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Manish Aghi, MD, PhD, MAS

Title(s)Professor, Neurological Surgery
SchoolSchool of Medicine
Phone415-353-3998
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    Stanford University , Stanford, CA B.S.1993Biological Sciences
    Stanford University , Stanford, CAM.S.1993Biological Sciences
    Harvard University, Boston, MA M.D.2000School of Medicine
    Harvard University, Boston, MA Ph.D.2000Neuroscience

    Collapse Overview 
    Collapse Overview
    Manish Aghi is a neurosurgeon and scientist at University of California, San Francisco (UCSF). He completed his MD-PhD degrees through the MSTP program at Harvard Medical School, followed by neurological surgery residency and postdoctoral training at Massachusetts General Hospital. He is currently faculty in the department of neurological surgery and graduate division of biomedical sciences, as well as a principal investigator in the Brain Tumor Research Center at UCSF. His clinical practice is focused on the surgical management of brain and skull base tumors, with special emphasis on intraoperative brain mapping for glioma surgery, pituitary tumor surgery, and minimally invasive endoscopic skull base surgery. Work in the Aghi laboratory has been funded by NIH and private foundations since 2008 and is focused on the role of tumor-microenvironment interactions in driving aggressive biology and therapeutic resistance in benign and malignant brain tumors like pituitary adenomas and gliomas. Active areas of research include the role of tumor-associated macrophages in glioblastoma growth, whole genome sequencing of pituitary adenomas, metabolic changes occurring after anti-angiogenic therapy in glioblastoma, and the role of a tyrosine kinase-integrin receptor complex in driving invasive resistance in glioblastoma. He serves as PI on multiple industry sponsored and investigator-initiated phase I-II clinical trials comparing immunotherapy versus anti-angiogenic theray of recurrent glioblastoma, as well as investigating convection-enhanced delivery of oncolytic viruses and nanoliposomal chemotherapy to recurrent glioblastoma.

    Collapse Research 
    Collapse Research Activities and Funding
    Modeling and druggable-genome screening of glioblastoma invasion using regional biopsy-guided biomaterials systems
    NIH/NCI R01CA227136Sep 17, 2018 - Aug 31, 2023
    Role: Principal Investigator
    Tumor cell and microenvironment changes causing antiangiogenic therapy resistance
    NIH/NINDS R01NS079697Sep 30, 2013 - Jun 30, 2022
    Role: Principal Investigator
    Characterizing and Targeting Tumoral Factors Recruiting Perivascular Progenitors
    NIH/NINDS K02NS064167Jul 1, 2009 - Jun 30, 2014
    Role: Principal Investigator

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    Collapse Twitter
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Aghi MK, Blevins LS. Introduction to Pituitary Adenomas. Neurosurg Clin N Am. 2019 Oct; 30(4):xiii. PMID: 31471060.
      View in: PubMed
    2. Wang L, Babikir H, Muller S, Yagnik G, Shamardani K, Catalan F, Kohanbash G, Alvarado B, Di Lullo E, Kriegstein A, Shah S, Wadhwa H, Chang SM, Philips JJ, Aghi MK, Diaz AA. The phenotypes of proliferating glioblastoma cells reside on a single axis of variation. Cancer Discov. 2019 Sep 25. PMID: 31554641.
      View in: PubMed
    3. Jahangiri A, Flanigan PM, Arnush M, Chandra A, Rick JW, Choi S, Chou A, Berger MS, Aghi MK. From bench to bedside: trends in National Institutes of Health funding for neurosurgeons from 1991 to 2015. J Neurosurg. 2019 Aug 30; 1-10. PMID: 31470404.
      View in: PubMed
    4. Chandra A, Rick J, Yagnik G, Aghi MK. Autophagy as a Mechanism for Anti-Angiogenic Therapy Resistance. Semin Cancer Biol. 2019 Aug 28. PMID: 31472232.
      View in: PubMed
    5. Rick JW, Chandra A, Dalle Ore C, Nguyen AT, Yagnik G, Aghi MK. Fibronectin in malignancy: Cancer-specific alterations, protumoral effects, and therapeutic implications. Semin Oncol. 2019 Aug 27. PMID: 31488338.
      View in: PubMed
    6. Butowski NA, Bringas JR, Bankiewicz KS, Aghi MK. Editorial. Chronic convection-enhanced delivery: the next frontier in regional drug infusion for glioblastoma. J Neurosurg. 2019 Aug 02; 1-3. PMID: 31374552.
      View in: PubMed
    7. Rick JW, Shahin M, Chandra A, Dalle Ore C, Yue JK, Nguyen A, Yagnik G, Sagar S, Arfaie S, Aghi MK. Systemic therapy for brain metastases. Crit Rev Oncol Hematol. 2019 Jul 22; 142:44-50. PMID: 31357143.
      View in: PubMed
    8. Faltermeier CM, Magill ST, Blevins LS, Aghi MK. Molecular Biology of Pituitary Adenomas. Neurosurg Clin N Am. 2019 Oct; 30(4):391-400. PMID: 31471046.
      View in: PubMed
    9. Yagnik G, Rutkowski M, Shah SS, Aghi MK. Correction: Stratifying nonfunctional pituitary adenomas into two groups distinguished by macrophage subtypes. Oncotarget. 2019 Jul 02; 10(42):4350. PMID: 31303968.
      View in: PubMed
    10. Chandra A, Young JS, Dalle Ore C, Dayani F, Lau D, Wadhwa H, Rick JW, Nguyen AT, McDermott MW, Berger MS, Aghi MK. Insurance type impacts the economic burden and survival of patients with newly diagnosed glioblastoma. J Neurosurg. 2019 Jun 21; 1-11. PMID: 31226687.
      View in: PubMed
    11. Dalle Ore CL, Magill ST, Yen AJ, Shahin MN, Lee DS, Lucas CG, Chen WC, Viner JA, Aghi MK, Theodosopoulos PV, Raleigh DR, Villanueva-Meyer JE, McDermott MW. Meningioma metastases: incidence and proposed screening paradigm. J Neurosurg. 2019 04 05; 1-9. PMID: 30952122.
      View in: PubMed
    12. Lee TJ, Nair M, Banasavadi-Siddegowda Y, Liu J, Nallanagulagari T, Jaime-Ramirez AC, Guo JY, Quadri H, Zhang J, Bockhorst KH, Aghi MK, Carbonell WS, Kaur B, Yoo JY. Enhancing Therapeutic Efficacy of Oncolytic Herpes Simplex Virus-1 with Integrin ß1 Blocking Antibody OS2966. Mol Cancer Ther. 2019 Jun; 18(6):1127-1136. PMID: 30926634.
      View in: PubMed
    13. Yagnik G, Rutowski MJ, Shah SS, Aghi MK. Stratifying nonfunctional pituitary adenomas into two groups distinguished by macrophage subtypes. Oncotarget. 2019 Mar 15; 10(22):2212-2223. PMID: 31040912.
      View in: PubMed
    14. Young JS, Dayani F, Morshed RA, Okada H, Aghi MK. Immunotherapy for High Grade Gliomas: A Clinical Update and Practical Considerations for Neurosurgeons. World Neurosurg. 2019 Jan 21. PMID: 30677574.
      View in: PubMed
    15. Flanigan PM, Jahangiri A, Weinstein D, Dayani F, Chandra A, Kanungo I, Choi S, Sankaran S, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications. Neurosurgery. 2018 12 01; 83(6):1161-1172. PMID: 29462362.
      View in: PubMed
    16. Dalle Ore CL, Chandra A, Rick J, Lau D, Shahin M, Nguyen AT, McDermott M, Berger MS, Aghi MK. Presence of Histopathological Treatment Effects at Resection of Recurrent Glioblastoma: Incidence and Effect on Outcome. Neurosurgery. 2018 Nov 16. PMID: 30445646.
      View in: PubMed
    17. Magill ST, Dalle Ore CL, Diaz MA, Jalili DD, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Surgical outcomes after reoperation for recurrent non-skull base meningiomas. J Neurosurg. 2018 Nov 01; 1-9. PMID: 30544357.
      View in: PubMed
    18. Flanigan PM, Jahangiri A, Golubovsky JL, Karnuta JM, May FJ, Berger MS, Aghi MK. A cross-sectional study of neurosurgical department chairs in the United States. J Neurosurg. 2018 11 01; 129(5):1342-1348. PMID: 29303441.
      View in: PubMed
    19. López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 Jan; 137(1):139-150. PMID: 30196423.
      View in: PubMed
    20. Rick J, Jahangiri A, Flanigan PM, Chandra A, Kunwar S, Blevins L, Aghi MK. Growth hormone and prolactin-staining tumors causing acromegaly: a retrospective review of clinical presentations and surgical outcomes. J Neurosurg. 2018 Sep 01; 1-7. PMID: 30215558.
      View in: PubMed
    21. Wei L, Burke J, Benet A, Aghi M, Gurrola J, El-Sayed I. Endoscope Image Capture System with Mirrorless Camera. J Neurol Surg B Skull Base. 2019 Feb; 80(1):79-81. PMID: 30733905.
      View in: PubMed
    22. Sagar S, Rick J, Chandra A, Yagnik G, Aghi MK. Functional brain mapping: overview of techniques and their application to neurosurgery. Neurosurg Rev. 2019 Sep; 42(3):639-647. PMID: 30006663.
      View in: PubMed
    23. Safaee MM, Morshed RA, Spatz J, Sankaran S, Berger MS, Aghi MK. Interfacility neurosurgical transfers: an analysis of nontraumatic inpatient and emergency department transfers with implications for improvements in care. J Neurosurg. 2018 Jul 01; 1-9. PMID: 30074453.
      View in: PubMed
    24. Chandra A, Rick JW, Dalle Ore C, Lau D, Nguyen AT, Carrera D, Bonte A, Molinaro AM, Theodosopoulos PV, McDermott MW, Berger MS, Aghi MK. Disparities in health care determine prognosis in newly diagnosed glioblastoma. Neurosurg Focus. 2018 Jun; 44(6):E16. PMID: 29852776.
      View in: PubMed
    25. Dayani F, Young JS, Bonte A, Chang EF, Theodosopoulos P, McDermott MW, Berger MS, Aghi MK. Safety and outcomes of resection of butterfly glioblastoma. Neurosurg Focus. 2018 06; 44(6):E4. PMID: 29852771.
      View in: PubMed
    26. Magill ST, Shahin MN, Lucas CG, Yen AJ, Lee DS, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Surgical Outcomes, Complications, and Management Strategies for Foramen Magnum Meningiomas. J Neurol Surg B Skull Base. 2019 Feb; 80(1):1-9. PMID: 30733894.
      View in: PubMed
    27. Magill ST, Lee DS, Yen AJ, Lucas CG, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Surgical outcomes after reoperation for recurrent skull base meningiomas. J Neurosurg. 2018 May 04; 130(3):876-883. PMID: 29726777.
      View in: PubMed
    28. Dalle Ore CL, Ames CP, Magill ST, Deviren V, Aghi MK, Lau D. Initial Experience with Intraoperative Phosphorous-32 Brachytherapy During Resection of Malignant Spinal Tumors. World Neurosurg. 2018 07; 115:e785-e793. PMID: 29702311.
      View in: PubMed
    29. Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. 2018 05 14; 33(5):874-889.e7. PMID: 29681511.
      View in: PubMed
    30. Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF. Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. Neuro Oncol. 2018 04 09; 20(5):632-641. PMID: 29077933.
      View in: PubMed
    31. Chen WC, Magill ST, Wu A, Vasudevan HN, Morin O, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Braunstein SE, Raleigh DR. Histopathological features predictive of local control of atypical meningioma after surgery and adjuvant radiotherapy. J Neurosurg. 2018 Apr 06; 130(2):443-450. PMID: 29624151.
      View in: PubMed
    32. Magill ST, Rick JW, Chen WC, Haase DA, Raleigh DR, Aghi MK, Theodosopoulos PV, McDermott MW. Petrous Face Meningiomas: Classification, Clinical Syndromes, and Surgical Outcomes. World Neurosurg. 2018 Jun; 114:e1266-e1274. PMID: 29626689.
      View in: PubMed
    33. Magill ST, Young JS, Chae R, Aghi MK, Theodosopoulos PV, McDermott MW. Relationship between tumor location, size, and WHO grade in meningioma. Neurosurg Focus. 2018 04; 44(4):E4. PMID: 29606048.
      View in: PubMed
    34. Magill ST, Morshed RA, Lucas CG, Aghi MK, Theodosopoulos PV, Berger MS, de Divitiis O, Solari D, Cappabianca P, Cavallo LM, McDermott MW. Tuberculum sellae meningiomas: grading scale to assess surgical outcomes using the transcranial versus transsphenoidal approach. Neurosurg Focus. 2018 04; 44(4):E9. PMID: 29606045.
      View in: PubMed
    35. Chen WC, Hara J, Magill ST, Wu A, Aghi MK, Theodosopoulos PV, Perry A, McDermott MW, Sneed PK, Raleigh DR, Braunstein SE. Salvage therapy outcomes for atypical meningioma. J Neurooncol. 2018 Jun; 138(2):425-433. PMID: 29480505.
      View in: PubMed
    36. Rick J, Chandra A, Aghi MK. Tumor treating fields: a new approach to glioblastoma therapy. J Neurooncol. 2018 May; 137(3):447-453. PMID: 29349613.
      View in: PubMed
    37. Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma. Neurosurgery. 2018 Jan 01; 82(1):64-75. PMID: 28475720.
      View in: PubMed
    38. Müller S, Kohanbash G, Liu SJ, Alvarado B, Carrera D, Bhaduri A, Watchmaker PB, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim DA, Aghi M, Okada H, Diaz A. Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment. Genome Biol. 2017 Dec 20; 18(1):234. PMID: 29262845.
      View in: PubMed
    39. Rutkowski MJ, Aghi MK. Medical versus surgical treatment of prolactinomas: an analysis of treatment outcomes. Expert Rev Endocrinol Metab. 2018 01; 13(1):25-33. PMID: 30063440.
