Scott Thomas, PhD

Title(s)Associate Researcher, Medicine
SchoolSchool of Medicine
Address1450 Third St, #222
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division
    University of California, DavisPhDBiochemistry, Cell, and Molecular Biology

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Phase IB Trial of the PI3K Inhibitor Alpelisib and Weekly Cisplatin in Patients with Solid Tumor Malignancies. Cancer Res Commun. 2022 Jul; 2(7):570-576. Tsang ES, Aggarwal RR, Dhawan MS, Bergsland EK, Alvarez EA, Calabrese S, Pacaud R, Garcia J, Fattah D, Thomas S, Grabowsky J, Moasser MM, Munster PN. PMID: 36923283; PMCID: PMC10010328.
      View in: PubMed   Mentions:
    2. The effect of marrow secretome and culture environment on the rate of metastatic breast cancer cell migration in two and three dimensions. Mol Biol Cell. 2021 05 01; 32(10):1009-1019. Curtis KJ, Mai C, Martin H, Oberman AG, Alderfer L, Romero-Moreno R, Walsh M, Mitros SF, Thomas SG, Dynako JA, Zimmer DI, McNamara LM, Littlepage LE, Niebur GL. PMID: 33689396; PMCID: PMC8101488.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    3. Exhausted T cell signature predicts immunotherapy response in ER-positive breast cancer. Nat Commun. 2020 07 17; 11(1):3584. Terranova-Barberio M, Pawlowska N, Dhawan M, Moasser M, Chien AJ, Melisko ME, Rugo H, Rahimi R, Deal T, Daud A, Rosenblum MD, Thomas S, Munster PN. PMID: 32681091; PMCID: PMC7367885.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCellsCTClinical Trials
    4. Histone Deacetylase Inhibition with Panobinostat Combined with Intensive Induction Chemotherapy in Older Patients with Acute Myeloid Leukemia: Phase I Study Results. Clin Cancer Res. 2019 08 15; 25(16):4917-4923. Wieduwilt MJ, Pawlowska N, Thomas S, Olin R, Logan AC, Damon LE, Martin T, Kang M, Sayre PH, Boyer W, Gaensler KML, Anderson K, Munster PN, Andreadis C. PMID: 31152020.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    5. Local delivery of hormonal therapy with silastic tubing for prevention and treatment of breast cancer. Sci Rep. 2018 01 08; 8(1):92. Park J, Thomas S, Zhong AY, Wolfe AR, Krings G, Terranova-Barberio M, Pawlowska N, Benet LZ, Munster PN. PMID: 29311658; PMCID: PMC5758798.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. HDAC inhibition potentiates immunotherapy in triple negative breast cancer. Oncotarget. 2017 Dec 26; 8(69):114156-114172. Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN. PMID: 29371976; PMCID: PMC5768393.
      View in: PubMed   Mentions: 76     Fields:    
    7. Host histone acetylation unlocks HDAC inhibitor potential. Oncotarget. 2017 Dec 05; 8(63):106161-106162. Terranova-Barberio M, Thomas S, Munster PN. PMID: 29290932; PMCID: PMC5739717.
      View in: PubMed   Mentions: 1     Fields:    
    8. Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors. Breast Cancer Res. 2017 Sep 11; 19(1):107. Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, Aggarwal R, Munster PN, Esserman LJ, Ruan W, Wu AHB, Yee D, Dartois V, Savic RM, Wolf DM, van 't Veer L. PMID: 28893315; PMCID: PMC5594551.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    9. Autologous Fat Grafting as a Novel Antiestrogen Vehicle for the Treatment of Breast Cancer. Plast Reconstr Surg. 2017 Sep; 140(3):537-544. Thomas S, Chen S, Sbitany H, Kwon E, Piper M, Park J, Terranova Barberio M, Pawlowska N, Munster PN. PMID: 28841614; PMCID: PMC5604844.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Differential Toxicity in Patients with and without DNA Repair Mutations: Phase I Study of Carboplatin and Talazoparib in Advanced Solid Tumors. Clin Cancer Res. 2017 Nov 01; 23(21):6400-6410. Dhawan MS, Bartelink IH, Aggarwal RR, Leng J, Zhang JZ, Pawlowska N, Terranova-Barberio M, Grabowsky JA, Gewitz A, Chien AJ, Moasser M, Kelley RK, Maktabi T, Thomas S, Munster PN. PMID: 28790114.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCellsCTClinical Trials
    11. Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies. J Clin Oncol. 2017 Apr 10; 35(11):1231-1239. Aggarwal R, Thomas S, Pawlowska N, Bartelink I, Grabowsky J, Jahan T, Cripps A, Harb A, Leng J, Reinert A, Mastroserio I, Truong TG, Ryan CJ, Munster PN. PMID: 28221861; PMCID: PMC5791833.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCellsCTClinical Trials
