Thea Mauro, MD

Title(s)Professor, Dermatology
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #001
San Francisco CA 94143
Phone415-750-2091 ext. 3371
ORCID ORCID Icon0000-0003-3623-0070 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Bryn Mawr College, Bryn Mawr, PAAB06/1979English
    Drexel College of Medicine, Philadelphia, PAMD06/1983Medicine
    Hahnemann Med College, Philadelphia, PA06/1984Internal Medicine
    Univ of Pennsylvania, Philadelphia, PA06/1985Physiology Fellowship
    UC Davis, Davis, CA01/1988Dermatology Residency
    Univ of Pennsylvania, Pittsburgh, PA06/1989Dermatology Instructor
    UC Davis, Davis, CA06/1991Asst Prof, Dermatology
    UC Davis, Davis, CA06/1992Asst Prof in Res, Dermatology
    SFVA Medical Center, San Francisco, CA06/1997Asst Serv Chief, Dermatology
    UCSF, San Francisco, CA06/1997Asst Prof in Res, Dermatology
    SFVA Health Care System, San Francisco, CA06/1999Inter Serv Chief, Dermatology
    University of Padova, Padova, Italy06/2001Visiting Scientist
    SFVA Health Care System, San Francisco, CA2018Inter Dep Chief of Staff
    SFVA Health Care System, San Francisco, CA2019Serv Chief, Dermatology
    UCSF, San Francisco, CA2019Vice Chair, Assoc Prof, Dermatology
    SFVA Health Care System, San Francisco, CA2019Clin Dir, Plan & Develop
    SFVA Health Care System, San Francisco, CApresentDeputy Chief of Staff
    SFVA Health Care System, San Francisco, CApresentChief, Mission Bay Derm Lab
    UCSF, San Francisco, CApresentProfessor, Dermatology
    Collapse Awards and Honors
    Gordon Research Conferences2011  - 2013Chair, Barrier Function of Mammalian Skin
    School of Medicine, UCSF1987  - 1988Medical Scholar Award
    NIH2010  - 2021Ad Hoc Member, Various Study Sections

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Optimizing Keratinocyte Calcium Signaling Enhances Differentiation in Aged Epidermis
    Department of Veterans Affairs I01BX006094Oct 1, 2023 - Sep 30, 2027
    Role: Principal Investigator
    Description: To determine why CaSR expression is decreased in intrinsically and extrinsically aged keratinocytes, identifying age-dependent defects in transcriptional and epigenetic regulation; To test how increasing CaSR expression improves CaSR, downstream gene expression and age-related functional defects in differentiation; To test how activating CaSR function by treating with CaSR agonists improves downstream gene expression, Ca2+ signaling and age-related functional defects in differentiation, using in vitro models; To test which topical agents that enhance CaSR signaling are most effective in vivo in ameliorating aged-related defects in differentiation, barrier homeostasis and skin/systemic inflammation.
    Sodium in the Skin and Atopic Dermatitis: The SIS-AD Study
    NIH R01AR082831Sep 22, 2023 - Aug 31, 2028
    Role: Co-Investigator
    Description: For the 32 million people in the U.S. currently living with atopic dermatitis (eczema), the waxing and waning course of their chronic disease is impossible to predict, does not respond uniformly to treatment, and results in substantial economic impact and decreased quality of life. Understanding drivers of the disease activity is essential to developing treatments, and sodium/salt consumption is a likely contributor. Using a new MRI technique to image sodium in the skin on a cohort of 90 older adult men and women followed for two years, we will test novel hypotheses about the role of dietary salt intake and skin barrier function on sodium storage in the skin and atopic dermatitis severity and persistence.
    Precision Medicine Approaches to Chronic Inflammatory Skin Disease of Older Veterans
    Department of Veterans Affairs I01CX002608Jul 1, 2023 - Jun 30, 2027
    Role: Co-Investigator
    Description: This project will develop a precision medicine approach for choosing optimal targeted treatment for individual cases of elderly atopic dermatitis by 1) defining transcriptional signatures for elderly AD before and during IL-4Ra blocking treatment and 2) identifying a transcriptional signature which predicts IL-4Ra blockade response in elderly AD. We will then ascertain the functional impact of specific rmAD43 elderly atopic dermatitis genes on T cell inflammatory phenotypes.
    The genomic landscape and evolution of cutaneous squamous cell carcinoma
    NIH R01CA265786Sep 22, 2022 - Aug 31, 2027
    Role: Co-Investigator
    Description: Cutaneous squamous cell carcinoma is a form of skin cancer, originating from keratinocytes, that kills an estimated 8000 people per year in the United States. Compared to other cancers with similar incidences, death tolls, and/or economic burdens, our understanding of the genomic landscape and genetic evolution of cutaneous squamous cell carcinoma is limited. The overarching goals of this grant are to define the driver mutations in cutaneous squamous cell carcinomas, to delineate the genetic evolution of cutaneous squamous cell carcinomas from precursor lesions, and to establish the earliest genetic alterations occurring in pre- neoplastic keratinocytes. Towards these goals, in aim1, we will identify driver mutations in exome and genome sequencing data covering cutaneous squamous cell carcinoma. This data will be aggregated from publicly available sources as well as new sequencing data from our own institution, collectively comprising the largest analysis of cutaneous squamous cell carcinoma sequencing data to date. In aim2, we will sequence cutaneous squamous cell carcinomas and the remnant precursor lesions from which they arose. Most cutaneous squamous cell carcinomas are discovered adjacent to benign precursor lesions known as actinic keratoses, and here, we will analyze patient-matched lesions to reveal the mutations driving the transition from the benign to the malignant state. In aim3, we will elucidate the earliest somatic alterations occurring in individual keratinocytes from normal skin. Deep sequencing of normal skin has shown that keratinocytes can form patches of related cells, sometimes harboring mutations known to drive cutaneous squamous cell carcinoma, but no studies have truly genotyped keratinocytes at single-cell resolution, leaving gaps in our knowledge of the incipient events that occur in pre-neoplastic keratinocytes. We have developed an innovative workflow to call mutations in individual skin cells with high specificity and sensitivity, permitting us to catalog, for the first time, the genomic alterations in human skin at single-cell resolution. Similar lines of genomic studies have proven fundamental in advancing our understanding of other cancers by revealing therapeutic points of intervention, biomarkers to measure disease progression, biomarkers to estimate disease likelihood, and guidance on the best prevention tactics. Here, we will address these gaps in knowledge for cutaneous squamous cell carcinoma. Taken together, completion of these studies will realize longstanding goals within the field of dermatology, which will pave the way for new treatment strategies and new preventions strategies to alleviate the public health burden posed by cutaneous squamous cell carcinoma.