      View in: PubMed
    40. Flanigan PM, Jahangiri A, Kuang R, Truong A, Choi S, Chou A, Rick JW, Chang SM, Molinaro AM, McDermott MW, Berger MS, Aghi MK. Improved Survival with Decreased Wait Time to Surgery in Glioblastoma Patients Presenting with Seizure. Neurosurgery. 2017 Nov 01; 81(5):824-833. PMID: 28541497.
      View in: PubMed
    41. Flis DW, Burke JF, Benet A, Theodosopoulos P, Aghi M, El-Sayed IH. The Endoscopic Buccal Fat Pad Flap for Closure of Skull Base Defects: A Report of 5 Cases. World Neurosurg. 2018 Feb; 110:e42-e45. PMID: 28987843.
      View in: PubMed
    42. Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, Mascharak S, De Lay M, Imber B, Park CC, Matsumoto K, Lu K, Bergers G, Sali A, Weiss WA, Aghi MK. Cross-activating c-Met/ß1 integrin complex drives metastasis and invasive resistance in cancer. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):E8685-E8694. PMID: 28973887.
      View in: PubMed
    43. Kwiatkowski SC, Guerrero PA, Hirota S, Chen Z, Morales JE, Aghi M, McCarty JH. Neuropilin-1 modulates TGFß signaling to drive glioblastoma growth and recurrence after anti-angiogenic therapy. PLoS One. 2017; 12(9):e0185065. PMID: 28938007.
      View in: PubMed
    44. Rutkowski MJ, Kunwar S, Blevins L, Aghi MK. Surgical intervention for pituitary apoplexy: an analysis of functional outcomes. J Neurosurg. 2018 08; 129(2):417-424. PMID: 28946177.
      View in: PubMed
    45. Chan AK, Han SJ, Choy W, Beleford D, Aghi MK, Berger MS, Shieh JT, Bollen AW, Perry A, Phillips JJ, Butowski N, Solomon DA. Familial melanoma-astrocytoma syndrome: synchronous diffuse astrocytoma and pleomorphic xanthoastrocytoma in a patient with germline CDKN2A/B deletion and a significant family history. Clin Neuropathol. 2017 Sep/Oct; 36(5):213-221. PMID: 28699883.
      View in: PubMed
    46. Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. In Reply: Factors Predicting Recurrence After Resection of Clival Chordoma Using Variable Surgical Approaches and Radiation Modalities. Neurosurgery. 2017 08 01; 81(2):E32. PMID: 28379552.
      View in: PubMed
    47. Vasudevan HN, Raleigh DR, Johnson J, Garsa AA, Theodosopoulos PV, Aghi MK, Ames C, McDermott MW, Barani IJ, Braunstein SE. Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy. Front Surg. 2017; 4:35. PMID: 28691010.
      View in: PubMed
    48. Rutkowski MJ, Alward RM, Chen R, Wagner J, Jahangiri A, Southwell DG, Kunwar S, Blevins L, Lee H, Aghi MK. Atypical pituitary adenoma: a clinicopathologic case series. J Neurosurg. 2018 04; 128(4):1058-1065. PMID: 28598278.
      View in: PubMed
    49. Rick JW, Jahangiri A, Flanigan PM, Aghi MK. Patients cured of acromegaly do not experience improvement of their skull deformities. Pituitary. 2017 Apr; 20(2):292-294. PMID: 27590786.
      View in: PubMed
    50. Castro BA, Imber BS, Chen R, McDermott MW, Aghi MK. Ventriculoperitoneal Shunting for Glioblastoma: Risk Factors, Indications, and Efficacy. Neurosurgery. 2017 03 01; 80(3):421-430. PMID: 27218235.
      View in: PubMed
    51. Castro BA, Flanigan P, Jahangiri A, Hoffman D, Chen W, Kuang R, De Lay M, Yagnik G, Wagner JR, Mascharak S, Sidorov M, Shrivastav S, Kohanbash G, Okada H, Aghi MK. Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy. Oncogene. 2017 06 29; 36(26):3749-3759. PMID: 28218903.
      View in: PubMed
    52. Yagnik G, Jahangiri A, Chen R, Wagner JR, Aghi MK. Role of a p53 polymorphism in the development of nonfunctional pituitary adenomas. Mol Cell Endocrinol. 2017 05 05; 446:81-90. PMID: 28214592.
      View in: PubMed
    53. Kuang R, Jahangiri A, Mascharak S, Nguyen A, Chandra A, Flanigan PM, Yagnik G, Wagner JR, De Lay M, Carrera D, Castro BA, Hayes J, Sidorov M, Garcia JLI, Eriksson P, Ronen S, Phillips J, Molinaro A, Koliwad S, Aghi MK. GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance. JCI Insight. 2017 01 26; 2(2):e88815. PMID: 28138554.
      View in: PubMed
    54. Winkler EA, Birk H, Safaee M, Yue JK, Burke JF, Viner JA, Pekmezci M, Perry A, Aghi MK, Berger MS, McDermott MW. Erratum to: Surgical resection of fourth ventricular ependymomas: case series and technical nuances. J Neurooncol. 2017 01; 131(2):423. PMID: 28039568.
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    55. Imber BS, Kanungo I, Braunstein S, Barani IJ, Fogh SE, Nakamura JL, Berger MS, Chang EF, Molinaro AM, Cabrera JR, McDermott MW, Sneed PK, Aghi MK. Indications and Efficacy of Gamma Knife Stereotactic Radiosurgery for Recurrent Glioblastoma: 2 Decades of Institutional Experience. Neurosurgery. 2017 Jan 01; 80(1):129-139. PMID: 27428784.
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    56. Müller S, Liu SJ, Di Lullo E, Malatesta M, Pollen AA, Nowakowski TJ, Kohanbash G, Aghi M, Kriegstein AR, Lim DA, Diaz A. Single-cell sequencing maps gene expression to mutational phylogenies in PDGF- and EGF-driven gliomas. Mol Syst Biol. 2016 Nov 25; 12(11):889. PMID: 27888226.
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    57. Winkler EA, Birk H, Safaee M, Yue JK, Burke JF, Viner JA, Pekmezci M, Perry A, Aghi MK, Berger MS, McDermott MW. Surgical resection of fourth ventricular ependymomas: case series and technical nuances. J Neurooncol. 2016 11; 130(2):341-349. PMID: 27778210.
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    58. Lucas JW, Bodach ME, Tumialan LM, Oyesiku NM, Patil CG, Litvack Z, Aghi MK, Zada G. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Primary Management of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E533-5. PMID: 27635961.
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    59. Sheehan J, Lee CC, Bodach ME, Tumialan LM, Oyesiku NM, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Management of Patients With Residual or Recurrent Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E539-40. PMID: 27635963.
      View in: PubMed
    60. Chen CC, Carter BS, Wang R, Patel KS, Hess C, Bodach ME, Tumialan LM, Oyesiku NM, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Preoperative Imaging Assessment of Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E524-6. PMID: 27635958.
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    61. Fleseriu M, Bodach ME, Tumialan LM, Bonert V, Oyesiku NM, Patil CG, Litvack Z, Aghi MK, Zada G. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pretreatment Endocrine Evaluation of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E527-9. PMID: 27635959.
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    62. Newman SA, Turbin RE, Bodach ME, Tumialan LM, Oyesiku NM, Litvack Z, Zada G, Patil CG, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Pretreatment Ophthalmology Evaluation in Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E530-2. PMID: 27635960.
