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Shawn Hervey-Jumper, MD

Title(s)Associate Professor, Neurological Surgery
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Oakwood College, Huntsville, ALBS2001Biology
    The Ohio State University College of Medicine, Columbus, OHMD2006Medicine
    University of Michigan Comprehensive Cancer Center, Ann Arbor, MI2011Neuro-Oncology Research Fellow (PI- Xing Fan, PhD)
    University of Michigan Department of Neurological Surgery, Ann Arbor, MI2013Neurological Surgery
    University of California San Francisco Department of Neurosurgery, San Francisco, CA2014Clinical Neuro-Oncology Fellow
    Collapse Awards and Honors
    2005Alpha Omega Alpha Medical Honors Society
    2005Gold Humanism Honor Society
    2006Landacre Research Honors Society
    2006Phi Kappa Phi Honors Society
    2006Watchman Achievement Award, Alpha Omega Alpha Medical Honors Society
    2007National Scholars Honor Society
    2007Arnold G. Coran Teaching Award
    2010Ruben J Williams (RJW) Foundation Health Policy Scholar
    2011Wilder Penfield Research Award- Congress of Neurological Surgeons
    2011Neuro-Oncology Research Award- Neurosurgery Research and Education Foundation (NREF/AAcNS)
    2013Chandler-McGillicuddy Leadership Award
    2013Max Peet Teaching Award
    2014Ronald L. Bittner Award in Brain Tumor Research
    2016Alfred Taubman Medical Research Institute Emerging Scholar
    2017Harold Amos Fellow- RobertWood Johnson Foundation
    2017John A. Watson Faculty Scholar

    Collapse Overview 
    Collapse Overview
    Dr. Shawn Hervey-Jumper is a neurosurgeon with subspecialty focus on neuro-oncology. As an adult neurosurgeon and researcher his clinical efforts are focused on the surgical management of patients with intrinsic brain tumors such as glioma and brain metastasis within deep seated and functional regions of the brain responsible for language, motor, and cognition. His clinical practice also includes management of patients with meningiomas, and skull base brain tumors. Dr. Hervey-Jumper serves as Co-Director of the Sheri Sobrato Brisson Brain Cancer Survivorship Program which offers neurosurgery, neuro-oncology, physical medicine and rehabilitation, neuropsychology, and speech pathology multidisciplinary services to adult brain tumor patients.

    Collapse Research 
    Collapse Research Activities and Funding
    Intratumoral functional connectivity with implications on synaptogenesis and aphasia recovery in adult astrocytic WHO II-III glioma
    NINDS 1K08NS110919-01May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    IDH1 Mutant Glioma Model: Tumor Progression and Impact on Therapeutics
    NINDS P0523121Feb 1, 2018 - Feb 28, 2023
    Role: Co-Investigator
    NIH NCI SPORE Career Enhancement Award Language network repair and white matter recovery in WHO IV glioma
    NCI 5P50CA097257-15Oct 10, 2017 - Oct 1, 2019
    Role: Co-Investigator
    The consequences of brain irradiation on white matter repair and language pathways reorganization in adult glioma
    Robert Wood Johnson Foundation 74259Jul 1, 2017 - Jul 1, 2021
    Role: Principal Investigator
    Neurogenesis mediated Aphasia Recovery in Adult High Grade Glioma
    University of California San Francisco Dean's Diversity FundJul 1, 2017 - Jun 30, 2020
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Morshed RA, Young JS, Safaee M, Sankaran S, Berger MS, McDermott MW, Hervey-Jumper SL. Delirium risk factors and associated outcomes in a neurosurgical cohort: a case-control study. World Neurosurg. 2019 Mar 11. PMID: 30872201.
      View in: PubMed
    2. Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Sci Transl Med. 2019 Feb 13; 11(479). PMID: 30760578.
      View in: PubMed
    3. Hervey-Jumper SL, Berger MS. Insular glioma surgery: an evolution of thought and practice. J Neurosurg. 2019 Jan 01; 130(1):9-16. PMID: 30611160.
      View in: PubMed
    4. Morshed RA, Han SJ, Hervey-Jumper SL, Pekmezci M, Troncon I, Chang SM, Butowski NA, Berger MS. Molecular features and clinical outcomes in surgically treated low-grade diffuse gliomas in patients over the age of 60. J Neurooncol. 2019 Jan; 141(2):383-391. PMID: 30498891.
