Marlys Fassett, MD, PhD

Title(s)Associate Professor, Dermatology
SchoolSchool of Medicine
Address35 Medical Center Way, #1026
San Francisco CA 94143
Phone415-353-7800
PronounsShe/Her/Hers
ORCID ORCID Icon0000-0002-5750-1928 Additional info
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    Collapse Biography 
    Collapse Education and Training
    HARVARD COLLEGE, CambridgeAB mcl2001Biochemistry
    HARVARD MEDICAL SCHOOL, BostonPHD2009Immunology
    HARVARD MEDICAL SCHOOL, HST, BostonMD2011Medical Scientist Training Program (MSTP)
    BIDMC/HARVARD MEDICAL SCHOOL, BostonInternship2012Internal Medicine
    UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, San FranciscoResidency2015Dermatology
    UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, San Francisco2019DEI Training

    Collapse Overview 
    Collapse Overview
    Please call UCSF Dermatology at 415 353 7800 for clinical care inquiries or appointments. The telephone number listed here is not monitored.

    Collapse Research 
    Collapse Research Activities and Funding
    Illuminating IL-31-producing cells in allergic skin disease
    NIH/NIAMS R03AR082948Jul 15, 2023 - Jun 30, 2025
    Role: Principal Investigator
    Interleukin-31 at the neuroimmune interface of pruritus and dermatitis
    NIH K08AR074556Sep 25, 2019 - Aug 31, 2024
    Role: Principal Investigator
    Junior Faculty Pilot Award
    UCSF PREMIER/MT ZION HEALTH FUND Jul 1, 2018 - Jun 30, 2019
    Physician-Scientist Career Development Award
    DERMATOLOGY FOUNDATION Jul 1, 2017 - Sep 30, 2019
    DERMATOLOGIST INVESTIGATOR RESEARCH FELLOWSHIP
    DERMATOLOGY FOUNDATION Jul 1, 2015 - Jul 1, 2016
    NIH/NIAMS T32AR007175Jul 1, 2014 - Jul 1, 2016
    Nur77 family transcription factors in T1DM immune tolerance and Treg differentiation
    NIH/NIDDK T32DK007260Sep 1, 2006 - Jul 31, 2008

