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Poster 363: Non-Biased Analysis of ACL Tissue Shows Distinct Differences in Cell Type and Gene Expression Between Male and Female Populations. Orthopaedic Journal of Sports Medicine. 2024 Jul 1; 12(7 suppl2):2325967124s00329.
Lau LJ, Garcia GS, Wague WA, Lizarraga LM, Sharma SS, O'Connell OG, Wong WS, Liu LX, Feeley FB. .
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Defining Endogenous Mitochondrial Transfer in Muscle After Rotator Cuff Injury. Am J Sports Med. 2024 02; 52(2):451-460.
Chi HM, Davies MR, Garcia SM, Montenegro C, Sharma S, Lizarraga M, Wang Z, Nuthalapati P, Kim HT, Liu X, Feeley BT. PMID: 38174367.
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Translation:
HumansAnimalsCells
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Algorithmic assessment of shoulder function using smartphone video capture and machine learning. Sci Rep. 2023 11 15; 13(1):19986.
Darevsky DM, Hu DA, Gomez FA, Davies MR, Liu X, Feeley BT. PMID: 37968288; PMCID: PMC10652003.
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Translation:
HumansAnimals
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Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes. Stem Cell Res Ther. 2023 11 07; 14(1):321.
Liu M, Ng M, Phu T, Bouchareychas L, Feeley BT, Kim HT, Raffai RL, Liu X. PMID: 37936229; PMCID: PMC10631219.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A Tool for Low-Cost, Quantitative Assessment of Shoulder Function Using Machine Learning. medRxiv. 2023 Apr 17.
Darevsky DM, Hu DA, Gomez FA, Davies MR, Liu X, Feeley BT. PMID: 37131827; PMCID: PMC10153347.
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The Role of Matrix Metalloproteinase-13 (MMP13) in TGFβ/BMP Pathway Regulation of Fibro-Adipogenic Progenitor (FAP) Differentiation. Cell Physiol Biochem. 2022 Dec 20; 56(6):730-743.
Liu M, Feeley BT, Kim HT, Liu X. PMID: 36537139.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes That Treat Rotator Cuff Muscle Degeneration in Mice and Are Identified in Humans by Single-Cell RNA Sequencing. Am J Sports Med. 2022 07; 50(8):2247-2257.
Davies MR, Garcia S, Liu M, Chi H, Kim HT, Raffai RL, Liu X, Feeley BT. PMID: 35604307.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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A novel mouse model of hindlimb joint contracture with 3D-printed casts. J Orthop Res. 2022 12; 40(12):2865-2872.
Moore LK, Lee CS, Agha O, Liu M, Zhang H, Dang ABC, Dang ABC, Dang A, Liu X, Feeley BT. PMID: 35266583; PMCID: PMC10289010.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Rotator Cuff Tear Size Regulates Fibroadipogenic Progenitor Number and Gene Expression Profile in the Supraspinatus Independent of Patient Age. Am J Sports Med. 2022 01; 50(1):208-215.
Davies MR, Chi H, Kaur G, Liu M, Ma CB, Kim HT, Liu X, Feeley BT. PMID: 34779676; PMCID: PMC9280916.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Does the Antimalarial Drug Quinine Contribute to Muscle Fibro/Adipogenic Progenitor Fibrogenesis?. Muscles Ligaments and Tendons Journal. 2021 Nov 1; 11(04):635.
Jay JJ, Liu LM, Liu LX, Feeley FB, Sabatini SC. .
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Microenergy acoustic pulses promotes muscle regeneration through in situ activation of muscle stem cells. J Orthop Res. 2022 07; 40(7):1621-1631.
Zhang H, Kim HT, Feeley BT, Lin G, Lue TF, Liu M, Banie L, Liu X. PMID: 34657315; PMCID: PMC9013392.
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Translation:
AnimalsCells
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The Role of Fibro-Adipogenic Progenitors in Musculoskeletal Disease. Muscles Ligaments and Tendons Journal. 2021 May 1; 11(02):201.
Kaur KG, Davies DM, Liu LX, Delioglu DB. .
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Paraspinal muscle degeneration and regenerative potential in a Murine model of Lumbar Disc Injury. N Am Spine Soc J. 2021 Jun; 6:100061.
Davies MR, Kaur G, Liu X, Alvarado FG, Nuthalapati P, Liu M, Diaz A, Lotz JC, Bailey JF, Feeley BT. PMID: 35141626; PMCID: PMC8820077.
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PubMed Mentions:
3
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Preconditioning improves muscle regeneration after ischemia-reperfusion injury. J Orthop Res. 2021 09; 39(9):1889-1897.
Zhang H, Liu M, Kim HT, Feeley BT, Liu X. PMID: 33232533; PMCID: PMC9257970.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Brown Beige Fat Activation after Skeletal Muscle Ischemia-Reperfusion Injury. Muscles Ligaments and Tendons Journal. 2020 Nov 1; 10(04):579.
Liu LM, Wang WZ, Lee LC, Nguyen NC, Lee LL, Kim KH, Feeley FB, Liu LX. .
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Trichostatin A regulates fibro/adipogenic progenitor adipogenesis epigenetically and reduces rotator cuff muscle fatty infiltration. J Orthop Res. 2021 07; 39(7):1452-1462.
Liu X, Liu M, Lee L, Davies M, Wang Z, Kim H, Feeley BT. PMID: 32970360; PMCID: PMC7987912.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Human Rotator Cuff Tears Have an Endogenous, Inducible Stem Cell Source Capable of Improving Muscle Quality and Function After Rotator Cuff Repair. Am J Sports Med. 2020 09; 48(11):2660-2668.
Feeley BT, Liu M, Ma CB, Agha O, Aung M, Lee C, Liu X. PMID: 32730704; PMCID: PMC9262007.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Rotator cuff tear degeneration and the role of fibro-adipogenic progenitors. Ann N Y Acad Sci. 2021 04; 1490(1):13-28.
Agha O, Diaz A, Davies M, Kim HT, Liu X, Feeley BT. PMID: 32725671; PMCID: PMC7855559.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Dried plum mitigates spinal cord injury-induced bone loss in mice. JOR Spine. 2020 Jul 15.
Liu LX, Liu LM, Turner TR, Iwaniec IU, Kim KH, Halloran HB. .
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β3-Adrenergic receptor agonist treats rotator cuff fatty infiltration by activating beige fat in mice. J Shoulder Elbow Surg. 2021 Feb; 30(2):373-386.
Wang Z, Liu X, Liu M, Jiang K, Kajimura S, Kim H, Feeley BT. PMID: 32599287; PMCID: PMC7765745.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations. JOR Spine. 2020 Jun; 3(2):e1091.
Agha O, Mueller-Immergluck A, Liu M, Zhang H, Theologis AA, Clark A, Kim HT, Liu X, Feeley BT, Bailey JF. PMID: 32613166; PMCID: PMC7323461.
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PubMed Mentions:
10
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Intramuscular Brown Fat Activation Decreases Muscle Atrophy and Fatty Infiltration and Improves Gait After Delayed Rotator Cuff Repair in Mice. Am J Sports Med. 2020 06; 48(7):1590-1600.
Wang Z, Liu X, Jiang K, Kim H, Kajimura S, Feeley BT. PMID: 32282238.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Beige Fibro-Adipogenic Progenitors Reduce Muscle Degeneration in a Mouse Model of Delayed Repair for Massive Rotator Cuff Tears. Journal of Shoulder and Elbow Surgery. 2020 Apr 1; 29(4):e153-e155.
Lee LC, Liu LM, Agha AO, Kim KH, Liu LX, Feeley FB. .
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Beige FAPs Transplantation Improves Muscle Quality and Shoulder Function After Massive Rotator Cuff Tears. J Orthop Res. 2020 05; 38(5):1159-1166.
Lee C, Liu M, Agha O, Kim HT, Feeley BT, Liu X. PMID: 31808573; PMCID: PMC7162719.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Rotator Cuff Fibro-Adipogenic Progenitors Demonstrate Highest Concentration, Proliferative Capacity, and Adipogenic Potential Across Muscle Groups. J Orthop Res. 2020 05; 38(5):1113-1121.
Lee C, Agha O, Liu M, Davies M, Bertoy L, Kim HT, Liu X, Feeley BT. PMID: 31799698; PMCID: PMC9262119.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Beige fibro-adipogenic progenitor transplantation reduces muscle degeneration and improves function in a mouse model of delayed repair of rotator cuff tears. J Shoulder Elbow Surg. 2020 Apr; 29(4):719-727.
Lee C, Liu M, Agha O, Kim HT, Liu X, Feeley BT. PMID: 31784382; PMCID: PMC7085983.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 05(02):113.
Liu LX, Joshi JS, Ravishankar RB, Laron LD, Kim KH, Feeley FB. .
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Investigating the cellular origin of rotator cuff muscle fatty infiltration and fibrosis after injury. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 06(01):6.
Liu LX, Ning NA, Chen Chang CN, Kim KH, Nissenson NR, Wang WL, Feeley FB. .
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Muscle atrophy and fatty infiltration after an acute rotator cuff repair in a sheep model. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 05(02):106.
Luan LT, Liu LX, Easley EJ, Ravishankar RB, Puttlitz PC, Feeley FB. .
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Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 07(02):202.
Liu LX, Ravishankar RB, Ning NA, Liu LM, Kim KH, Feeley FB. .
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A Mouse Model of Delayed Rotator Cuff Repair Results in Persistent Muscle Atrophy and Fatty Infiltration. Am J Sports Med. 2018 10; 46(12):2981-2989.
Wang Z, Liu X, Davies MR, Horne D, Kim H, Feeley BT. PMID: 30198747; PMCID: PMC6730552.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Reversal of Fatty Infiltration After Suprascapular Nerve Compression Release Is Dependent on UCP1 Expression in Mice. Clin Orthop Relat Res. 2018 08; 476(8):1665-1679.
Wang Z, Feeley BT, Kim HT, Liu X. PMID: 30020151; PMCID: PMC6259770.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Muscle stem cell activation in a mouse model of rotator cuff injury. J Orthop Res. 2018 05; 36(5):1370-1376.
Davies MR, Garcia S, Tamaki S, Liu X, Lee S, Jose A, Pomerantz JH, Feeley BT. PMID: 28786534; PMCID: PMC5803476.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration. Muscles Ligaments Tendons J. 2017 Apr-Jun; 7(2):202-207.
Liu X, Ravishankar B, Ning A, Liu M, Kim HT, Feeley BT. PMID: 29264329; PMCID: PMC5725167.
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PubMed Mentions:
5
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Role of pulsed electromagnetic fields (PEMF) on tenocytes and myoblasts-potential application for treating rotator cuff tears. J Orthop Res. 2017 05; 35(5):956-964.
Liu M, Lee C, Laron D, Zhang N, Waldorff EI, Ryaby JT, Feeley B, Liu X. PMID: 27138553.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Direct Measurement of Tissue Oxygenation as a Method of Diagnosis of Acute Compartment Syndrome. J Orthop Trauma. 2016 Nov; 30(11):585-591.
Weick JW, Kang H, Lee L, Kuether J, Liu X, Hansen EN, Kandemir U, Rollins MD, Mok JM. PMID: 27392158.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Lysophosphatidic acid-induced RhoA signaling and prolonged macrophage infiltration worsens fibrosis and fatty infiltration following rotator cuff tears. J Orthop Res. 2017 07; 35(7):1539-1547.
Davies MR, Lee L, Feeley BT, Kim HT, Liu X. PMID: 27505847; PMCID: PMC5502767.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Investigating the cellular origin of rotator cuff muscle fatty infiltration and fibrosis after injury. Muscles Ligaments Tendons J. 2016 Jan-Mar; 6(1):6-15.
Liu X, Ning AY, Chang NC, Kim H, Nissenson R, Wang L, Feeley BT. PMID: 27331027; PMCID: PMC4915463.
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PubMed Mentions:
45
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TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis. PLoS One. 2016; 11(5):e0155486.
Davies MR, Liu X, Lee L, Laron D, Ning AY, Kim HT, Feeley BT. PMID: 27186977; PMCID: PMC4871364.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Muscle atrophy and fatty infiltration after an acute rotator cuff repair in a sheep model. Muscles Ligaments Tendons J. 2015 Apr-Jun; 5(2):106-12.
