Navneet Matharu, PhD

Title(s)Associate Researcher, Bioengineering
SchoolSchool of Pharmacy
ORCID ORCID Icon0000-0002-9426-1484 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Delhi, IndiaBachelors in Science2002Zoology
    University of Delhi, IndiaMasters in Science2004Genetics
    Centre for Cellular and Molecular Biology, CSIR, Jawaharlal Nehru University, IndiaPhD2011Molecular Biology and Gene Regulation
    Collapse Awards and Honors
    University of Delhi2002Gold Medal BSc Zoology
    University of Delhi2004Gold Medal MSc Genetics
    University of Delhi1999  - 2002University Scholarship for meritoirus student
    University of Delhi2002  - 2004Monsanto Scholarship for meritorious student
    CSIR, HRD ministry Govt of India2004  - 2006Junior Research Fellowship (JRF) in Life Sciences
    CSIR, HRD ministry Govt of India2006  - 2010Senior Research Fellowship (SRF) in Life Sciences
    Rao Scientific Society, India2011Young Scientist Award, Dr. KV Rao Scientific Society, India
    UCSF2016People’s choice award Postdoc Slam Competition
    American Society of Human Genetics2017Charles J Epstein Trainee Award for Excellence in Human Genetics
    American Society of Human Genetics2017Charles J Epstein Trainee Award for Excellence in Human Genetics
    Regeneron Pharmaceuticals2018Finalist ‘Regeneron Prize for Creative Innovation’
    School of Pharmacy, UCSF2017Mary Ann Koda Kimble Seed award for Innovation
    CTSI, UCSF2018Catalayst Award
    IGI, UC Berkeley2019IGI-RIDER Award

    Collapse Overview 
    Collapse Overview
    Dr. Matharu holds joint appointment as Assistant Professor and Associate Researcher. Dr.Matharu's research interest is focused on applying ‘gene regulation and transcription logics’ to innovate therapeutic strategies for genetic disorders.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transcriptomic Mapping of Neural Diversity, Differentiation and Functional Trajectory in iPSC-Derived 3D Brain Organoid Models. Cells. 2021 12 05; 10(12). Kiaee K, Jodat YA, Bassous NJ, Matharu N, Shin SR. PMID: 34943930; PMCID: PMC8700452.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    2. Oestrogen engages brain MC4R signalling to drive physical activity in female mice. Nature. 2021 11; 599(7883):131-135. Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA. PMID: 34646010; PMCID: PMC9113400.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    3. Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish. Cells Dev. 2021 06; 166:203682. Matharu NK, Yadav S, Kumar M, Mishra RK. PMID: 33994355.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences. Nucleic Acids Res. 2021 01 11; 49(1):e4. Georgakopoulos-Soares I, Mouratidis I, Parada GE, Matharu N, Hemberg M, Ahituv N. PMID: 33211865; PMCID: PMC7797064.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. Toward a neurospheroid niche model: optimizing embedded 3D bioprinting for fabrication of neurospheroid brain-like co-culture constructs. Biofabrication. 2020 11 10; 13(1). Li YE, Jodat YA, Samanipour R, Zorzi G, Zhu K, Hirano M, Chang K, Arnaout A, Hassan S, Matharu N, Khademhosseini A, Hoorfar M, Shin SR. PMID: 33059333; PMCID: PMC8387028.
      View in: PubMed   Mentions: 16     Fields:    
    6. Modulating gene regulation to treat genetic disorders. Nat Rev Drug Discov. 2020 11; 19(11):757-775. Matharu N, Ahituv N. PMID: 33020616.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    7. Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Nat Metab. 2019 04; 1(4):475-484. Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. PMID: 31535083; PMCID: PMC6750255.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    8. Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3349-3350. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30755537; PMCID: PMC6397520.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. Science. 2019 01 18; 363(6424). Matharu N, Rattanasopha S, Tamura S, Maliskova L, Wang Y, Bernard A, Hardin A, Eckalbar WL, Vaisse C, Ahituv N. PMID: 30545847; PMCID: PMC6570489.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    10. Genetic variation in the SIM1 locus is associated with erectile dysfunction. Proc Natl Acad Sci U S A. 2018 10 23; 115(43):11018-11023. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30297428; PMCID: PMC6205494.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    11. Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease. PLoS Genet. 2015 Dec; 11(12):e1005640. Matharu N, Ahituv N. PMID: 26632825; PMCID: PMC4669122.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    12. Chromatin Insulators and Topological Domains: Adding New Dimensions to 3D Genome Architecture. Genes (Basel). 2015 Sep 01; 6(3):790-811. Matharu NK, Ahanger SH. PMID: 26340639; PMCID: PMC4584330.
      View in: PubMed   Mentions: 12     Fields:    
    13. Mining the cis-regulatory elements of Hox clusters. Methods Mol Biol. 2014; 1196:121-31. Matharu NK, Mishra RK. PMID: 25151161.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    14. A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors. Sci Rep. 2013 Oct 22; 3:3011. Vasanthi D, Nagabhushan A, Matharu NK, Mishra RK. PMID: 24145990; PMCID: PMC3804862.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    15. Homeotic gene regulation: a paradigm for epigenetic mechanisms underlying organismal development. Subcell Biochem. 2013; 61:177-207. Matharu NK, Dasari V, Mishra RK. PMID: 23150252.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    16. Tone up your chromatin and stay young. J Biosci. 2011 Mar; 36(1):5-11. Matharu NK, Mishra RK. PMID: 21451241.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Vertebrate homologue of Drosophila GAGA factor. J Mol Biol. 2010 Jul 16; 400(3):434-47. Matharu NK, Hussain T, Sankaranarayanan R, Mishra RK. PMID: 20471984.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells