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Annette Molinaro, PhD

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Address1450 Third St
San Francisco CA 94158
Phone415-476-1640
ORCID ORCID Icon0000-0002-9854-7404 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Awards and Honors
    UCSF2013Diane D. Ralston Clinical and Basic Neuroscience Teaching Award
    Yale University School of Public Health2008Teacher of the Year Award
    International Statistical Institute2006Elected as a Member
    University of California, Berkeley2004Chin Long Chiang Biostatistics Student of the Year
    University of California, Berkeley2004Evelyn Fix Prize

    Collapse Overview 
    Collapse Overview
    Dr. Molinaro is a principal investigator in the Brain Tumor Research Center at UCSF and the Co-Director of the Clinical and Biostatistics Core for the newly funded UCSF Brain SPORE as well as the Co-Director of the Biospecimen and Biostatistics Core for the newly funded UCSF Brain P01. Dr. Molinaro’s research interests are primarily focused on statistical genetics and computational biology, including prediction, survival analysis and classification with additional curiosities in cancer epidemiology and in the estimation of absolute risk in stratified case-cohort studies. Her research has pertained to predicting clinical outcomes with high-dimensional explanatory variables, such as SNP and methylation arrays, and large-scale epidemiology studies. This has included an adaptation to Classification and Regression Trees (CART) for survival outcomes, the introduction of partDSA, a novel data-adaptive algorithm that builds Boolean combinations of explanatory variables, and a non-parametric method for point estimation based on a stratified case-cohort study design. Dr. Molinaro was recently awarded an R01 by the NCI to expand partDSA for building risk models accommodating various study designs and competing risks. In addition, she has worked with collaborators at the National Cancer Institute (NCI) on comparing cross-validation approaches to validating predictors in small sample sizes and the power of data mining methods for detecting genetic associations and interactions.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Tree-based Statistical Methods for Cancer Risk Prediction
    NIH R01CA163687Jul 10, 2012 - Apr 30, 2018
    Role: Principal Investigator
    Statistical Methods for Predicting Survival Outcomes from Genomic Data
    NIH K22CA123146Jul 6, 2006 - Jun 30, 2009
    Role: Principal Investigator
    Yale SPORE in Skin Cancer
    NIH P50CA121974Jun 1, 2006 - Aug 31, 2017
    Role: Co-Investigator
    Brain Tumor SPORE Grant
    NIH P50CA097257Sep 20, 2002 - Aug 31, 2023
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Smoking Is an Independent Risk Factor for 90-Day Readmission and Reoperation Following Posterior Cervical Decompression and Fusion. Neurosurgery. 2021 Feb 11. Badiee RK, Chan AK, Rivera J, Molinaro A, Chou D, Mummaneni PV, Tan LA. PMID: 33575788.
      View in: PubMed   Mentions:    Fields:    
    2. The Relationship Between Stimulation Current and Functional Site Localization During Brain Mapping. Neurosurgery. 2020 Dec 08. Muster RH, Young JS, Woo PYM, Morshed RA, Warrier G, Kakaizada S, Molinaro AM, Berger MS, Hervey-Jumper SL. PMID: 33289525.
      View in: PubMed   Mentions:    Fields:    
    3. Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest. 2020 Dec 01; 130(12):6325-6337. Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H. PMID: 32817593.
      View in: PubMed   Mentions: 2     Fields:    
    4. MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence. Neuro Oncol. 2020 Nov 26; 22(11):1580-1590. Mathur R, Zhang Y, Grimmer MR, Hong C, Zhang M, Bollam S, Petrecca K, Clarke J, Berger MS, Phillips JJ, Oberheim-Bush NA, Molinaro AM, Chang SM, Costello JF. PMID: 32166314.
      View in: PubMed   Mentions: 4     Fields:    
    5. Adult diffuse glioma GWAS by molecular subtype identifies variants in D2HGDH and FAM20C. Neuro Oncol. 2020 11 26; 22(11):1602-1613. Eckel-Passow JE, Drucker KL, Kollmeyer TM, Kosel ML, Decker PA, Molinaro AM, Rice T, Praska CE, Clark L, Caron A, Abyzov A, Batzler A, Song JS, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Wiemels J, Wiencke JK, Francis S, Burns TC, Giannini C, Lachance DH, Wrensch M, Jenkins RB. PMID: 32386320.
      View in: PubMed   Mentions:    Fields:    
    6. Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma. Clin Cancer Res. 2021 Feb 15; 27(4):1048-1057. PMID: 33199490.
      View in: PubMed   Mentions:    Fields:    
    7. Clinical, radiologic, and genetic characteristics of histone H3 K27M-mutant diffuse midline gliomas in adults. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa142. Schulte JD, Buerki RA, Lapointe S, Molinaro AM, Zhang Y, Villanueva-Meyer JE, Perry A, Phillips JJ, Tihan T, Bollen AW, Pekmezci M, Butowski N, Oberheim Bush NA, Taylor JW, Chang SM, Theodosopoulos P, Aghi MK, Hervey-Jumper SL, Berger MS, Solomon DA, Clarke JL. PMID: 33354667.
      View in: PubMed   Mentions:
    8. Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas. Neuro Oncol. 2020 10 14; 22(10):1516-1526. Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM. PMID: 32319527.
      View in: PubMed   Mentions:    Fields:    
    9. Consensus-based perioperative protocols during the COVID-19 pandemic. J Neurosurg Spine. 2020 Oct 02; 1-9. PMID: 33007752.
