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Mark Segal, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentEpidemiology & Biostatistics
Address550 16th. Street
San Francisco CA 94158
Phone415-514-8034
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    Collapse Research 
    Collapse Research Activities and Funding
    Reconstruction of 3D Genome Architecture from Chromatin Conformation Capture Data
    NIH/NIGMS R01GM109457Sep 1, 2013 - Aug 31, 2021
    Role: Principal Investigator
    ANALYTICAL ASPECTS OF MOLECULAR EPIDEMIOLOGY
    NIH/NIAID R01AI040906Jan 1, 1998 - Dec 31, 2002
    Role: Principal Investigator
    TREE-STRUCTURED SURVIVAL ANALYSIS--METHODS AND SOFTWARE
    NIH/NCI R01CA061054Sep 15, 1993 - Aug 31, 1997
    Role: Principal Investigator
    TREE-STRUCTURED METHODS FOR LONGITUDINAL &SURVIVAL DATA
    NIH/NIGMS R29GM045543Jan 1, 1991 - Dec 31, 1996
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000082Dec 1, 1977 - Nov 30, 2011
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Segal M, Bengtsson HL. Improved accuracy assessment for 3D genome reconstructions. BMC Bioinformatics. 2018 May 30; 19(1):196. PMID: 29848293.
      View in: PubMed
    2. Kaysen GA, Grimes B, Dalrymple LS, Chertow GM, Ishida JH, Delgado C, Segal M, Chiang J, Dwyer T, Johansen KL. Associations of lipoproteins with cardiovascular and infection-related outcomes in patients receiving hemodialysis. J Clin Lipidol. 2018 Mar - Apr; 12(2):481-487.e14. PMID: 29361496.
      View in: PubMed
    3. Méndez-Lagares G, Lu D, Chen C, Terrault N, Segal M, Khalili M, Monto A, Shen H, Manos MM, Lanier LL, Ryan JC, McCune JM, Hartigan-O'Connor DJ. Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success. J Immunol. 2018 Feb 01; 200(3):1124-1132. PMID: 29263212.
      View in: PubMed
    4. Williams SA, Murthy AC, DeLisle RK, Hyde C, Malarstig A, Ostroff R, Weiss SJ, Segal M, Ganz P. Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib. Circulation. 2018 Mar 06; 137(10):999-1010. PMID: 28974520.
      View in: PubMed
    5. Blount RJ, Pascopella L, Catanzaro DG, Barry PM, English PB, Segal M, Flood J, Meltzer D, Jones B, Balmes J, Nahid P. Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California. Environ Health Perspect. 2017 09 29; 125(9):097026. PMID: 28963088.
      View in: PubMed
    6. Leverence R, Nuttall R, Palmer R, Segal M, Wood A, Yancey F, Shuster J, Brantly M, Hromas R. Using Organizational Philosophy to Create a Self-Sustaining Compensation Plan Without Harming Academic Missions. Acad Med. 2017 Aug; 92(8):1133-1137. PMID: 28746136.
      View in: PubMed
    7. Johansen KL, Dalrymple LS, Delgado C, Chertow GM, Segal M, Chiang J, Grimes B, Kaysen GA. Factors Associated with Frailty and Its Trajectory among Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Jul 07; 12(7):1100-1108. PMID: 28576906.
      View in: PubMed
    8. Shenoy MK, Iwai S, Lin DL, Worodria W, Ayakaka I, Byanyima P, Kaswabuli S, Fong S, Stone S, Chang E, Davis JL, Faruqi AA, Segal M, Huang L, Lynch SV. Immune Response and Mortality Risk Relate to Distinct Lung Microbiomes in Patients with HIV and Pneumonia. Am J Respir Crit Care Med. 2017 Jan 01; 195(1):104-114. PMID: 27447987.