Luan T, Liu X, Easley JT, Ravishankar B, Puttlitz C, Feeley BT. PMID: 26261789; PMCID: PMC4496009.
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PubMed Mentions:
17
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Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration. Muscles Ligaments Tendons J. 2015 Apr-Jun; 5(2):113-9.
Liu X, Joshi S, Ravishankar B, Laron D, Kim HT, Feeley BT. PMID: 26261790; PMCID: PMC4496010.
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PubMed Mentions:
6
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Effects of blockade of endogenous Gi signaling in Tie2-expressing cells on bone formation in a mouse model of heterotopic ossification. J Orthop Res. 2015 Aug; 33(8):1212-7.
Wang L, Carroll DO, Liu X, Roth T, Kim H, Halloran B, Nissenson RA. PMID: 25773760.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Rat rotator cuff muscle responds differently from hindlimb muscle to a combined tendon-nerve injury. J Orthop Res. 2015 Jul; 33(7):1046-53.
Davies MR, Ravishankar B, Laron D, Kim HT, Liu X, Feeley BT. PMID: 25974842.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Upregulation of transforming growth factor-β signaling in a rat model of rotator cuff tears. J Shoulder Elbow Surg. 2014 Nov; 23(11):1709-16.
Liu X, Joshi SK, Ravishankar B, Laron D, Kim HT, Feeley BT. PMID: 24875732; PMCID: PMC4198422.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Novel mouse model of spinal cord injury-induced heterotopic ossification. J Rehabil Res Dev. 2014; 51(7):1109-18.
Kang H, Dang AB, Joshi SK, Halloran B, Nissenson R, Zhang X, Li J, Kim HT, Liu X. PMID: 25436890.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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A novel mouse model of trauma induced heterotopic ossification. J Orthop Res. 2014 Feb; 32(2):183-8.
Liu X, Kang H, Shahnazari M, Kim H, Wang L, Larm O, Adolfsson L, Nissenson R, Halloran B. PMID: 24136593.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Differential ubiquitin-proteasome and autophagy signaling following rotator cuff tears and suprascapular nerve injury. J Orthop Res. 2014 Jan; 32(1):138-44.
Joshi SK, Kim HT, Feeley BT, Liu X. PMID: 24018537; PMCID: PMC3856942.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Original article Muscle extracellular matrix degradation and contractibility following tendon rupture and disuse. Muscles Ligaments Tendons J. 2013 Jan; 3(1):35-41.
Zhang Q, Joshi SK, Manzano G, Lovett DH, Kim HT, Liu X. PMID: 23885343; PMCID: PMC3676162.
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PubMed Mentions:
9
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Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy. J Shoulder Elbow Surg. 2013 Dec; 22(12):1702-9.
Kramer EJ, Bodendorfer BM, Laron D, Wong J, Kim HT, Liu X, Feeley BT. PMID: 23664745; PMCID: PMC3806888.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats. J Orthop Res. 2013 May; 31(5):724-30.
Joshi SK, Liu X, Samagh SP, Lovett DH, Bodine SC, Kim HT, Feeley BT. PMID: 23239524; PMCID: PMC4393845.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears. J Orthop Res. 2013 Mar; 31(3):421-6.
Samagh SP, Kramer EJ, Melkus G, Laron D, Bodendorfer BM, Natsuhara K, Kim HT, Liu X, Feeley BT. PMID: 22991068.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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A comparison of lidocaine, ropivacaine and dexamethasone toxicity on bovine tenocytes in culture. J Bone Joint Surg Br. 2012 Jun; 94(6):856-62.
Piper SL, Laron D, Manzano G, Pattnaik T, Liu X, Kim HT, Feeley BT. PMID: 22628605.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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A mouse model of massive rotator cuff tears. J Bone Joint Surg Am. 2012 Apr 04; 94(7):e41.
Liu X, Laron D, Natsuhara K, Manzano G, Kim HT, Feeley BT. PMID: 22488625.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimals
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Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model. J Orthop Res. 2012 Sep; 30(9):1440-6.
