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A transcriptional switch governs fibroblast activation in heart disease. Nature. 2021 Jul; 595(7867):438-443.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. PMID: 34163071.
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Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. Science. 2021 02 12; 371(6530).
Theodoris CV, Zhou P, Liu L, Zhang Y, Nishino T, Huang Y, Kostina A, Ranade SS, Gifford CA, Uspenskiy V, Malashicheva A, Ding S, Srivastava D. PMID: 33303684.
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8 Fields:
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HumansAnimalsCells
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Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. Nature. 2019 08; 572(7767):120-124.
de Soysa TY, Ranade SS, Okawa S, Ravichandran S, Huang Y, Salunga HT, Schricker A, Del Sol A, Gifford CA, Srivastava D. PMID: 31341279.
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32 Fields:
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Animals
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Oligogenic inheritance of a human heart disease involving a genetic modifier. Science. 2019 05 31; 364(6443):865-870.
Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D. PMID: 31147515.
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32 Fields:
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HumansAnimalsCells
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Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):12817-12822.
Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A. PMID: 30482854.
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32 Fields:
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AnimalsCells
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Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. J Clin Invest. 2017 May 01; 127(5):1683-1688.
Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D. PMID: 28346225.
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14 Fields:
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HumansAnimalsCells
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Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature. 2017 01 12; 541(7636):176-181.
Nonomura K, Woo SH, Chang RB, Gillich A, Qiu Z, Francisco AG, Ranade SS, Liberles SD, Patapoutian A. PMID: 28002412.
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76 Fields:
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AnimalsCells
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Mechanosensory hair cells express two molecularly distinct mechanotransduction channels. Nat Neurosci. 2017 01; 20(1):24-33.
Wu Z, Grillet N, Zhao B, Cunningham C, Harkins-Perry S, Coste B, Ranade S, Zebarjadi N, Beurg M, Fettiplace R, Patapoutian A, Mueller U. PMID: 27893727.
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34 Fields:
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AnimalsCells
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Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling. Cell Rep. 2015 Nov 10; 13(6):1161-1171.
Retailleau K, Duprat F, Arhatte M, Ranade SS, Peyronnet R, Martins JR, Jodar M, Moro C, Offermanns S, Feng Y, Demolombe S, Patel A, Honoré E. PMID: 26526998.
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63 Fields:
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AnimalsCells
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Mechanically Activated Ion Channels. Neuron. 2015 Oct 1; 88(2):433.
Sanjeev S. Ranade, Ruhma Syeda, Ardem Patapoutian. .
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Mechanically Activated Ion Channels. Neuron. 2015 Sep 23; 87(6):1162-1179.
Ranade SS, Syeda R, Patapoutian A. PMID: 26402601.
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131 Fields:
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HumansAnimalsCells
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Piezo1 links mechanical forces to red blood cell volume. Elife. 2015 May 22; 4.
Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A. PMID: 26001274.
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134 Fields:
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AnimalsCells
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Piezo2 is the major transducer of mechanical forces for touch sensation in mice. Nature. 2014 Dec 04; 516(7529):121-5.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. PMID: 25471886.
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185 Fields:
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AnimalsCells
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Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10347-52.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. PMID: 24958852.
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181 Fields:
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AnimalsCells
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Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature. 2014 May 29; 509(7502):617-21.
Maksimovic S, Nakatani M, Baba Y, Nelson AM, Marshall KL, Wellnitz SA, Firozi P, Woo SH, Ranade S, Patapoutian A, Lumpkin EA. PMID: 24717432.
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140 Fields:
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AnimalsCells
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Piezo2 is required for Merkel-cell mechanotransduction. Nature. 2014 May 29; 509(7502):622-6.
Woo SH, Ranade S, Weyer AD, Dubin AE, Baba Y, Qiu Z, Petrus M, Miyamoto T, Reddy K, Lumpkin EA, Stucky CL, Patapoutian A. PMID: 24717433.
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207 Fields:
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AnimalsCells
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Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science. 2010 Oct 01; 330(6000):55-60.
Coste B, Mathur J, Schmidt M, Earley TJ, Ranade S, Petrus MJ, Dubin AE, Patapoutian A. PMID: 20813920.
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579 Fields:
Translation:
AnimalsCells