    Spatial and Temporal Activation in Aged vs. Young Skin
    Mt. Zion Health Fund/UCSF CA-0203557Aug 1, 2022 - Feb 1, 2024
    Role: Principal Investigator
    Description: This project identifies possible therapeutic targets that may normalize wound healing in aged skin.
    Epidermal Skin Barrier and Inflammaging
    BAKAR Aging Research Institute (UCSF) Nov 1, 2021 - Oct 31, 2022
    Role: Principal Investigator
    Description: This project investigates properties of the aging human epidermis and how it might be a significant source of inflammation in other parts of the body.
    Measuring Biomarkers in Skin in Response to Chemical Treatment
    Unilever R&D Feb 1, 2019 - Dec 31, 2019
    Role: Principal Investigator
    Description: This project aims to measure epidermal calcium gradient, proliferation and differentiation biomarkers in response to chemical treatment.
    Full Thickness Skin Models from Human Pluripotent Stem Cells for Identification and Testing Effectiveness of Personalized Therapies in Atopic Dermatitis
    Leo Foundation Aug 1, 2017 - Jun 30, 2021
    Role: Co-Principal Investigator
    Description: The overall goal of this study is to develop human skin equivalent models from fibroblast-derived stem cells obtained from skin biopsies from patients with atopic dermatitis.
    Generation and Characterization of Non-Human Animal Skin Models
    VitroLabs, Inc. May 1, 2017 - Sep 30, 2016
    Role: Principal Investigator
    Description: The overall goal of this study is to develop skin equivalents comprised of dermal and epidermal cells from stem cells differentiated into their dermal and epidermal components.
    Modeling Lip Barrier Properties
    Pfizer Corporation Oct 1, 2016 - Sep 30, 2018
    Role: Principal Investigator
    Description: The overall goal of this study is to test bioactive compounds of the lip equivalent cultures developed in a previous project for Pfizer.
    2013 Barrier Function of Mammalian Skin Gordon Research Conferences
    NIH R13AR064663Apr 1, 2013 - Mar 31, 2014
    Role: Principal Investigator
    The Lipid and Tight Junction Epidermal Barriers are Interdependent
    NIH R21AR061583Aug 1, 2012 - May 31, 2014
    Role: Principal Investigator
    Pathogenesis and Therapy of Ichthyosis in Disorders of Lipid Metabolism
    NIH R01AR061106Mar 1, 2012 - Feb 29, 2024
    Role: Principal Investigator
    Description: To determine why CaSR expression is decreased in intrinsically and extrinsically aged keratinocytes, identifying age-dependent defects in transcriptional and epigenetic regulation; To test how increasing CaSR expression improves CaSR, downstream gene expression and age-related functional defects in differentiation; To test how activating CaSR function by treating with CaSR agonists improves downstream gene expression, Ca2+ signaling and age-related functional defects in differentiation, using in vitro models; To test which topical agents that enhance CaSR signaling are most effective in vivo in ameliorating aged-related defects in differentiation, barrier homeostasis and skin/systemic inflammation.
    Barrier Function of Mammalian Skin Gordon Research Conference
    NIH R13AR061255May 1, 2011 - Apr 30, 2012
    Role: Principal Investigator
    Aging Stratum Corneum pH and Barrier Function
    NIH R01AG028492Sep 1, 2008 - Jul 31, 2014
    Role: Principal Investigator
    ATP2A2-Regulated Keretinocyted Ca2+ Signaling Mechanisms
    NIH R01AR051930Dec 1, 2004 - Jan 31, 2020
    Role: Principal Investigator
    NIH R29AR044341Aug 1, 1997 - Jun 30, 2003
    Role: Principal Investigator
    NIH K08AR001853Jan 15, 1991 - Dec 31, 1995
    Role: Principal Investigator
    Relationship of Keratinocyte Function to Differentiation
    NIH P01AR039448Jul 15, 1988 - Jul 31, 2010
    Role: Co-Investigator
    Laboratory for Fluorescence Dynamics
    NIH P41RR003155Jun 30, 2016
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Restoring Endoplasmic Reticulum Calcium Stores in Aged Epidermis Improves the Epidermal Calcium Gradient and Enhances FLG Expression. J Invest Dermatol. 2023 Nov 28. Celli A, Pitchford M, Lu N, Mayes AE, Evans RL, Mauro TM. PMID: 38036290.
      View in: PubMed   Mentions:    Fields:    
    2. Link between the skin and autism spectrum disorder. Front Psychiatry. 2023; 14:1265472. Man MQ, Yang S, Mauro TM, Zhang G, Zhu T. PMID: 37920540; PMCID: PMC10619695.
      View in: PubMed   Mentions:
    3. Association of Epidermal Biophysical Properties with Obesity and Its Implications. Skin Pharmacol Physiol. 2023; 36(4):165-173. Zhu T, Yang S, Mauro TM, Man MQ. PMID: 37640014.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Sodium in the skin: a summary of the physiology and a scoping review of disease associations. Clin Exp Dermatol. 2023 Jul 07; 48(7):733-743. Chattopadhyay A, Tully J, Shan J, Sheikh S, Ohliger M, Gordon JW, Mauro T, Abuabara K. PMID: 36970766.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    5. Link between obesity and atopic dermatitis: Does obesity predispose to atopic dermatitis, or vice versa? Exp Dermatol. 2023 07; 32(7):975-985. Yang S, Zhu T, Wakefield JS, Mauro TM, Elias PM, Man MQ. PMID: 37029451; PMCID: PMC10524376.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Skin Barrier Function and Cognition among Older Adults. J Invest Dermatol. 2023 06; 143(6):1085-1087. Kim RW, An Y, Zukley L, Ferrucci L, Mauro T, Yaffe K, Resnick SM, Abuabara K. PMID: 36641132.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. FLG Deficiency in Mice Alters the Early-Life CD4+ T-Cell Response to Skin Commensal Bacteria. J Invest Dermatol. 2023 05; 143(5):790-800.e12. Gonzalez JR, Celli A, Weckel A, Dhariwala MO, Merana GR, Ojewumi OT, Okoro J, Dwyer LR, Tran VM, Meyer JM, Mauro TM, Scharschmidt TC. PMID: 36496196.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Skin and bone crosstalk during aging. Nat Aging. 2022 10; 2(10):874-875. Mauro T, Bikle D. PMID: 37118286.