      View in: PubMed
    5. Hendriks EJ, Idema S, Hervey-Jumper SL, Bernat AL, Zwinderman AH, Barkhof F, Vandertop WP, Mandonnet E, Duffau H, Berger MS, De Witt Hamer PC. Preoperative Resectability Estimates of Nonenhancing Glioma by Neurosurgeons and a Resection Probability Map. Neurosurgery. 2018 Nov 10. PMID: 30423155.
      View in: PubMed
    6. Hervey-Jumper SL, Berger MS. Evidence for Improving Outcome Through Extent of Resection. Neurosurg Clin N Am. 2019 Jan; 30(1):85-93. PMID: 30470408.
      View in: PubMed
    7. Wang DD, Deng H, Hervey-Jumper SL, Molinaro AA, Chang EF, Berger MS. Seizure Outcome After Surgical Resection of Insular Glioma. Neurosurgery. 2018 Oct 01; 83(4):709-718. PMID: 29126238.
      View in: PubMed
    8. Morshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS. Perioperative outcomes following reoperation for recurrent insular gliomas. J Neurosurg. 2018 Sep 01; 1-7. PMID: 30239317.
      View in: PubMed
    9. Han SJ, Morshed RA, Troncon I, Jordan KM, Henry RG, Hervey-Jumper SL, Berger MS. Subcortical stimulation mapping of descending motor pathways for perirolandic gliomas: assessment of morbidity and functional outcome in 702 cases. J Neurosurg. 2018 Aug 01; 1-8. PMID: 30117770.
      View in: PubMed
    10. Franko LR, Hollon T, Linzey J, Roark C, Rajajee V, Sheehan K, Teig M, Hervey-Jumper S, Heth J, Orringer D, Williamson CA. Clinical Factors Associated With ICU-Specific Care Following Supratentoral Brain Tumor Resection and Validation of a Risk Prediction Score. Crit Care Med. 2018 Aug; 46(8):1302-1308. PMID: 29742589.
      View in: PubMed
    11. Morshed RA, Young JS, Hervey-Jumper SL. Sharpening the Surgeon's Knife: Value of Extent of Resection for Glioma in Molecular Age. World Neurosurg. 2018 09; 117:350-352. PMID: 29945007.
      View in: PubMed
    12. Morshed RA, Young JS, Han SJ, Hervey-Jumper SL, Berger MS. The transcortical equatorial approach for gliomas of the mesial temporal lobe: techniques and functional outcomes. J Neurosurg. 2018 Apr 01; 1-9. PMID: 29676697.
      View in: PubMed
    13. Jackson WC, Tsien CI, Junck L, Leung D, Hervey-Jumper S, Orringer D, Heth J, Wahl DR, Spratt DE, Cao Y, Lawrence TS, Kim MM. Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma. J Neurooncol. 2018 May; 138(1):155-162. PMID: 29388034.
      View in: PubMed
    14. Koschmann C, Farooqui Z, Kasaian K, Cao X, Zamler D, Stallard S, Venneti S, Hervey-Jumper S, Garton H, Muraszko K, Franchi L, Robertson PL, Leonard M, Opipari V, Castro MG, Lowenstein PR, Chinnaiyan A, Mody R. Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event. NPJ Precis Oncol. 2017; 1(1):32. PMID: 29872713.
      View in: PubMed
    15. Marini BL, Benitez LL, Zureick AH, Salloum R, Gauthier AC, Brown J, Wu YM, Robinson DR, Kumar C, Lonigro R, Vats P, Cao X, Kasaian K, Anderson B, Mullan B, Chandler B, Linzey JR, Camelo-Piragua SI, Venneti S, McKeever PE, McFadden KA, Lieberman AP, Brown N, Shao L, Leonard MAS, Junck L, McKean E, Maher CO, Garton HJL, Muraszko KM, Hervey-Jumper S, Mulcahy-Levy JM, Green A, Hoffman LM, Dorris K, Vitanza NA, Wang J, Schwartz J, Lulla R, Smiley NP, Bornhorst M, Haas-Kogan DA, Robertson PL, Chinnaiyan AM, Mody R, Koschmann C. Blood-brain barrier-adapted precision medicine therapy for pediatric brain tumors. Transl Res. 2017 10; 188:27.e1-27.e14. PMID: 28860053.
      View in: PubMed
    16. Nathan JK, Brezzell AL, Kim MM, Leung D, Wilkinson DA, Hervey-Jumper SL. Early initiation of chemoradiation following index craniotomy is associated with decreased survival in high-grade glioma. J Neurooncol. 2017 Nov; 135(2):325-333. PMID: 28744829.
      View in: PubMed
    17. Lau D, Hervey-Jumper SL, Han SJ, Berger MS. Intraoperative perception and estimates on extent of resection during awake glioma surgery: overcoming the learning curve. J Neurosurg. 2018 May; 128(5):1410-1418. PMID: 28731401.
