Johannes Kratz, MD
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Title(s) | Assistant Professor, Surgery |
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School | School of Medicine |
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Address | 2340 Sutter Street San Francisco CA 94115
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Phone | 415-353-7502 |
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ORCID
.gif) | 0000-0003-0696-4073  |
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vCard | Download vCard |
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Biography Stanford University, Palo Alto, CA | B.A. (with Distinction) | 1999 | Philosophy | Stanford University, Palo Alto, CA | B.S. (with Honors with Distinction) | 1999 | Biological Sciences | Stanford University, Palo Alto, CA | M.A. | 2000 | Philosophy | Harvard Medical School, Boston, MA | M.D. (Magna Cum Laude) | 2006 | | Massachusetts General Hospital, Boston, MA | Residency | 2014 | General Surgery | University of California, San Francisco, CA | Fellowship | 2017 | Cardiothoracic Surgery | University of California, San Francisco, CA | | 2019 | Diversity, Equity, and Inclusion Champion Training |
American Association for Thoracic Surgery | 2019 | | Michael DeBakey Research Scholarship | University of California, San Francisco | 2019 | | Haile T. Debas Academy of Medical Educators Excellence in Teaching Award | Bakar ImmunoX Initiative | 2019 | | Hellman Family Clinical-Translational Research Development Award | University of California, San Francisco | 2018 | | Van Auken Endowed Chair in Thoracic Oncology | University of California, San Francisco | 2017 | | UCSF Health Exceptional Physician Award | Partners HealthCare | 2012 | | Partners HealthCare Resident/Fellow as Teacher Award | Harvard Medical School | 2012 | | First Place, Oral Presentation, Harvard Medical School Surgery Research Conference | International Association for the Study of Lung Cancer | 2011 | | President's Conference Selection, World Conference on Lung Cancer | Massachusetts General Hospital | 2010 | | Willard M. Daggett Award | Massachusetts General Hospital | 2008 | | Wyeth Scholarship of the American College of Surgeons for the Study of Inflammation | Harvard Medical School | 2006 | | John E. Thayer Scholarship Award | Harvard Medical School | 2006 | | Aesculapian Club | Harvard Medical School | 2005 | | Soma Weiss Scholar Award | Harvard Medical School | 2004 | | Howard Hughes Research Training Fellowship |
Overview Johannes R. Kratz, M.D. is Director of Minimally Invasive and Robotic Thoracic Surgery and holds the Van Auken Endowed Chair in Thoracic Oncology. Kratz graduated magna cum laude from Harvard Medical School and holds a Masters in Philosophy from Stanford.
Kratz worked as research fellow in the Thoracic Oncology Lab from 2008-2011 where he played a pivotal role in the development of a prognostic assay for early-stage lung cancer patients. The novel assay was validated in an international clinical trial led by thoracic surgeons David M. Jablons, M.D. and Michael Mann, M.D. The assay better predicted risk of death in early-stage lung cancer patients versus conventional staging guidelines and later successfully identified Stage 1A lung cancer patients who had a very high likelihood of mortality after surgery. Kratz finished his clinical training as a clinical fellow in Thoracic Surgery at UCSF from 2014 - 2017.
Kratz has published numerous papers and has been the recipient of numerous awards and honors including the Partners Healthcare Resident/Fellow as Teacher Award, Willard M. Daggett Award, Edward Churchill Surgical Research Fellowship, Wyeth Scholarship of the American College of Surgeons, John E. Thayer Scholarship Award, Howard Hughes Medical Fellows Program Continued Support Award, Howard Hughes Medical Student Research Fellowship, and designation as a Soma Weiss Scholar.
Research ORNG Applications Bibliographic
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Resectability, Recurrence, and Risk Stratification of Giant Solitary Fibrous Tumors in the Thoracic Cavity. Ann Surg Oncol. 2021 Mar 16.
Woodard GA, Fels Elliott DR, Yap A, Haro GJ, Kratz JR, Mann MJ, Jones KD, Jablons DM. PMID: 33728541.