      View in: PubMed   Mentions:
    9. ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization. J Invest Dermatol. 2023 02; 143(2):332-335.e4. Meyer JM, Vávrová K, Radner FPW, Schneider H, Dick A, Mauro TM, Elias PM. PMID: 36116510.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    10. Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease. J Diabetes. 2022 Sep; 14(9):586-595. Man MQ, Wakefield JS, Mauro TM, Elias PM. PMID: 36043448; PMCID: PMC9512766.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    11. The link between cutaneous inflammation and cognitive impairment. J Eur Acad Dermatol Venereol. 2022 Oct; 36(10):1705-1712. Wen S, Elias PM, Wakefield JS, Mauro TM, Man MQ. PMID: 35748522; PMCID: PMC9481668.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    12. Classification of human chronic inflammatory skin disease based on single-cell immune profiling. Sci Immunol. 2022 04 15; 7(70):eabl9165. Liu Y, Wang H, Taylor M, Cook C, Martínez-Berdeja A, North JP, Harirchian P, Hailer AA, Zhao Z, Ghadially R, Ricardo-Gonzalez RR, Grekin RC, Mauro TM, Kim E, Choi J, Purdom E, Cho RJ, Cheng JB. PMID: 35427179; PMCID: PMC9301819.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    13. Regulatory Role of Nitric Oxide in Cutaneous Inflammation. Inflammation. 2022 Jun; 45(3):949-964. Man MQ, Wakefield JS, Mauro TM, Elias PM. PMID: 35094214.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    14. Epidermal Basement Membrane Substitutes for Bioengineering of Human Epidermal Equivalents. JID Innov. 2022 Mar; 2(2):100083. Kolundzic N, Khurana P, Crumrine D, Celli A, Mauro TM, Ilic D. PMID: 35199088; PMCID: PMC8844655.
      View in: PubMed   Mentions: 2  
    15. Role of nitric oxide in regulating epidermal permeability barrier function. Exp Dermatol. 2022 03; 31(3):290-298. Man MQ, Wakefield JS, Mauro TM, Elias PM. PMID: 34665906; PMCID: PMC8897205.
      View in: PubMed   Mentions: 12     Fields:    
    16. Ode to Salt: Commentary on "Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity". J Invest Dermatol. 2022 01; 142(1):16-17. Mauro TM. PMID: 34565562; PMCID: PMC8740904.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    17. Decreased Calcium-Sensing Receptor Expression Controls Calcium Signaling and Cell-To-Cell Adhesion Defects in Aged Skin. J Invest Dermatol. 2021 11; 141(11):2577-2586. Celli A, Tu CL, Lee E, Bikle DD, Mauro TM. PMID: 33862069; PMCID: PMC8526647.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    18. Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking. Am J Pathol. 2021 05; 191(5):921-929. Meyer JM, Crumrine D, Schneider H, Dick A, Schmuth M, Gruber R, Radner FPW, Grond S, Wakefield JS, Mauro TM, Elias PM. PMID: 33607042; PMCID: PMC8132177.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    19. CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress. Br J Dermatol. 2021 07; 185(1):147-152. Meyer JM, Lee E, Celli A, Park K, Cho R, Lambert W, Pitchford M, Gordon M, Tsai K, Cleaver J, Arron ST, Mauro TM. PMID: 33393080.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. CERKL is Upregulated in Cutaneous Squamous Cell Carcinoma and Maintains Cellular Sphingolipids and Resistance to Oxidative Stress. Br J Dermatol. 2020 Dec 03. Meyer JM, Lee E, Celli A, Park K, Cho R, Lambert W, Pitchford M, Gordon M, Tsai K, Cleaver J, Arron ST, Mauro TM. PMID: 33270220; PMCID: PMC8172666.
      View in: PubMed   Mentions: 1     Fields:    
    21. Mutations in 3β-hydroxysteroid-δ8, δ7-isomerase paradoxically benefit epidermal permeability barrier homeostasis in mice. Exp Dermatol. 2021 03; 30(3):384-389. Dang E, Man G, Lee D, Crumrine DA, Mauro TM, Elias PM, Man MQ. PMID: 33205489; PMCID: PMC8754084.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    22. Markers for Ca++ -induced terminal differentiation of keratinocytes in vitro under defined conditions. Exp Dermatol. 2020 12; 29(12):1238-1242. Jeriha J, Kolundzic N, Khurana P, Gordon M, Celli A, Mauro TM, Ilic D. PMID: 32978827.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Inducible nitric oxide synthase is required for epidermal permeability barrier homeostasis in mice. Exp Dermatol. 2020 10; 29(10):1027-1032. Dang E, Man G, Zhang J, Lee D, Mauro TM, Elias PM, Man MQ. PMID: 32794261; PMCID: PMC8754083.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes. ACS Nano. 2020 10 27; 14(10):13192-13202. Huang X, Shi X, Hansen ME, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA. PMID: 32940450; PMCID: PMC7606830.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    25. Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation. iScience. 2020 Oct 23; 23(10):101582. Liu Y, Cook C, Sedgewick AJ, Zhang S, Fassett MS, Ricardo-Gonzalez RR, Harirchian P, Kashem SW, Hanakawa S, Leistico JR, North JP, Taylor MA, Zhang W, Man MQ, Charruyer A, Beliakova-Bethell N, Benz SC, Ghadially R, Mauro TM, Kaplan DH, Kabashima K, Choi J, Song JS, Cho RJ, Cheng JB. PMID: 33205009; PMCID: PMC7648132.
