Radhika Mathur, PhD

Title(s)Assistant Researcher, Neurological Surgery
SchoolSchool of Medicine
Address1450 Third Street, #933A
San Francisco CA 94158
Phone415-514-1183
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    Collapse Biography 
    Collapse Education and Training
    Harvard University, Cambridge, MAPh.D.05/2017Biological and Biomedical Sciences
    University of California, Berkeley, Berkeley, CABA05/2012Molecular and Cell Biology, Economics
    White House Office Of Science and Technology Policy, Washington, DCInternship12/2016Science Policy
    Collapse Awards and Honors
    Society for Neuro-Oncology (SNO)  - 2020Andrew Parsa Young Investigator Award for Basic/Translational Research
    National Institutes of Health (NIH), National Cancer Institute (NCI)2015  - 2017Ruth L. Kirschstein National Research Service Award (F31)
    Dana-Farber Cancer Institute  - 2015Best Poster Award, Annual Postdoc and Graduate Student Retreat
    Harvard Program In Therapeutics Science  - 2015Best Poster Award, Spring Symposium
    UC Berkeley  - 2012Honors, Molecular and Cell Biology
    UC Berkeley  - 2012High Honors, Economics
    UC Berkeley  - 2012Distinction in General Scholarship

    Collapse Research 
    Collapse Research Activities and Funding
    Three-dimensional characterization of epigenomic intratumoral heterogeneity in IDH-mutant glioma
    NIH F32CA239472Jun 1, 2019 - Dec 31, 2021
    Role: Principal Investigator
    Investigating the role of ARID1A inactivation in colon cancer pathogenesis
    NIH F31CA199994Aug 1, 2015 - Jul 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective. Cell. 2024 01 18; 187(2):446-463.e16. Mathur R, Wang Q, Schupp PG, Nikolic A, Hilz S, Hong C, Grishanina NR, Kwok D, Stevers NO, Jin Q, Youngblood MW, Stasiak LA, Hou Y, Wang J, Yamaguchi TN, Lafontaine M, Shai A, Smirnov IV, Solomon DA, Chang SM, Hervey-Jumper SL, Berger MS, Lupo JM, Okada H, Phillips JJ, Boutros PC, Gallo M, Oldham MC, Yue F, Costello JF. PMID: 38242087; PMCID: PMC10832360.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Whole tumor analysis reveals early origin of the TERT promoter mutation and intercellular heterogeneity in TERT expression. Neuro Oncol. 2023 Dec 23. Appin CL, Hong C, Suwala AK, Hilz S, Mathur R, Solomon DA, Smirnov IV, Stevers NO, Shai A, Wang A, Berger MS, Chang SM, Phillips JJ, Costello JF. PMID: 38141254.
      View in: PubMed   Mentions:    Fields:    
    3. GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer. Cell Rep. 2022 09 20; 40(12):111344. McKinney AM, Mathur R, Stevers NO, Molinaro AM, Chang SM, Phillips JJ, Costello JF. PMID: 36130485; PMCID: PMC9534059.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    4. Abstract 3797: 3D whole tumor analysis of the TERT promoter mutation in gliomas. Cancer Research. 2022 Jun 15; 82(12_Supplement):3797-3797. Appin AC, Suwala SA, Hilz HS, Mathur MR, Smirnov SI, Hong HC, Stevers SN, Shai SA, Wang WA, Berger BM, Chang CS, Phillips PJ, Costello CJ. .
      View in: Publisher Site   Mentions:
    5. Abstract 3621: 3D spatial sampling and integrated omics reveal sources and patterning of intratumoral heterogeneity in glioblastoma. Cancer Research. 2022 Jun 15; 82(12_Supplement):3621-3621. Mathur MR, Wang WQ, Schupp SP, Nikolic NA, Yamaguchi YT, Hilz HS, Hong HC, Smirnov SI, LaFontaine LM, Phillips PJ, Chang CS, Li LY, Lupo LJ, Boutros BP, Gallo GM, Oldham OM, Yue YF, Costello CJ. .