      View in: PubMed   Mentions:    Fields:    
    10. Rate of radiation-induced microbleed formation on 7T MRI relates to cognitive impairment in young patients treated with radiation therapy for a brain tumor. Radiother Oncol. 2020 Sep 20; 154:145-153. Morrison MA, Mueller S, Felton E, Jakary A, Stoller S, Avadiappan S, Yuan J, Molinaro AM, Braunstein S, Banerjee A, Hess CP, Lupo JM. PMID: 32966846.
      View in: PubMed   Mentions:    Fields:    
    11. Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002). Oncotarget. 2020 May 26; 11(21):1942-1952. Nicolaides T, Nazemi KJ, Crawford J, Kilburn L, Minturn J, Gajjar A, Gauvain K, Leary S, Dhall G, Aboian M, Robinson G, Long-Boyle J, Wang H, Molinaro AM, Mueller S, Prados M. PMID: 32523649.
      View in: PubMed   Mentions:    Fields:    
    12. The influence of race and socioeconomic status on therapeutic clinical trial screening and enrollment. J Neurooncol. 2020 May; 148(1):131-139. Morshed RA, Reihl SJ, Molinaro AM, Kakaizada S, Young JS, Schulte JD, Butowski N, Taylor J, Bush NA, Aghi MK, Berger MS, Chang S, Clarke J, Hervey-Jumper SL. PMID: 32350780.
      View in: PubMed   Mentions:    Fields:    
    13. The impact of obesity on perioperative complications in patients undergoing anterior lumbar interbody fusion. J Neurosurg Spine. 2020 Apr 24; 1-10. Safaee MM, Tenorio A, Osorio JA, Choy W, Amara D, Lai L, Molinaro AM, Zhang Y, Hu SS, Tay B, Burch S, Berven SH, Deviren V, Dhall SS, Chou D, Mummaneni PV, Eichler CM, Ames CP, Clark AJ. PMID: 32330881.
      View in: PubMed   Mentions:    Fields:    
    14. Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma. JAMA Oncol. 2020 04 01; 6(4):495-503. Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, Han SJ, Chunduru P, Zhang Y, Phillips JJ, Shai A, Lafontaine M, Crane J, Chandra A, Flanigan P, Jahangiri A, Cioffi G, Ostrom Q, Anderson JE, Badve C, Barnholtz-Sloan J, Sloan AE, Erickson BJ, Decker PA, Kosel ML, LaChance D, Eckel-Passow J, Jenkins R, Villanueva-Meyer J, Rice T, Wrensch M, Wiencke JK, Oberheim Bush NA, Taylor J, Butowski N, Prados M, Clarke J, Chang S, Chang E, Aghi M, Theodosopoulos P, McDermott M, Berger MS. PMID: 32027343.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    15. Residual Tumor Volume and Location Predict Progression After Primary Subtotal Resection of Sporadic Vestibular Schwannomas: A Retrospective Volumetric Study. Neurosurgery. 2020 03 01; 86(3):410-416. Breshears JD, Morshed RA, Molinaro AM, McDermott MW, Cheung SW, Theodosopoulos PV. PMID: 31232426.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Safety of Outpatient Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis. Neurosurgery. 2020 01 01; 86(1):30-45. Yerneni K, Burke JF, Chunduru P, Molinaro AM, Riew KD, Traynelis VC, Tan LA. PMID: 30690479.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Longitudinal molecular trajectories of diffuse glioma in adults. Nature. 2019 12; 576(7785):112-120. Barthel FP, Johnson KC, Varn FS, Moskalik AD, Tanner G, Kocakavuk E, Anderson KJ, Abiola O, Aldape K, Alfaro KD, Alpar D, Amin SB, Ashley DM, Bandopadhayay P, Barnholtz-Sloan JS, Beroukhim R, Bock C, Brastianos PK, Brat DJ, Brodbelt AR, Bruns AF, Bulsara KR, Chakrabarty A, Chakravarti A, Chuang JH, Claus EB, Cochran EJ, Connelly J, Costello JF, Finocchiaro G, Fletcher MN, French PJ, Gan HK, Gilbert MR, Gould PV, Grimmer MR, Iavarone A, Ismail A, Jenkinson MD, Khasraw M, Kim H, Kouwenhoven MCM, LaViolette PS, Li M, Lichter P, Ligon KL, Lowman AK, Malta TM, Mazor T, McDonald KL, Molinaro AM, Nam DH, Nayyar N, Ng HK, Ngan CY, Niclou SP, Niers JM, Noushmehr H, Noorbakhsh J, Ormond DR, Park CK, Poisson LM, Rabadan R, Radlwimmer B, Rao G, Reifenberger G, Sa JK, Schuster M, Shaw BL, Short SC, Smitt PAS, Sloan AE, Smits M, Suzuki H, Tabatabai G, Van Meir EG, Watts C, Weller M, Wesseling P, Westerman BA, Widhalm G, Woehrer A, Yung WKA, Zadeh G, Huse JT, De Groot JF, Stead LF, Verhaak RGW. PMID: 31748746.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    18. EGFR amplification status for clinical trial inclusion: where do we draw the line? Neuro Oncol. 2019 10 09; 21(10):1215-1216. Molinaro AM, Phillips JJ. PMID: 31504815.