      View in: PubMed   Mentions: 17  
    26. Perspective and Consensus Opinion: Good Practices for Using Organotypic Skin and Epidermal Equivalents in Experimental Dermatology Research. J Invest Dermatol. 2021 01; 141(1):203-205. van den Bogaard E, Ilic D, Dubrac S, Tomic-Canic M, Bouwstra J, Celli A, Mauro T, 2019 Barrier Function of Mammalian Skin Gordon Research Conference, Waterville Valley, New Hampshire. PMID: 32450074; PMCID: PMC7680418.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Aging-associated alterations in epidermal function and their clinical significance. Aging (Albany NY). 2020 03 27; 12(6):5551-5565. Wang Z, Man MQ, Li T, Elias PM, Mauro TM. PMID: 32217811; PMCID: PMC7138575.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    28. Ischemic Fasciitis Mimicking A Lipoma. Dermatol Surg. 2020 03; 46(3):427-430. Saeed L, Bahrani E, Lauw MIS, Tabatabai ZL, Arron ST, Mauro TM. PMID: 30789504.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Botulinum toxin type A suppresses pro-fibrotic effects via the JNK signaling pathway in hypertrophic scar fibroblasts. Arch Dermatol Res. 2019 Dec; 311(10):807-814. Park GS, An MK, Yoon JH, Park SS, Koh SH, Mauro TM, Cho EB, Park EJ, Kim KH, Kim KJ. PMID: 31501922.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    30. Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A. Stem Cell Res. 2019 08; 39:101527. Kolundzic N, Khurana P, Devito L, Jeriha J, Marx J, Hobbs C, Wong XFCC, Common JEA, Liovic M, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D. PMID: 31408836.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. The pathological role of Wnt5a in psoriasis and psoriatic arthritis. J Cell Mol Med. 2019 09; 23(9):5876-5883. Tian F, Mauro TM, Li Z. PMID: 31313518; PMCID: PMC6714168.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    32. Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A. Stem Cell Res. 2019 07; 38:101462. Kolundzic N, Khurana P, Devito L, Donne M, Hobbs C, Jeriha J, Wong XFCC, Common JAE, Lane EB, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D. PMID: 31103941.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. Topical applications of an emollient reduce circulating pro-inflammatory cytokine levels in chronically aged humans: a pilot clinical study. J Eur Acad Dermatol Venereol. 2019 Nov; 33(11):2197-2201. Ye L, Mauro TM, Dang E, Wang G, Hu LZ, Yu C, Jeong S, Feingold K, Elias PM, Lv CZ, Man MQ. PMID: 30835878; PMCID: PMC6728229.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    34. A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes. J Invest Dermatol. 2019 06; 139(6):1264-1273. Harirchian P, Lee J, Hilz S, Sedgewick AJ, Perez White BE, Kesling MJ, Mully T, Golovato J, Gray M, Mauro TM, Purdom E, Kim EA, Sbitany H, Bhutani T, Vaske CJ, Benz SC, Cho RJ, Cheng JB. PMID: 30543901; PMCID: PMC6642632.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    35. Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope. J Invest Dermatol. 2019 04; 139(4):760-768. Crumrine D, Khnykin D, Krieg P, Man MQ, Celli A, Mauro TM, Wakefield JS, Menon G, Mauldin E, Miner JH, Lin MH, Brash AR, Sprecher E, Radner FPW, Choate K, Roop D, Uchida Y, Gruber R, Schmuth M, Elias PM. PMID: 30471252.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    36. Calcium-Sensing Receptor Regulates Epidermal Intracellular Ca2+ Signaling and Re-Epithelialization after Wounding. J Invest Dermatol. 2019 04; 139(4):919-929. Tu CL, Celli A, Mauro T, Chang W. PMID: 30404020; PMCID: PMC6431556.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    37. Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution. Cell Rep. 2018 10 23; 25(4):871-883. Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu SS, Gray JW, Purdom E, Paus R, Vaske CJ, Benz SC, Song JS, Cho RJ. PMID: 30355494; PMCID: PMC6367716.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
    38. A data mining paradigm for identifying key factors in biological processes using gene expression data. Sci Rep. 2018 06 13; 8(1):9083. Li J, Zheng L, Uchiyama A, Bin L, Mauro TM, Elias PM, Pawelczyk T, Sakowicz-Burkiewicz M, Trzeciak M, Leung DYM, Morasso MI, Yu P. PMID: 29899432; PMCID: PMC5998123.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    39. Mohs Micrographic Surgery in the Veterans Health Administration. Fed Pract. 2018 Feb; 35(Suppl 1):S38-S43. Tam A, Yuan JT, Mauro TM, Dellavalle RP, Arron ST. PMID: 30766388; PMCID: PMC6375518.
      View in: PubMed   Mentions:
    40. Warfarin-Associated Nonuremic Calciphylaxis. JAMA Dermatol. 2017 03 01; 153(3):309-314. Yu WY, Bhutani T, Kornik R, Pincus LB, Mauro T, Rosenblum MD, Fox LP. PMID: 28099971; PMCID: PMC5703198.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    41. Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines. J Invest Dermatol. 2017 06; 137(6):1277-1285. Hu L, Mauro TM, Dang E, Man G, Zhang J, Lee D, Wang G, Feingold KR, Elias PM, Man MQ. PMID: 28115059; PMCID: PMC5441930.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    42. Voriconazole exposure regulates distinct cell-cycle and terminal differentiation pathways in primary human keratinocytes. Br J Dermatol. 2017 03; 176(3):816-820. Mansh M, Ing L, Dimon M, Celli A, Mauro TM, Arron ST. PMID: 27373453; PMCID: PMC5215362.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    43. Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin. Stem Cells Dev. 2016 09 15; 25(18):1366-75. Petrova A, Capalbo A, Jacquet L, Hazelwood-Smith S, Dafou D, Hobbs C, Arno M, Farcomeni A, Devito L, Badraiq H, Simpson M, McGrath JA, Di WL, Cheng JB, Mauro TM, Ilic D. PMID: 27460132; PMCID: PMC5035378.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    44. Endoplasmic Reticulum Calcium Regulates Epidermal Barrier Response and Desmosomal Structure. J Invest Dermatol. 2016 09; 136(9):1840-1847. Celli A, Crumrine D, Meyer JM, Mauro TM. PMID: 27255610; PMCID: PMC5070468.