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    63. Kuo JS, Barkhoudarian G, Farrell CJ, Bodach ME, Tumialan LM, Oyesiku NM, Litvack Z, Zada G, Patil CG, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Surgical Techniques and Technologies for the Management of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E536-8. PMID: 27635962.
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    64. Ziu M, Dunn IF, Hess C, Fleseriu M, Bodach ME, Tumialan LM, Oyesiku NM, Patel KS, Wang R, Carter BS, Chen JY, Chen CC, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Posttreatment Follow-up Evaluation of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 Oct; 79(4):E541-3. PMID: 27635964.
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    65. Aghi MK, Chen CC, Fleseriu M, Newman SA, Lucas JW, Kuo JS, Barkhoudarian G, Farrell CJ, Sheehan J, Ziu M, Dunn IF. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Management of Patients With Nonfunctioning Pituitary Adenomas: Executive Summary. Neurosurgery. 2016 Oct; 79(4):521-3. PMID: 27635956.
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    66. Zygourakis CC, Imber BS, Chen R, Han SJ, Blevins L, Molinaro A, Kahn JG, Aghi MK. Cost-Effectiveness Analysis of Surgical versus Medical Treatment of Prolactinomas. J Neurol Surg B Skull Base. 2017 Apr; 78(2):125-131. PMID: 28321375.
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    67. Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS, Butowski NA, Barani I, Phillips JJ, Perry A, Okada H. Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma. J Neurooncol. 2016 12; 130(3):543-552. PMID: 27624915.
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    68. Barajas RF, Butowski NA, Phillips JJ, Aghi MK, Berger MS, Chang SM, Cha S. The Development of Reduced Diffusion Following Bevacizumab Therapy Identifies Regions of Recurrent Disease in Patients with High-grade Glioma. Acad Radiol. 2016 09; 23(9):1073-82. PMID: 27443507.
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    69. Raleigh DR, Seymour ZA, Tomlin B, Theodosopoulos PV, Berger MS, Aghi MK, Geneser SE, Krishnamurthy D, Fogh SE, Sneed PK, McDermott MW. Resection and brain brachytherapy with permanent iodine-125 sources for brain metastasis. J Neurosurg. 2017 Jun; 126(6):1749-1755. PMID: 27367240.
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    70. Rolston JD, Han SJ, Aghi MK. Nationwide shift from microscopic to endoscopic transsphenoidal pituitary surgery. Pituitary. 2016 Jun; 19(3):248-50. PMID: 26441387.
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    71. Han SJ, Bankiewicz K, Butowski NA, Larson PS, Aghi MK. Interventional MRI-guided catheter placement and real time drug delivery to the central nervous system. Expert Rev Neurother. 2016 06; 16(6):635-9. PMID: 27054877.
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    72. Shah JK, Potts MB, Sneed PK, Aghi MK, McDermott MW. Surgical Cavity Constriction and Local Progression Between Resection and Adjuvant Radiosurgery for Brain Metastases. Cureus. 2016 Apr 19; 8(4):e575. PMID: 27226936.
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    73. Jahangiri A, Chin AT, Flanigan PM, Chen R, Bankiewicz K, Aghi MK. Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies. J Neurosurg. 2017 Jan; 126(1):191-200. PMID: 27035164.
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    74. Han SJ, Rolston JD, Zygourakis CC, Sun MZ, McDermott MW, Lau CY, Aghi MK. Preventing Delays in First-Case Starts on the Neurosurgery Service: A Resident-Led Initiative at an Academic Institution. J Surg Educ. 2016 Mar-Apr; 73(2):291-5. PMID: 26774935.
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    75. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652.
      View in: PubMed
    76. Bhawe KM, Aghi MK. Microarray Analysis in Glioblastomas. Methods Mol Biol. 2016; 1375:195-206. PMID: 26113463.
      View in: PubMed
    77. Aghi MK, Nahed BV, Sloan AE, Ryken TC, Kalkanis SN, Olson JJ. The role of surgery in the management of patients with diffuse low grade glioma: A systematic review and evidence-based clinical practice guideline. J Neurooncol. 2015 Dec; 125(3):503-30. PMID: 26530265.
      View in: PubMed
    78. Imber BS, Lee HS, Kunwar S, Blevins LS, Aghi MK. Hypophysitis: a single-center case series. Pituitary. 2015 Oct; 18(5):630-41. PMID: 25534888.
      View in: PubMed
    79. Jahangiri A, Wagner JR, Han SW, Tran MT, Miller LM, Chen R, Tom MW, Ostling LR, Kunwar S, Blevins L, Aghi MK. Improved versus worsened endocrine function after transsphenoidal surgery for nonfunctional pituitary adenomas: rate, time course, and radiological analysis. J Neurosurg. 2016 Mar; 124(3):589-95. PMID: 26252454.
      View in: PubMed
    80. Flanigan PM, Aghi MK. Adaptation to antiangiogenic therapy in neurological tumors. Cell Mol Life Sci. 2015 Aug; 72(16):3069-82. PMID: 25943307.
      View in: PubMed
    81. Rutkowski MJ, Breshears JD, Kunwar S, Aghi MK, Blevins LS. Approach to the postoperative patient with Cushing's disease. Pituitary. 2015 Apr; 18(2):232-7. PMID: 25702104.
      View in: PubMed
    82. Vogelbaum MA, Aghi MK. Convection-enhanced delivery for the treatment of glioblastoma. Neuro Oncol. 2015 Mar; 17 Suppl 2:ii3-ii8. PMID: 25746090.
      View in: PubMed
    83. Jahangiri A, Wagner JR, Chin AT, Han SW, Tran MT, Miller LM, Tom MW, Chen R, Kunwar S, Blevins L, Aghi MK. Incidence of headache as a presenting complaint in over 1000 patients with sellar lesions and factors predicting postoperative improvement. Clin Neurol Neurosurg. 2015 May; 132:16-20. PMID: 25746316.
      View in: PubMed
    84. Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M, Nguyen V, Wheeler ML, Murphy MP, Sanders TA, Jeffrey SS, Yeghiazarians Y, Rinaudo PF, Costello JF, Aghi MK, Maltepe E. HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. Cell Rep. 2015 Feb 17; 10(6):891-899. PMID: 25683712.
      View in: PubMed
    85. Osorio JA, Clark AJ, Safaee M, Tate MC, Aghi MK, Parsa A, McDermott MW. Intraoperative Conversion from Endoscopic to Open Transcortical-Transventricular Removal of Colloid Cysts as a Salvage Procedure. Cureus. 2015 Feb; 7(2):e247. PMID: 26180671.
      View in: PubMed
    86. Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. Factors predicting recurrence after resection of clival chordoma using variable surgical approaches and radiation modalities. Neurosurgery. 2015 Feb; 76(2):179-85; discussion 185-6. PMID: 25594191.
      View in: PubMed
    87. Rutkowski MJ, Flanigan PM, Aghi MK. Update on the management of recurrent Cushing's disease. Neurosurg Focus. 2015 Feb; 38(2):E16. PMID: 25639318.