      View in: PubMed
    18. Altshuler DB, Hervey-Jumper H, Hervey-Jumper SL. Surgical and Teaching Mission to Mongolia: Experience and Lessons. World Neurosurg. 2017 06; 102:668-670. PMID: 28366749.
      View in: PubMed
    19. Orringer DA, Pandian B, Niknafs YS, Hollon TC, Boyle J, Lewis S, Garrard M, Hervey-Jumper SL, Garton HJL, Maher CO, Heth JA, Sagher O, Wilkinson DA, Snuderl M, Venneti S, Ramkissoon SH, McFadden KA, Fisher-Hubbard A, Lieberman AP, Johnson TD, Xie XS, Trautman JK, Freudiger CW, Camelo-Piragua S. Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy. Nat Biomed Eng. 2017; 1. PMID: 28955599.
      View in: PubMed
    20. Wang AC, Owen JH, Abuzeid WM, Hervey-Jumper SL, He X, Gurrea M, Lin M, Altshuler DB, Keep RF, Prince ME, Carey TE, Fan X, McKean EL, Sullivan SE. STAT3 Inhibition as a Therapeutic Strategy for Chordoma. J Neurol Surg B Skull Base. 2016 Dec; 77(6):510-520. PMID: 27857879.
      View in: PubMed
    21. Hervey-Jumper SL, Berger MS. Maximizing safe resection of low- and high-grade glioma. J Neurooncol. 2016 11; 130(2):269-282. PMID: 27174197.
      View in: PubMed
    22. Berger MS, Hervey-Jumper S, Wick W. Astrocytic gliomas WHO grades II and III. Handb Clin Neurol. 2016; 134:345-60. PMID: 26948365.
      View in: PubMed
    23. Caverzasi E, Hervey-Jumper SL, Jordan KM, Lobach IV, Li J, Panara V, Racine CA, Sankaranarayanan V, Amirbekian B, Papinutto N, Berger MS, Henry RG. Identifying preoperative language tracts and predicting postoperative functional recovery using HARDI q-ball fiber tractography in patients with gliomas. J Neurosurg. 2016 07; 125(1):33-45. PMID: 26654181.
      View in: PubMed
    24. Lau D, Hervey-Jumper SL, Chang S, Molinaro AM, McDermott MW, Phillips JJ, Berger MS. A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. J Neurosurg. 2016 May; 124(5):1300-9. PMID: 26544781.
      View in: PubMed
    25. Southwell DG, Hervey-Jumper SL, Perry DW, Berger MS. Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex. J Neurosurg. 2016 May; 124(5):1460-9. PMID: 26544767.
      View in: PubMed
    26. Hervey-Jumper SL, Berger MS. Technical nuances of awake brain tumor surgery and the role of maximum safe resection. J Neurosurg Sci. 2015 Dec; 59(4):351-60. PMID: 26394241.
      View in: PubMed
    27. Benet A, Hervey-Jumper SL, Sánchez JJ, Lawton MT, Berger MS. Surgical assessment of the insula. Part 1: surgical anatomy and morphometric analysis of the transsylvian and transcortical approaches to the insula. J Neurosurg. 2016 Feb; 124(2):469-81. PMID: 26339854.
      View in: PubMed
    28. Hervey-Jumper SL, Li J, Osorio JA, Lau D, Molinaro AM, Benet A, Berger MS. Surgical assessment of the insula. Part 2: validation of the Berger-Sanai zone classification system for predicting extent of glioma resection. J Neurosurg. 2016 Feb; 124(2):482-8. PMID: 26339856.
      View in: PubMed
    29. Hervey-Jumper SL, Li J, Lau D, Molinaro AM, Perry DW, Meng L, Berger MS. Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period. J Neurosurg. 2015 Aug; 123(2):325-39. PMID: 25909573.
      View in: PubMed
    30. Hervey-Jumper SL, Berger MS. In reply: Reoperation for recurrent high-grade glioma: does tumor genetics play a role? Neurosurgery. 2015 Apr; 76(4):E497. PMID: 25635894.
      View in: PubMed
    31. Hollon T, Hervey-Jumper SL, Sagher O, Orringer DA. Advances in the Surgical Management of Low-Grade Glioma. Semin Radiat Oncol. 2015 Jul; 25(3):181-8. PMID: 26050588; PMCID: PMC4460567.
    32. Junck L, Hervey-Jumper SL, Sagher O. Resection of gliomas around language areas: can fMRI contribute? Neurology. 2015 Feb 10; 84(6):550-1. PMID: 25589665.