      View in: PubMed
    9. Barrette AM, Roberts JK, Chapin C, Egan EA, Segal M, Oses-Prieto JA, Chand S, Burlingame AL, Ballard PL. Antiinflammatory Effects of Budesonide in Human Fetal Lung. Am J Respir Cell Mol Biol. 2016 11; 55(5):623-632. PMID: 27281349.
      View in: PubMed
    10. Auld E, Lin J, Chang E, Byanyima P, Ayakaka I, Musisi E, Worodria W, Davis JL, Segal M, Blackburn E, Huang L. HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected Tuberculosis. PLoS One. 2016; 11(9):e0163153. PMID: 27655116.
      View in: PubMed
    11. Ganz P, Heidecker B, Hveem K, Jonasson C, Kato S, Segal M, Sterling DG, Williams SA. Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease. JAMA. 2016 Jun 21; 315(23):2532-41. PMID: 27327800.
      View in: PubMed
    12. Capurso D, Bengtsson H, Segal M. Discovering hotspots in functional genomic data superposed on 3D chromatin configuration reconstructions. Nucleic Acids Res. 2016 Mar 18; 44(5):2028-35. PMID: 26869583; PMCID: PMC4797302.
    13. Lee CS, Wang RW, Chang HH, Capurso D, Segal M, Haber JE. Chromosome position determines the success of double-strand break repair. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):E146-54. PMID: 26715752; PMCID: PMC4720327.
    14. Segal M, Bengtsson HL. Reconstruction of 3D genome architecture via a two-stage algorithm. BMC Bioinformatics. 2015 Nov 09; 16:373. PMID: 26553003; PMCID: PMC4638111.
    15. Arsuaga J, Jayasinghe RG, Scharein RG, Segal M, Stolz RH, Vazquez M. Current theoretical models fail to predict the topological complexity of the human genome. Front Mol Biosci. 2015; 2:48. PMID: 26347874; PMCID: PMC4543886.
    16. Karski EE, McIlvaine E, Segal M, Krailo M, Grier HE, Granowetter L, Womer RB, Meyers PA, Felgenhauer J, Marina N, DuBois SG. Identification of Discrete Prognostic Groups in Ewing Sarcoma. Pediatr Blood Cancer. 2016 Jan; 63(1):47-53. PMID: 26257296; PMCID: PMC5011751 [Available on 01/01/17].
    17. Capurso D, Segal M. Distance-based assessment of the localization of functional annotations in 3D genome reconstructions. BMC Genomics. 2014 Nov 18; 15:992. PMID: 25407917; PMCID: PMC4254257.
    18. Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal M, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR. Development of a database for translational spinal cord injury research. J Neurotrauma. 2014 Nov 01; 31(21):1789-99. PMID: 25077610; PMCID: PMC4186058.
    19. Bendjilali N, Nelson J, Weinsheimer S, Sidney S, Zaroff JG, Hetts SW, Segal M, Pawlikowska L, McCulloch CE, Young WL, Kim H. Common variants on 9p21.3 are associated with brain arteriovenous malformations with accompanying arterial aneurysms. J Neurol Neurosurg Psychiatry. 2014 Nov; 85(11):1280-3. PMID: 24777168; PMCID: PMC4201968.
    20. Iwai S, Huang D, Fong S, Jarlsberg LG, Worodria W, Yoo S, Cattamanchi A, Davis JL, Kaswabuli S, Segal M, Huang L, Lynch SV. The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients. PLoS One. 2014; 9(4):e95726. PMID: 24752365; PMCID: PMC3994144.
    21. Segal M, Xiong H, Capurso D, Vazquez M, Arsuaga J. Reproducibility of 3D chromatin configuration reconstructions. Biostatistics. 2014 Jul; 15(3):442-56. PMID: 24519450; PMCID: PMC4059464.
