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Single-cell RNA-sequencing of PBMCs highlights the central role of anti-SSA antibodies and its association with Interferon-stimulated genes in the expression of Sjögren's disease. La Revue de Médecine Interne. 2024 Dec 1; 45:a385-a386.
Urbanski UG, Taylor TK, Flynn FE, Gosh GA, Patel PR, Norouzi NA, Davidson DB, Poon PA, Chu CC, Nititham NJ, Fragiadakis FG, Eckalbar EW, Combes CA, Criswell CL, Ye YJ, Shiboski SC. .
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Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping. bioRxiv. 2024 Nov 25.
Wang K, Nie Y, Maguire C, Syphurs C, Sheen H, Karoly M, Lapp L, Gygi JP, Jayavelu ND, Patel RK, Hoch A, IMPACC Network, Corry D, Kheradmand F, McComsey GA, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, Davis MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Hafler DA, Shaw A, Rahman A, Hough CL, Geng LN, Ozonoff A, Haddad EK, Reed EF, van Bakel H, Kim-Schultz S, Krammer F, Wilson M, Eckalbar W, Bosinger S, Langelier CR, Sekaly RP, Montgomery RR, Maecker HT, Krumholz H, Melamed E, Steen H, Pulendran B, Augustine AD, Cairns CB, Rouphael N, Becker PM, Fourati S, Shannon CP, Smolen KK, Peters B, Kleinstein SH, Levy O, Altman MC, Iwasaki A, Diray-Arce J, Ehrlich LIR, Guan L. PMID: 39651165; PMCID: PMC11623532.
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Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19. bioRxiv. 2024 Nov 16.
Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Sesma AF, Simon V, Metcalf JP, Agudelo Higuita NI, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, IMPACC Network, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E. PMID: 39605478; PMCID: PMC11601417.
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Regulatory T cell-derived enkephalin gates nociception. bioRxiv. 2024 Nov 12.
Midavaine É, Moraes BC, Benitez J, Rodriguez SR, Braz JM, Kochhar NP, Eckalbar WL, Domingos AI, Pintar JE, Basbaum AI, Kashem SW. PMID: 38798460; PMCID: PMC11118376.
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Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks. bioRxiv. 2024 Nov 11.
Mennillo E, Lotstein ML, Lee G, Johri V, Ekstrand C, Tsui J, Hou J, Leet DE, He JY, Mahadevan U, Eckalbar W, Oh DY, Fragiadakis GK, Kattah MG, Combes AJ. PMID: 39605355; PMCID: PMC11601222.
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LB869 Single-cell RNA-seq analysis of circulating immune cells in dermatomyositis in patients with and without a history of cancer. Journal of Investigative Dermatology. 2024 Aug 1; 144(8):s151.
Mintz MM, Kazmi KM, Loya LA, Flynn FE, Maliskova ML, Eckalbar EW, Combes CA, Fragiadakis FG, Cyster CJ, Haemel HA. .
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Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading. bioRxiv. 2024 Jul 31.
Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, Pan S, Nilsson J, Yin X, Bhattacharyya A, Boostanpour K, Jujaray T, Wang J, Tsukui T, Sheppard D, Li B, Maishan M, Taenaka H, Matthay MA, Muramatsu R, Maliskova L, Ghosh A, Eckalbar WL, Molofsky AB, Wolters PJ, Tamaki SJ, Bivona T, Abate AR, Wagner A, Tharp KM, Bhattacharya M. PMID: 39211079; PMCID: PMC11360891.
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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Nat Commun. 2024 Jun 28; 15(1):5483.
Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. PMID: 38942804; PMCID: PMC11213873.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Defective interferon signaling in the circulating monocytes of type 2 diabetic mice. bioRxiv. 2024 Jun 03.
Omodaka S, Kato Y, Sato Y, Falcone-Juengert J, Zhang H, Kanoke A, Eckalbar WL, Endo H, Hsieh CL, Aran D, Liu J. PMID: 38895236; PMCID: PMC11185546.
