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    Chelsea Bahney, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentOrthopaedic Surgery
    Address1001 Potrero Ave, SFGH 9
    San Francisco CA 94110
    Phone415-206-5362
    EmailChelsea.Bahney@ucsf.edu
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      Collapse Biography 
      Collapse Education and Training
      University of Colorado, BoulderBSChemical Engineering 2001
      Oregon Health & Science UniversityPhDStem Cell & Developmental Biology2010
      University of California, San FranciscoPost-Doctoral FellowshipOrthopaedic Surgery2014

      Collapse Overview 
      Collapse Overview
      The focus of my laboratory is to develop translational therapies for the treatment of musculoskeletal diseases and injuries. Specifically, I believe we can drive improved tissue regeneration by recapitulating the normal sequences of development and repair. My background includes training in both Chemical Engineering and Stem Cell & Developmental Biology, and the laboratory is modeled to reflect this interdisciplinary approach to research. Our work aims to utilize biologically modified polymers to promote a sequence of biological milestones that parallel native repair. The long-term goal of our research is to solve problems that will have a direct and significant impact on human health.

      Current Projects:

      (1) Tissue engineering strategies to promote endochondral bone regeneration
      (2) Transdifferentiation of cartilage to bone during fracture repair
      (3) The role of the nerve in fracture repair
      (4) Polytraumatic Injuries: How brain trauma influences fracture healing


      Collapse ORNG Applications 
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bahney CS, Jacobs L, Tamai R, Hu D, Luan TF, Wang M, Reddy S, Park M, Limburg S, Kim HT, Marcucio R, Kuo AC. Promoting Endochondral Bone Repair Using Human Osteoarthritic Articular Chondrocytes. Tissue Eng Part A. 2016 Mar; 22(5-6):427-35. PMID: 26830207.
        View in: PubMed
      2. Marcucio RS, Nauth A, Giannoudis PV, Bahney C, Piuzzi NS, Muschler G, Miclau T. Stem Cell Therapies in Orthopaedic Trauma. J Orthop Trauma. 2015 Dec; 29 Suppl 12:S24-7. PMID: 26584262.
        View in: PubMed
      3. Giannoudis PV, Hak D, Sanders D, Donohoe E, Tosounidis T, Bahney C. Inflammation, Bone Healing, and Anti-Inflammatory Drugs: An Update. J Orthop Trauma. 2015 Dec; 29 Suppl 12:S6-9. PMID: 26584270.
        View in: PubMed
      4. Almubarak S, Nethercott H, Freeberg M, Beaudon C, Jha A, Jackson W, Marcucio R, Miclau T, Healy K, Bahney C. Tissue engineering strategies for promoting vascularized bone regeneration. Bone. 2016 Feb; 83:197-209. PMID: 26608518.
        View in: PubMed
      5. Lin MC, Herfat ST, Bahney CS, Marmor M, Maharbiz MM. Impedance spectroscopy to monitor fracture healing. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:5138-41. PMID: 26737448.
        View in: PubMed
      6. Song S, Kim EJ, Bahney CS, Miclau T, Marcucio R, Roy S. The synergistic effect of micro-topography and biochemical culture environment to promote angiogenesis and osteogenic differentiation of human mesenchymal stem cells. Acta Biomater. 2015 May; 18:100-11. PMID: 25735800.
        View in: PubMed
      7. Bahney, CS; Hu, DP; Miclau, T; Marcucio, RS. . Review Article. The multifaceted role of the vasculature in endochondral fracture repair. 2015.
      8. Bahney CS, Hu DP, Miclau T, Marcucio RS. The multifaceted role of the vasculature in endochondral fracture repair. Front Endocrinol (Lausanne). 2015; 6:4. PMID: 25699016; PMCID: PMC4318416.
      9. Bahney CS, Hu DP, Taylor AJ, Ferro F, Britz HM, Hallgrimsson B, Johnstone B, Miclau T, Marcucio RS. Stem cell-derived endochondral cartilage stimulates bone healing by tissue transformation. J Bone Miner Res. 2014; 29(5):1269-82. PMID: 24259230.
        View in: PubMed
      10. Yu YY, Bahney C, Hu D, Marcucio RS, Miclau T. Creating rigidly stabilized fractures for assessing intramembranous ossification, distraction osteogenesis, or healing of critical sized defects. J Vis Exp. 2012; (62). PMID: 22525683; PMCID: PMC3466651.
      11. Bahney CS, Miclau T. Therapeutic potential of stem cells in orthopedics. Indian J Orthop. 2012 Jan; 46(1):4-9. PMID: 22345800; PMCID: PMC3270604.
      12. Bahney CS, Lujan TJ, Hsu CW, Bottlang M, West JL, Johnstone B. Visible light photoinitiation of mesenchymal stem cell-laden bioresponsive hydrogels. Eur Cell Mater. 2011; 22:43-55; discussion 55. PMID: 21761391.
        View in: PubMed
      13. Bahney CS, Hsu CW, Yoo JU, West JL, Johnstone B. A bioresponsive hydrogel tuned to chondrogenesis of human mesenchymal stem cells. FASEB J. 2011 May; 25(5):1486-96. PMID: 21282205.
        View in: PubMed
      14. Lujan TJ, Wirtz KM, Bahney CS, Madey SM, Johnstone B, Bottlang M. A novel bioreactor for the dynamic stimulation and mechanical evaluation of multiple tissue-engineered constructs. Tissue Eng Part C Methods. 2011 Mar; 17(3):367-74. PMID: 20950252; PMCID: PMC3045075.
      15. Buxton AN, Bahney CS, Yoo JU, Johnstone B. Temporal exposure to chondrogenic factors modulates human mesenchymal stem cell chondrogenesis in hydrogels. Tissue Eng Part A. 2011 Feb; 17(3-4):371-80. PMID: 20799905; PMCID: PMC3028992.
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