    22. Hartigan-O'Connor DJ, Lin D, Ryan JC, Shvachko VA, Cozen ML, Segal M, Terrault NA, Lanier LL, Manos MM, McCune JM. Monocyte activation by interferon a is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection. J Infect Dis. 2014 May 15; 209(10):1602-12. PMID: 24325966; PMCID: PMC3997582.
    23. Liu J, Segal M, Kelly MJ, Pelton JG, Kim M, James TL, Litt L. 13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation. Anesthesiology. 2013 Nov; 119(5):1120-36. PMID: 23748856; PMCID: PMC3890426.
    24. Burrill CP, Westesson O, Schulte MB, Strings VR, Segal M, Andino R. Global RNA structure analysis of poliovirus identifies a conserved RNA structure involved in viral replication and infectivity. J Virol. 2013 Nov; 87(21):11670-83. PMID: 23966409; PMCID: PMC3807356.
    25. Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal M, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9. PMID: 23628816.
      View in: PubMed
    26. Liu J, Sheldon RA, Segal M, Kelly MJ, Pelton JG, Ferriero DM, James TL, Litt L. 1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries. Pediatr Res. 2013 Aug; 74(2):170-9. PMID: 23708689; PMCID: PMC3734529.
    27. Ferguson AR, Irvine KA, Gensel JC, Nielson JL, Lin A, Ly J, Segal M, Ratan RR, Bresnahan JC, Beattie MS. Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats. PLoS One. 2013; 8(3):e59712. PMID: 23544088.
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    28. Capurso D, Xiong H, Segal M. A histone arginine methylation localizes to nucleosomes in satellite II and III DNA sequences in the human genome. BMC Genomics. 2012 Nov 15; 13:630. PMID: 23153121; PMCID: PMC3559892.
    29. Dubois SG, Geier E, Batra V, Yee SW, Neuhaus J, Segal M, Martinez D, Pawel B, Yanik G, Naranjo A, London WB, Kreissman S, Baker D, Attiyeh E, Hogarty MD, Maris JM, Giacomini K, Matthay KK. Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group. Int J Mol Imaging. 2012; 2012:250834. PMID: 23050139; PMCID: PMC3463166.
    30. Bacchetti P, McCulloch C, Segal M. Being 'underpowered' does not make a study unethical. Stat Med. 2012 Dec 20; 31(29):4138-9; author reply 4140-1. PMID: 22763861.
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    31. Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal M, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM. A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet. 2012 Mar 03; 379(9818):823-32. PMID: 22285053; PMCID: PMC3294002.
    32. Segal M, Xiong H, Bengtsson H, Bourgon R, Gentleman R. Querying genomic databases: refining the connectivity map. Stat Appl Genet Mol Biol. 2012 Jan 06; 11(2). PMID: 22499690.
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    33. Xiong H, Capurso D, Sen S, Segal M. Sequence-based classification using discriminatory motif feature selection. PLoS One. 2011; 6(11):e27382. PMID: 22102890; PMCID: PMC3213122.
    34. Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nat Chem Biol. 2011 Oct 30; 7(12):925-34. PMID: 22037470; PMCID: PMC3271120.
    35. Liu J, Litt L, Segal M, Kelly MJ, Pelton JG, Kim M. Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. Int J Mol Sci. 2011; 12(10):6469-501. PMID: 22072900; PMCID: PMC3210991.
    36. DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane JP, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2012 Jul 15; 59(1):52-6. PMID: 21793187; PMCID: PMC3204324.
    37. Okamoto J, Kratz JR, Hirata T, Mikami I, Raz D, Segal M, Chen Z, Zhou HM, Pham P, Li H, Yagui-Beltran A, Beltran A, Ray MR, Koizumi K, Shimizu K, Jablons D, He B. Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients. Clin Lung Cancer. 2011 Jul; 12(4):237-44. PMID: 21726823; PMCID: PMC3285542.
    38. Rehkopf DH, Laraia BA, Segal M, Braithwaite D, Epel E. The relative importance of predictors of body mass index change, overweight and obesity in adolescent girls. Int J Pediatr Obes. 2011 Jun; 6(2-2):e233-42. PMID: 21244233.
