Ruby Ghadially, MD

InstitutionUniversity of California San Francisco
AddressVA 203, 4150 Clement St.
San Francisco CA 94121
Phone415-221-4810 ext. 3373
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    Collapse Research 
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    Characterization of Human Epidermal Stem Cells
    VA I01BX000794Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator
    Reversing Epidermal Stem Cell Aging: Role of Bmi-1 and the Stem Cell Niche
    NIH/NIAMS R21AR060651Sep 10, 2010 - May 31, 2013
    Role: Principal Investigator
    Characterization of Epidermal Stem Cells
    NIH/NIAMS R01AR053765Sep 1, 2005 - May 31, 2011
    Role: Principal Investigator
    Epidermal Stem Cells: Age-Related Changes
    NIH/NIAMS R03AR048667Sep 15, 2002 - Aug 31, 2005
    Role: Principal Investigator
    Age-Related Changes in Epidermal Stem Cells
    NIH/NIA R03AG020372Sep 30, 2001 - Aug 31, 2003
    Role: Principal Investigator
    NIH/NIAMS K08AR001973Jul 20, 1996 - May 31, 2002
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu SS, Gray JW, Purdom E, Paus R, Vaske CJ, Benz SC, Song JS, Cho RJ. Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution. Cell Rep. 2018 Oct 23; 25(4):871-883. PMID: 30355494.
      View in: PubMed
    2. Charruyer A, Ghadially R. Influence of pH on Skin Stem Cells and Their Differentiation. Curr Probl Dermatol. 2018; 54:71-78. PMID: 30130775.
      View in: PubMed
    3. Charruyer A, Fong S, Vitcov GG, Sklar S, Tabernik L, Taneja M, Caputo M, Soeung C, Yue L, Uchida Y, Arron ST, Horton KM, Foster RD, Sano S, North JP, Ghadially R. Brief Report: Interleukin-17A-Dependent Asymmetric Stem Cell Divisions Are Increased in Human Psoriasis: A Mechanism Underlying Benign Hyperproliferation. Stem Cells. 2017 08; 35(8):2001-2007. PMID: 28600817.
      View in: PubMed
    4. Charruyer A, Fong S, Yue L, Arron ST, Ghadially R. Phycosaccharide AI, a mixture of alginate polysaccharides, increases stem cell proliferation in aged keratinocytes. Exp Dermatol. 2016 09; 25(9):738-40. PMID: 27095184.
      View in: PubMed
    5. Yue L, Huang ZM, Fong S, Leong S, Jakowatz JG, Charruyer-Reinwald A, Wei M, Ghadially R. Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma. Melanoma Res. 2015 Apr; 25(2):138-48. PMID: 25643237.
      View in: PubMed
    6. Szabo AZ, Fong S, Yue L, Zhang K, Strachan LR, Scalapino K, Mancianti ML, Ghadially R. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells. 2013 Apr; 31(4):786-99. PMID: 23335266; PMCID: PMC4104573.
    7. Charruyer A, Strachan LR, Yue L, Toth AS, Cecchini G, Mancianti ML, Ghadially R. CD133 is a marker for long-term repopulating murine epidermal stem cells. J Invest Dermatol. 2012 Nov; 132(11):2522-33. PMID: 22763787; PMCID: PMC3997791.
    8. Ghadially R. 25 years of epidermal stem cell research. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):797-810. PMID: 22205306; PMCID: PMC3998762.
    9. Ghadially R. The role of stem and circulating cells in cancer metastasis. J Surg Oncol. 2011 May 01; 103(6):555-7. PMID: 21480249.
      View in: PubMed
    10. Boonyaratanakornkit JB, Yue L, Strachan LR, Scalapino KJ, LeBoit PE, Lu Y, Leong SP, Smith JE, Ghadially R. Selection of tumorigenic melanoma cells using ALDH. J Invest Dermatol. 2010 Dec; 130(12):2799-808. PMID: 20739950.
      View in: PubMed
    11. Strachan LR, Ghadially R. Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay. Methods Mol Biol. 2010; 585:421-32. PMID: 19908020; PMCID: PMC2783164.
    12. Charruyer A, Barland CO, Yue L, Wessendorf HB, Lu Y, Lawrence HJ, Mancianti ML, Ghadially R. Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis. J Invest Dermatol. 2009 Nov; 129(11):2574-83. PMID: 19458632.
      View in: PubMed
    13. Strachan LR, Ghadially R. Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited. Stem Cell Rev. 2008 Sep; 4(3):149-57. PMID: 18574734.
      View in: PubMed
    14. Strachan LR, Scalapino KJ, Lawrence HJ, Ghadially R. Rapid adhesion to collagen isolates murine keratinocytes with limited long-term repopulating ability in vivo despite high clonogenicity in vitro. Stem Cells. 2008 Jan; 26(1):235-43. PMID: 17932419.
      View in: PubMed
    15. Silvander M, Ringstad L, Ghadially R, Sk├Âld T. A new water-based topical carrier with polar skin-lipids. Lipids Health Dis. 2006 May 03; 5:12. PMID: 16672068; PMCID: PMC1464131.
    16. Ghadially R. Epidermal stem cells. Adv Dermatol. 2005; 21:335-55. PMID: 16350449.
      View in: PubMed
    17. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004 Feb; 122(2):330-6. PMID: 15009713.
      View in: PubMed
    18. Elias PM, Ghadially R. The aged epidermal permeability barrier: basis for functional abnormalities. Clin Geriatr Med. 2002 Feb; 18(1):103-20, vii. PMID: 11913735.
      View in: PubMed
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