      View in: PubMed   Mentions:    Fields:    
    19. Preoperative Narcotic Use, Impaired Ambulation Status, and Increased Intraoperative Blood Loss Are Independent Risk Factors for Complications Following Posterior Cervical Laminectomy and Fusion Surgery. Neurospine. 2019 Sep; 16(3):548-557. Badiee RK, Chan AK, Rivera J, Molinaro A, Doherty BR, Riew KD, Chou D, Mummaneni PV, Tan LA. PMID: 31607087.
      View in: PubMed   Mentions:
    20. Phase I trial of caudate deep brain stimulation for treatment-resistant tinnitus. J Neurosurg. 2019 Sep 24; 1-10. Cheung SW, Racine CA, Henderson-Sabes J, Demopoulos C, Molinaro AM, Heath S, Nagarajan SS, Bourne AL, Rietcheck JE, Wang SS, Larson PS. PMID: 31553940.
      View in: PubMed   Mentions:    Fields:    
    21. Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter. J Endocrinol Invest. 2020 Feb; 43(2):149-155. Molinaro A, Orlandi P, Niccolai F, Agretti P, De Marco G, Ferrarini E, Di Cosmo C, Vitti P, Piaggi P, Di Desidero T, Bocci G, Tonacchera M. PMID: 31376092.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. A historical cohort of temporal lobe surgery for medically refractory epilepsy: a systematic review and meta-analysis to guide future nonrandomized controlled trial studies. J Neurosurg. 2019 Jun 28; 1-8. Lee AT, Burke JF, Chunduru P, Molinaro AM, Knowlton R, Chang EF. PMID: 31252393.
      View in: PubMed   Mentions: 1     Fields:    
    23. Genetic and molecular epidemiology of adult diffuse glioma. Nat Rev Neurol. 2019 07; 15(7):405-417. Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR. PMID: 31227792.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    24. Factor analysis for survival time prediction with informative censoring and diverse covariates. Stat Med. 2019 09 10; 38(20):3719-3732. McCurdy S, Molinaro A, Pachter L. PMID: 31162708.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. An independently validated nomogram for isocitrate dehydrogenase-wild-type glioblastoma patient survival. Neurooncol Adv. 2019 May-Dec; 1(1):vdz007. Gittleman H, Cioffi G, Chunduru P, Molinaro AM, Berger MS, Sloan AE, Barnholtz-Sloan JS. PMID: 31608326.
      View in: PubMed   Mentions:
    26. Reirradiation of recurrent high-grade glioma and development of prognostic scores for progression and survival. Neurooncol Pract. 2019 Sep; 6(5):364-374. Chapman CH, Hara JH, Molinaro AM, Clarke JL, Oberheim Bush NA, Taylor JW, Butowski NA, Chang SM, Fogh SE, Sneed PK, Nakamura JL, Raleigh DR, Braunstein SE. PMID: 31555451.
      View in: PubMed   Mentions:
    27. A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium. Int J Cancer. 2019 10 01; 145(7):1889-1901. Mueller S, Jain P, Liang WS, Kilburn L, Kline C, Gupta N, Panditharatna E, Magge SN, Zhang B, Zhu Y, Crawford JR, Banerjee A, Nazemi K, Packer RJ, Petritsch CK, Truffaux N, Roos A, Nasser S, Phillips JJ, Solomon D, Molinaro A, Waanders AJ, Byron SA, Berens ME, Kuhn J, Nazarian J, Prados M, Resnick AC. PMID: 30861105.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    28. Using germline variants to estimate glioma and subtype risks. Neuro Oncol. 2019 03 18; 21(4):451-461. Eckel-Passow JE, Decker PA, Kosel ML, Kollmeyer TM, Molinaro AM, Rice T, Caron AA, Drucker KL, Praska CE, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Erickson BJ, Lucchinetti CF, Wiemels JL, Wiencke JK, Bondy ML, Melin B, Burns TC, Giannini C, Lachance DH, Wrensch MR, Jenkins RB. PMID: 30624711.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Longer genotypically-estimated leukocyte telomere length is associated with increased meningioma risk. J Neurooncol. 2019 May; 142(3):479-487. Muskens IS, Hansen HM, Smirnov IV, Molinaro AM, Bondy ML, Schildkraut JM, Wrensch M, Wiemels JL, Claus EB. PMID: 30796745.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    30. Risk factors of radiotherapy-induced cerebral microbleeds and serial analysis of their size compared with white matter changes: A 7T MRI study in 113 adult patients with brain tumors. J Magn Reson Imaging. 2019 09; 50(3):868-877. Morrison MA, Hess CP, Clarke JL, Butowski N, Chang SM, Molinaro AM, Lupo JM. PMID: 30663150.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    31. Temporal Dynamics of Pseudoprogression After Gamma Knife Radiosurgery for Vestibular Schwannomas-A Retrospective Volumetric Study. Neurosurgery. 2019 01 01; 84(1):123-131. Breshears JD, Chang J, Molinaro AM, Sneed PK, McDermott MW, Tward A, Theodosopoulos PV. PMID: 29518221.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. Neurosurgery. 2018 12 01; 83(6):1161-1172. PMID: 29462362.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Impact of pretreatment growth on Tumor control for vestibular schwannomas following gamma knife. Laryngoscope. 2019 03; 129(3):743-747. Chang J, Breshears JD, Molinaro AM, Sneed PK, McDermott MW, Theodosopoulos PV, Tward AD. PMID: 30408172.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma. J Neurooncol. 2018 Nov; 140(2):477-483. Taylor JW, Parikh M, Phillips JJ, James CD, Molinaro AM, Butowski NA, Clarke JL, Oberheim-Bush NA, Chang SM, Berger MS, Prados M. PMID: 30151703.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    35. Relationship of In Vivo MR Parameters to Histopathological and Molecular Characteristics of Newly Diagnosed, Nonenhancing Lower-Grade Gliomas. Transl Oncol. 2018 Aug; 11(4):941-949. PMID: 29883968.
