Lekshmi Santhosh, MD, MA

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue
San Francisco CA 94117
ORCID ORCID Icon0000-0002-9897-3462 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, Berkeley, CAMAEd2019Education
    University of California, San Francisco, CAFellow2018Pulmonary & Critical Care
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    University of California, San Francisco, CAChief Resident2015
    University of California, San Francisco, CA2014Internal Medicine Residency
    Harvard Medical School, Boston, MAMD2011Medicine
    Yale University, New Haven, CTBA2007Psychology/Behavioral Neuroscience
    Collapse Awards and Honors
    UCSF2021Haile T. Debas Academy of Medical Educators Member
    National Academy of Medicine2021NAM Scholar in Diagnostic Excellence
    UCSF Internal Medicine Residency2021Floyd C. Rector Housestaff Teaching Award
    UCSF School of Medicine2021UCSF Excellence in Teaching for Clinical Faculty Award
    American Thoracic Society2021ATS Scholar Top Reviewer Award
    UCSF Department of Obstetrics & Gynecology2020Outstanding Resident Teaching Award
    American Thoracic Society2020Alison Clay Early Career Educator Award
    Association of Pulmonary & Critical Care Medicine Program Directors2020Emerging Educator Award
    UCSF2019Bridges Curriculum - Foundations 1 and 2 Teaching Award - Outstanding Lecture
    CHEST/ACCP2018CHEST/ACCP Early Career Professional Development Scholarship Award
    UCSF2018UCSF School of Medicine Pathways to Discovery 2017-2018 Long-Term Mentor Award
    UCSF2016  - 2017Best Clinical Fellow Award, Division of Pulmonary/Critical Care Medicine (2-time winner)
    Association of Pulmonary & Critical Care Medicine Program Directors2017Research in Medical Education Award
    Western Group on Educational Affairs (WGEA/AAMC)2017Best Oral Research Presentation Award
    UCSF2016UCSF Excellence and Innovation in Graduate Medical Education Award
    UCSF2016Teaching Excellence Award for Cherished House Staff (T.E.A.C.H.) Winner

    Collapse Overview 
    Collapse Overview
    Dr. Lekshmi Santhosh specializes in adult pulmonary and critical care medicine with a focus on medical education. She attends in the Medical ICU, the Neuro ICU, on the Internal Medicine teaching wards, and has clinic at the Pulmonary Outpatient Faculty Practice at UCSF-Parnassus. She is the founder and Medical Director of the multidisciplinary post-COVID/post-ICU OPTIMAL Clinic at UCSF Health.

    She serves as the Associate Program Director for the Pulmonary and Critical Care Medicine Fellowship and the Assistant Site Director for the Internal Medicine Residency at Parnassus. She obtained her Master's in Health Professions Education from UC-Berkeley. She gives clinical lectures to students, residents, fellows, faculty and interprofessional team members. Her primary interests in medical educational research are related to ICU transitions of care, women in leadership development, clinical reasoning, and subspecialty career choice.
    Collapse In The News

    Collapse Research 
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    A Qualitative Analysis of Gender and Racial Disparities in Subspecialty Career Choice
    UCSF Academy of Medical Educators Innovations Grant for Medical EducationJul 1, 2021 - Jul 1, 2022
    Role: Principal Investigator
    Role Description: This grant builds on our prior work quantitating racial/ethnic and gender disparities in the subspecialties to explore the drivers of career choice among medicine residents.
    The Multidisciplinary Post-COVID Post-ICU OPTIMAL Clinic
    Nina Ireland Program in Lung HealthFeb 1, 2021 - Feb 1, 2022
    Role: Lekshmi Santhosh
    Role Description: This grant provides seed funding to support the OPTIMAL Clinic operations.
    Improving ICU-to-Ward Patient Safety Through Design Thinking & Documentation Evaluation
    APCCMPD, CHEST, and ATS Jul 1, 2019 - Jul 1, 2021
    Role: Principal Investigator
    Role Description: This grant builds on our work published in BMJ Quality & Safety looking in-depth at structured communication at the time of the ICU-to-ward transition of care.
    Evaluation of the Expansion of ICU Responsibilities in an Open ICU System and Its Implications on Patient Care & Education
    Nina Ireland Program in Lung Health Jul 1, 2019 - Jul 1, 2021
    Role: Principal Investigator
    Role Description: This project explores the educational and patient care implications of a change in responsibilities between ICU & hospitalist teams.
    Women In Leadership Development (WILD) Series: A Longitudinal GME-Wide Program for Women Trainee Leadership Development
    UCSF Academy of Medical Educators Innovations Grant for Medical EducationJul 1, 2018 - Jul 1, 2019
    Role: Co-Principal Investigator
    Role Description: This grant enables the expansion of our previous 1-day WILD symposium into a longitudinal curriculum for residents and fellows across UCSF GME. Through a mixture of innovative hands-on workshop material, women trainees will obtain concrete leadership skills on a variety of topics, including negotiation, microaggressions, work-life integration, allyship, CV optimization, and more.
