Raymond Cho, MD, PhD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
Address2340 Sutter Street
San Francisco CA 94115
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.2005School of Medicine
    Stanford UniversityPh.D.2003Department of Genetics
    Collapse Awards and Honors
    Sohana Research Foundation2015  - 2017Sohana Research Scholar
    Samsung Electronics2013  - 2015SAIT Global Research Outreach Award
    American Skin Association 2012  - 2013Abby S. & Howard P. Milstein Scholar in Melanoma
    Dermatology Foundation2009  - 2012Career Development Award
    American Academy of Dermatology2012Young Investigator Award

    Collapse Overview 
    Collapse Overview
    An NIH-funded physician-scientist, Dr. Cho focuses on cancer evolution and heritable genetics, using emerging imaging and deep sequencing technologies in multicenter collaborations.

    Dr. Cho received both his MD and his PhD in Genetics from the Stanford University School of Medicine. There he collaboratively led the earliest demonstrations of transcriptional profiling, genetic screens, and SNP-based mapping on a whole-genome scale. He subsequently co-founded Ingenuity Systems, a privately funded genetic content and software concern wholly acquired by Qiagen in 2013.

    Dr. Cho has been recognized with the Samsung Global Research Outreach Award and the American Academy of Dermatology Young Investigator Award. He was the Abby S. & Howard P. Milstein Research Scholar in Melanoma and received a Career Development Award from the Dermatology Foundation. In his spare time he cultivates a phylogenetic tree on which shawarma and tacos al pastor uneasily share a branch.

    Collapse ORNG Applications 
    Collapse Global Health
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. North JP, Golovato J, Vaske CJ, Sanborn JZ, Nguyen A, Wu W, Goode B, Stevers M, McMullen K, Perez White BE, Collisson EA, Bloomer M, Solomon DA, Benz SC, Cho R. Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma. Nat Commun. 2018 May 14; 9(1):1894. PMID: 29760388.
      View in: PubMed
    2. Cheng JB, Cho R. Emergence and Evolution of Mutational Hotspots in Sun-Damaged Skin. J Invest Dermatol. 2018 Jan; 138(1):16-17. PMID: 29273145.
      View in: PubMed
    3. Fong K, Bailey CV, Tuttle P, Cunningham B, McGrath JA, Cho R. Questioning the Clinical Utility of Exome Sequencing in Developing Countries. Pediatr Dermatol. 2017 Jan; 34(1):e32-e34. PMID: 27874213.
      View in: PubMed
    4. Cho R, Collisson EA. Election 2016: Voting on Variants. Cancer Discov. 2016 07; 6(7):694-6. PMID: 27371574.
      View in: PubMed
    5. Schulman JM, Oh DH, Sanborn JZ, Pincus L, McCalmont TH, Cho R. Multiple Hereditary Infundibulocystic Basal Cell Carcinoma Syndrome Associated With a Germline SUFU Mutation. JAMA Dermatol. 2016 Mar; 152(3):323-7. PMID: 26677003.
      View in: PubMed
    6. Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, Cho R, Murali R, Bastian BC. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nat Genet. 2015 Oct; 47(10):1194-9. PMID: 26343386; PMCID: PMC4589486.
    7. Sanborn JZ, Chung J, Purdom E, Wang NJ, Kakavand H, Wilmott JS, Butler T, Thompson JF, Mann GJ, Haydu LE, Saw RP, Busam KJ, Lo RS, Collisson EA, Hur JS, Spellman PT, Cleaver JE, Gray JW, Huh N, Murali R, Scolyer RA, Bastian BC, Cho R. Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):10995-1000. PMID: 26286987; PMCID: PMC4568214.
    8. Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, Umbricht C, Sukumar S, Seth P, Sukhatme VP, Jakkula LR, Lu Y, Mills GB, Cho R, Collisson EA, Van't Veer LJ, Spellman PT, Gray JW. Erratum to: Modeling precision treatment of breast cancer. Genome Biol. 2015 May 12; 16:95. PMID: 25962591; PMCID: PMC4426644.