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    45. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep; 79(3):229-34. Jeong SK, Kim YI, Shin KO, Kim BW, Lee SH, Jeon JE, Kim HJ, Lee YM, Mauro TM, Elias PM, Uchida Y, Park K. PMID: 26113114; PMCID: PMC4624019.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    46. Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17F. FEBS Lett. 2015 Jul 08; 589(15):1904-10. Bosen F, Celli A, Crumrine D, vom Dorp K, Ebel P, Jastrow H, Dörmann P, Winterhager E, Mauro T, Willecke K. PMID: 26070424; PMCID: PMC4741282.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    47. UVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo. Exp Dermatol. 2015 May; 24(5):370-6. Tiganescu A, Hupe M, Jiang YJ, Celli A, Uchida Y, Mauro TM, Bikle DD, Elias PM, Holleran WM. PMID: 25739654; PMCID: PMC6365099.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    48. Nanotopography facilitates in vivo transdermal delivery of high molecular weight therapeutics through an integrin-dependent mechanism. Nano Lett. 2015 Apr 08; 15(4):2434-41. Walsh L, Ryu J, Bock S, Koval M, Mauro T, Ross R, Desai T. PMID: 25790174; PMCID: PMC4478088.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    49. Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency. Am J Pathol. 2015 Apr; 185(4):1012-21. Gruber R, Sugarman JL, Crumrine D, Hupe M, Mauro TM, Mauldin EA, Thyssen JP, Brandner JM, Hennies HC, Schmuth M, Elias PM. PMID: 25660180; PMCID: PMC4380844.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    50. Lowered humidity produces human epidermal equivalents with enhanced barrier properties. Tissue Eng Part C Methods. 2015 Jan; 21(1):15-22. Sun R, Celli A, Crumrine D, Hupe M, Adame LC, Pennypacker SD, Park K, Uchida Y, Feingold KR, Elias PM, Ilic D, Mauro TM. PMID: 24803151; PMCID: PMC4291214.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    51. Topical hesperidin enhances epidermal function in an aged murine model. J Invest Dermatol. 2015 Apr; 135(4):1184-1187. Man G, Mauro TM, Zhai Y, Kim PL, Cheung C, Hupe M, Crumrine D, Elias PM, Man MQ. PMID: 25402552; PMCID: PMC4366273.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    52. Topical hesperidin prevents glucocorticoid-induced abnormalities in epidermal barrier function in murine skin. Exp Dermatol. 2014 Sep; 23(9):645-51. Man G, Mauro TM, Kim PL, Hupe M, Zhai Y, Sun R, Crumrine D, Cheung C, Nuno-Gonzalez A, Elias PM, Man MQ. PMID: 24980072; PMCID: PMC4499456.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    53. Endoplasmic reticulum calcium, stress, and cell-to-cell adhesion. J Invest Dermatol. 2014 Jul; 134(7):1800-1801. Mauro T. PMID: 24924761; PMCID: PMC4083462.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    54. Ibrutinib rash in a patient with 17p del chronic lymphocytic leukemia. Am J Hematol. 2015 Feb; 90(2):179. Mannis G, Wu D, Dea T, Mauro T, Hsu G. PMID: 24890909; PMCID: PMC4548957.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    55. Calcium, Orai1, and epidermal proliferation. J Invest Dermatol. 2014 Jun; 134(6):1506-1508. Bikle DD, Mauro TM. PMID: 24825060; PMCID: PMC4023905.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    56. 3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports. 2014 May 06; 2(5):675-89. Petrova A, Celli A, Jacquet L, Dafou D, Crumrine D, Hupe M, Arno M, Hobbs C, Cvoro A, Karagiannis P, Devito L, Sun R, Adame LC, Vaughan R, McGrath JA, Mauro TM, Ilic D. PMID: 24936454; PMCID: PMC4050479.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    57. Basis for enhanced barrier function of pigmented skin. J Invest Dermatol. 2014 Sep; 134(9):2399-2407. Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias PM. PMID: 24732399; PMCID: PMC4134407.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    58. Increased glucocorticoid activation during mouse skin wound healing. J Endocrinol. 2014 Apr; 221(1):51-61. Tiganescu A, Hupe M, Uchida Y, Mauro T, Elias PM, Holleran WM. PMID: 24464022.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    59. Comparison of publication trends in dermatology among Japan, South Korea and Mainland China. BMC Dermatol. 2014 Jan 09; 14:1. Man H, Xin S, Bi W, Lv C, Mauro TM, Elias PM, Man MQ. PMID: 24405832; PMCID: PMC3893556.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    60. sPLA2 and the epidermal barrier. Biochim Biophys Acta. 2014 Mar; 1841(3):416-21. Ilic D, Bollinger JM, Gelb M, Mauro TM. PMID: 24269828; PMCID: PMC4548940.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    61. Ten-year publication trends in dermatology in mainland China. Int J Dermatol. 2014 Oct; 53(10):e438-42. Xin S, Mauro JA, Mauro TM, Elias PM, Man MQ. PMID: 23968296; PMCID: PMC3841226.
      View in: PubMed   Mentions: 2     Fields:    
    62. Local blockade of glucocorticoid activation reverses stress- and glucocorticoid-induced delays in cutaneous wound healing. Wound Repair Regen. 2013 Sep-Oct; 21(5):715-22. Youm JK, Park K, Uchida Y, Chan A, Mauro TM, Holleran WM, Elias PM. PMID: 23927023; PMCID: PMC4507432.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    63. Topical apigenin improves epidermal permeability barrier homoeostasis in normal murine skin by divergent mechanisms. Exp Dermatol. 2013 Mar; 22(3):210-5. Hou M, Sun R, Hupe M, Kim PL, Park K, Crumrine D, Lin TK, Santiago JL, Mauro TM, Elias PM, Man MQ. PMID: 23489424; PMCID: PMC3626082.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    64. Systemic retinoids in the management of ichthyoses and related skin types. Dermatol Ther. 2013 Jan-Feb; 26(1):26-38. Digiovanna JJ, Mauro T, Milstone LM, Schmuth M, Toro JR. PMID: 23384018; PMCID: PMC3884695.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    65. Topical apigenin alleviates cutaneous inflammation in murine models. Evid Based Complement Alternat Med. 2012; 2012:912028. Man MQ, Hupe M, Sun R, Man G, Mauro TM, Elias PM. PMID: 23304222; PMCID: PMC3524999.