    IPASS-ICU: A Structured Communication Framework for ICU Transitions of Care
    UCSF Academy of Medical Educators Innovations Grant for Medical EducationJul 1, 2017 - Jul 1, 2018
    Role: Principal Investigator
    Role Description: In this project, I collaborated with colleagues at Washington University of St. Louis and University of Chicago to further explore the structure, process, and outcomes of ICU-ward transitions of care across multiple sites. We used both quantitative and qualitative methods to further explore this topic.

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. How Has the Pandemic Affected Women in Medicine? A Survey-Based Study on Perceptions of Personal and Career Impacts of COVID-19. Women's Health Reports. 2021; 1(2). . View Publication.
    2. Leadership & Professional Development: How to Teach When You Don’t Know. Journal of Hospital Medicine. 2021 Sep 1; 16(9). Wang WS, Santhosh SL, Wray WC. .
      View in: Publisher Site   Mentions:
    3. Tissue, Teamwork, and Timing: an Exercise in Clinical Reasoning. J Gen Intern Med. 2021 Sep; 36(9):2839-2844. Ahmad TR, Kazberouk A, Santhosh L, Hsu G, Dhaliwal G. PMID: 34244961.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Emphasizing Empathy in Communicating About Uncertainty by Using a Dialogic Approach. Acad Med. 2021 07 01; 96(7):931. Chou CL, Connor DM, Santhosh L. PMID: 34183477.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. If You Build It, Will They Come? The Social Media Footprint of Pulmonary and Critical Care Fellowships. ATS Sch. 2021 Jun; 2(2):149-151. Santhosh L. PMID: 34409405.
      View in: PubMed   Mentions:
    6. A Novel Ambulatory Curriculum for Pulmonary and Critical Care Fellowship Training. ATS Sch. 2021 Jun; 2(2):265-277. Kassutto SM, Santhosh L, Dine CJ, Kreider M, Lapin J, Shah RJ. PMID: 34409420.
      View in: PubMed   Mentions:
    7. An Elusive Seizure. The Neurohospitalist. 2021 May 27; 194187442110180. Han HH, Parks PA, Shah SM, Hsu HG, Santhosh SL. .
      View in: Publisher Site   Mentions:
    8. Longitudinal Milestone Assessment Extending Through Subspecialty Training: The Relationship Between ACGME Internal Medicine Residency Milestones and Subsequent Pulmonary and Critical Care Fellowship Milestones. Acad Med. 2021 May 18. Heath JK, Wang T, Santhosh L, Denson JL, Holmboe E, Yamakazi K, Clay AS, Carlos WG. PMID: 34010863.
      View in: PubMed   Mentions:    Fields:    
    9. Trends in US Internal Medicine Residency and Fellowship Applications During the COVID-19 Pandemic vs Previous Years. JAMA Netw Open. 2021 04 01; 4(4):e218199. Huppert LA, Santhosh L, Babik JM. PMID: 33909057.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    10. Rapid Design and Implementation of Post-COVID-19 Clinics. Chest. 2021 08; 160(2):671-677. Santhosh L, Block B, Kim SY, Raju S, Shah RJ, Thakur N, Brigham EP, Parker AM. PMID: 33811910.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Tips and Traps for Trainees Traversing Social Media. ATS Sch. 2021 Jun; 2(2):185-192. Santhosh L, Carroll CL, Seam N. PMID: 34409413.
      View in: PubMed   Mentions:
    12. Zooming into Focus Groups: Strategies for Qualitative Research in the Era of Social Distancing. ATS Sch. 2021 Jun; 2(2):176-184. Santhosh L, Rojas JC, Lyons PG. PMID: 34409412.
      View in: PubMed   Mentions:
    13. Virtual Interviews at Graduate Medical Education Training Programs: Determining Evidence-Based Best Practices. Acad Med. 2020 Dec 08. Huppert LA, Hsiao EC, Cho KC, Marquez C, Chaudhry RI, Frank J, Goglin SE, Hsu G, Kathpalia P, Khanna R, Kompala T, Rao MN, Bower BA, Trafas V, Santhosh L, Schwartz BS, Babik JM. PMID: 33298691.