      View in: PubMed
    88. Lau D, Rutledge C, Aghi MK. Cushing's disease: current medical therapies and molecular insights guiding future therapies. Neurosurg Focus. 2015 Feb; 38(2):E11. PMID: 25639313.
      View in: PubMed
    89. Zygourakis CC, Rolston JD, Lee HS, Partow C, Kunwar S, Aghi MK. Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco. Pituitary. 2015 Feb; 18(1):150-8. PMID: 24823438.
      View in: PubMed
    90. Awad AJ, Mohyeldin A, El-Sayed IH, Aghi MK. Sinonasal morbidity following endoscopic endonasal skull base surgery. Clin Neurol Neurosurg. 2015 Mar; 130:162-7. PMID: 25621713.
      View in: PubMed
    91. Cheng JS, Salinas R, Molinaro A, Chang EF, Kunwar S, Blevins L, Aghi MK. A predictive algorithm for evaluating elevated serum prolactin in patients with a sellar mass. J Clin Neurosci. 2015 Jan; 22(1):155-60. PMID: 25481269.
      View in: PubMed
    92. Lau D, Magill ST, Aghi MK. Molecularly targeted therapies for recurrent glioblastoma: current and future targets. Neurosurg Focus. 2014 Dec; 37(6):E15. PMID: 25434384.
      View in: PubMed
    93. Castro BA, Aghi MK. Bevacizumab for glioblastoma: current indications, surgical implications, and future directions. Neurosurg Focus. 2014 Dec; 37(6):E9. PMID: 25581938.
      View in: PubMed
    94. Ivan ME, Iorgulescu JB, El-Sayed I, McDermott MW, Parsa AT, Pletcher SD, Jahangiri A, Wagner J, Aghi MK. Risk factors for postoperative cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery. J Clin Neurosci. 2015 Jan; 22(1):48-54. PMID: 25439754.
      View in: PubMed
    95. Ivan ME, Safaee M, Oh T, Clark AJ, Sun MZ, Kim J, Bloch O, Jahangiri A, Phillips JJ, Aghi MK, Parsa AT. Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas. J Neurooncol. 2015 Jan; 121(1):53-61. PMID: 25200831.
      View in: PubMed
    96. Jahangiri A, Wagner J, Han SW, Tran MT, Miller LM, Tom MW, Ostling LR, Kunwar S, Blevins L, Aghi MK. Rate and time course of improvement in endocrine function after more than 1000 pituitary operations. Neurosurgery. 2014 Aug; 61 Suppl 1:163-6. PMID: 25032545.
      View in: PubMed
    97. Rolston JD, Han SJ, Cotter JA, El-Sayed IH, Aghi MK. Gangliogliomas of the optic pathway. J Clin Neurosci. 2014 Dec; 21(12):2244-9. PMID: 25043166.
      View in: PubMed
    98. Burnett R, Ibañez CE, Pettersson PL, Chen CI, Parab S, Huang T, Robbins J, Bankiewicz K, Aghi M, Logg C, Kasahara N, Pertschuk D, Gruber HE, Jolly DJ. Maintaining therapeutic activity in the operating room: compatibility of a gamma-retroviral replicating vector with clinical materials and biofluids. Mol Ther Methods Clin Dev. 2014; 1:14024. PMID: 26015967.
      View in: PubMed
    99. Lau D, Barker FG, Aghi MK. Awards, lectures, and fellowships sponsored by the AANS/CNS Section on Tumors. J Neurooncol. 2014 Sep; 119(3):583-91. PMID: 24893731.
      View in: PubMed
    100. Gruss CL, Al Komser M, Aghi MK, Pletcher SD, Goldberg AN, McDermott M, El-Sayed IH. Risk factors for cerebrospinal leak after endoscopic skull base reconstruction with nasoseptal flap. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):516-21. PMID: 24898075.
      View in: PubMed
    101. Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chordomas from the Surveillance, Epidemiology, and End Results (SEER) database. J Clin Neurosci. 2014 Sep; 21(9):1490-6. PMID: 24852903.
      View in: PubMed
    102. Jahangiri A, Wagner J, Han SW, Zygourakis CC, Han SJ, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins LS, Aghi MK. Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations. J Neurosurg. 2014 Jul; 121(1):67-74. PMID: 24834943.
      View in: PubMed
    103. Jones PS, Aghi MK, Muzikansky A, Shih HA, Barker FG, Curry WT. Outcomes and patterns of care in adult skull base chondrosarcomas from the SEER database. J Clin Neurosci. 2014 Sep; 21(9):1497-502. PMID: 24792724.
      View in: PubMed
    104. Burke K, Benet A, Aghi MK, El-Sayed I. Impact of platybasia and anatomic variance on surgical approaches to the craniovertebral junction. Laryngoscope. 2014 Aug; 124(8):1760-6. PMID: 24510671.
      View in: PubMed
    105. Ivan ME, Han SJ, Aghi MK. Tumors of the anterior skull base. Expert Rev Neurother. 2014 Apr; 14(4):425-38. PMID: 24564556.
      View in: PubMed
    106. Safaee M, Sun MZ, Oh T, Aghi MK, Berger MS, McDermott MW, Parsa AT, Bloch O. Use of thrombin-based hemostatic matrix during meningioma resection: a potential risk factor for perioperative thromboembolic events. Clin Neurol Neurosurg. 2014 Apr; 119:116-20. PMID: 24635939.
      View in: PubMed
    107. Potts MB, Shah JK, Molinaro AM, Blevins LS, Tyrrell JB, Kunwar S, Dowd CF, Hetts SW, Aghi MK. Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease. J Neurooncol. 2014 Feb; 116(3):593-600. PMID: 24398617.
      View in: PubMed
    108. Castro BA, Aghi MK. Getting more out of radiation therapy in glioblastoma. Neuro Oncol. 2014 Jan; 16(1):4-6. PMID: 24366974.
      View in: PubMed
    109. Osorio JA, Aghi MK. Optimizing glioblastoma resection: intraoperative mapping and beyond. CNS Oncol. 2014; 3(5):359-66. PMID: 25363008.
      View in: PubMed
    110. Bloch O, Crane CA, Fuks Y, Kaur R, Aghi MK, Berger MS, Butowski NA, Chang SM, Clarke JL, McDermott MW, Prados MD, Sloan AE, Bruce JN, Parsa AT. Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial. Neuro Oncol. 2014 Jan; 16(2):274-9. PMID: 24335700.
      View in: PubMed
    111. Jahangiri A, Aghi MK, Carbonell WS. ß1 integrin: Critical path to antiangiogenic therapy resistance and beyond. Cancer Res. 2014 Jan 01; 74(1):3-7. PMID: 24327727.
      View in: PubMed
    112. Jahangiri A, Potts M, Kunwar S, Blevins L, El-Sayed IH, Aghi MK. Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts. J Clin Neurosci. 2014 May; 21(5):779-85. PMID: 24308953.
      View in: PubMed
    113. Awad AJ, Rowland NC, Mian M, Hiniker A, Tate M, Aghi MK. Etiology, prognosis, and management of secondary pituitary abscesses forming in underlying pituitary adenomas. J Neurooncol. 2014 May; 117(3):469-76. PMID: 24185442.