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Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality. J Clin Invest. 2024 May 01; 134(9).
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Haddad EK, IMPACC Network, Reed EF, Kraft M, McComsey GA, Metcalf JP, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar WL, Maecker HT, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Sekaly RP, Ehrlich LI, Fourati S, Peters B, Kleinstein SH, Guan L. PMID: 38690733; PMCID: PMC11060740.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Sci Transl Med. 2024 Apr 17; 16(743):eadj5154.
Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. PMID: 38630846.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Author Correction: Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Nat Metab. 2024 Mar; 6(3):598.
Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. PMID: 38429391.
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Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis. Nat Commun. 2024 Feb 19; 15(1):1493.
Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. PMID: 38374043; PMCID: PMC10876948.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology. medRxiv. 2024 Feb 13.
Van Phan H, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, Van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns C, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR. PMID: 38405760; PMCID: PMC10888993.
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Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nat Commun. 2024 Jan 03; 15(1):216.
Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LIR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Higuita NIA, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE, IMPACC Network, Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Maecker HT, Altman MC, Montgomery RR, Becker PM, Rouphael N. PMID: 38172101; PMCID: PMC10764789.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Single-cell and spatial multi-omics highlight effects of anti-integrin therapy across cellular compartments in ulcerative colitis. bioRxiv. 2024 Jan 03.
Mennillo E, Kim YJ, Lee G, Rusu I, Patel RK, Dorman LC, Flynn E, Li S, Bain JL, Andersen C, Rao A, Tamaki S, Tsui J, Shen A, Lotstein ML, Rahim M, Naser M, Bernard-Vazquez F, Eckalbar W, Cho SJ, Beck K, El-Nachef N, Lewin S, Selvig DR, Terdiman JP, Mahadevan U, Oh DY, Fragiadakis GK, Pisco A, Combes AJ, Kattah MG. PMID: 36711576; PMCID: PMC9882264.
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Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Res Sq. 2023 Dec 20.
Langelier C, Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, Higuita N, Atkinson M, Breckenridge S, Fung M, Messer W, IMPACC Network, Salehi-Rad R, Altman M, Becker P, Bosinger S, Eckalbar W, Hoch A, Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein S, Krammer F, Maecker H, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed E. PMID: 38196658; PMCID: PMC10775393.
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Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants. bioRxiv. 2023 Nov 06.
Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Network I, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf J, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Augustine AD, Sekaly RP, Ehrlich LIR, Fourati S, Peters B, Kleinstein SH, Guan L. PMID: 37986828; PMCID: PMC10659275.
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Comparative proteomic analysis of tail regeneration in the green anole lizard, Anolis carolinensis. Nat Sci (Weinh). 2024 Jan; 4(1).
Xu C, Hutchins ED, Eckalbar W, Pendarvis K, Benson DM, Lake DF, McCarthy FM, Kusumi K. PMID: 38505006; PMCID: PMC10947082.
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PubMed Mentions:
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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Res Sq. 2023 Aug 03.
Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. PMID: 37577607; PMCID: PMC10418533.
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Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients. Cell Rep Med. 2023 06 20; 4(6):101079.
Diray-Arce J, Fourati S, Doni Jayavelu N, Patel R, Maguire C, Chang AC, Dandekar R, Qi J, Lee BH, van Zalm P, Schroeder A, Chen E, Konstorum A, Brito A, Gygi JP, Kho A, Chen J, Pawar S, Gonzalez-Reiche AS, Hoch A, Milliren CE, Overton JA, Westendorf K, IMPACC Network, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen L, Grubaugh ND, van Bakel H, Wilson M, Rajan J, Steen H, Eckalbar W, Cotsapas C, Langelier CR, Levy O, Altman MC, Maecker H, Montgomery RR, Haddad EK, Sekaly RP, Esserman D, Ozonoff A, Becker PM, Augustine AD, Guan L, Peters B, Kleinstein SH. PMID: 37327781; PMCID: PMC10203880.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Patients with abdominal aortic aneurysms have reduced levels of microRNA 122-5p in circulating exosomes. PLoS One. 2023; 18(2):e0281371.