      View in: PubMed   Mentions: 5     Fields:    
    14. COVID-19 Infection versus Influenza (Flu) and Other Respiratory Illnesses. Am J Respir Crit Care Med. 2020 11 15; 202(10):P27-P28. Sockrider M, Jamil S, Santhosh L, Carlos WG. PMID: 33021812.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    15. On Treatments and Tests Deferred: Preparing for Collateral Damage from COVID-19. Ann Am Thorac Soc. 2020 11; 17(11):1371-1373. Jain S, Santhosh L. PMID: 32667208.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    16. A call for collaboration and consensus on training for endotracheal intubation in the medical intensive care unit. Crit Care. 2020 10 22; 24(1):621. Brown W, Santhosh L, Brady AK, Denson JL, Niroula A, Pugh ME, Self WH, Joffe AM, O'Neal Maynord P, Carlos WG. PMID: 33092615.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Variation in Intensive Care Unit Intubation Practices in Pulmonary Critical Care Medicine Fellowship. ATS Sch. 2020 Dec; 1(4):395-405. Brady AK, Brown W, Denson JL, Winter G, Niroula A, Santhosh L, Carlos WG. PMID: 33728421.
      View in: PubMed   Mentions:
    18. Strategies for forming effective women's groups. Clin Teach. 2021 Apr; 18(2):126-130. Santhosh L, Harleman E, Venado A, Farrand E, E Gilbreth M, Keenan BP, Thompson VV, Shah RJ. PMID: 33058547.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Patient Safety and Resident Schedules without 24-Hour Shifts. N Engl J Med. 2020 09 24; 383(13):1286-1287. Lyons PG, Rojas JC, Santhosh L. PMID: 32966729.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. During the COVID-19 Pandemic, Lung Specialists of the World Implore You: Inhale Only Clean Air. Am J Respir Crit Care Med. 2020 09 15; 202(6):P19-P20. Santhosh L, Alismail A, Breiburg A, Carlos G, Jamil S. PMID: 32930633.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    21. Family Meetings on Behalf of Patients with Serious Illness. N Engl J Med. 2020 Sep 10; 383(11):e71. Widera E, Anderson WG, Santhosh L, McKee KY, Smith AK, Frank J. PMID: 32905678.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. How do attending physicians describe cognitive overload among their workplace learners? Med Educ. 2020 12; 54(12):1129-1136. Sewell JL, Santhosh L, O'Sullivan PS. PMID: 32628785.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. The "Third Shift": A Path Forward to Recognizing and Funding Gender Equity Efforts. J Womens Health (Larchmt). 2020 11; 29(11):1359-1360. Santhosh L, Keenan BP, Jain S. PMID: 32744885.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Diversity of the Infectious Diseases Trainee Pipeline: The Future Looks Bright, but We Must Not Be Complacent. J Infect Dis. 2020 07 06; 222(3):511-513. Santhosh L, Babik JM. PMID: 31943040.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Hospitalist and Intensivist Experiences of the "Open" Intensive Care Unit Environment: a Qualitative Exploration. J Gen Intern Med. 2020 08; 35(8):2338-2346. Santhosh L, Sewell J. PMID: 32462568.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Diversity in the Pulmonary and Critical Care Medicine Pipeline. Trends in Gender, Race, and Ethnicity among Applicants and Fellows. ATS Sch. 2020 Mar 05; 1(2):152-160. Santhosh L, Babik JM. PMID: 33870279.
      View in: PubMed   Mentions:
    27. Miles to Go Before We Sleep. Reforming the Pulmonary and Critical Care Milestones to Improve Trainee Assessment. ATS Sch. 2020 Feb 21; 1(1):33-43. Heath JK, Dempsey TM, Santhosh L, Edgar L, Fessler HE. PMID: 33870267.
      View in: PubMed   Mentions:
    28. Trends in Racial and Ethnic Diversity in Internal Medicine Subspecialty Fellowships From 2006 to 2018. JAMA Netw Open. 2020 02 05; 3(2):e1920482. Santhosh L, Babik JM. PMID: 32031642.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Leadership Training in Pulmonary and Critical Care: A National Survey of Fellowship Program Directors. Ann Am Thorac Soc. 2020 02; 17(2):243-246. Steinbach TC, Adamson R, Carlos WG, Denson JL, Kritek PA, Santhosh L, Seam N, Wang TS, Çoruh B. PMID: 31661296.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. From Bedrest to Balance. International Journal of Academic Medicine. 2019; 5(3):240-301. Santhosh L. View Publication.