      View in: PubMed
    114. Ayodele MO, Pekmezci M, Aghi MK, Scott BJ. Headache and focal neurologic deficits in a 37-year-old woman. JAMA Neurol. 2013 Nov; 70(11):1445-9. PMID: 24081305.
      View in: PubMed
    115. Han SJ, Rolston JD, Jahangiri A, Aghi MK. Rathke's cleft cysts: review of natural history and surgical outcomes. J Neurooncol. 2014 Apr; 117(2):197-203. PMID: 24146189.
      View in: PubMed
    116. Jahangiri A, Wagner J, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins L, Aghi MK. Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations. J Neurosurg. 2013 Dec; 119(6):1478-83. PMID: 23971964.
      View in: PubMed
    117. Jahangiri A, Clark AJ, Han SJ, Kunwar S, Blevins LS, Aghi MK. Socioeconomic factors associated with pituitary apoplexy. J Neurosurg. 2013 Dec; 119(6):1432-6. PMID: 23889139.
      View in: PubMed
    118. Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8. PMID: 23685641.
      View in: PubMed
    119. Bloch O, Safaee M, Sun MZ, Butowski NA, McDermott MW, Berger MS, Aghi MK, Parsa AT. Disseminated progression of glioblastoma after treatment with bevacizumab. Clin Neurol Neurosurg. 2013 Sep; 115(9):1795-801. PMID: 23706614.
      View in: PubMed
    120. Carbonell WS, DeLay M, Jahangiri A, Park CC, Aghi MK. ß1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013 May 15; 73(10):3145-54. PMID: 23644530.
      View in: PubMed
    121. Hiniker A, Hagenkord JM, Powers MP, Aghi MK, Prados MD, Perry A. Gliosarcoma arising from an oligodendroglioma (oligosarcoma). Clin Neuropathol. 2013 May-Jun; 32(3):165-70. PMID: 23254140.
      View in: PubMed
    122. Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLoS One. 2013; 8(4):e62758. PMID: 23646141.
      View in: PubMed
    123. Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK. Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis. Neurosurg Rev. 2013 Jul; 36(3):349-59. PMID: 23568697.
      View in: PubMed
    124. Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT. Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neurooncol. 2013 May; 113(1):117-25. PMID: 23468001.
      View in: PubMed
    125. Jahangiri A, De Lay M, Miller LM, Carbonell WS, Hu YL, Lu K, Tom MW, Paquette J, Tokuyasu TA, Tsao S, Marshall R, Perry A, Bjorgan KM, Chaumeil MM, Ronen SM, Bergers G, Aghi MK. Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin Cancer Res. 2013 Apr 01; 19(7):1773-83. PMID: 23307858.
      View in: PubMed
    126. Kaur G, Kane AJ, Sughrue ME, Madden M, Oh MC, Sun MZ, Safaee M, El-Sayed I, Aghi M, McDermott MW, Berger MS, Parsa AT. The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma. J Clin Neurosci. 2013 Feb; 20(2):281-6. PMID: 23266076.
      View in: PubMed
    127. Xi Y, Wei Y, Sennino B, Ulsamer A, Kwan I, Brumwell AN, Tan K, Aghi MK, McDonald DM, Jablons DM, Chapman HA. Identification of pY654-ß-catenin as a critical co-factor in hypoxia-inducible factor-1a signaling and tumor responses to hypoxia. Oncogene. 2013 Oct 17; 32(42):5048-57. PMID: 23246962.
      View in: PubMed
    128. Jahangiri A, Jian B, Miller L, El-Sayed IH, Aghi MK. Skull base chordomas: clinical features, prognostic factors, and therapeutics. Neurosurg Clin N Am. 2013 Jan; 24(1):79-88. PMID: 23174359.
      View in: PubMed
    129. Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS, Parsa AT. Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article. J Neurosurg. 2012 Dec; 117(6):1032-8. PMID: 23039151.
      View in: PubMed
    130. Ivan ME, Jahangiri A, El-Sayed IH, Aghi MK. Minimally invasive approaches to the anterior skull base. Neurosurg Clin N Am. 2013 Jan; 24(1):19-37. PMID: 23174355.
      View in: PubMed
    131. Hu YL, Jahangiri A, Delay M, Aghi MK. Tumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapy. Cancer Res. 2012 Sep 01; 72(17):4294-9. PMID: 22915758.
      View in: PubMed
    132. Oh MC, Tihan T, Kunwar S, Blevins L, Aghi MK. Clinical management of pituitary carcinomas. Neurosurg Clin N Am. 2012 Oct; 23(4):595-606. PMID: 23040746.
      View in: PubMed
    133. Oh MC, Kunwar S, Blevins L, Aghi MK. Medical versus surgical management of prolactinomas. Neurosurg Clin N Am. 2012 Oct; 23(4):669-78. PMID: 23040751.
      View in: PubMed
    134. Aghi MK, Blevins LS. Neurosurgery Clinics of North America. Management of pituitary tumors. Preface. Neurosurg Clin N Am. 2012 Oct; 23(4):ix. PMID: 23040753.
      View in: PubMed
    135. Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 2012 Jul 10; 22(1):21-35. PMID: 22789536.
      View in: PubMed
    136. Barajas RF, Phillips JJ, Parvataneni R, Molinaro A, Essock-Burns E, Bourne G, Parsa AT, Aghi MK, McDermott MW, Berger MS, Cha S, Chang SM, Nelson SJ. Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging. Neuro Oncol. 2012 Jul; 14(7):942-54. PMID: 22711606.
      View in: PubMed
    137. Hu YL, Jahangiri A, De Lay M, Aghi MK. Hypoxia-induced tumor cell autophagy mediates resistance to anti-angiogenic therapy. Autophagy. 2012 Jun; 8(6):979-81. PMID: 22714142.
      View in: PubMed
    138. DeLay M, Jahangiri A, Carbonell WS, Hu YL, Tsao S, Tom MW, Paquette J, Tokuyasu TA, Aghi MK. Microarray analysis verifies two distinct phenotypes of glioblastomas resistant to antiangiogenic therapy. Clin Cancer Res. 2012 May 15; 18(10):2930-42. PMID: 22472177.
      View in: PubMed
    139. Hu YL, DeLay M, Jahangiri A, Molinaro AM, Rose SD, Carbonell WS, Aghi MK. Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res. 2012 Apr 01; 72(7):1773-83. PMID: 22447568.
      View in: PubMed
    140. Jahangiri A, Aghi MK. Pseudoprogression and treatment effect. Neurosurg Clin N Am. 2012 Apr; 23(2):277-87, viii-ix. PMID: 22440871.
      View in: PubMed
    141. Clark AJ, Lamborn KR, Butowski NA, Chang SM, Prados MD, Clarke JL, McDermott MW, Parsa AT, Berger MS, Aghi MK. Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment. Neurosurgery. 2012 Feb; 70(2):361-70. PMID: 21841523.
      View in: PubMed
    142. Vogelbaum MA, Jost S, Aghi MK, Heimberger AB, Sampson JH, Wen PY, Macdonald DR, Van den Bent MJ, Chang SM. Application of novel response/progression measures for surgically delivered therapies for gliomas: Response Assessment in Neuro-Oncology (RANO) Working Group. Neurosurgery. 2012 Jan; 70(1):234-43; discussion 243-4. PMID: 21593697.