Lopez JL, Ramirez JL, Phu TA, Duong P, Bouchareychas L, Kuhrau CR, Lin PY, Eckalbar WL, Barczak AJ, Rudolph JD, Maliskova L, Conte MS, Vartanian SM, Raffai RL, Oskowitz AZ. PMID: 36787323; PMCID: PMC9928131.
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Translation:
HumansCells
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Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma. Cell Genom. 2023 Jan 11; 3(1):100229.
Koh KD, Bonser LR, Eckalbar WL, Yizhar-Barnea O, Shen J, Zeng X, Hargett KL, Sun DI, Zlock LT, Finkbeiner WE, Ahituv N, Erle DJ. PMID: 36777184; PMCID: PMC9903679.
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PubMed Mentions:
6 Fields:
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A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange. Dev Cell. 2022 07 11; 57(13):1566-1581.e7.
Zhang K, Yao E, Wang SA, Chuang E, Wong J, Minichiello L, Schroeder A, Eckalbar W, Wolters PJ, Chuang PT. PMID: 35714603; PMCID: PMC9308505.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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The Type 2 Asthma Mediator IL-13 Inhibits Severe Acute Respiratory Syndrome Coronavirus 2 Infection of Bronchial Epithelium. Am J Respir Cell Mol Biol. 2022 04; 66(4):391-401.
Bonser LR, Eckalbar WL, Rodriguez L, Shen J, Koh KD, Ghias K, Zlock LT, Christenson S, Woodruff PG, Finkbeiner WE, Erle DJ. PMID: 34982656; PMCID: PMC8990122.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Sci Immunol. 2022 03 04; 7(69):eabj1080.
O'Leary CE, Sbierski-Kind J, Kotas ME, Wagner JC, Liang HE, Schroeder AW, de Tenorio JC, von Moltke J, Ricardo-Gonzalez RR, Eckalbar WL, Molofsky AB, Schneider C, Locksley RM. PMID: 35245089; PMCID: PMC9166270.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Molecular programs of fibrotic change in aging human lung. Nat Commun. 2021 11 02; 12(1):6309.
Lee S, Islam MN, Boostanpour K, Aran D, Jin G, Christenson S, Matthay MA, Eckalbar WL, DePianto DJ, Arron JR, Magee L, Bhattacharya S, Matsumoto R, Kubota M, Farber DL, Bhattacharya J, Wolters PJ, Bhattacharya M. PMID: 34728633; PMCID: PMC8563941.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Inhibitor Combinations Reveal Wiring of the Proteostasis Network in Prostate Cancer Cells. J Med Chem. 2021 10 14; 64(19):14809-14821.
Shkedi A, Adkisson M, Schroeder A, Eckalbar WL, Kuo SY, Neckers L, Gestwicki JE. PMID: 34606726; PMCID: PMC8806517.
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PubMed Mentions: Fields:
Translation:
HumansCells
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CCR2 deficiency alters activation of microglia subsets in traumatic brain injury. Cell Rep. 2021 09 21; 36(12):109727.
Somebang K, Rudolph J, Imhof I, Li L, Niemi EC, Shigenaga J, Tran H, Gill TM, Lo I, Zabel BA, Schmajuk G, Wipke BT, Gyoneva S, Jandreski L, Craft M, Benedetto G, Plowey ED, Charo I, Campbell J, Ye CJ, Panter SS, Nakamura MC, Eckalbar W, Hsieh CL. PMID: 34551293; PMCID: PMC8594931.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Cbl-b deficiency prevents functional but not phenotypic T cell anergy. J Exp Med. 2021 07 05; 218(7).
Nguyen TTT, Wang ZE, Shen L, Schroeder A, Eckalbar W, Weiss A. PMID: 33974042; PMCID: PMC8117209.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Flow-Cytometric Analysis and Purification of Airway Epithelial-Cell Subsets. Am J Respir Cell Mol Biol. 2021 03; 64(3):308-317.