View in: PubMed Mentions: Fields:
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Bioinformatic Approaches to Validation and Functional Analysis of 3D Lung Cancer Models. Cancers (Basel). 2021 Feb 09; 13(4).
Li PJ, Roose JP, Jablons DM, Kratz JR. PMID: 33572297.
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Commentary: Cardiothoracic surgery training: Global challenges without universal solutions. J Thorac Cardiovasc Surg. 2021 Jan 20.
Kratz JR, Nguyen TC. PMID: 33622555.
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MO01.13 Molecular Risk Stratification is Independent of EGFR Mutation Status in Identifying Early Stage Non-Squamous Non-Small Cell Lung Cancer Patients at Risk for Recurrence and Likely to Benefit from Adjuvant Chemotherapy. Journal of Thoracic Oncology. 2021 Jan 1; 16(1):s21.
G. Woodard, J. Kratz, G. Haro, M. Gubens, C. Blakely, K. Jones, M. Mann, D. Jablons. .
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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. J Clin Oncol. 2021 01 01; 39(1):66-78.
Glasbey JC, Nepogodiev D, Simoes JFF, Omar O, Li E, Venn ML, Pgdme , Abou Chaar MK, Capizzi V, Chaudhry D, Desai A, Edwards JG, Evans JP, Fiore M, Videria JF, Ford SJ, Ganly I, Griffiths EA, Gujjuri RR, Kolias AG, Kaafarani HMA, Minaya-Bravo A, McKay SC, Mohan HM, Roberts KJ, San Miguel-Méndez C, Pockney P, Shaw R, Smart NJ, Stewart GD, Sundar Mrcog S, Vidya R, Bhangu AA, . PMID: 33021869.
View in: PubMed Mentions: 1 Fields:
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Delaying surgery for patients with a previous SARS-CoV-2 infection. Br J Surg. 2020 Nov; 107(12):e601-e602.
COVIDSurg Collaborative . PMID: 32974904.
View in: PubMed Mentions: 1 Fields: Translation: HumansPHPublic Health
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Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. Cell. 2020 Sep 03; 182(5):1232-1251.e22.
Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA, Naeger DM, Bandyopadhyay S, Shah K, Cech L, Thomas NJ, Gupta A, Gonzalez M, Do H, Tan L, Bacaltos B, Gomez-Sjoberg R, Gubens M, Jahan T, Kratz JR, Jablons D, Neff N, Doebele RC, Weissman J, Blakely CM, Darmanis S, Bivona TG. PMID: 32822576.
View in: PubMed Mentions: 3 Fields:
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Pulmonary Embolus of Benign Liver Tissue Following Partial Hepatectomy. AJSP Review and Reports. 2020 Jul 1; 25(4):e5-e7.
Calixto-Hope G. Lucas, Johannes R. Kratz, Anatoly Urisman. .
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Perioperative Lung Resection Outcomes After Implementation of a Multidisciplinary, Evidence-based Thoracic ERAS Program. Ann Surg. 2019 Dec 05.
Haro GJ, Sheu B, Marcus SG, Sarin A, Campbell L, Jablons DM, Kratz JR. PMID: 31851005.
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Comparison of Conventional TNM and Novel TNMB Staging Systems for Non-Small Cell Lung Cancer. JAMA Netw Open. 2019 12 02; 2(12):e1917062.
Haro GJ, Sheu B, Cook NR, Woodard GA, Mann MJ, Kratz JR. PMID: 31808928.
View in: PubMed Mentions: Fields: Translation: Humans
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MA06.09 Timing of Driver Mutation Development and the Genetic Evolution of Semi-Solid Lung Nodules into Early NSCLC. Journal of Thoracic Oncology. 2019 Oct 1; 14(10):s271-s272.
G. Woodard, V. Ding, I. Kim, K. Jones, G. Chavez, G. Haro, J. Kratz, M. Mann, J. Rotow, C. Blakely, D. Jablons. .
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Esophagectomy Outcomes after Implementation of an Enhanced Recovery after Surgery Program. Journal of the American College of Surgeons. 2019 Oct 1; 229(4):s277.