      View in: PubMed
    143. Agarwalla PK, Aghi MK. Oncolytic herpes simplex virus engineering and preparation. Methods Mol Biol. 2012; 797:1-19. PMID: 21948465.
      View in: PubMed
    144. Barajas RF, Perry A, Sughrue M, Aghi M, Cha S. Intracranial subdural osteoma: a rare benign tumor that can be differentiated from other calcified intracranial lesions utilizing MR imaging. J Neuroradiol. 2012 Oct; 39(4):263-6. PMID: 22197691.
      View in: PubMed
    145. Potts MB, Jahangiri A, Lamborn KR, Blevins LS, Kunwar S, Aghi MK. Suprasellar Rathke cleft cysts: clinical presentation and treatment outcomes. Neurosurgery. 2011 Nov; 69(5):1058-68; discussion 1068-7. PMID: 21673610.
      View in: PubMed
    146. Jahangiri A, Aghi MK. Biomarkers predicting tumor response and evasion to anti-angiogenic therapy. Biochim Biophys Acta. 2012 Jan; 1825(1):86-100. PMID: 22067555.
      View in: PubMed
    147. Sughrue ME, Chang EF, Gabriel RA, Aghi MK, Blevins LS. Excess mortality for patients with residual disease following resection of pituitary adenomas. Pituitary. 2011 Sep; 14(3):276-83. PMID: 21476061.
      View in: PubMed
    148. Kaur G, Bloch O, Jian BJ, Kaur R, Sughrue ME, Aghi MK, McDermott MW, Berger MS, Chang SM, Parsa AT. A critical evaluation of cystic features in primary glioblastoma as a prognostic factor for survival. J Neurosurg. 2011 Oct; 115(4):754-9. PMID: 21761969.
      View in: PubMed
    149. Aghi MK, Walcott BP, Nahed BV, Cvetanovich GL, Kahle KT, Redjal N, Coumans JV. Determinants of initial bone graft volume loss in posterolateral lumbar fusion. J Clin Neurosci. 2011 Sep; 18(9):1193-6. PMID: 21745744.
      View in: PubMed
    150. Jahangiri A, Lamborn KR, Blevins L, Kunwar S, Aghi MK. Factors associated with delay to pituitary adenoma diagnosis in patients with visual loss. J Neurosurg. 2012 Feb; 116(2):283-9. PMID: 21740118.
      View in: PubMed
    151. Jahangiri A, Molinaro AM, Tarapore PE, Blevins L, Auguste KI, Gupta N, Kunwar S, Aghi MK. Rathke cleft cysts in pediatric patients: presentation, surgical management, and postoperative outcomes. Neurosurg Focus. 2011 Jul; 31(1):E3. PMID: 21721868.
      View in: PubMed
    152. Oh MC, Aghi MK. Dopamine agonist-resistant prolactinomas. J Neurosurg. 2011 May; 114(5):1369-79. PMID: 21214334.
      View in: PubMed
    153. Clark AJ, Butowski NA, Chang SM, Prados MD, Clarke J, Polley MY, Sughrue ME, McDermott MW, Parsa AT, Berger MS, Aghi MK. Impact of bevacizumab chemotherapy on craniotomy wound healing. J Neurosurg. 2011 Jun; 114(6):1609-16. PMID: 21142749.
      View in: PubMed
    154. Rowland NC, Aghi MK. Radiation treatment strategies for acromegaly. Neurosurg Focus. 2010 Oct; 29(4):E12. PMID: 20887122.
      View in: PubMed
    155. Zlotnick D, Kalkanis SN, Quinones-Hinojosa A, Chung K, Linskey ME, Jensen RL, DeMonte F, Barker FG, Racine CA, Berger MS, Black PM, Cusimano M, Sekhar LN, Parsa A, Aghi M, McDermott MW. FACT-MNG: tumor site specific web-based outcome instrument for meningioma patients. J Neurooncol. 2010 Sep; 99(3):423-31. PMID: 20853019.
      View in: PubMed
    156. Tate MC, Jahangiri A, Blevins L, Kunwar S, Aghi MK. Infected Rathke cleft cysts: distinguishing factors and factors predicting recurrence. Neurosurgery. 2010 Sep; 67(3):762-9; discussion 769. PMID: 20651624.
      View in: PubMed
    157. Sughrue ME, Aghi MK. Reconstruction of dural defects of the endonasal skull base. Neurosurg Clin N Am. 2010 Oct; 21(4):637-41, vi. PMID: 20947032.
      View in: PubMed
    158. Nahed BV, Walcott BP, Ortman AJ, Kahle KT, Aghi M, Peterfreund RA, Coumans JV. Interval, acute onset airway obstruction associated with a fracture of the C4 vertebra in a patient with ankylosing spondylitis. J Clin Neurosci. 2010 Aug; 17(8):1085-8. PMID: 20580996.
      View in: PubMed
    159. Chahal M, Xu Y, Lesniak D, Graham K, Famulski K, Christensen JG, Aghi M, Jacques A, Murray D, Sabri S, Abdulkarim B. MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro Oncol. 2010 Aug; 12(8):822-33. PMID: 20179017.
      View in: PubMed
    160. Rose SD, Aghi MK. Mechanisms of evasion to antiangiogenic therapy in glioblastoma. Clin Neurosurg. 2010; 57:123-8. PMID: 21280504.
      View in: PubMed
    161. Yang I, Aghi MK. New advances that enable identification of glioblastoma recurrence. Nat Rev Clin Oncol. 2009 Nov; 6(11):648-57. PMID: 19806145.
      View in: PubMed
    162. Gabeau-Lacet D, Aghi M, Betensky RA, Barker FG, Loeffler JS, Louis DN. Bone involvement predicts poor outcome in atypical meningioma. J Neurosurg. 2009 Sep; 111(3):464-71. PMID: 19267533.
      View in: PubMed
    163. Aghi M, Blevins LS. Recent advances in the treatment of acromegaly. Curr Opin Endocrinol Diabetes Obes. 2009 Aug; 16(4):304-7. PMID: 19491667.
      View in: PubMed
    164. Tate MC, Aghi MK. Biology of angiogenesis and invasion in glioma. Neurotherapeutics. 2009 Jul; 6(3):447-57. PMID: 19560735.
      View in: PubMed
    165. Aghi MK, Batchelor TT, Louis DN, Barker FG, Curry WT. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. J Neurooncol. 2009 May; 93(1):115-20. PMID: 19430887.
      View in: PubMed
    166. Chang SM, Nelson S, Vandenberg S, Cha S, Prados M, Butowski N, McDermott M, Parsa AT, Aghi M, Clarke J, Berger M. Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma. J Neurooncol. 2009 May; 92(3):401-15. PMID: 19357966.
      View in: PubMed
    167. Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 2009 Apr 15; 69(8):3472-81. PMID: 19351838.
      View in: PubMed
    168. Aghi MK, Carter BS, Cosgrove GR, Ojemann RG, Amin-Hanjani S, Martuza RL, Curry WT, Barker FG. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery. 2009 Jan; 64(1):56-60; discussion 60. PMID: 19145156.