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    39. Day LW, Espey DK, Madden E, Segal M, Terdiman JP. Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan natives in the Indian Health Service. Dig Dis Sci. 2011 Jul; 56(7):2104-13. PMID: 21234688; PMCID: PMC3112488.
    40. Segal M, Xiao Y, Huffer FW. Clustering with exclusion zones: genomic applications. Biostatistics. 2011 Apr; 12(2):234-46. PMID: 21051753.
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    41. Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal M, Kroetz DL, Sali A. Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein Sci. 2010 Nov; 19(11):2110-21. PMID: 20799350; PMCID: PMC3005782.
    42. Liu J, Litt L, Segal M, Kelly MJ, Yoshihara HA, James TL. Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab. 2011 Feb; 31(2):547-59. PMID: 20717124; PMCID: PMC3010526.
    43. Ballard PL, Lee JW, Fang X, Chapin C, Allen L, Segal M, Fischer H, Illek B, Gonzales LW, Kolla V, Matthay MA. Regulated gene expression in cultured type II cells of adult human lung. Am J Physiol Lung Cell Mol Physiol. 2010 Jul; 299(1):L36-50. PMID: 20382749; PMCID: PMC2904098.
    44. Day LW, Cello JP, Madden E, Segal M. Prospective assessment of inpatient gastrointestinal consultation requests in an academic teaching hospital. Am J Gastroenterol. 2010 Mar; 105(3):484-9. PMID: 20203634.
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    45. Cox MJ, Huang YJ, Fujimura KE, Liu JT, McKean M, Boushey HA, Segal M, Brodie EL, Cabana MD, Lynch SV. Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PLoS One. 2010 Jan 18; 5(1):e8745. PMID: 20090909; PMCID: PMC2807455.
    46. Barajas RF, Chang JS, Segal M, Parsa AT, McDermott MW, Berger MS, Cha S. Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging. Radiology. 2009 Nov; 253(2):486-96. PMID: 19789240; PMCID: PMC2770116.
    47. Xiao Y, Segal M. Identification of yeast transcriptional regulation networks using multivariate random forests. PLoS Comput Biol. 2009 Jun; 5(6):e1000414. PMID: 19543377; PMCID: PMC2691601.
    48. Donovan MJ, Khan FM, Fernandez G, Mesa-Tejada R, Sapir M, Zubek VB, Powell D, Fogarasi S, Vengrenyuk Y, Teverovskiy M, Segal M, Karnes RJ, Gaffey TA, Busch C, Haggman M, Hlavcak P, Freedland SJ, Vollmer RT, Albertsen P, Costa J, Cordon-Cardo C. Personalized prediction of tumor response and cancer progression on prostate needle biopsy. J Urol. 2009 Jul; 182(1):125-32. PMID: 19450827.
      View in: PubMed
    49. Segal M. A novel topology for representing protein folds. Protein Sci. 2009 Apr; 18(4):686-93. PMID: 19309686; PMCID: PMC2762581.
    50. Raz DJ, Ray MR, Kim JY, He B, Taron M, Skrzypski M, Segal M, Gandara DR, Rosell R, Jablons DM. A multigene assay is prognostic of survival in patients with early-stage lung adenocarcinoma. Clin Cancer Res. 2008 Sep 01; 14(17):5565-70. PMID: 18765549.
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    51. Segal M. On E-values for tandem MS scoring schemes. Bioinformatics. 2008 Jul 15; 24(14):1652-3; author reply 1654. PMID: 18562272.
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    52. Bacchetti P, McCulloch CE, Segal M. Simple, defensible sample sizes based on cost efficiency. Biometrics. 2008 Jun; 64(2):577-85; discussion 586-94. PMID: 18482055; PMCID: PMC2769573.