      View in: PubMed   Mentions:
    36. Disparities in health care determine prognosis in newly diagnosed glioblastoma. Neurosurg Focus. 2018 06; 44(6):E16. Chandra A, Rick JW, Dalle Ore C, Lau D, Nguyen AT, Carrera D, Bonte A, Molinaro AM, Theodosopoulos PV, McDermott MW, Berger MS, Aghi MK. PMID: 29852776.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma. Neurosurgery. 2018 Jan 01; 82(1):64-75. PMID: 28475720.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Improved Survival with Decreased Wait Time to Surgery in Glioblastoma Patients Presenting with Seizure. Neurosurgery. 2017 Nov 01; 81(5):824-833. Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Rick JW, Chang SM, Molinaro AM, McDermott MW, Berger MS, Aghi MK. PMID: 28541497.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma. Clin Cancer Res. 2018 01 15; 24(2):295-305. Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, Maggiora GM, Peng S, Nasser S, Liang WS, Trent JM, Berens ME, Carpten JD, Craig DW, Prados MD. PMID: 29074604.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    40. Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients. J Neurooncol. 2018 Jan; 136(1):33-39. Jacobs DI, Liu Y, Gabrusiewicz K, Tsavachidis S, Armstrong GN, Zhou R, Wei J, Ivan C, Calin G, Molinaro AM, Rice T, Bracci PM, Hansen HM, Wiencke JK, Wrensch MR, Heimberger AB, Bondy ML. PMID: 28965162.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    41. Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor. Transl Oncol. 2017 Dec; 10(6):895-903. PMID: 28942218.
      View in: PubMed   Mentions:
    42. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10743-10748. Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, Cairncross JG, Perry A, Nelson SJ, Chang SM, Bollen AW, Molinaro AM, Bengtsson H, Olshen AB, Weiss S, Phillips JJ, Luchman HA, Costello JF. PMID: 28916733.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    43. Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas. Cancer. 2017 Dec 01; 123(23):4631-4639. PMID: 28759109.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    44. Identifying Voxels at Risk for Progression in Glioblastoma Based on Dosimetry, Physiologic and Metabolic MRI. Radiat Res. 2017 09; 188(3):303-313. Anwar M, Molinaro AM, Morin O, Chang SM, Haas-Kogan DA, Nelson SJ, Lupo JM. PMID: 28723274.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    45. Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma. Sci Rep. 2017 03 22; 7:44792. PMID: 28327577.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    46. Family-centred care for children and young people with cerebral palsy: results from an Italian multicenter observational study. Child Care Health Dev. 2017 07; 43(4):588-597. PMID: 28281289.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT. Acta Neuropathol. 2017 06; 133(6):1001-1016. PMID: 28255664.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    48. Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen. Neuro Oncol. 2017 03 01; 19(3):430-439. PMID: 27576874.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    49. A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma. Cancer Chemother Pharmacol. 2017 03; 79(3):603-610. PMID: 28233053.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    50. Clinical trial endpoints for patients with gliomas. Neurooncol Pract. 2017 Dec; 4(4):201-208. Taylor JW, Molinaro AM, Butowski N, Prados M. PMID: 31385993.
      View in: PubMed   Mentions:
    51. Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survival. Clin Epigenetics. 2017; 9:10. PMID: 28184256.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    52. Chemotherapy for adult low-grade gliomas: clinical outcomes by molecular subtype in a phase II study of adjuvant temozolomide. Neuro Oncol. 2017 02 01; 19(2):242-251. PMID: 27571885.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    53. GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance. JCI Insight. 2017 01 26; 2(2):e88815. PMID: 28138554.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    54. Quantitative multi-modal MR imaging as a non-invasive prognostic tool for patients with recurrent low-grade glioma. J Neurooncol. 2017 03; 132(1):171-179. PMID: 28124178.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience. Neurosurgery. 2017 Jan 01; 80(1):129-139. Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK. PMID: 27428784.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    56. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Cancer Epidemiol. 2017 02; 46:66-72. PMID: 28039770.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    57. GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. Oncotarget. 2016 Nov 29; 7(48):79101-79116. PMID: 27738329.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    58. Cost-Effectiveness Analysis of Surgical versus Medical Treatment of Prolactinomas. J Neurol Surg B Skull Base. 2017 Apr; 78(2):125-131. PMID: 28321375.
      View in: PubMed   Mentions:
    59. Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma. J Neurooncol. 2016 12; 130(3):543-552. PMID: 27624915.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    60. Phase I cancer clinical trials. Neurooncol Pract. 2017 Mar; 4(1):67-72. Cabrera JR, Taylor JW, Molinaro AM. PMID: 31385964.