Liu X, Joshi SK, Samagh SP, Dang YX, Laron D, Lovett DH, Bodine SC, Kim HT, Feeley BT. PMID: 22378614.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Muscle degeneration in rotator cuff tears. J Shoulder Elbow Surg. 2012 Feb; 21(2):164-74.
Laron D, Samagh SP, Liu X, Kim HT, Feeley BT. PMID: 22244059.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Emerging ideas: matrix metalloproteinase-2 in muscle atrophy. Clin Orthop Relat Res. 2011 Jun; 469(6):1797-9.
Liu X. PMID: 21132408; PMCID: PMC3094615.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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A rat model of massive rotator cuff tears. J Orthop Res. 2011 Apr; 29(4):588-95.
Liu X, Manzano G, Kim HT, Feeley BT. PMID: 20949443.
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PubMed Mentions:
66 Fields:
Translation:
Animals
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Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy. Biochem Biophys Res Commun. 2010 May 28; 396(2):219-23.
Liu X, Manzano G, Lovett DH, Kim HT. PMID: 20398633.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Role of gelatinases in disuse-induced skeletal muscle atrophy. Muscle Nerve. 2010 Feb; 41(2):174-8.
Liu X, Lee DJ, Skittone LK, Natsuhara K, Kim HT. PMID: 19790245.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Pathological changes of human ligament after complete mechanical unloading. Am J Phys Med Rehabil. 2007 Apr; 86(4):282-9.
Chen CH, Liu X, Yeh ML, Huang MH, Zhai Q, Lowe WR, Lintner DM, Luo ZP. PMID: 17303960.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Mechanical strain promotes fibroblast gene expression in presence of corticosteroid. Connect Tissue Res. 2007; 48(2):65-9.
Chen CH, Marymont JV, Huang MH, Geyer M, Luo ZP, Liu X. PMID: 17453907.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Force-mediated dissociation of proteoglycan aggregate in articular cartilage. Biorheology. 2006; 43(3,4):183-90.
Liu X, Sun JQ, Heggeness MH, Yeh ML, Luo ZP. PMID: 16912392.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Strain-related collagen gene expression in human osteoblast-like cells. Cell Tissue Res. 2005 Nov; 322(2):331-4.
Liu X, Zhang X, Luo ZP. PMID: 16133149.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Direct measurement of the rupture force of single pair of decorin interactions. Biochem Biophys Res Commun. 2005 Dec 23; 338(3):1342-5.
Liu X, Yeh ML, Lewis JL, Luo ZP. PMID: 16263082.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Combined effects of estrogen and mechanical loading on anterior cruciate ligament fibroblast biosynthesis. ScientificWorldJournal. 2005 Jan 14; 5:5-8.
Liu X, Luo ZP. PMID: 15674443; PMCID: PMC5936499.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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A modified cell culture method for autologous chondrocyte transplantation. Connect Tissue Res. 2005; 46(2):93-9.
Lee CY, Liu X, Hsu HC, Wang DY, Luo ZP. PMID: 16019419.
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Translation:
AnimalsCells
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The combined regulation of estrogen and cyclic tension on fibroblast biosynthesis derived from anterior cruciate ligament. Matrix Biol. 2004 Aug; 23(5):323-9.
Lee CY, Liu X, Smith CL, Zhang X, Hsu HC, Wang DY, Luo ZP. PMID: 15464364.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Direct quantification of the rupture force of single hyaluronan/hyaluronan binding protein bonds. FEBS Lett. 2004 Apr 09; 563(1-3):23-7.
Liu X, Sun JQ, Heggeness MH, Yeh ML, Luo ZP. PMID: 15063717.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Direct measurements of the compressive properties of single proteoglycan aggregates. Biochem Biophys Res Commun. 2004 Apr 02; 316(2):313-6.
Liu X, Noble PC, Luo ZP. PMID: 15020219.
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PubMed Mentions:
3 Fields:
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A method for testing compressive properties of single proteoglycan aggregates. Biochem Biophys Res Commun. 2003 Jul 25; 307(2):338-41.
Liu X, Noble PC, Luo ZP. PMID: 12859961.
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PubMed Mentions:
2 Fields: