanchi A, Dantes RB, Metcalfe JZ, Jarlsberg LG, Grinsdale J, Kawamura LM, Osmond D, Hopewell PC, Nahid P. PMID: 19086909.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    59. Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil. Emerg Infect Dis. 2008 Mar; 14(3):505-8. Gouveia EL, Metcalfe J, de Carvalho AL, Aires TS, Villasboas-Bisneto JC, Queirroz A, Santos AC, Salgado K, Reis MG, Ko AI. PMID: 18325275.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansPHPublic Health
    60. Endemic malaria in the Peruvian Amazon region of Iquitos. Am J Trop Med Hyg. 2003 Jul; 69(1):45-52. Roshanravan B, Kari E, Gilman RH, Cabrera L, Lee E, Metcalfe J, Calderon M, Lescano AG, Montenegro SH, Calampa C, Vinetz JM. PMID: 12932096.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsPHPublic Health
    61. Carriage of Extended-Spectrum Beta-Lactamase-producing Enterobacteriaceae in HIV-infected children in Zimbabwe. Accepted, Journal of Medical Microbiology. Stephanie Margaret Selike Wilmore, MRCP, MSc; Katharina Kranzer; Alan Williams; Beauty Makamure; Agness Nhdiza; Justin Mayini; Tsitsi Bandason; John Metcalfe; Mark Nicol; Indran Balakrishnan; Matthew Ellington; Neil Woodford; Susan Hopkins; Tim D McHugh; Rashida Ferrand. .