      View in: PubMed
    169. Aghi MK, Chiocca EA. Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication. Mol Ther. 2009 Jan; 17(1):8-9. PMID: 19116635.
      View in: PubMed
    170. Aghi MK, Liu TC, Rabkin S, Martuza RL. Hypoxia enhances the replication of oncolytic herpes simplex virus. Mol Ther. 2009 Jan; 17(1):51-6. PMID: 18957963.
      View in: PubMed
    171. Aghi MK. Management of recurrent and refractory Cushing disease. Nat Clin Pract Endocrinol Metab. 2008 Oct; 4(10):560-8. PMID: 18711406.
      View in: PubMed
    172. Aghi M, Visted T, Depinho RA, Chiocca EA. Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16. Oncogene. 2008 Jul 10; 27(30):4249-54. PMID: 18345032.
      View in: PubMed
    173. Aghi MK, Petit J, Chapman P, Loeffler J, Klibanski A, Biller BM, Swearingen B. Management of recurrent and refractory Cushing's disease with reoperation and/or proton beam radiosurgery. Clin Neurosurg. 2008; 55:141-4. PMID: 19248680.
      View in: PubMed
    174. Aghi MK, Eskandar EN, Carter BS, Curry WT, Barker FG. Increased prevalence of obesity and obesity-related postoperative complications in male patients with meningiomas. Neurosurgery. 2007 Oct; 61(4):754-60; discussion 760-1. PMID: 17986936.
      View in: PubMed
    175. Aghi M, Rabkin SD, Martuza RL. Angiogenic response caused by oncolytic herpes simplex virus-induced reduced thrombospondin expression can be prevented by specific viral mutations or by administering a thrombospondin-derived peptide. Cancer Res. 2007 Jan 15; 67(2):440-4. PMID: 17234749.
      View in: PubMed
    176. Aghi MK, Eskandar EN, Carter BS, Curry WT, Barker FG. Increased prevalence of obesity and obesity-related postoperative complications in male meningioma patients. Clin Neurosurg. 2007; 54:236-40. PMID: 18504925.
      View in: PubMed
    177. Aghi M, Cohen KS, Klein RJ, Scadden DT, Chiocca EA. Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes. Cancer Res. 2006 Sep 15; 66(18):9054-64. PMID: 16982747.
      View in: PubMed
    178. Aghi M, Chiocca EA. Gene therapy for glioblastoma. Neurosurg Focus. 2006 Apr 15; 20(4):E18. PMID: 16709023.
      View in: PubMed
    179. Aghi M, Kluwe L, Webster MT, Jacoby LB, Barker FG, Ojemann RG, Mautner VF, MacCollin M. Unilateral vestibular schwannoma with other neurofibromatosis type 2-related tumors: clinical and molecular study of a unique phenotype. J Neurosurg. 2006 Feb; 104(2):201-7. PMID: 16509493.
      View in: PubMed
    180. Aghi M, Rabkin S, Martuza RL. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. J Natl Cancer Inst. 2006 Jan 04; 98(1):38-50. PMID: 16391370.
      View in: PubMed
    181. Aghi M, Barker Ii FG. Benign adult brain tumors: an evidence-based medicine review. Prog Neurol Surg. 2006; 19:80-96. PMID: 17033148.
      View in: PubMed
    182. Aghi M, Rabkin S, Martuza RL. Oncolytic herpes simplex virus mutants exhibit enhanced replication in glioma cells evading temozolomide chemotherapy through deoxyribonucleic acid repair. Clin Neurosurg. 2006; 53:65-76. PMID: 17380741.
      View in: PubMed
    183. Aghi M, Gaviani P, Henson JW, Batchelor TT, Louis DN, Barker FG. Magnetic resonance imaging characteristics predict epidermal growth factor receptor amplification status in glioblastoma. Clin Cancer Res. 2005 Dec 15; 11(24 Pt 1):8600-5. PMID: 16361543.
      View in: PubMed
    184. Aghi M, Martuza RL. Oncolytic viral therapies - the clinical experience. Oncogene. 2005 Nov 21; 24(52):7802-16. PMID: 16299539.
      View in: PubMed
    185. Aghi M, Kiehl TR, Brisman JL. Breast adenocarcinoma metastatic to epidural cervical spine meningioma: case report and review of the literature. J Neurooncol. 2005 Nov; 75(2):149-55. PMID: 16132512.
      View in: PubMed
    186. Aghi M, Rabkin S. Viral vectors as therapeutic agents for glioblastoma. Curr Opin Mol Ther. 2005 Oct; 7(5):419-30. PMID: 16248277.
      View in: PubMed
    187. Aghi M, Chiocca EA. Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors. Mol Ther. 2005 Dec; 12(6):994-1005. PMID: 16137927.
      View in: PubMed
    188. Hoh BL, Aghi M, Pryor JC, Ogilvy CS. Heparin-induced thrombocytopenia Type II in subarachnoid hemorrhage patients: incidence and complications. Neurosurgery. 2005 Aug; 57(2):243-8; discussion 243-8. PMID: 16094152.
      View in: PubMed
    189. Aghi M, Coumans JV, Valery-Coumans J, Brisman JL. Subarachnoid hematoma, hydrocephalus, and aseptic meningitis resulting from a high cervical myelogram. J Spinal Disord Tech. 2004 Aug; 17(4):348-51. PMID: 15280770.
      View in: PubMed
    190. Chiocca EA, Aghi M, Fulci G. Viral therapy for glioblastoma. Cancer J. 2003 May-Jun; 9(3):167-79. PMID: 12952302.
      View in: PubMed
    191. Aghi M, Chiocca EA. Genetically engineered herpes simplex viral vectors in the treatment of brain tumors: a review. Cancer Invest. 2003 Apr; 21(2):278-92. PMID: 12743992.
      View in: PubMed
    192. Aghi M, Hochberg F, Breakefield XO. Prodrug activation enzymes in cancer gene therapy. J Gene Med. 2000 May-Jun; 2(3):148-64. PMID: 10894261.
      View in: PubMed
    193. Aghi M, Chou TC, Suling K, Breakefield XO, Chiocca EA. Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res. 1999 Aug 15; 59(16):3861-5. PMID: 10463570.
      View in: PubMed
    194. Aghi M, Kramm CM, Breakefield XO. Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst. 1999 Jul 21; 91(14):1233-41. PMID: 10413425.
      View in: PubMed
    195. Pechan PA, Herrlinger U, Aghi M, Jacobs A, Breakefield XO. Combined HSV-1 recombinant and amplicon piggyback vectors: replication-competent and defective forms, and therapeutic efficacy for experimental gliomas. J Gene Med. 1999 May-Jun; 1(3):176-85. PMID: 10738566.
      View in: PubMed
    196. Aghi M, Kramm CM, Chou TC, Breakefield XO, Chiocca EA. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst. 1998 Mar 04; 90(5):370-80. PMID: 9498487.
      View in: PubMed
    197. Kramm CM, Chase M, Herrlinger U, Jacobs A, Pechan PA, Rainov NG, Sena-Esteves M, Aghi M, Barnett FH, Chiocca EA, Breakefield XO. Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy. Hum Gene Ther. 1997 Nov 20; 8(17):2057-68. PMID: 9414254.
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