    9. Zheng CL, Wang NJ, Chung J, Moslehi H, Sanborn JZ, Hur JS, Collisson EA, Vemula SS, Naujokas A, Chiotti KE, Cheng JB, Fassihi H, Blumberg AJ, Bailey CV, Fudem GM, Mihm FG, Cunningham BB, Neuhaus IM, Liao W, Oh DH, Cleaver JE, LeBoit PE, Costello JF, Lehmann AR, Gray JW, Spellman PT, Arron ST, Huh N, Purdom E, Cho R. Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes. Cell Rep. 2014 Nov 20; 9(4):1228-34. PMID: 25456125; PMCID: PMC4254608.
    10. Dimon MT, Wood HM, Rabbitts PH, Liao W, Cho R, Arron ST. No evidence for integrated viral DNA in the genome sequence of cutaneous squamous cell carcinoma. J Invest Dermatol. 2014 Jul; 134(7):2055-2057. PMID: 24480882; PMCID: PMC4057961.
    11. Purdom E, Ho C, Grasso CS, Quist MJ, Cho R, Spellman P. Methods and challenges in timing chromosomal abnormalities within cancer samples. Bioinformatics. 2013 Dec 15; 29(24):3113-20. PMID: 24064421; PMCID: PMC3842754.
    12. Kluk MJ, Ashworth T, Wang H, Knoechel B, Mason EF, Morgan EA, Dorfman D, Pinkus G, Weigert O, Hornick JL, Chirieac LR, Hirsch M, Oh DJ, South AP, Leigh IM, Pourreyron C, Cassidy AJ, Deangelo DJ, Weinstock DM, Krop IE, Dillon D, Brock JE, Lazar AJ, Peto M, Cho R, Stoeck A, Haines BB, Sathayanrayanan S, Rodig S, Aster JC. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS One. 2013; 8(6):e67306. PMID: 23825651; PMCID: PMC3688991.
    13. Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, Umbricht C, Sukumar S, Seth P, Sukhatme VP, Jakkula LR, Lu Y, Mills GB, Cho R, Collisson EA, van't Veer LJ, Spellman PT, Gray JW. Modeling precision treatment of breast cancer. Genome Biol. 2013; 14(10):R110. PMID: 24176112; PMCID: PMC3937590.
    14. Cho R, Simpson MA, McGrath JA. Next-generation diagnostics for genodermatoses. J Invest Dermatol. 2012 Nov 15; 132(E1):E27-8. PMID: 23154629.
      View in: PubMed
    15. Cho R, Simpson MA, McGrath JA. Next-Generation Diagnostics for Genodermatoses. J Invest Dermatol. 2012 Nov; 132 Suppl 3:E27-8. PMID: 26875439.
      View in: PubMed
    16. Collisson EA, Cho R. Histology, anatomy, or geography? Exome sequencing begins to delineate somatic mutational differences in esophageal cancer. Cancer Discov. 2012 Oct; 2(10):870-1. PMID: 23071029.
      View in: PubMed
    17. Collisson EA, Cho R, Gray JW. What are we learning from the cancer genome? Nat Rev Clin Oncol. 2012 Nov; 9(11):621-30. PMID: 22965149; PMCID: PMC4169265.
    18. Cho R, McCalmont TH, Ai WZ, Fox LP, Treseler P, Pincus LB. Use of an expanded immunohistochemical panel to distinguish cutaneous Hodgkin lymphoma from histopathologic imitators. J Cutan Pathol. 2012 Jun; 39(6):651-8. PMID: 22324490.
      View in: PubMed
    19. South AP, Cho R, Aster JC. The double-edged sword of Notch signaling in cancer. Semin Cell Dev Biol. 2012 Jun; 23(4):458-64. PMID: 22309843; PMCID: PMC3360804.
    20. Cheng JB, Cho R. Genetics and epigenetics of the skin meet deep sequence. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):923-32. PMID: 22237701; PMCID: PMC4099064.