Bonser LR, Koh KD, Johansson K, Choksi SP, Cheng D, Liu L, Sun DI, Zlock LT, Eckalbar WL, Finkbeiner WE, Erle DJ. PMID: 33196316; PMCID: PMC7909335.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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PubMed Mentions:
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Genomic characterization of the adolescent idiopathic scoliosis-associated transcriptome and regulome. Hum Mol Genet. 2021 01 21; 29(22):3606-3615.
Makki N, Zhao J, Liu Z, Eckalbar WL, Ushiki A, Khanshour AM, Wu J, Rios J, Gray RS, Wise CA, Ahituv N. PMID: 33179741; PMCID: PMC7823110.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome. J Exp Med. 2020 11 02; 217(11).
Deng Z, Chong Z, Law CS, Mukai K, Ho FO, Martinu T, Backes BJ, Eckalbar WL, Taguchi T, Shum AK. PMID: 32725126; PMCID: PMC7596814.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
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Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth. Am J Respir Crit Care Med. 2020 10 01; 202(7):962-972.
Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana J, Seibold MA, Burchard EG. PMID: 32459537; PMCID: PMC7528787.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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On the cross-population generalizability of gene expression prediction models. PLoS Genet. 2020 08; 16(8):e1008927.
Keys KL, Mak ACY, White MJ, Eckalbar WL, Dahl AW, Mefford J, Mikhaylova AV, Contreras MG, Elhawary JR, Eng C, Hu D, Huntsman S, Oh SS, Salazar S, Lenoir MA, Ye JC, Thornton TA, Zaitlen N, Burchard EG, Gignoux CR. PMID: 32797036; PMCID: PMC7449671.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Noncoding SNPs associated with increased GDF15 levels located in a metformin-activated enhancer region upstream of GDF15. Pharmacogenomics. 2020 06; 21(8):509-520.
Linhares ND, Pereira DA, Conceição IM, Franco GR, Eckalbar WL, Ahituv N, Luizon MR. PMID: 32427048.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Development of allergic airway immunity depends on MARCH1-mediated ubiquitination of MHCII and CD86 in dendritic cells. The Journal of Immunology. 2020 May 1; 204(1_Supplement):65.9-65.9.
Castellanos CC, Ren RX, Liang LH, Laidlaw LB, Barczak BA, Rudolph RJ, Eckalbar EW, Huang HX, Cyster CJ, Locksley LR, Erle ED, Ishido IS, Shin SJ. .
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Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha. Mol Biol Evol. 2019 12 01; 36(12):2805-2812.
Hardin A, Nevonen KA, Eckalbar WL, Carbone L, Ahituv N. PMID: 31424545; PMCID: PMC6878952.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. . 2019 Sep 12.
N NM, S SR, S ST, L LM, Y YW, A AB, A AH, WL WE, C CV, N NA. .
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Cell fate analysis in fetal mouse lung reveals distinct pathways for TI and TII cell development. Am J Physiol Lung Cell Mol Physiol. 2019 11 01; 317(5):L653-L666.
Gonzalez R, Leaffer D, Chapin C, Gillespie AM, Eckalbar W, Dobbs L. PMID: 31432712; PMCID: PMC6879897.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Genome of the Komodo dragon reveals adaptations in the cardiovascular and chemosensory systems of monitor lizards. Nat Ecol Evol. 2019 08; 3(8):1241-1252.
Lind AL, Lai YYY, Mostovoy Y, Holloway AK, Iannucci A, Mak ACY, Fondi M, Orlandini V, Eckalbar WL, Milan M, Rovatsos M, Kichigin IG, Makunin AI, Johnson Pokorná M, Altmanová M, Trifonov VA, Schijlen E, Kratochvíl L, Fani R, Velenský P, Rehák I, Patarnello T, Jessop TS, Hicks JW, Ryder OA, Mendelson JR, Ciofi C, Kwok PY, Pollard KS, Bruneau BG. PMID: 31358948; PMCID: PMC6668926.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses. J Exp Med. 2019 09 02; 216(9):2024-2037.