      View in: PubMed   Mentions: 19  
    66. Overexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells. PLoS One. 2012; 7(10):e47846. Oh MC, Kim JM, Safaee M, Kaur G, Sun MZ, Kaur R, Celli A, Mauro TM, Parsa AT. PMID: 23110111; PMCID: PMC3479115.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    67. Tight junction properties change during epidermis development. Exp Dermatol. 2012 Oct; 21(10):798-801. Celli A, Zhai Y, Jiang YJ, Crumrine D, Elias PM, Feingold KR, Mauro TM. PMID: 22882565; PMCID: PMC3477265.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    68. SERCA2-controlled Ca²+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier's disease. J Invest Dermatol. 2012 Apr; 132(4):1188-95. Celli A, Mackenzie DS, Zhai Y, Tu CL, Bikle DD, Holleran WM, Uchida Y, Mauro TM. PMID: 22277942; PMCID: PMC3305850.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    69. Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17761-6. Wang NJ, Sanborn Z, Arnett KL, Bayston LJ, Liao W, Proby CM, Leigh IM, Collisson EA, Gordon PB, Jakkula L, Pennypacker S, Zou Y, Sharma M, North JP, Vemula SS, Mauro TM, Neuhaus IM, Leboit PE, Hur JS, Park K, Huh N, Kwok PY, Arron ST, Massion PP, Bale AE, Haussler D, Cleaver JE, Gray JW, Spellman PT, South AP, Aster JC, Blacklow SC, Cho RJ. PMID: 22006338; PMCID: PMC3203814.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansCells
    70. Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway. J Biol Chem. 2011 Sep 30; 286(39):34121-30. Park K, Elias PM, Oda Y, Mackenzie D, Mauro T, Holleran WM, Uchida Y. PMID: 21832078; PMCID: PMC3190812.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    71. Temporal dissection of tumorigenesis in primary cancers. Cancer Discov. 2011 Jul; 1(2):137-43. Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC, Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho RJ. PMID: 21984974; PMCID: PMC3187561.
      View in: PubMed   Mentions: 136     Fields:    Translation:Humans
    72. Acidification in the epidermis and the role of secretory phospholipases. Dermatoendocrinol. 2011 Apr; 3(2):84-90. Chan A, Mauro T. PMID: 21695017; PMCID: PMC3117007.
      View in: PubMed   Mentions: 14  
    73. A topical Chinese herbal mixture improves epidermal permeability barrier function in normal murine skin. Exp Dermatol. 2011 Mar; 20(3):285-8. Man M, Hupe M, Mackenzie D, Kim H, Oda Y, Crumrine D, Lee SH, Martin-Ezquerra G, Trullas C, Mauro TM, Feingold KR, Elias PM, Man MQ. PMID: 21323748; PMCID: PMC4548955.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    74. Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis. Arch Dermatol Res. 2011 Mar; 303(2):103-15. Behne MJ, Sanchez S, Barry NP, Kirschner N, Meyer W, Mauro TM, Moll I, Gratton E. PMID: 21193994; PMCID: PMC4548958.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    75. Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis. Br J Dermatol. 2011 Jan; 164(1):16-25. Celli A, Mackenzie DS, Crumrine DS, Tu CL, Hupe M, Bikle DD, Elias PM, Mauro TM. PMID: 20846312; PMCID: PMC3010253.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    76. Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification? J Invest Dermatol. 2010 Aug; 130(8):2141-4. Fluhr JW, Elias PM, Man MQ, Hupe M, Selden C, Sundberg JP, Tschachler E, Eckhart L, Mauro TM, Feingold KR. PMID: 20376063; PMCID: PMC4548931.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    77. The epidermal Ca(2+) gradient: Measurement using the phasor representation of fluorescent lifetime imaging. Biophys J. 2010 Mar 03; 98(5):911-21. Celli A, Sanchez S, Behne M, Hazlett T, Gratton E, Mauro T. PMID: 20197045; PMCID: PMC2830439.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    78. Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis. J Invest Dermatol. 2010 Apr; 130(4):1185-8. Gunathilake R, Schmuth M, Scharschmidt TC, Gruber R, Grabher D, Leslie KS, Maurer TA, Mauro TM, Elias PM. PMID: 19924137; PMCID: PMC4548930.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    79. Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators. J Allergy Clin Immunol. 2010 Jan; 125(1):160-9.e1-5. Hatano Y, Man MQ, Uchida Y, Crumrine D, Mauro TM, Feingold KR, Elias PM, Holleran WM. PMID: 19818482; PMCID: PMC2859962.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    80. Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes. J Invest Dermatol. 2010 Feb; 130(2):500-10. Hachem JP, Roelandt T, Schürer N, Pu X, Fluhr J, Giddelo C, Man MQ, Crumrine D, Roseeuw D, Feingold KR, Mauro T, Elias PM. PMID: 19741713; PMCID: PMC2844116.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    81. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. J Allergy Clin Immunol. 2009 Sep; 124(3):496-506, 506.e1-6. Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM. PMID: 19733297; PMCID: PMC2881668.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    82. Akt2 and SGK3 are both determinants of postnatal hair follicle development. FASEB J. 2009 Sep; 23(9):3193-202. Mauro TM, McCormick JA, Wang J, Boini KM, Ray L, Monks B, Birnbaum MJ, Lang F, Pearce D. PMID: 19433625; PMCID: PMC2735357.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    83. Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis. J Invest Dermatol. 2009 Jul; 129(7):1824-35. Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, Holleran WM. PMID: 19177139; PMCID: PMC2695850.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    84. pH-regulated mechanisms account for pigment-type differences in epidermal barrier function. J Invest Dermatol. 2009 Jul; 129(7):1719-29. Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, Sirimanna G, Feingold KR, Mauro TM, Elias PM. PMID: 19177137; PMCID: PMC2695842.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    85. Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification. J Invest Dermatol. 2009 Feb; 129(2):365-74. Fluhr JW, Man MQ, Hachem JP, Crumrine D, Mauro TM, Elias PM, Feingold KR. PMID: 18704104; PMCID: PMC4548956.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    86. Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2. Am J Pathol. 2008 Jan; 172(1):86-97. Demerjian M, Hachem JP, Tschachler E, Denecker G, Declercq W, Vandenabeele P, Mauro T, Hupe M, Crumrine D, Roelandt T, Houben E, Elias PM, Feingold KR. PMID: 18156206; PMCID: PMC2189608.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    87. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest. 2007 Nov; 117(11):3339-49. Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. PMID: 17975669; PMCID: PMC2045593.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    88. Stratum corneum acidification is impaired in moderately aged human and murine skin. J Invest Dermatol. 2007 Dec; 127(12):2847-56. Choi EH, Man MQ, Xu P, Xin S, Liu Z, Crumrine DA, Jiang YJ, Fluhr JW, Feingold KR, Elias PM, Mauro TM. PMID: 17554364.