    31. Design and Implementation of a Peer-Reviewed Medical Education Video Competition: The Best of American Thoracic Society Video Lecture Series. J Grad Med Educ. 2019 Oct; 11(5):592-596. Seam N, Richards JB, Kritek PA, Khemasuwan D, McCallister JW, Santhosh L, Prasad B, Bhargava S, Clay AS, Crotty Alexander LE. PMID: 31636831.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. Diagnostic Error and Anchoring Bias in a Patient with Schizophrenia. Am J Med. 2020 03; 133(3):e98-e99. Hemmat S, Santhosh L. PMID: 31520621.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Off Trail, On Track: an Exercise in Clinical Reasoning. J Gen Intern Med. 2019 10; 34(10):2282-2287. Zejnullahu K, Santhosh L, Mourad M, Connor DM. PMID: 31270781.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Diagnostic uncertainty: from education to communication. Diagnosis (Berl). 2019 06 26; 6(2):121-126. Santhosh L, Chou CL, Connor DM. PMID: 30851157.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Strategies to build a clinician-educator career. Clin Teach. 2020 04; 17(2):126-130. Santhosh L, Abdoler E, Babik JM. PMID: 30859740.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. The Complex Problem of Women Trainees in Academic Medicine. J Hosp Med. 2019 03; 14(3):186-188. Keenan B, Santhosh L, Thompson V, Harleman E. PMID: 30811328.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Wildfires Disaster Guidance: Tips for Staying Healthy during Wildfires. Am J Respir Crit Care Med. 2019 01 15; 199(2):P3-P4. Jamil S, Carlos WG, Leard L, Wang A, Santhosh L, Balmes J, Seam N, Dela Cruz CS. PMID: 30644780.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Characterising ICU-ward handoffs at three academic medical centres: process and perceptions. BMJ Qual Saf. 2019 08; 28(8):627-634. Santhosh L, Lyons PG, Rojas JC, Ciesielski TM, Beach S, Farnan JM, Arora V. PMID: 30636201.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. We May Not "Have It All," But We Can Make It Better through Structural Changes. J Hosp Med. 2018 12; 13(12):877-878. Zapata CB, Santhosh L. PMID: 30496331.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. 1322. Impact of Hospital Medicine on Trends in Infectious Diseases and Other Subspecialty Fellowship Applications. Open Forum Infectious Diseases. 2018 Nov 26; 5(suppl_1):s404-s404. Santhosh SL, Babik BJ. .
      View in: Publisher Site   Mentions:
    41. Diving Into Diagnostic Uncertainty: Strategies to Mitigate Cognitive Load: In Reference to: "Focused Ethnography of Diagnosis in Academic Medical Centers". J Hosp Med. 2018 11; 13(11):804. Santhosh L, Raffel K, Ranji SR. PMID: 30484782.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Practical Tips for ICU Bedside Teaching. Chest. 2018 10; 154(4):760-765. Santhosh L, Brown W, Ferreira J, Niroula A, Carlos WG. PMID: 30290929.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Tissue Isn't the Issue. J Hosp Med. 2018 07 01; 13(7):500-504. Santhosh L, Koth L, Baudendistel TE, Sharpe B, Monash B. PMID: 29694457.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Intensive Care Unit Educators: A Multicenter Evaluation of Behaviors Residents Value in Attending Physicians. Ann Am Thorac Soc. 2017 Apr; 14(4):513-516. Santhosh L, Jain S, Brady A, Sharp M, Carlos WG. PMID: 28287827.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Whither the Pulmonary Ward Attending? Preserving Subspecialty Exposure in United States Internal Medicine Residency Training. Ann Am Thorac Soc. 2017 Apr; 14(4):565-568. Santhosh L, Babik J, Looney MR, Hollander H. PMID: 28362539.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Medicine Enters the Computer Age. Distracted Doctoring. 2017 Jan 1; 5-16. Santhosh SL, Khanna KR. .
      View in: Publisher Site   Mentions:
    47. The “Building Blocks” of Antiretrovirals: Development, Implementation and Evaluation of a Novel Curricular Tool to Teach Trainees About HIV Therapeutics. Open Forum Infectious Diseases. 2015 Dec 9; 2(suppl_1):441. Santhosh SL, Schwartz SB, Chin-Hong CP. .
      View in: Publisher Site   Mentions:
    48. From the sidelines to the frontline: how the Substance Abuse and Mental Health Services Administration embraced smoking cessation. Am J Public Health. 2014 May; 104(5):796-802. Santhosh L, Meriwether M, Saucedo C, Reyes R, Cheng C, Clark B, Tipperman D, Schroeder SA. PMID: 24625143.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    49. Regional distribution and behavioral correlates of 5-HT(2A) receptors in Alzheimer's disease with [(18)F]deuteroaltanserin and PET. Psychiatry Res. 2009 Sep 30; 173(3):212-7. Santhosh L, Estok KM, Vogel RS, Tamagnan GD, Baldwin RM, Mitsis EM, Macavoy MG, Staley JK, van Dyck CH. PMID: 19682865.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    50. Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis. BMC Genet. 2003 Dec 31; 4 Suppl 1:S73. Klein AP, Kovac I, Sorant AJ, Baffoe-Bonnie A, Doan BQ, Ibay G, Lockwood E, Mandal D, Santhosh L, Weissbecker K, Woo J, Zambelli-Weiner A, Zhang J, Naiman DQ, Malley J, Bailey-Wilson JE. PMID: 14975141.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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