Sin JH, Zuckerman C, Cortez JT, Eckalbar WL, Erle DJ, Anderson MS, Waterfield MR. PMID: 31217192; PMCID: PMC6719416.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Singling out Th2 cells in eosinophilic esophagitis. J Clin Invest. 2019 04 08; 129(5):1830-1832.
Eckalbar WL, Erle DJ. PMID: 30958801; PMCID: PMC6486335.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Nat Metab. 2019 04; 1(4):475-484.
Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. PMID: 31535083; PMCID: PMC6750255.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Abstract TP130: Transcriptome Analysis of Mononuclear Cell Responses After Ischemic Stroke in Type 2 Diabetic Mice. Stroke. 2019 Feb 1; 50(Suppl_1).
Omodaka OS, Kanoke KA, Hsieh HC, Eckalbar EW, Liu LJ. .
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CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. Science. 2019 01 18; 363(6424).
Matharu N, Rattanasopha S, Tamura S, Maliskova L, Wang Y, Bernard A, Hardin A, Eckalbar WL, Vaisse C, Ahituv N. PMID: 30545847; PMCID: PMC6570489.
View in:
PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
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Integrative approach identifies corticosteroid response variant in diverse populations with asthma. J Allergy Clin Immunol. 2019 05; 143(5):1791-1802.
Levin AM, Gui H, Hernandez-Pacheco N, Yang M, Xiao S, Yang JJ, Hochstadt S, Barczak AJ, Eckalbar WL, Rynkowski D, Samedy LA, Kwok PY, Pino-Yanes M, Erle DJ, Lanfear DE, Burchard EG, Williams LK. PMID: 30367910; PMCID: PMC6482107.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Tissue signals imprint ILC2 identity with anticipatory function. Nat Immunol. 2018 10; 19(10):1093-1099.
Ricardo-Gonzalez RR, Van Dyken SJ, Schneider C, Lee J, Nussbaum JC, Liang HE, Vaka D, Eckalbar WL, Molofsky AB, Erle DJ, Locksley RM. PMID: 30201992; PMCID: PMC6202223.
View in:
PubMed Mentions:
224 Fields:
Translation:
AnimalsCells
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Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 2018 06 15; 197(12):1552-1564.
Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. PMID: 29509491; PMCID: PMC6006403.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Complementarity between term-time forcing and delayed vaccination response in explaining irregular dynamics in childhood diseases. Ricerche di Matematica. 2018 Jun 1; 67(1):175-204.
Eckalbar EJ, Eckalbar EW. .
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Comparative Genomics Reveals Accelerated Evolution in Conserved Pathways during the Diversification of Anole Lizards. Genome Biol Evol. 2018 02 01; 10(2):489-506.
Tollis M, Hutchins ED, Stapley J, Rupp SM, Eckalbar WL, Maayan I, Lasku E, Infante CR, Dennis SR, Robertson JA, May CM, Crusoe MR, Bermingham E, DeNardo DF, Hsieh ST, Kulathinal RJ, McMillan WO, Menke DB, Pratt SC, Rawls JA, Sanjur O, Wilson-Rawls J, Wilson Sayres MA, Fisher RE, Kusumi K. PMID: 29360978; PMCID: PMC5798147.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Use antibiotics in cell culture with caution: genome-wide identification of antibiotic-induced changes in gene expression and regulation. Sci Rep. 2017 08 08; 7(1):7533.
Ryu AH, Eckalbar WL, Kreimer A, Yosef N, Ahituv N. PMID: 28790348; PMCID: PMC5548911.
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PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Corrigendum to "Dynamics of an SIR model with vaccination dependent on past prevalence with high order distributed delay" [BioSystems 129 (2015) 50-65]. Biosystems. 2017 01; 151:53.
Eckalbar JC, Eckalbar WL. PMID: 27939914.