Greg J. Haro, Fang Yu Sheu, Stanley J. Rogers, David M. Jablons, Johannes R. Kratz. .
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P1.14-58 A Phase II Study to Evaluate Neoadjuvant Osimertinib for Surgically Resectable, EGFR-Mutant Non-Small Cell Lung Cancer. Journal of Thoracic Oncology. 2019 Oct 1; 14(10):s578.
J. Rotow, A. Urisman, C. Mccoach, T. Jahan, T. Bivona, K. Jones, A. Gupta, H. Do, J. Riess, D. Aisner, R. Doebele, D. Jablons, J. Kratz, C. Blakely. .
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Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma. Cancer Manag Res. 2019; 11:8209-8218.
Jiang L, Tolani B, Yeh CC, Fan Y, Reza JA, Horvai AE, Xia E, Kratz JR, Jablons DM, Mann MJ. PMID: 31686913.
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Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging. J Thorac Oncol. 2019 07; 14(7):1223-1232.
Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ. PMID: 30959120.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Applications of Next-Generation Sequencing in Neoantigen Prediction and Cancer Vaccine Development. Genet Test Mol Biomarkers. 2020 Feb; 24(2):59-66.
Lancaster EM, Jablons D, Kratz JR. PMID: 30907630.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Central Airway Obstruction Due to Tracheal Glomus Tumor. Thorac Cardiovasc Surg Rep. 2018 Jan; 7(1):e43-e45.
Haro GJ, Seeley EJ, Jablons DM, Kratz JR. PMID: 30464882.
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Giant right coronary artery aneurysm presenting as cardiac tamponade. Interact Cardiovasc Thorac Surg. 2018 11 01; 27(5):787-789.
Ramirez JL, Kratz JR, Wieselthaler GM. PMID: 29800339.
View in: PubMed Mentions: Fields: Translation: Humans
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P2.16-12 Expanded Data Confirm Molecular Testing Identifies Lung Adenocarcinoma Patients, Including Stage IA, Who Benefit from Adjuvant Chemotherapy. Journal of Thoracic Oncology. 2018 Oct 1; 13(10):s835.
G. Woodard, S. Wang, J. Kratz, G. Haro, M. Gubens, C. Blakely, T. Jahan, K. Jones, M. Mann, D. Jablons. .
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Propensity Matched Analysis of Perioperative Outcomes in Robotic-Assisted Thoracic Surgery, Video Assisted Thoracic Surgery, and Open Lung Resections. Journal of the American College of Surgeons. 2018 Oct 1; 227(4):s53.
Greg J. Haro, Johannes R. Kratz, David M. Jablons, Michael J. Mann, Jasleen Kukreja. .
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P3.03-24 Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging. Journal of Thoracic Oncology. 2018 Oct 1; 13(10):s919.
G. Haro, J. Kratz, N. Cook, J. He, S. Van Den Eeden, G. Woodard, M. Gubens, T. Jahan, K. Jones, I. Kim, B. He, D. Jablons, M. Mann. .
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Intraoperative identification and treatment of a giant right coronary artery aneurysm. Multimed Man Cardiothorac Surg. 2018 Jul 24; 2018.
Ramirez J, Wieselthaler G, Kratz J. PMID: 30070779.
View in: PubMed Mentions: Fields: Translation: Humans
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Surgical Management of Pulmonary Mucormycosis in Third-Trimester Pregnancy. Thorac Cardiovasc Surg Rep. 2018 Jan; 7(1):e27-e29.
Ramirez JL, Urisman A, Kukreja J, Kratz JR. PMID: 29977735.
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Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2018 01; 19(1):58-64.
Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM. PMID: 28645632.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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Management of Lung Cancer Invading the Superior Sulcus. Thorac Surg Clin. 2017 May; 27(2):149-157.