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patient photographs taken without instructions are of sufficient quality for clinical decision-making in teledermatology. Dermatol Online J. 2024 Jun 15; 30(3). Liu JY, Lohman ME, Klufas D, Fassett M, Amerson E, Twigg A, Leslie K, Khodosh R. PMID: 39090050.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Neuropeptide substance P alters stem cell fate to aid wound healing and promote epidermal stratification through asymmetric stem cell divisions. Stem Cells. 2024 Feb 01. Khalifa A, Xiao T, Abegaze B, Weisenberger T, Charruyer A, Sanad S, AbuElnasr T, Kashem SW, Fassett M, Ghadially R. PMID: 38301639.
      View in: PubMed   Mentions:    Fields:    
    3. An essential role for miR-15/16 in Treg suppression and restriction of proliferation. Cell Rep. 2023 10 31; 42(10):113298. Johansson K, Gagnon JD, Zhou SK, Fassett MS, Schroeder AW, Kageyama R, Bautista RA, Pham H, Woodruff PG, Ansel KM. PMID: 37862171; PMCID: PMC10664750.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    4. IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis. Sci Immunol. 2023 10 20; 8(88):eabi6887. Fassett MS, Braz JM, Castellanos CA, Salvatierra JJ, Sadeghi M, Yu X, Schroeder AW, Caston J, Munoz-Sandoval P, Roy S, Lazarevsky S, Mar DJ, Zhou CJ, Shin JS, Basbaum AI, Ansel KM. PMID: 37831760; PMCID: PMC10890830.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    5. Can Serum Biomarkers for Prurigo Nodularis Expose Pathophysiology or Just Treatment Response? JAMA Dermatol. 2023 09 01; 159(9):915-917. Kashem SW, Fassett MS. PMID: 37556170.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Evaluation of Gabapentin and Transforaminal Corticosteroid Injections for Brachioradial Pruritus. JAMA Dermatol. 2022 09 01; 158(9):1070-1071. Gutierrez RA, Berger TG, Shah V, Agnihothri R, Demir-Deviren S, Fassett MS. PMID: 35830176; PMCID: PMC9280609.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Innate type 2 immunity controls hair follicle commensalism by Demodex mites. Immunity. 2022 10 11; 55(10):1891-1908.e12. Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, Singh K, Damsky W, Liao C, Arouge E, Tenvooren I, Marquez DM, Schroeder AW, Cohen JN, Fassett MS, Lee J, Daniel SG, Bittinger K, Díaz RE, Fraser JS, Ali N, Ansel KM, Spitzer MH, Liang HE, Locksley RM. PMID: 36044899; PMCID: PMC9561030.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. Obesity alters pathology and treatment response in inflammatory disease. Nature. 2022 04; 604(7905):337-342. Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Crotty Alexander LE, Suh JM, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee IK, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A. PMID: 35355021; PMCID: PMC9165753.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    9. Incidence and Characteristics of Delayed Injection Site Reaction to the mRNA-1273 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine (Moderna) in a Cohort of Hospital Employees. Clin Infect Dis. 2022 03 01; 74(4):591-596. Jacobson MA, Zakaria A, Maung Z, Hart C, McCalmont TH, Fassett M, Amerson E. PMID: 34086881; PMCID: PMC8244618.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Varicella-zoster and herpes simplex virus reactivation post-COVID-19 vaccination: a review of 40 cases in an International Dermatology Registry. J Eur Acad Dermatol Venereol. 2022 Jan; 36(1):e6-e9. Fathy RA, McMahon DE, Lee C, Chamberlin GC, Rosenbach M, Lipoff JB, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Fassett M, Fox LP, Greenberg HL, Blumenthal K, Freeman EE. PMID: 34487581; PMCID: PMC8656951.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCellsPHPublic Health
    11. Cutaneous Pathology of COVID-19 as a Window into Immunologic Mechanisms of Disease. Dermatol Clin. 2021 Oct; 39(4):533-543. Gallman AE, Fassett MS. PMID: 34556243; PMCID: PMC8297957.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Cold and COVID: recurrent pernio during the COVID-19 pandemic. Br J Dermatol. 2021 07; 185(1):214-216. Freeman EE, McMahon DE, Lipoff JB, Rosenbach M, Desai SR, Fassett M, French LE, Lim HW, Hruza GJ, Fox LP. PMID: 33657646; PMCID: PMC8014788.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    13. Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). Braz JM, Dembo T, Charruyer A, Ghadially R, Fassett MS, Basbaum AI. PMID: 33602818; PMCID: PMC7923356.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Long COVID in the skin: a registry analysis of COVID-19 dermatological duration. Lancet Infect Dis. 2021 03; 21(3):313-314. McMahon DE, Gallman AE, Hruza GJ, Rosenbach M, Lipoff JB, Desai SR, French LE, Lim H, Cyster JG, Fox LP, Fassett MS, Freeman EE. PMID: 33460566; PMCID: PMC7836995.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    15. Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation. iScience. 2020 Oct 23; 23(10):101582. Liu Y, Cook C, Sedgewick AJ, Zhang S, Fassett MS, Ricardo-Gonzalez RR, Harirchian P, Kashem SW, Hanakawa S, Leistico JR, North JP, Taylor MA, Zhang W, Man MQ, Charruyer A, Beliakova-Bethell N, Benz SC, Ghadially R, Mauro TM, Kaplan DH, Kabashima K, Choi J, Song JS, Cho RJ, Cheng JB. PMID: 33205009; PMCID: PMC7648132.
      View in: PubMed   Mentions: 24  
    16. Timing of PCR and antibody testing in patients with COVID-19-associated dermatologic manifestations. J Am Acad Dermatol. 2021 02; 84(2):505-507. Freeman EE, McMahon DE, Hruza GJ, Lipoff JB, French LE, Fox LP, Fassett MS. PMID: 32920037; PMCID: PMC7482613.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    17. Treatment of PD-1/PD-L1 Inhibitor-Induced Dermatitis Resolves Concomitant Eruptive Keratoacanthomas. JAMA Dermatol. 2020 05 01; 156(5):598-600. Crow LD, Perkins I, Twigg AR, Fassett MS, LeBoit PE, Berger TG, Khodosh R. PMID: 32211828.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Neuroimmune interactions in chronic itch of atopic dermatitis. J Eur Acad Dermatol Venereol. 2020 Feb; 34(2):239-250. Yosipovitch G, Berger T, Fassett MS. PMID: 31566796; PMCID: PMC7027518.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    19. miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. Cell Rep. 2019 08 20; 28(8):2169-2181.e4. Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, McManus MT, Marson A, Matloubian M, Sanjabi S, Ansel KM. PMID: 31433990; PMCID: PMC6715152.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    20. Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution. Cell Rep. 2018 10 23; 25(4):871-883. Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu SS, Gray JW, Purdom E, Paus R, Vaske CJ, Benz SC, Song JS, Cho RJ. PMID: 30355494; PMCID: PMC6367716.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    21. Identification of Functionally Relevant microRNAs in the Regulation of Allergic Inflammation. Methods Mol Biol. 2018; 1799:341-351. Fassett MS, Pua HH, Simpson LJ, Steiner DF, Ansel KM. PMID: 29956162; PMCID: PMC6193755.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    22. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012 Oct; 13(10):972-80. Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. PMID: 22961053; PMCID: PMC3698954.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansAnimalsCells
    23. Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3891-6. Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C. PMID: 22345564; PMCID: PMC3309794.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    24. The Immunological Genome Project: networks of gene expression in immune cells. Nat Immunol. 2008 Oct; 9(10):1091-4. Heng TS, Painter MW, Immunological Genome Project Consortium. PMID: 18800157.
      View in: PubMed   Mentions: 1039     Fields:    
    25. Viral evasion of natural killer cells. Nat Immunol. 2002 Nov; 3(11):1006-12. Orange JS, Fassett MS, Koopman LA, Boyson JE, Strominger JL. PMID: 12407408.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    26. Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clustering. Proc Natl Acad Sci U S A. 2001 Dec 04; 98(25):14547-52. Fassett MS, Davis DM, Valter MM, Cohen GB, Strominger JL. PMID: 11724921; PMCID: PMC64719.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    27. The human natural killer cell immune synapse. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):15062-7. Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL. PMID: 10611338; PMCID: PMC24773.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansCells
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