    53. Segal M. Re-cracking the nucleosome positioning code. Stat Appl Genet Mol Biol. 2008; 7(1):Article14. PMID: 18454729.
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    54. Xiao Y, Segal M. Biological sequence classification utilizing positive and unlabeled data. Bioinformatics. 2008 May 01; 24(9):1198-205. PMID: 18344247.
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    55. Lee SJ, Moody-Ayers SY, Landefeld CS, Walter LC, Lindquist K, Segal M, Covinsky KE. The relationship between self-rated health and mortality in older black and white Americans. J Am Geriatr Soc. 2007 Oct; 55(10):1624-9. PMID: 17697102.
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    56. Xiao Y, Segal M, Yang YH, Yeh RF. A multi-array multi-SNP genotyping algorithm for Affymetrix SNP microarrays. Bioinformatics. 2007 Jun 15; 23(12):1459-67. PMID: 17459966.
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    57. Segal M. Validation in genomics: CpG island methylation revisited. Stat Appl Genet Mol Biol. 2006; 5:Article29. PMID: 17402913.
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    58. Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal M, Weidler J, Grant RM. Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity. AIDS. 2006 Oct 24; 20(16):2123-5. PMID: 17053362.
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    59. Triponez F, Wong M, Sturgeon C, Caron N, Ginzinger DG, Segal M, Kebebew E, Duh QY, Clark OH. Does familial non-medullary thyroid cancer adversely affect survival? World J Surg. 2006 May; 30(5):787-93. PMID: 16479341.
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    60. Lee SJ, Lindquist K, Segal M, Covinsky KE. Development and validation of a prognostic index for 4-year mortality in older adults. JAMA. 2006 Feb 15; 295(7):801-8. PMID: 16478903.
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    61. Segal M. Microarray gene expression data with linked survival phenotypes: diffuse large-B-cell lymphoma revisited. Biostatistics. 2006 Apr; 7(2):268-85. PMID: 16284340.
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    62. Xiao Y, Segal M. Prediction of genomewide conserved epitope profiles of HIV-1: classifier choice and peptide representation. Stat Appl Genet Mol Biol. 2005; 4:Article25. PMID: 16646843.
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    63. Xiao Y, Yang YH, Burckin TA, Shiue L, Hartzog GA, Segal M. Analysis of a splice array experiment elucidates roles of chromatin elongation factor Spt4-5 in splicing. PLoS Comput Biol. 2005 Sep; 1(4):e39. PMID: 16172632; PMCID: PMC1214541.
    64. Mistry AR, Felix CA, Whitmarsh RJ, Mason A, Reiter A, Cassinat B, Parry A, Walz C, Wiemels JL, Segal M, Adès L, Blair IA, Osheroff N, Peniket AJ, Lafage-Pochitaloff M, Cross NC, Chomienne C, Solomon E, Fenaux P, Grimwade D. DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med. 2005 Apr 14; 352(15):1529-38. PMID: 15829534.
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    65. Xiao Y, Segal M, Yang YH. Stepwise normalization of two-channel spotted microarrays. Stat Appl Genet Mol Biol. 2005; 4:Article4. PMID: 16646857.
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    66. Bacchetti P, Wolf LE, Segal M, McCulloch CE. Ethics and sample size. Am J Epidemiol. 2005 Jan 15; 161(2):105-10. PMID: 15632258.
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    67. Yang YH, Xiao Y, Segal M. Identifying differentially expressed genes from microarray experiments via statistic synthesis. Bioinformatics. 2005 Apr 01; 21(7):1084-93. PMID: 15513985.
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    68. Arrasate M, Mitra S, Schweitzer ES, Segal M, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature. 2004 Oct 14; 431(7010):805-10. PMID: 15483602.
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    69. Cummings MP, Segal M. Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis. BMC Bioinformatics. 2004 Sep 28; 5:137. PMID: 15453919; PMCID: PMC524371.