    12. Epigenetic modifiers in immunotherapy: a focus on checkpoint inhibitors. Immunotherapy. 2016 06; 8(6):705-19. Terranova-Barberio M, Thomas S, Munster PN. PMID: 27197539; PMCID: PMC5705793.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    13. A phase I trial of panobinostat and epirubicin in solid tumors with a dose expansion in patients with sarcoma. Ann Oncol. 2016 05; 27(5):947-52. Thomas S, Aggarwal R, Jahan T, Ryan C, Troung T, Cripps AM, Raha P, Thurn KT, Chen S, Grabowsky JA, Park J, Hwang J, Daud A, Munster PN. PMID: 26903311; PMCID: PMC4843187.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    14. Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression. Breast Cancer Res. 2015 Feb 25; 17:26. Raha P, Thomas S, Thurn KT, Park J, Munster PN. PMID: 25848915; PMCID: PMC4367983.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    15. Epigenetic modulation with histone deacetylase inhibitors in combination with immunotherapy. Epigenomics. 2015; 7(4):641-52. Park J, Thomas S, Munster PN. PMID: 26111034.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    16. Histone deacetylase regulation of ATM-mediated DNA damage signaling. Mol Cancer Ther. 2013 Oct; 12(10):2078-87. Thurn KT, Thomas S, Raha P, Qureshi I, Munster PN. PMID: 23939379; PMCID: PMC3821775.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    17. Efficacy of histone deacetylase and estrogen receptor inhibition in breast cancer cells due to concerted down regulation of Akt. PLoS One. 2013; 8(7):e68973. Thomas S, Thurn KT, Raha P, Chen S, Munster PN. PMID: 23874830; PMCID: PMC3711340.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    18. Epigenetic modulation: a novel therapeutic target for overcoming hormonal therapy resistance. Epigenomics. 2011 Aug; 3(4):451-70. Raha P, Thomas S, Munster PN. PMID: 22126205.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    19. A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer. Br J Cancer. 2011 Jun 07; 104(12):1828-35. Munster PN, Thurn KT, Thomas S, Raha P, Lacevic M, Miller A, Melisko M, Ismail-Khan R, Rugo H, Moasser M, Minton SE. PMID: 21559012; PMCID: PMC3111195.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansCellsCTClinical Trials
    20. Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy. Breast Cancer Res Treat. 2011 Nov; 130(2):437-47. Thomas S, Thurn KT, Biçaku E, Marchion DC, Münster PN. PMID: 21298336; PMCID: PMC3760725.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    21. Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer. Future Oncol. 2011 Feb; 7(2):263-83. Thurn KT, Thomas S, Moore A, Munster PN. PMID: 21345145; PMCID: PMC3127396.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    22. Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker. Br J Cancer. 2009 Oct 06; 101(7):1044-50. Munster PN, Marchion D, Thomas S, Egorin M, Minton S, Springett G, Lee JH, Simon G, Chiappori A, Sullivan D, Daud A. PMID: 19738609; PMCID: PMC2768109.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCellsCTClinical Trials
    23. Histone deacetylase inhibitor induced modulation of anti-estrogen therapy. Cancer Lett. 2009 Aug 08; 280(2):184-91. Thomas S, Munster PN. PMID: 19185986.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    24. A Bir1p Sli15p kinetochore passenger complex regulates septin organization during anaphase. Mol Biol Cell. 2007 Oct; 18(10):3820-34. Thomas S, Kaplan KB. PMID: 17652458; PMCID: PMC1995702.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    25. A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis. J Cell Biol. 2005 Dec 05; 171(5):773-84. Gillis AN, Thomas S, Hansen SD, Kaplan KB. PMID: 16330709; PMCID: PMC2171293.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    26. Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function. Mol Biol Cell. 2004 Jul; 15(7):3366-78. Rodrigo-Brenni MC, Thomas S, Bouck DC, Kaplan KB. PMID: 15090617; PMCID: PMC452590.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    27. Eukaryotic glycosyltransferases: cysteines and disulfides. Glycobiology. 2002 Feb; 12(2):4G-7G. Thomas S, Yen TY, Macher BA. PMID: 11954545.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    28. Human alpha 1,3/4 fucosyltransferases. Characterization of highly conserved cysteine residues and N-linked glycosylation sites. J Biol Chem. 2000 Aug 11; 275(32):24237-45. Holmes EH, Yen TY, Thomas S, Joshi R, Nguyen A, Long T, Gallet F, Maftah A, Julien R, Macher BA. PMID: 10816554.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    29. A historically controlled trial of tyrosine for cocaine dependence. J Psychoactive Drugs. 1996 Jul-Sep; 28(3):305-9. Galloway GP, Frederick SL, Thomas S, Hayner G, Staggers FE, Wiehl WO, Sajo E, Amodia D, Stewart P. PMID: 8895116.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
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