      View in: PubMed   Mentions:
    61. Presence of cerebral microbleeds is associated with worse executive function in pediatric brain tumor survivors. Neuro Oncol. 2016 11; 18(11):1548-1558. PMID: 27540084.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    62. Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab. J Neurooncol. 2016 10; 130(1):171-179. PMID: 27535746.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    63. Risk prediction for local versus regional/metastatic tumors after initial ductal carcinoma in situ diagnosis treated by lumpectomy. Breast Cancer Res Treat. 2016 06; 157(2):351-361. PMID: 27146587.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    64. Doubly robust survival trees. Stat Med. 2016 09 10; 35(20):3595-612. PMID: 27037609.
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    65. Ureteral Stones: Implementation of a Reduced-Dose CT Protocol in Patients in the Emergency Department with Moderate to High Likelihood of Calculi on the Basis of STONE Score. Radiology. 2016 09; 280(3):743-51. PMID: 26943230.
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    66. PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells. Int J Cancer. 2016 Jul 01; 139(1):99-111. PMID: 26874904.
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    67. Magnetic resonance analysis of malignant transformation in recurrent glioma. Neuro Oncol. 2016 08; 18(8):1169-79. PMID: 26911151.
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    68. Stereotactic probability and variability of speech arrest and anomia sites during stimulation mapping of the language dominant hemisphere. J Neurosurg. 2017 Jan; 126(1):114-121. PMID: 26894457.
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    69. STONE PLUS: Evaluation of Emergency Department Patients With Suspected Renal Colic, Using a Clinical Prediction Tool Combined With Point-of-Care Limited Ultrasonography. Ann Emerg Med. 2016 Apr; 67(4):439-48. PMID: 26747219.
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    70. Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. Oncotarget. 2015 Dec 15; 6(40):42468-77. PMID: 26646793.
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    71. Statistical considerations on prognostic models for glioma. Neuro Oncol. 2016 05; 18(5):609-23. PMID: 26657835.
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    72. Association of Diffusion and Anatomic Imaging Parameters with Survival for Patients with Newly Diagnosed Glioblastoma Participating in Two Different Clinical Trials. Transl Oncol. 2015 Dec; 8(6):446-55. PMID: 26692525.
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    73. The nuts and bolts of hypothesis testing. Neurooncol Pract. 2016 Sep; 3(3):139-144. Pugh SL, Molinaro A. PMID: 31386071.
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    74. A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. J Neurosurg. 2016 May; 124(5):1300-9. PMID: 26544781.
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    75. Comparative Sensitivity of Intraoperative Motor Evoked Potential Monitoring in Predicting Postoperative Neurologic Deficits: Nondegenerative versus Degenerative Myelopathy. Global Spine J. 2016 Aug; 6(5):452-8. PMID: 27433429.
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    76. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro Oncol. 2016 Apr; 18(4):557-64. PMID: 26449250.
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    77. DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors. Cancer Cell. 2015 Sep 14; 28(3):307-317. PMID: 26373278.
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    78. New initiative for Neuro-Oncology Practice: statistics for the practicing clinician. Neurooncol Pract. 2015 Dec; 2(4):161. Molinaro AM. PMID: 31386068.
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    79. Diagnostic tests: how to estimate the positive predictive value. Neurooncol Pract. 2015 Dec; 2(4):162-166. Molinaro AM. PMID: 31386059.
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    80. Surgical assessment of the insula. Part 2: validation of the Berger-Sanai zone classification system for predicting extent of glioma resection. J Neurosurg. 2016 Feb; 124(2):482-8. PMID: 26339856.
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    81. Neurocognitive Function in Newly Diagnosed Low-grade Glioma Patients Undergoing Surgical Resection With Awake Mapping Techniques. Neurosurgery. 2015 Sep; 77(3):371-9; discussion 379. PMID: 25930064.
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    82. Understanding inherited genetic risk of adult glioma - a review. Neurooncol Pract. 2016 Mar; 3(1):10-16. PMID: 26941959.
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    83. Impact of Timing of Concurrent Chemoradiation for Newly Diagnosed Glioblastoma: A Critical Review of Current Evidence. Neurosurgery. 2015 Aug; 62 Suppl 1:160-5. PMID: 26181937.
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    84. The Effect of Timing of Concurrent Chemoradiation in Patients With Newly Diagnosed Glioblastoma. Neurosurgery. 2015 Aug; 77(2):248-53; discussion 253. PMID: 25856113.
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    85. The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma. Neuro Oncol. 2016 Jan; 18(1):87-95. PMID: 26206774.
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    86. Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm. J Neurosurg. 2016 Jan; 124(1):163-74. Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW. PMID: 26140495.
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    87. Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med. 2015 Jun 25; 372(26):2499-508. PMID: 26061753.
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    88. Telomere maintenance and the etiology of adult glioma. Neuro Oncol. 2015 Nov; 17(11):1445-52. PMID: 26014050.
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    89. A probabilistic map of the human ventral sensorimotor cortex using electrical stimulation. J Neurosurg. 2015 Aug; 123(2):340-9. PMID: 25978714.
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    90. Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors. J Neurosurg. 2015 Aug; 123(2):373-86. Sneed PK, Mendez J, Vemer-van den Hoek JG, Seymour ZA, Ma L, Molinaro AM, Fogh SE, Nakamura JL, McDermott MW. PMID: 25978710.
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    91. Toward precision medicine in glioblastoma: the promise and the challenges. Neuro Oncol. 2015 Aug; 17(8):1051-63. PMID: 25934816.
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    92. CDKN2A loss is associated with shortened overall survival in lower-grade (World Health Organization Grades II-III) astrocytomas. J Neuropathol Exp Neurol. 2015 May; 74(5):442-52. PMID: 25853694.
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    93. Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period. J Neurosurg. 2015 Aug; 123(2):325-39. PMID: 25909573.
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    94. Indoor tanning and the MC1R genotype: risk prediction for basal cell carcinoma risk in young people. Am J Epidemiol. 2015 Jun 01; 181(11):908-16. PMID: 25858289.
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    95. Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment. Acta Neuropathol. 2015 Apr; 129(4):597-607. PMID: 25724300.
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    96. The genetics of splicing in neuroblastoma. Cancer Discov. 2015 Apr; 5(4):380-95. PMID: 25637275.
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    97. Survival and low-grade glioma: the emergence of genetic information. Neurosurg Focus. 2015 Jan; 38(1):E6. PMID: 25552286.
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    98. A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass. J Clin Neurosci. 2015 Jan; 22(1):155-60. PMID: 25481269.
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    99. Factors associated with failed focal neocortical epilepsy surgery. Neurosurgery. 2014 Dec; 75(6):648-5;discussion 655; quiz 656. PMID: 25181435.
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    100. Alcohol intake and early-onset basal cell carcinoma in a case-control study. Br J Dermatol. 2014 Dec; 171(6):1451-7. PMID: 25059635.
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    101. Accuracy of reduced-dose computed tomography for ureteral stones in emergency department patients. Ann Emerg Med. 2015 Feb; 65(2):189-98.e2. PMID: 25441242.
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    102. Comparison of ADC metrics and their association with outcome for patients with newly diagnosed glioblastoma being treated with radiation therapy, temozolomide, erlotinib and bevacizumab. J Neurooncol. 2015 Jan; 121(2):331-9. PMID: 25351579.
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    103. Pure germinomas of the central nervous system: treatment strategies and outcomes. J Neurooncol. 2014 Dec; 120(3):643-9. PMID: 25189788.
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    104. Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma. J Neurooncol. 2014 Nov; 120(2):353-60. PMID: 25106865.
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    105. Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case-control study. Eur J Cancer Prev. 2014 Jul; 23(4):296-302. PMID: 24841641.
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    106. A single-institution phase II trial of radiation, temozolomide, erlotinib, and bevacizumab for initial treatment of glioblastoma. Neuro Oncol. 2014 Jul; 16(7):984-90. PMID: 24637230.
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    107. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Nat Genet. 2014 Jul; 46(7):731-5. PMID: 24908248.
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    108. Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone--the STONE score: retrospective and prospective observational cohort studies. BMJ. 2014 Mar 26; 348:g2191. PMID: 24671981.
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    109. Phase II trial of 7 days on/7 days off temozolmide for recurrent high-grade glioma. Neuro Oncol. 2014 Sep; 16(9):1255-62. PMID: 24670608.
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    110. Effect of provider experience on clinician-performed ultrasonography for hydronephrosis in patients with suspected renal colic. Ann Emerg Med. 2014 Sep; 64(3):269-76. PMID: 24630203.
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    111. Characterization of metabolites in infiltrating gliomas using ex vivo ¹H high-resolution magic angle spinning spectroscopy. NMR Biomed. 2014 May; 27(5):578-93. PMID: 24596146.
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    112. Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease. J Neurooncol. 2014 Feb; 116(3):593-600. PMID: 24398617.
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    113. Gross total resection improves overall survival in children with choroid plexus carcinoma. J Neurooncol. 2014 Jan; 116(1):179-85. PMID: 24166581.
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    114. Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008. J Clin Neurosci. 2013 Nov; 20(11):1538-45. PMID: 23932422.
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    115. Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis. Neuro Oncol. 2013 Aug; 15(8):1041-7. PMID: 23733245.
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    116. Prevalence and clinical importance of alternative causes of symptoms using a renal colic computed tomography protocol in patients with flank or back pain and absence of pyuria. Acad Emerg Med. 2013 May; 20(5):470-8. PMID: 23672361.
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    117. The relative patient benefit of gross total resection in adult choroid plexus papillomas. J Clin Neurosci. 2013 Jun; 20(6):808-12. PMID: 23623658.
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    118. PDGFRA amplification is common in pediatric and adult high-grade astrocytomas and identifies a poor prognostic group in IDH1 mutant glioblastoma. Brain Pathol. 2013 Sep; 23(5):565-73. PMID: 23438035.
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    119. Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma. Anticancer Res. 2013 Mar; 33(3):755-62. PMID: 23482742.
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    120. Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme. Neuro Oncol. 2013 Apr; 15(4):480-9. PMID: 23393208.
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    121. Prognosis by tumor location in adults with spinal ependymomas. J Neurosurg Spine. 2013 Mar; 18(3):226-35. PMID: 23311515.
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    122. Prognosis by tumor location for pediatric spinal cord ependymomas. J Neurosurg Pediatr. 2013 Mar; 11(3):282-8. PMID: 23259510.
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    123. Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM. J Magn Reson Imaging. 2013 Aug; 38(2):388-400. PMID: 23281184.
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    124. RTOG 0211: a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients. Int J Radiat Oncol Biol Phys. 2013 Apr 01; 85(5):1206-11. PMID: 23182702.
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    125. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One. 2012; 7(8):e43339. PMID: 22937035.
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    126. Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging. Neuro Oncol. 2012 Jul; 14(7):942-54. PMID: 22711606.
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    127. A partitioning deletion/substitution/addition algorithm for creating survival risk groups. Biometrics. 2012 Dec; 68(4):1146-56. PMID: 22519965.
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    128. Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res. 2012 Apr 01; 72(7):1773-83. PMID: 22447568.
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    129. Stathmin expression and its relationship to microtubule-associated protein tau and outcome in breast cancer. Cancer. 2012 Oct 01; 118(19):4660-9. PMID: 22359235.
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    130. Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates. BMC Public Health. 2012 Feb 10; 12:118. PMID: 22324969.
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    131. Indoor tanning and risk of early-onset basal cell carcinoma. J Am Acad Dermatol. 2012 Oct; 67(4):552-62. PMID: 22153793.
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    132. Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma. J Invest Dermatol. 2012 Apr; 132(4):1272-9. PMID: 22158557.
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    133. Evaluation of prognostic and predictive value of microtubule associated protein tau in two independent cohorts. Breast Cancer Res. 2011 Nov 02; 13(5):R85. Baquero MT, Lostritto K, Gustavson MD, Bassi KA, Appia F, Camp RL, Molinaro AM, Harris LN, Rimm DL. PMID: 21888627.
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    134. Natural history and surgical management of incidentally discovered low-grade gliomas. J Neurosurg. 2012 Feb; 116(2):365-72. Potts MB, Smith JS, Molinaro AM, Berger MS. PMID: 21999317.
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    135. Power of data mining methods to detect genetic associations and interactions. Hum Hered. 2011; 72(2):85-97. PMID: 21934324.
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    136. Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes. Neurosurg Focus. 2011 Jul; 31(1):E3. Jahangiri A, Molinaro AM, Tarapore PE, Blevins L, Auguste KI, Gupta N, Kunwar S, Aghi MK. PMID: 21721868.
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    137. Optimal tumor sampling for immunostaining of biomarkers in breast carcinoma. Breast Cancer Res. 2011 May 18; 13(3):R51. PMID: 21592345.
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    138. Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables. Lab Invest. 2011 Aug; 91(8):1253-61. Bai Y, Tolles J, Cheng H, Siddiqui S, Gopinath A, Pectasides E, Camp RL, Rimm DL, Molinaro AM. PMID: 21519325.
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    139. Plasma markers for identifying patients with metastatic melanoma. Clin Cancer Res. 2011 Apr 15; 17(8):2417-25. PMID: 21487066.
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    140. Comparing the use of diagnostic imaging and receipt of carotid endarterectomy in elderly black and white stroke patients. J Stroke Cerebrovasc Dis. 2012 Oct; 21(7):600-6. Martin KD, Naert L, Goldstein LB, Kasl S, Molinaro AM, Lichtman JH. PMID: 21411337.
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    141. Methylated DNA immunoprecipitation genome-wide analysis. Methods Mol Biol. 2011; 791:113-23. PMID: 21913075.
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    142. A phase 2 trial of dasatinib in advanced melanoma. Cancer. 2011 May 15; 117(10):2202-8. PMID: 21523734.
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    143. A Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanoma. Oncogene. 2011 Mar 31; 30(13):1542-50. Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stern DF, Sznol M, Ariyan S, Lazova R, Halaban R, Kidd KK, Weidhaas JB, Slack FJ. PMID: 21119596.
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    144. Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis. J Natl Cancer Inst. 2010 May 05; 102(9):627-37. Kerlikowske K, Molinaro AM, Gauthier ML, Berman HK, Waldman F, Bennington J, Sanchez H, Jimenez C, Stewart K, Chew K, Ljung BM, Tlsty TD. PMID: 20427430.
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    145. partDSA: deletion/substitution/addition algorithm for partitioning the covariate space in prediction. Bioinformatics. 2010 May 15; 26(10):1357-63. Molinaro AM, Lostritto K, van der Laan M. PMID: 20375111.
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    146. STATISTICALBIOINFORMATICS: A GUIDE FOR LIFE AND BIOMEDICAL SCIENCE RESEARCHERS. Ed. Jae K. Lee. Statistical resampling for large screening data analysis such as classical resampling Bootstrapping, Markov chain Monte Carlo, and statistical simulation and validation strategies. 2010. Molinaro AM and Lostritto K. .
    147. Melanoma prognostic model using tissue microarrays and genetic algorithms. J Clin Oncol. 2009 Dec 01; 27(34):5772-80. Gould Rothberg BE, Berger AJ, Molinaro AM, Subtil A, Krauthammer MO, Camp RL, Bradley WR, Ariyan S, Kluger HM, Rimm DL. PMID: 19884546.
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    148. Genome-wide screen of promoter methylation identifies novel markers in melanoma. Genome Res. 2009 Aug; 19(8):1462-70. Koga Y, Pelizzola M, Cheng E, Krauthammer M, Sznol M, Ariyan S, Narayan D, Molinaro AM, Halaban R, Weissman SM. PMID: 19491193.
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    149. Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. PLoS One. 2009; 4(2):e4563. Halaban R, Krauthammer M, Pelizzola M, Cheng E, Kovacs D, Sznol M, Ariyan S, Narayan D, Bacchiocchi A, Molinaro A, Kluger Y, Deng M, Tran N, Zhang W, Picardo M, Enghild JJ. PMID: 19234609.