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PubMed Mentions: Fields:
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Genomic Characterization of Metformin Hepatic Response. PLoS Genet. 2016 Nov; 12(11):e1006449.
Luizon MR, Eckalbar WL, Wang Y, Jones SL, Smith RP, Laurance M, Lin L, Gallins PJ, Etheridge AS, Wright F, Zhou Y, Molony C, Innocenti F, Yee SW, Giacomini KM, Ahituv N. PMID: 27902686; PMCID: PMC5130177.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Differential expression of conserved and novel microRNAs during tail regeneration in the lizard Anolis carolinensis. BMC Genomics. 2016 05 05; 17:339.
Hutchins ED, Eckalbar WL, Wolter JM, Mangone M, Kusumi K. PMID: 27150582; PMCID: PMC4858913.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus. PLoS Genet. 2016 Mar; 12(3):e1005738.
Booker BM, Friedrich T, Mason MK, VanderMeer JE, Zhao J, Eckalbar WL, Logan M, Illing N, Pollard KS, Ahituv N. PMID: 27019019; PMCID: PMC4809552.
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PubMed Mentions:
36 Fields:
Translation:
Animals
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Transcriptomic and epigenomic characterization of the developing bat wing. Nat Genet. 2016 05; 48(5):528-36.
Eckalbar WL, Schlebusch SA, Mason MK, Gill Z, Parker AV, Booker BM, Nishizaki S, Muswamba-Nday C, Terhune E, Nevonen KA, Makki N, Friedrich T, VanderMeer JE, Pollard KS, Carbone L, Wall JD, Illing N, Ahituv N. PMID: 27019111; PMCID: PMC4848140.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. Nat Commun. 2015 Dec 21; 6:10130.
Jorgenson E, Makki N, Shen L, Chen DC, Tian C, Eckalbar WL, Hinds D, Ahituv N, Avins A. PMID: 26686553; PMCID: PMC4703831.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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DYNAMICS IN AN SIR MODEL WHEN VACCINATION DEMAND FOLLOWS PRIOR LEVELS OF DISEASE PREVALENCE. Advances in Complex Systems. 2015 Nov 1; 18(07n08):1550021.
ECKALBAR EJ, TSOURNOS TP, ECKALBAR EW. .
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Integrated Transcriptomic, Proteomic, and MicroRNA Data Identify Key Regulators of Developmental and Repair Processes During Tail Regeneration in the Green Anole Lizard. The FASEB Journal. 2015 Apr 1; 29.
Hutchins HE, Eckalbar EW, Pendarvis PK, McCarthy MF, Lake LD, Kusumi KK. .
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A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females. Nat Commun. 2015 Mar 18; 6:6452.
Sharma S, Londono D, Eckalbar WL, Gao X, Zhang D, Mauldin K, Kou I, Takahashi A, Matsumoto M, Kamiya N, Murphy KK, Cornelia R, TSRHC Scoliosis Clinical Group, Japan Scoliosis Clinical Research Group, Herring JA, Burns D, Ahituv N, Ikegawa S, Gordon D, Wise CA. PMID: 25784220; PMCID: PMC4365504.
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PubMed Mentions:
69 Fields:
Translation:
HumansAnimalsCells
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Dynamics of an SIR model with vaccination dependent on past prevalence with high-order distributed delay. Biosystems. 2015 Mar; 129:50-65.
Eckalbar JC, Eckalbar WL. PMID: 25555542.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Genome-wide discovery of drug-dependent human liver regulatory elements. PLoS Genet. 2014 Oct; 10(10):e1004648.
Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. PMID: 25275310; PMCID: PMC4183418.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes. Transl Psychiatry. 2014 Sep 02; 4:e431.
Oksenberg N, Haliburton GD, Eckalbar WL, Oren I, Nishizaki S, Murphy K, Pollard KS, Birnbaum RY, Ahituv N. PMID: 25180570; PMCID: PMC4199417.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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Transcriptomic analysis of tail regeneration in the lizard Anolis carolinensis reveals activation of conserved vertebrate developmental and repair mechanisms. PLoS One. 2014; 9(8):e105004.