      View in: PubMed
    33. Hervey-Jumper SL, Park P. Examining the cost-effectiveness of 2-level cervical total disc replacement. JAMA Surg. 2014 Dec; 149(12):1239. PMID: 25317585.
      View in: PubMed
    34. Hervey-Jumper SL, Berger MS. Reoperation for recurrent high-grade glioma: a current perspective of the literature. Neurosurgery. 2014 Nov; 75(5):491-9; discussion 498-9. PMID: 24991712.
      View in: PubMed
    35. Lau D, Moon DH, Park P, Hervey-Jumper S, McKeever PE, Orringer DA. Radiation-induced intradural malignant peripheral nerve sheath tumor of the cauda equina with diffuse leptomeningeal metastasis. J Neurosurg Spine. 2014 Nov; 21(5):719-26. PMID: 25216401.
      View in: PubMed
    36. Osorio JA, Hervey-Jumper SL, Walsh KM, Clarke JL, Butowski NA, Prados MD, Berger MS. Familial gliomas: cases in two pairs of brothers. J Neurooncol. 2015 Jan; 121(1):135-40. PMID: 25208478.
      View in: PubMed
    37. Apkarian AO, Hervey-Jumper SL, Trobe JD. Cerebrospinal fluid leak presenting as oculorrhea after blunt orbitocranial trauma. J Neuroophthalmol. 2014 Sep; 34(3):271-3. PMID: 24621864.
      View in: PubMed
    38. Hervey-Jumper SL, Breshears J, Berger MS. Gelfoam scaffold for vein prolapse during brain tumor surgery. World Neurosurg. 2014 Nov; 82(5):912.e11-3. PMID: 25118058.
      View in: PubMed
    39. Hervey-Jumper SL, Garton HJ, Lau D, Altshuler D, Quint DJ, Robertson PL, Muraszko KM, Maher CO. Differences in vascular endothelial growth factor receptor expression and correlation with the degree of enhancement in medulloblastoma. J Neurosurg Pediatr. 2014 Aug; 14(2):121-8. PMID: 24905841.
      View in: PubMed
    40. Hervey-Jumper SL, Berger MS. Role of surgical resection in low- and high-grade gliomas. Curr Treat Options Neurol. 2014 Apr; 16(4):284. PMID: 24595756.
      View in: PubMed
    41. Hervey-Jumper SL, Singla N, Gebarski SS, Robertson P, Maher CO. Diffuse pontine lesions in children with neurofibromatosis type 1: making a case for unidentified bright objects. Pediatr Neurosurg. 2013; 49(1):55-9. PMID: 24192157.
      View in: PubMed
    42. VanderVeen N, Paran C, Krasinkiewicz J, Zhao L, Palmer D, Hervey-Jumper S, Ng P, Lowenstein PR, Castro MG. Effectiveness and preclinical safety profile of doxycycline to be used "off-label" to induce therapeutic transgene expression in a phase I clinical trial for glioma. Hum Gene Ther Clin Dev. 2013 Sep; 24(3):116-26. PMID: 24007469; PMCID: PMC4003468.
    43. Hervey-Jumper SL, Wang AC, Yates AN, Robertson PL, Muraszko KM, Garton HJ, Blaivas M. 8-year-old boy with progressive headache. Brain Pathol. 2013 Sep; 23(5):601-2. PMID: 23937593.
      View in: PubMed
    44. Hervey-Jumper SL, Altshuler DB, Wang AC, He X, Maher CO, Robertson PL, Garton HJ, Fan X, Muraszko KM, Camelo-Piragua S. The role of CD133+ cells in a recurrent embryonal tumor with abundant neuropil and true rosettes (ETANTR). Brain Pathol. 2014 Jan; 24(1):45-51. PMID: 23865520; PMCID: PMC3867594.
    45. Pabaney A, Hervey-Jumper SL, Domino J, Maher CO, Yang LJ. Macrovascular decompression of the median nerve for posttraumatic neuralgic limb pain. J Neurosurg Pediatr. 2013 Sep; 12(3):270-3. PMID: 23829379.
      View in: PubMed
    46. Hervey-Jumper SL, Maher CO. Is insurance status a modifiable factor in brain tumor treatment outcomes?: comment on "Postoperative mortality after surgery for brain tumors by patient insurance status in the United States". Arch Surg. 2012 Nov; 147(11):1025. PMID: 23165617.