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    150. A preliminary mathematical model of skin dendritic cell trafficking and induction of t-cell immunity. Discrete and Continuous Dynamical Systems - Series B (DCDS-B): Special Issue on Mathematical Biology and Medicine. 2009; 12(2). Erickson AH, Wise A, Fleming S, Molinaro AM, Teboh-Ewungkem M, Baird M, Lateef Z, and de Pillis L.
    151. AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. Arch Pathol Lab Med. 2008 Nov; 132(11):1746-52. Gustavson MD, Molinaro AM, Tedeschi G, Camp RL, Rimm DL. PMID: 18976010.
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    152. Comparison of quantitative immunofluorescence with conventional methods for HER2/neu testing with respect to response to trastuzumab therapy in metastatic breast cancer. Arch Pathol Lab Med. 2008 Oct; 132(10):1635-47. Giltnane JM, Molinaro A, Cheng H, Robinson A, Turbin D, Gelmon K, Huntsman D, Rimm DL. PMID: 18834223.
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    153. MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment. Genome Res. 2008 Oct; 18(10):1652-9. Pelizzola M, Koga Y, Urban AE, Krauthammer M, Weissman S, Halaban R, Molinaro AM. PMID: 18765822.
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    154. High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer. Hum Pathol. 2008 Dec; 39(12):1835-43. Ghosh S, Sullivan CA, Zerkowski MP, Molinaro AM, Rimm DL, Camp RL, Chung GG. PMID: 18715621.
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    155. Classification of renal cell carcinoma based on expression of VEGF and VEGF receptors in both tumor cells and endothelial cells. Lab Invest. 2008 Sep; 88(9):962-72. Kluger HM, Siddiqui SF, Angeletti C, Sznol M, Kelly WK, Molinaro AM, Camp RL. PMID: 18626467.
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    156. Cross-Validated Bagged Learning. J Multivar Anal. 2008 Mar; 25(2):260-266. Petersen ML, Molinaro AM, Sinisi SE, van der Laan MJ. PMID: 19255599.
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    157. Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome. J Clin Oncol. 2007 Dec 01; 25(34):5418-25. Moeder CB, Giltnane JM, Harigopal M, Molinaro A, Robinson A, Gelmon K, Huntsman D, Camp RL, Rimm DL. PMID: 18048824.
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    158. Clinical and pathological findings in a HERDA-affected foal for 1.5 years of life. Vet Dermatol. 2007 Feb; 18(1):36-40. White SD, Affolter VK, Schultheiss PC, Ball BA, Wessel MT, Kass P, Molinaro AM, Bannasch DL, Ihrke PJ. PMID: 17222238.
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    159. Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population. Cancer Epidemiol Biomarkers Prev. 2006 Sep; 15(9):1641-6. Moore LE, Fung ET, McGuire M, Rabkin CC, Molinaro A, Wang Z, Zhang F, Wang J, Yip C, Meng XY, Pfeiffer RM. PMID: 16985025.
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    160. Survival ensembles. Biostatistics. 2006 Jul; 7(3):355-73. Hothorn T, Bühlmann P, Dudoit S, Molinaro A, van der Laan MJ. PMID: 16344280.
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    161. Prediction error estimation: a comparison of resampling methods. Bioinformatics. 2005 Aug 01; 21(15):3301-7. Molinaro AM, Simon R, Pfeiffer RM. PMID: 15905277.
      View in: PubMed   Mentions: 192     Fields:    
    162. Tree-based multivariate regression and density estimation with right-censored data. Journal of Multivariate Analysis. 2004; 90(1):154-177. Molinaro AM, Dudoit S, and van der Laan MJ.
    163. Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomy. J Natl Cancer Inst. 2003 Nov 19; 95(22):1692-702. Kerlikowske K, Molinaro A, Cha I, Ljung BM, Ernster VL, Stewart K, Chew K, Moore DH, Waldman F. PMID: 14625260.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    164. Loss-based estimation with cross-validation: Applications to microarray data analysis and motif finding. SIGKDD Explorations. 2003; 5(2):37-49. Dudoit S, van der Laan MJ, Keles¸ S, Molinaro AM, Sinisi S, and Teng SL.
    165. The apc/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: A mutational analysis. Cancer. 2002; 94(5):1421-7. Aust DE, Terdiman JP, Willenbucher RF, Chang CG, Molinaro AM, Baretton GB, Loehrs U, and Waldman FM.
    166. Loss of chromosome 16q in lobular carcinoma in situ. Hum Pathol. 2001 Mar; 32(3):292-6. Etzell JE, Devries S, Chew K, Florendo C, Molinaro A, Ljung BM, Waldman FM. PMID: 11274638.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    167. Altered Distribution of beta-catenin, and its binding proteins E-cadherin and APC, in Ulcerative Colitis-Related Colorectal Cancers. Modern Pathology. 2001; 14:29-39. Aust DE, Terdiman JP, Willenbucher RF, Chew K, Ferrell L, Florendo C, Molinaro AM, Baretton GB, Loehrs U, Waldman, FM.
    168. Chromosomal Alterations in Ulcerative Colitis-Related and Sporadic Colorectal Cancers by Comparative Genomic Hybridization. Human Pathology. 2000; 31(1):109-114. Aust DE, Willenbucher RF, Terdiman JP, Ferrell LD, Chang CG, Moore DH, Molinaro AM, Baretton GB, Loehrs U, Waldman FM.
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