Hutchins ED, Markov GJ, Eckalbar WL, George RM, King JM, Tokuyama MA, Geiger LA, Emmert N, Ammar MJ, Allen AN, Siniard AL, Corneveaux JJ, Fisher RE, Wade J, DeNardo DF, Rawls JA, Huentelman MJ, Wilson-Rawls J, Kusumi K. PMID: 25140675; PMCID: PMC4139331.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Activation of musculoskeletal development and repair mechanisms in the regenerating lizard tail (344.7). The FASEB Journal. 2014 Apr 1; 28.
Hutchins HE, Tokuyama TM, Eckalbar EW, Fisher FR, Rawls RA, Wilson-Rawls WJ, Kusumi KK. .
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A large-scale view of the evolution of amniote development: insights from somitogenesis in reptiles. Curr Opin Genet Dev. 2013 Aug; 23(4):491-7.
Kusumi K, May CM, Eckalbar WL. PMID: 23499412.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Genome reannotation of the lizard Anolis carolinensis based on 14 adult and embryonic deep transcriptomes. BMC Genomics. 2013 Jan 23; 14:49.
Eckalbar WL, Hutchins ED, Markov GJ, Allen AN, Corneveaux JJ, Lindblad-Toh K, Di Palma F, Alföldi J, Huentelman MJ, Kusumi K. PMID: 23343042; PMCID: PMC3561122.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
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Scoliosis and segmentation defects of the vertebrae. Wiley Interdiscip Rev Dev Biol. 2012 May-Jun; 1(3):401-23.
Eckalbar WL, Fisher RE, Rawls A, Kusumi K. PMID: 23801490.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Somitogenesis in the anole lizard and alligator reveals evolutionary convergence and divergence in the amniote segmentation clock. Dev Biol. 2012 Mar 01; 363(1):308-19.
Eckalbar WL, Lasku E, Infante CR, Elsey RM, Markov GJ, Allen AN, Corneveaux JJ, Losos JB, DeNardo DF, Huentelman MJ, Wilson-Rawls J, Rawls A, Kusumi K. PMID: 22178152.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Major shifts in the evolution of somitogenesis: The reptile Anolis carolinensis represents a fourth type of segmentation clock among vertebrates. Developmental Biology. 2011 Aug 1; 356(1):254.
Eckalbar EW, Lasku LE, Infante IC, DeNardo DD, Losos LJ, Rawls RA, Wilson-Rawls WJ, Kusumi KK. .
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Dynamics of an epidemic model with quadratic treatment. Nonlinear Analysis Real World Applications. 2011 Feb 1; 12(1):320-332.
Eckalbar EJ, Eckalbar EW. .
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Developmental gene activation in tail regeneration in the lizard, Anolis carolinensis. Developmental Biology. 2010 Aug 1; 344(1):519-520.
Markov MG, George GR, Emmert EN, Ammar AM, Eckalbar EW, Wade WJ, DeNardo DD, Rawls RA, Wilson-Rawls WJ, Kusumi KK. .
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Identification of a divergent notch pathway delta ligand in the segmentation clock of the reptile, Anolis carolinensis. Developmental Biology. 2010 Aug 1; 344(1):528.
Eckalbar EW, Infante IC, Emmert EN, Losos LJ, Rawls RA, Wilson-Rawls WJ, Kusumi KK. .
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Genetic Regulation of Somite and Early Spinal Patterning. The Genetics and Development of Scoliosis. 2010 Jan 1; 1-20.
Kusumi KK, Eckalbar EW, Pourquié PO. .
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How many genes are part of the oscillatory network regulating somitogenesis? Developmental analysis and mathematical modeling of genes identified in functional genomic screens. Developmental Biology. 2009 Jul 1; 331(2):466.
Eckalbar EW, Sewell SW, Smith SA, Huynh HE, Gibson GJ, Wilson-Rawls WJ, Caplan CM, Kusumi KK. .
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