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    47. Srinivasan S, Benneyworth B, Garton HJ, Hervey-Jumper SL, Raimer PL, Odetola FO, Han YY. Intracranial pressure/cerebral perfusion pressure-targeted management of life-threatening intracranial hypertension complicating diabetic ketoacidosis-associated cerebral edema: a case report. Pediatr Emerg Care. 2012 Jul; 28(7):696-8. PMID: 22766587.
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    48. Hervey-Jumper SL, McKeever PE, Gebarski SS, Muraszko KM, Maher CO. Spontaneous resolution of an infantile hemangioma in a dorsal root ganglion. Neurosurg Focus. 2011 Dec; 31(6):E16. PMID: 22133174.
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    49. Murphy KM, Rasmussen L, Hervey-Jumper SL, Justice D, Nelson VS, Yang LJ. An assessment of the compliance and utility of a home exercise DVD for caregivers of children and adolescents with brachial plexus palsy: a pilot study. PM R. 2012 Mar; 4(3):190-7. PMID: 22088854.
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    50. Hervey-Jumper SL, Justice D, Vanaman MM, Nelson VS, Yang LJ. Torticollis associated with neonatal brachial plexus palsy. Pediatr Neurol. 2011 Nov; 45(5):305-10. PMID: 22000310.
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    51. Pritchett CV, Hervey-Jumper SL, Aliu O, Hayanga AJ. Legislating change in surgical residency. Arch Surg. 2011 Aug; 146(8):972-4. PMID: 21844439.
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    52. Hervey-Jumper SL, Cohen-Gadol AA, Maher CO. Neurosurgical management of congenital malformations of the brain. Neuroimaging Clin N Am. 2011 Aug; 21(3):705-17, ix. PMID: 21807319.
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    53. Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, He X, Hervey-Jumper SL, Heth JA, Muraszko KM, DiMeco F, Vescovi AL, Fan X. Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res. 2011 Sep 15; 71(18):6061-72. PMID: 21788346; PMCID: PMC3355476.
    54. Hervey-Jumper SL, Garton HJ, Wetjen NM, Maher CO. Neurosurgical management of congenital malformations and inherited disease of the spine. Neuroimaging Clin N Am. 2011 Aug; 21(3):719-31, ix. PMID: 21807320.
      View in: PubMed
    55. Hervey-Jumper SL, Annich GM, Yancon AR, Garton HJ, Muraszko KM, Maher CO. Neurological complications of extracorporeal membrane oxygenation in children. J Neurosurg Pediatr. 2011 Apr; 7(4):338-44. PMID: 21456903.
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    56. Hervey-Jumper SL, Ghori A, Ziewacz JE, McKeever PE, Chandler WF. Langerhans cell histiocytosis of the optic chiasm: case report. Neurosurgery. 2011 Feb; 68(2):E556-61. PMID: 21135729.
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    57. Hervey-Jumper SL, Jumper M, Blaivas M, Parmar HA, Robertson PL, Maher CO. Primary diffuse leptomeningeal oligodendroglioma. Pediatr Neurosurg. 2010; 46(4):326-8. PMID: 21196802.
      View in: PubMed
    58. Park P, Wang AC, Sangala JR, Kim SM, Hervey-Jumper S, Than KD, Farokhrani A, Lamarca F. Impact of multimodal intraoperative monitoring during correction of symptomatic cervical or cervicothoracic kyphosis. J Neurosurg Spine. 2011 Jan; 14(1):99-105. PMID: 21142458.
      View in: PubMed
    59. Enguita-Germán M, Gurrea M, Schiapparelli P, Zhu TS, Crowley JG, Hamm LL, Costello MA, He X, Talsma CE, Flack CG, Hervey-Jumper SL, Heth JA, Muraszko KM, Rey JA, Fan X, Castresana JS. KIT expression and methylation in medulloblastoma and PNET cell lines and tumors. J Neurooncol. 2011 Jun; 103(2):247-53. PMID: 20853134.
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    60. Vanaman MJ, Hervey-Jumper SL, Maher CO. Pediatric and inherited neurovascular diseases. Neurosurg Clin N Am. 2010 Jul; 21(3):427-41. PMID: 20561493.
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    61. Hervey-Jumper SL, Ghori AK, Quint DJ, Marentette LJ, Maher CO. Cerebrospinal fluid leak with recurrent meningitis following tonsillectomy. J Neurosurg Pediatr. 2010 Mar; 5(3):302-5. PMID: 20192650.
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    62. Hervey-Jumper SL, Ziewacz JE, Heth JA, Sullivan SE. Frontal-to-temporal horn shunt as treatment for temporal horn entrapment. J Neurosurg. 2010 Feb; 112(2):410-3. PMID: 19408983.
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