Kratz JR, Woodard G, Jablons DM. PMID: 28363369.
View in: PubMed Mentions: Fields: Translation: Humans
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P1.03-066 Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer TNM Staging Topic: Staging. Journal of Thoracic Oncology. 2017 Jan 1; 12(1):s584-s585.
Johannes Kratz, Nancy Cook, Gavitt Woodard, Kirk Jones, Matthew Gubens, Thierry Jahan, Il-Jin Kim, Biao He, David Jablons, Michael Mann. .
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OA19.06 Adjuvant Chemotherapy Decisions Based on Molecular Risk Status Improves Outcomes in Early Stage, Non-Small Cell Lung Cancer. Journal of Thoracic Oncology. 2017 Jan 1; 12(1):s320.
Gavitt Woodard, Jane Crockard, Clara Zoon-Besselink, Johannes Kratz, Matthew Gubens, Thierry Jahan, Collin Blakely, Kirk Jones, Michael Mann, David Jablons. .
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High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov - Dec; 15(6):888-894.
Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA. PMID: 31208661.
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High risk, high reward: An analysis of outcomes for candidates awaiting hepatic re-transplantation. Ann Hepatol. 2016 Nov-Dec 2016; 15(6):888-894.
Shah JA, Patel MS, Kratz JR, Markmann JF, Vagefi PA. PMID: 27740522.
View in: PubMed Mentions: Fields: Translation: Humans
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Wnt7A is a putative prognostic and chemosensitivity marker in human malignant pleural mesothelioma. Oncol Rep. 2015 Apr; 33(4):2052-60.
Hirata T, Zheng Q, Chen Z, Kinoshita H, Okamoto J, Kratz J, Li H, Lui N, Do H, Cheng T, Tseng HH, Koizumi K, Shimizu K, Zhou HM, Jablons D, He B. PMID: 25632963.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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The race to liver transplantation: a comparison of patients with and without hepatocellular carcinoma from listing to post-transplantation. J Am Coll Surg. 2015 Jun; 220(6):1001-7.
Patel MS, Kohn R, Kratz JR, Shah JA, Markmann JF, Vagefi PA. PMID: 25868408.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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Prognostic and Predictive Biomarker Signatures. Lung Cancer. 2014 May 12; 564-571.
Johannes R. Kratz, David M. Jablons. .
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The migrated liver transplantation candidate: insight into geographic disparities in liver distribution. J Am Coll Surg. 2014 Jun; 218(6):1113-8.
Kohn R, Kratz JR, Markmann JF, Vagefi PA. PMID: 24680570.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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International trial of adjuvant therapy in high risk stage I non-squamous cell carcinoma identified by a 14-gene prognostic signature. Transl Lung Cancer Res. 2013 Jun; 2(3):222-5.
Kratz JR, Mann MJ, Jablons DM. PMID: 25806235.
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Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9.
Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. PMID: 23628816.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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Prognostic assay in small, node-negative non-small cell lung cancer--reply. JAMA. 2013 Feb 27; 309(8):769-70.
Mann MJ, Jablons DM, Kratz JR. PMID: 23443437.
View in: PubMed Mentions: Fields: Translation: Humans
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The role of stem cells in airway repair: implications for the origins of lung cancer. Chin J Cancer. 2013 Feb; 32(2):71-4.
Mulvihill MS, Kratz JR, Pham P, Jablons DM, He B. PMID: 23114089.
View in: PubMed Mentions: 1 Fields: Translation: HumansAnimalsCells
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A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors. JAMA. 2012 Oct 24; 308(16):1629-31.
Kratz JR, Van den Eeden SK, He J, Jablons DM, Mann MJ. PMID: 23093159.
View in: PubMed Mentions: 10 Fields: Translation: Humans
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Development of a rapid and practical mutation screening assay for human lung adenocarcinoma. Int J Oncol. 2012 Jun; 40(6):1900-6.
Choi H, Kratz J, Pham P, Lee S, Ray R, Kwon YW, Mao JH, Kang HC, Jablons D, Kim IJ. PMID: 22407457.