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    89. Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization. Am J Pathol. 2007 Jun; 170(6):2055-67. Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, Mauro TM. PMID: 17525272; PMCID: PMC1899430.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    90. CaR talk: the calcium receptor finds new places to park. J Invest Dermatol. 2007 May; 127(5):991-2. Mauro TM. PMID: 17435781.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    91. Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation. J Invest Dermatol. 2007 Aug; 127(8):1973-9. Aberg KM, Racz E, Behne MJ, Mauro TM. PMID: 17392835.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    92. Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J Bone Miner Res. 2007 Feb; 22(2):274-85. Bianco SD, Peng JB, Takanaga H, Suzuki Y, Crescenzi A, Kos CH, Zhuang L, Freeman MR, Gouveia CH, Wu J, Luo H, Mauro T, Brown EM, Hediger MA. PMID: 17129178; PMCID: PMC4548943.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    93. Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function. Am J Physiol Regul Integr Comp Physiol. 2006 Dec; 291(6):R1657-62. Choi EH, Demerjian M, Crumrine D, Brown BE, Mauro T, Elias PM, Feingold KR. PMID: 16857896.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    94. Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome. J Invest Dermatol. 2006 Jul; 126(7):1609-21. Hachem JP, Wagberg F, Schmuth M, Crumrine D, Lissens W, Jayakumar A, Houben E, Mauro TM, Leonardsson G, Brattsand M, Egelrud T, Roseeuw D, Clayman GL, Feingold KR, Williams ML, Elias PM. PMID: 16601670.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    95. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Exp Dermatol. 2006 Mar; 15(3):154-60. Demerjian M, Man MQ, Choi EH, Brown BE, Crumrine D, Chang S, Mauro T, Elias PM, Feingold KR. PMID: 16480422.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    96. Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK. Oncogene. 2006 Feb 16; 25(7):1081-9. Essayem S, Kovacic-Milivojevic B, Baumbusch C, McDonagh S, Dolganov G, Howerton K, Larocque N, Mauro T, Ramirez A, Ramos DM, Fisher SJ, Jorcano JL, Beggs HE, Reichardt LF, Ilic D. PMID: 16247468; PMCID: PMC2710133.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    97. Activity of the hSPCA1 Golgi Ca2+ pump is essential for Ca2+-mediated Ca2+ response and cell viability in Darier disease. J Cell Sci. 2006 Feb 15; 119(Pt 4):671-9. Foggia L, Aronchik I, Aberg K, Brown B, Hovnanian A, Mauro TM. PMID: 16467572.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    98. Extracellular pH Controls NHE1 expression in epidermis and keratinocytes: implications for barrier repair. J Invest Dermatol. 2005 Oct; 125(4):790-7. Hachem JP, Behne M, Aronchik I, Demerjian M, Feingold KR, Elias PM, Mauro TM. PMID: 16185280.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    99. Sarcoidosis associated with pegylated interferon alfa and ribavirin treatment for chronic hepatitis C: a case report and review of the literature. Arch Dermatol. 2005 Jul; 141(7):865-8. Hurst EA, Mauro T. PMID: 16027302.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    100. Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy. AIDS. 2004 Aug 20; 18(12):1742-4. Mafong DD, Lee GA, Yu S, Tien P, Mauro T, Grunfeld C. PMID: 15280791.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    101. Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol Biol Cell. 2004 Sep; 15(9):4278-88. McCormick JA, Feng Y, Dawson K, Behne MJ, Yu B, Wang J, Wyatt AW, Henke G, Grahammer F, Mauro TM, Lang F, Pearce D. PMID: 15240817; PMCID: PMC515358.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    102. Functional consequences of a neutral pH in neonatal rat stratum corneum. J Invest Dermatol. 2004 Jul; 123(1):140-51. Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M, Haftek M, Serre G, Crumrine D, Mauro TM, Elias PM, Feingold KR. PMID: 15191554.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    103. Analysis: blood glucose monitoring: making the possible practical. Diabetes Technol Ther. 2004 Jun; 6(3):368-9. Mauro T. PMID: 15198840.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    104. Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum. J Invest Dermatol. 2004 Feb; 122(2):320-9. Fluhr JW, Behne MJ, Brown BE, Moskowitz DG, Selden C, Mao-Qiang M, Mauro TM, Elias PM, Feingold KR. PMID: 15009712.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    105. Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes. J Invest Dermatol. 2003 Oct; 121(4):681-7. Aronchik I, Behne MJ, Leypoldt L, Crumrine D, Epstein E, Ikeda S, Mizoguchi M, Bench G, Pozzan T, Mauro T. PMID: 14632182.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    106. Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores. J Invest Dermatol. 2003 Oct; 121(4):688-94. Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM. PMID: 14632183.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    107. 'The discovery channel': CRAC'king the code of calcium influx. J Invest Dermatol. 2003 Jul; 121(1):IX-X. Mauro T. PMID: 12839592.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    108. Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol. 2003 Jun; 120(6):998-1006. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM. PMID: 12787127.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    109. Defective cyclic guanosine monophosphate-gated calcium channels and the pathogenesis of psoriasis. Acta Derm Venereol. 2003; 83(6):414-8. McKenzie RC, Oda Y, Szepietowski JC, Behne MJ, Mauro T. PMID: 14690334.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    110. NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging. J Biol Chem. 2002 Dec 06; 277(49):47399-406. Behne MJ, Meyer JW, Hanson KM, Barry NP, Murata S, Crumrine D, Clegg RW, Gratton E, Holleran WM, Elias PM, Mauro TM. PMID: 12221084.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    111. Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation. J Cell Physiol. 2002 Jul; 192(1):45-54. Komuves L, Oda Y, Tu CL, Chang WH, Ho-Pao CL, Mauro T, Bikle DD. PMID: 12115735.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    112. The ENaC channel is required for normal epidermal differentiation. J Invest Dermatol. 2002 Apr; 118(4):589-94. Mauro T, Guitard M, Behne M, Oda Y, Crumrine D, Komuves L, Rassner U, Elias PM, Hummler E. PMID: 11918703.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    113. Treatment of an ulcerated hemangioma with recombinant platelet-derived growth factor. Arch Dermatol. 2002 Mar; 138(3):314-6. Sugarman JL, Mauro TM, Frieden IJ. PMID: 11902979.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    114. Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation. Dev Dyn. 2000 Aug; 218(4):636-47. Kömüves LG, Shen WF, Kwong A, Stelnicki E, Rozenfeld S, Oda Y, Blink A, Krishnan K, Lau B, Mauro T, Largman C. PMID: 10906782.