    70. Barbour JD, Hecht FM, Wrin T, Liegler TJ, Ramstead CA, Busch MP, Segal M, Petropoulos CJ, Grant RM. Persistence of primary drug resistance among recently HIV-1 infected adults. AIDS. 2004 Aug 20; 18(12):1683-9. PMID: 15280779.
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    71. Barbour JD, Hecht FM, Wrin T, Segal M, Ramstead CA, Liegler TJ, Busch MP, Petropoulos CJ, Hellmann NS, Kahn JO, Grant RM. Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection. J Infect Dis. 2004 Jul 15; 190(2):251-6. PMID: 15216458.
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    72. Rabert D, Xiao Y, Yiangou Y, Kreder D, Sangameswaran L, Segal M, Hunt CA, Birch R, Anand P. Plasticity of gene expression in injured human dorsal root ganglia revealed by GeneChip oligonucleotide microarrays. J Clin Neurosci. 2004 Apr; 11(3):289-99. PMID: 14975420.
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    73. Pantell RH, Newman TB, Bernzweig J, Bergman DA, Takayama JI, Segal M, Finch SA, Wasserman RC. Management and outcomes of care of fever in early infancy. JAMA. 2004 Mar 10; 291(10):1203-12. PMID: 15010441.
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    74. Segal M, Barbour JD, Grant RM. Relating HIV-1 sequence variation to replication capacity via trees and forests. Stat Appl Genet Mol Biol. 2004; 3:Article2; discussion article 7, article 9. PMID: 16646798.
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    75. Xiao Y, Hunt CA, Segal M, Yang YH. Novel stepwise normalization method for two-channel cDNA microarrays. Conf Proc IEEE Eng Med Biol Soc. 2004; 4:2921-4. PMID: 17270889.
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    76. Reiter A, Saussele S, Grimwade D, Wiemels JL, Segal M, Lafage-Pochitaloff M, Walz C, Weisser A, Hochhaus A, Willer A, Reichert A, Büchner T, Lengfelder E, Hehlmann R, Cross NC. Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia. Genes Chromosomes Cancer. 2003 Feb; 36(2):175-88. PMID: 12508246.
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    77. O'Hare AM, Bacchetti P, Segal M, Hsu CY, Johansen KL. Factors associated with future amputation among patients undergoing hemodialysis: results from the Dialysis Morbidity and Mortality Study Waves 3 and 4. Am J Kidney Dis. 2003 Jan; 41(1):162-70. PMID: 12500233.
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    78. Segal M, Dahlquist KD, Conklin BR. Regression approaches for microarray data analysis. J Comput Biol. 2003; 10(6):961-80. PMID: 14980020.
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    79. Mann JK, Tager IB, Lurmann F, Segal M, Quesenberry CP, Lugg MM, Shan J, Van Den Eeden SK. Air pollution and hospital admissions for ischemic heart disease in persons with congestive heart failure or arrhythmia. Environ Health Perspect. 2002 Dec; 110(12):1247-52. PMID: 12460805; PMCID: PMC1241113.
    80. Barbour JD, Wrin T, Grant RM, Martin JN, Segal M, Petropoulos CJ, Deeks SG. Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults. J Virol. 2002 Nov; 76(21):11104-12. PMID: 12368352; PMCID: PMC136622.
    81. Wiemels JL, Leonard BC, Wang Y, Segal M, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR. Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):15101-6. PMID: 12415113; PMCID: PMC137550.
    82. Xiao Y, Segal M, Rabert D, Ahn AH, Anand P, Sangameswaran L, Hu D, Hunt CA. Assessment of differential gene expression in human peripheral nerve injury. BMC Genomics. 2002 Sep 27; 3(1):28. PMID: 12354329; PMCID: PMC137578.
    83. Keles S, Segal M. Residual-based tree-structured survival analysis. Stat Med. 2002 Jan 30; 21(2):313-26. PMID: 11782067.
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