      View in: Publisher Site   Mentions:
    6. PATH-28. RE-DEFINING CLONALITY OF THE TERT PROMOTER MUTATION WITH DEEP SEQUENCING AND MAXIMAL SAMPLING OF NEWLY DIAGNOSED AND RECURRENT GBM AND OLIGODENDROGLIOMA. Neuro-Oncology. 2021 Nov 12; 23(Supplement_6):vi121-vi121. Appin AC, Suwala SA, Hilz HS, Mathur MR, Smirnov SI, Hong HC, Stevers SN, Shai SA, Berger BM, Chang CS, Phillips PJ, Costello CJ. .
      View in: Publisher Site   Mentions:
    7. Epigenomic contributions to tumor cell heterogeneity and plasticity. Nat Genet. 2021 10; 53(10):1403-1404. Mathur R, Costello JF. PMID: 34608295.
      View in: PubMed   Mentions:    Fields:    
    8. ECOA-5. Integrative 3D spatial characterization of genomic and epigenomic intratumoral heterogeneity in glioblastoma. Neuro-Oncology Advances. 2021 Jul 5; 3(Supplement_2):ii2-ii2. Mathur MR, Wang WQ, Schupp SP, Hilz HS, Hong HC, Smirnov SI, Lafontaine LM, Nair ND, Iyyanaki IS, Phillips PJ, Chang CS, Li LY, Lupo LJ, Oldham OM, Yue YF, Costello CJ. .
      View in: Publisher Site   Mentions:
    9. MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence. Neuro Oncol. 2020 11 26; 22(11):1580-1590. Mathur R, Zhang Y, Grimmer MR, Hong C, Zhang M, Bollam S, Petrecca K, Clarke J, Berger MS, Phillips JJ, Oberheim-Bush NA, Molinaro AM, Chang SM, Costello JF. PMID: 32166314; PMCID: PMC8444710.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    10. EPCO-31. EPIGENOMIC INTRATUMORAL HETEROGENEITY OF GLIOBLASTOMA IN THREE-DIMENSIONAL SPACE. Neuro-Oncology. 2020 Nov 9; 22(Supplement_2):ii76-ii76. Mathur MR, Iyyanki IS, Hilz HS, Hong HC, Phillips PJ, Chang CS, Yue YF, Costello CJ. .
      View in: Publisher Site   Mentions:
    11. GENE-35. MGMT PROMOTER METHYLATION IN NEWLY DIAGNOSED LGG AS A POTENTIAL BIOMARKER FOR TMZ-ASSOCIATED HYPERMUTATION AT RECURRENCE. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi105-vi105. Mathur MR, Zhang ZY, Grimmer GM, Hong HC, Berger BM, Molinaro MA, Ann Oberheim-Bush AN, Chang CS, Costello CJ. .
      View in: Publisher Site   Mentions:
    12. ARID1A loss in cancer: Towards a mechanistic understanding. Pharmacol Ther. 2018 10; 190:15-23. Mathur R. PMID: 29730444.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    13. SWI/SNF (BAF) Complexes: Guardians of the Epigenome. Annual Review of Cancer Biology. 2018 Mar 4; 2(1):1-15. Mathur MR, Roberts RC. .
      View in: Publisher Site   Mentions:
    14. SWI/SNF (BAF) Complexes: Guardians of the Epigenome. Annual Review of Cancer Biology. 2017; 2:413-427. Radhika Mathur, Charles W. M. Roberts. View Publication.
    15. Abstract LB-286: ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice. Molecular and Cellular Biology, Genetics. 2017 Jul 1; lb-286-lb-286. Mathur MR, Alver AB, Roman RA, Wilson WB, Wang WX, Agoston AA, Park PP, Shivdasani SR, Roberts RC. .
      View in: Publisher Site   Mentions:
    16. ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice. Nat Genet. 2017 Feb; 49(2):296-302. Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW. PMID: 27941798; PMCID: PMC5285448.
      View in: PubMed   Mentions: 169     Fields:    Translation:HumansAnimalsCells
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