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    115. The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation. J Biol Chem. 2000 Jan 14; 275(2):1183-90. Oda Y, Tu CL, Chang W, Crumrine D, Kömüves L, Mauro T, Elias PM, Bikle DD. PMID: 10625662.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    116. Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease. Nat Genet. 2000 Jan; 24(1):61-5. Hu Z, Bonifas JM, Beech J, Bench G, Shigihara T, Ogawa H, Ikeda S, Mauro T, Epstein EH. PMID: 10615129.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    117. Epithelial sodium channels are upregulated during epidermal differentiation. J Invest Dermatol. 1999 Nov; 113(5):796-801. Oda Y, Imanzahrai A, Kwong A, Kömüves L, Elias PM, Largman C, Mauro T. PMID: 10571736.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    118. Acute barrier perturbation abolishes the Ca2+ and K+ gradients in murine epidermis: quantitative measurement using PIXE. J Invest Dermatol. 1998 Dec; 111(6):1198-201. Mauro T, Bench G, Sidderas-Haddad E, Feingold K, Elias P, Cullander C. PMID: 9856840.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    119. The secretory granular cell: the outermost granular cell as a specialized secretory cell. J Investig Dermatol Symp Proc. 1998 Aug; 3(2):87-100. Elias PM, Cullander C, Mauro T, Rassner U, Kömüves L, Brown BE, Menon GK. PMID: 9734820.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    120. Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing. Arch Dermatol Res. 1998 Apr; 290(4):215-22. Mauro T, Holleran WM, Grayson S, Gao WN, Man MQ, Kriehuber E, Behne M, Feingold KR, Elias PM. PMID: 9617442.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    121. Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent. J Invest Dermatol. 1998 Apr; 110(4):399-404. Elias PM, Nau P, Hanley K, Cullander C, Crumrine D, Bench G, Sideras-Haddad E, Mauro T, Williams ML, Feingold KR. PMID: 9540982.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    122. Alternatively spliced forms of the cGMP-gated channel in human keratinocytes. FEBS Lett. 1997 Sep 01; 414(1):140-5. Oda Y, Timpe LC, McKenzie RC, Sauder DN, Largman C, Mauro T. PMID: 9305748.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    123. Keratinocyte K+ channels mediate Ca2+-induced differentiation. J Invest Dermatol. 1997 Jun; 108(6):864-70. Mauro T, Dixon DB, Komuves L, Hanley K, Pappone PA. PMID: 9182812.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    124. Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice. Exp Dermatol. 1997 Feb; 6(1):36-40. Mao-Qiang M, Mauro T, Bench G, Warren R, Elias PM, Feingold KR. PMID: 9067705.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    125. Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation. J Invest Dermatol. 1996 Sep; 107(3):412-8. Grando SA, Horton RM, Mauro TM, Kist DA, Lee TX, Dahl MV. PMID: 8751979.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    126. Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor. J Clin Invest. 1996 Feb 15; 97(4):1085-93. Bikle DD, Ratnam A, Mauro T, Harris J, Pillai S. PMID: 8613532; PMCID: PMC507156.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    127. Disseminated cutaneous Cryptococcus clinically mimicking basal cell carcinoma. Dermatol Surg. 1995 Nov; 21(11):992-3. Murakawa GJ, Mauro TM, Egbert B. PMID: 7582844.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    128. Treatment of leg ulcers with cultured epithelial autografts: clinical study and case reports. Ostomy Wound Manage. 1995 Sep; 41(8):48-50, 52, 54-60. Límová M, Mauro T. PMID: 7546120.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    129. Amiloride blocks a keratinocyte nonspecific cation channel and inhibits Ca(++)-induced keratinocyte differentiation. J Invest Dermatol. 1995 Aug; 105(2):203-8. Mauro T, Dixon DB, Hanley K, Isseroff RR, Pappone PA. PMID: 7543548.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    130. Treatment of pyoderma gangrenosum with cultured keratinocyte autografts. J Dermatol Surg Oncol. 1994 Dec; 20(12):833-6. Límová M, Mauro T. PMID: 7798418.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    131. A role for ions in barrier recovery after acute perturbation. J Invest Dermatol. 1994 Jun; 102(6):976-9. Lee SH, Elias PM, Feingold KR, Mauro T. PMID: 8006464.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    132. Mal de Meleda in a Laotian family. Int J Dermatol. 1993 Aug; 32(8):602-4. Chotzen VA, Starr JC, Mauro TM. PMID: 8407080.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    133. Ion channels are linked to differentiation in keratinocytes. J Membr Biol. 1993 Mar; 132(3):201-9. Mauro TM, Isseroff RR, Lasarow R, Pappone PA. PMID: 7684087.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    134. Acrodermatitis enteropathica in a patient with the acquired immunodeficiency syndrome. Arch Dermatol. 1992 Mar; 128(3):415-7. Reichel M, Mauro TM, Ziboh VA, Huntley AC, Fletcher MP. PMID: 1550386.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    135. Autologous skin grafts for leg ulcers. West J Med. 1992 Feb; 156(2):191. Mauro TM. PMID: 1536074; PMCID: PMC1003201.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    136. Urticaria and hepatitis C. Lancet. 1990 Sep 29; 336(8718):822-3. Reichel M, Mauro TM. PMID: 1976189.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    137. Extracellular calcium affects the membrane currents of cultured human keratinocytes. J Cell Physiol. 1990 Apr; 143(1):13-20. Mauro TM, Pappone PA, Isseroff RR. PMID: 1690740.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    138. Establishment of a human cutaneous T-cell lymphoma in C.B-17 SCID mice. J Invest Dermatol. 1990 Mar; 94(3):381-4. Charley MR, Tharp M, Locker J, Deng JS, Goslen JB, Mauro T, McCoy P, Abell E, Jegasothy B. PMID: 2307857.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    139. Linear granuloma annulare. J Am Acad Dermatol. 1989 Nov; 21(5 Pt 2):1138-41. Harpster EF, Mauro T, Barr RJ. PMID: 2808847.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    140. Effects of TPA on short-circuit current across frog skin. Am J Physiol. 1987 Feb; 252(2 Pt 1):C173-8. Mauro T, O'Brien TG, Civan MM. PMID: 3103464.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    141. Effects of tumor promoters on sodium ion transport across frog skin. Am J Physiol. 1985 May; 248(5 Pt 1):C457-65. Civan MM, Rubenstein D, Mauro T, O'Brien TG. PMID: 2986464.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    142. Postcapillary pH disequilibrium after gas exchange in isolated perfused liver. J Appl Physiol Respir Environ Exerc Physiol. 1979 Nov; 47(5):1079-83. O'Brasky JE, Mauro T, Crandall ED. PMID: 41831.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
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