    21. Wang NJ, Sanborn Z, Arnett KL, Bayston LJ, Liao W, Proby CM, Leigh IM, Collisson EA, Gordon PB, Jakkula L, Pennypacker S, Zou Y, Sharma M, North JP, Vemula SS, Mauro TM, Neuhaus IM, Leboit PE, Hur JS, Park K, Huh N, Kwok PY, Arron ST, Massion PP, Bale AE, Haussler D, Cleaver JE, Gray JW, Spellman PT, South AP, Aster JC, Blacklow SC, Cho R. Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17761-6. PMID: 22006338; PMCID: PMC3203814.
    22. Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz G, Cibulskis K, Aster JC, Huang H, Purdom E, Li J, Bolund L, Arron ST, Gray JW, Spellman PT, Cho R. Temporal dissection of tumorigenesis in primary cancers. Cancer Discov. 2011 Jul; 1(2):137-43. PMID: 21984974; PMCID: PMC3187561.
    23. Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Jun 29; 474(7353):609-15. PMID: 21720365; PMCID: PMC3163504.
    24. Cho R. Rethinking the prosaicism of mosaicism; is it in us? Exp Dermatol. 2010 Dec; 19(12):1037-9. PMID: 21132868.
      View in: PubMed
    25. Pincus LB, LeBoit PE, Goddard DS, Cho R, McCalmont TH. Marked papillary dermal edema--an unreliable discriminator between polymorphous light eruption and lupus erythematosus or dermatomyositis. J Cutan Pathol. 2010 Apr; 37(4):416-25. PMID: 20377671.
      View in: PubMed
    26. Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho R, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF. A network-based analysis of systemic inflammation in humans. Nature. 2005 Oct 13; 437(7061):1032-7. PMID: 16136080.
      View in: PubMed
    27. Ficenec D, Osborne M, Pradines J, Richards D, Felciano R, Cho R, Chen RO, Liefeld T, Owen J, Ruttenberg A, Reich C, Horvath J, Clark T. Computational knowledge integration in biopharmaceutical research. Brief Bioinform. 2003 Sep; 4(3):260-78. PMID: 14582520.
      View in: PubMed
    28. Cho R, Campbell MJ. Transcription, genomes, function. Trends Genet. 2000 Sep; 16(9):409-15. PMID: 10973070.
      View in: PubMed
    29. Cho R. Deriving meaning from genomic information. Biotechnol Genet Eng Rev. 2000; 17:91-107. PMID: 11255683.
      View in: PubMed
    30. Cho R, Mindrinos M, Richards DR, Sapolsky RJ, Anderson M, Drenkard E, Dewdney J, Reuber TL, Stammers M, Federspiel N, Theologis A, Yang WH, Hubbell E, Au M, Chung EY, Lashkari D, Lemieux B, Dean C, Lipshutz RJ, Ausubel FM, Davis RW, Oefner PJ. Genome-wide mapping with biallelic markers in Arabidopsis thaliana. Nat Genet. 1999 Oct; 23(2):203-7. PMID: 10508518.
      View in: PubMed
    31. Wolfsberg TG, Gabrielian AE, Campbell MJ, Cho R, Spouge JL, Landsman D. Candidate regulatory sequence elements for cell cycle-dependent transcription in Saccharomyces cerevisiae. Genome Res. 1999 Aug; 9(8):775-92. PMID: 10447512; PMCID: PMC310804.
    32. Tavazoie S, Hughes JD, Campbell MJ, Cho R, Church GM. Systematic determination of genetic network architecture. Nat Genet. 1999 Jul; 22(3):281-5. PMID: 10391217.
      View in: PubMed
    33. Cho R, Campbell MJ, Winzeler EA, Steinmetz L, Conway A, Wodicka L, Wolfsberg TG, Gabrielian AE, Landsman D, Lockhart DJ, Davis RW. A genome-wide transcriptional analysis of the mitotic cell cycle. Mol Cell. 1998 Jul; 2(1):65-73. PMID: 9702192.
      View in: PubMed
    34. Cho R, Fromont-Racine M, Wodicka L, Feierbach B, Stearns T, Legrain P, Lockhart DJ, Davis RW. Parallel analysis of genetic selections using whole genome oligonucleotide arrays. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3752-7. PMID: 9520439; PMCID: PMC19909.