View in: PubMed Mentions: 1 Fields: Translation: HumansCells
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A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet. 2012 Mar 03; 379(9818):823-32.
Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM. PMID: 22285053.
View in: PubMed Mentions: 117 Fields: Translation: Humans
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IL11 is prognostic of survival in lung adenocarcinoma. Journal of the American College of Surgeons. 2011 Sep 1; 213(3):s38-s39.
Johannes R. Kratz, Patrick T. Pham, Michael S. Mulvihill, M. Roshni Ray, Michael J. Mann, David M. Jablons. .
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Child neurology: Brachial plexus birth injury: what every neurologist needs to know. Neurology. 2011 Aug 16; 77(7):695-7.
Pham CB, Kratz JR, Jelin AC, Gelfand AA. PMID: 21844527.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma patients. Clin Lung Cancer. 2011 Jul; 12(4):237-44.
Okamoto J, Kratz JR, Hirata T, Mikami I, Raz D, Segal M, Chen Z, Zhou HM, Pham P, Li H, Yagui-Beltran A, Beltran A, Ray MR, Koizumi K, Shimizu K, Jablons D, He B. PMID: 21726823.
View in: PubMed Mentions: 9 Fields: Translation: HumansCells
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Cancer stem cells in lung tumorigenesis. Ann Thorac Surg. 2010 Jun; 89(6):S2090-5.
Kratz JR, Yagui-Beltrán A, Jablons DM. PMID: 20493987.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
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Genomic prognostic models in early-stage lung cancer. Clin Lung Cancer. 2009 May; 10(3):151-7.
Kratz JR, Jablons DM. PMID: 19443334.
View in: PubMed Mentions: 18 Fields: Translation: Humans
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Anal canal duplication associated with presacral cyst. J Pediatr Surg. 2008 Sep; 43(9):1749-52.
Kratz JR, Deshpande V, Ryan DP, Goldstein AM. PMID: 18779021.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2. J Clin Invest. 2006 Jan; 116(1):49-58.
Parmar KM, Larman HB, Dai G, Zhang Y, Wang ET, Moorthy SN, Kratz JR, Lin Z, Jain MK, Gimbrone MA, García-Cardeña G. PMID: 16341264.
View in: PubMed Mentions: 218 Fields: Translation: HumansCells
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Fluid Mechanical Forces as Extrinsic Modifiers of Endothelial Function. Endothelial Cells in Health and Disease. 2005 Feb 28; 189-202.
Johannes Kratz, Kush Parmar, Sripriya Natarajan, Guillermo García-Cardeña. .
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Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site. J Thorac Cardiovasc Surg. 2004 Oct; 128(4):552-61.
Rabkin-Aikawa E, Aikawa M, Farber M, Kratz JR, Garcia-Cardena G, Kouchoukos NT, Mitchell MB, Jonas RA, Schoen FJ. PMID: 15457156.
View in: PubMed Mentions: 21 Fields: Translation: HumansAnimalsCells
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Catalysis of peptide dissociation from class II MHC-peptide complexes. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):6581-6.
Schmitt L, Kratz JR, Davis MM, McConnell HM. PMID: 10359754.
View in: PubMed Mentions: 8 Fields: Translation: AnimalsCells
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Failure of gloves and other protective devices to prevent transmission of hepatitis B virus to oral surgeons. JAMA. 1988 May 06; 259(17):2558-60.
Reingold AL, Kane MA, Hightower AW. PMID: 3357229.
View in: PubMed Mentions: 6 Fields: Translation: Humans
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Year | Publications |
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1999 | 1 | 2004 | 1 | 2005 | 2 | 2008 | 1 | 2009 | 1 | 2010 | 1 | 2011 | 3 | 2012 | 4 | 2013 | 3 | 2014 | 2 | 2015 | 2 | 2016 | 2 | 2017 | 4 | 2018 | 7 | 2019 | 8 | 2020 | 4 | 2021 | 4 |
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