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    Claude Hemphill, III, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentNeurology
    Address1001 Potrero Ave, SFGH 5
    San Francisco CA 94143
    Phone415-206-3213

       Biography 
       Awards and Honors
      UCSF2009Kenneth Rainin Endowed Chair in Neurocritical Care
      Department of Neurology, UCSF2006Robert B. Layzer Golden Toe Award for Excellence in Resident Teaching
      Department of Neurosurgery, UCSF2000Diane D. Ralston Clinical and Basic Neuroscience Teaching Award

       Bibliographic 
       Publications
      Publications by year:
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Kamel H, Navi BB, Hemphill JC. A rule to identify patients who require magnetic resonance imaging after intracerebral hemorrhage. Neurocrit Care. 2013 Feb; 18(1):59-63.
        View in: PubMed
      2. Kamel H, Hemphill JC. Characteristics and sequelae of intracranial hypertension after intracerebral hemorrhage. Neurocrit Care. 2012 Oct; 17(2):172-6.
        View in: PubMed
      3. Andrews CM, Jauch EC, Hemphill JC, Smith WS, Weingart SD. Emergency neurological life support: intracerebral hemorrhage. Neurocrit Care. 2012 Sep; 17 Suppl 1:S37-46.
        View in: PubMed
      4. Navi BB, Kamel H, McCulloch CE, Nakagawa K, Naravetla B, Moheet AM, Wong C, Johnston SC, Hemphill JC, Smith WS. Accuracy of neurovascular fellows' prognostication of outcome after subarachnoid hemorrhage. Stroke. 2012 Mar; 43(3):702-7.
        View in: PubMed
      5. Nakagawa K, Hills NK, Kamel H. The effect of decompressive hemicraniectomy on brain temperature after severe brain injury. Neurocrit Care. 2011 Aug; 15(1):101-6.
        View in: PubMed
      6. Bar B, Hemphill JC. Charlson comorbidity index adjustment in intracerebral hemorrhage. Stroke. 2011 Oct; 42(10):2944-6.
        View in: PubMed
      7. Hemphill JC, Andrews P, De Georgia M. Multimodal monitoring and neurocritical care bioinformatics. Nat Rev Neurol. 2011 Aug; 7(8):451-60.
        View in: PubMed
      8. Kamel H, Navi BB, Nakagawa K, Hemphill JC, Ko NU. Hypertonic saline versus mannitol for the treatment of elevated intracranial pressure: a meta-analysis of randomized clinical trials. Crit Care Med. 2011 Mar; 39(3):554-9.
        View in: PubMed
      9. Rosenthal G, Sanchez-Mejia RO, Phan N, Hemphill JC, Martin C, Manley GT. Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury. J Neurosurg. 2011 Jan; 114(1):62-70.
        View in: PubMed
      10. Morgenstern LB, Hemphill JC, Anderson C, Becker K, Broderick JP, Connolly ES, Greenberg SM, Huang JN, MacDonald RL, Messé SR, Mitchell PH, Selim M, Tamargo RJ. Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010 Sep; 41(9):2108-29.
        View in: PubMed
      11. Rabinstein AA, Hemphill JC. Prognosticating after severe acute brain disease: science, art, and biases. Neurology. 2010 Apr 6; 74(14):1086-7.
        View in: PubMed
      12. Levy JH, Dutton RP, Hemphill JC, Shander A, Cooper D, Paidas MJ, Kessler CM, Holcomb JB, Lawson JH. Multidisciplinary approach to the challenge of hemostasis. Anesth Analg. 2010 Feb 1; 110(2):354-64.
        View in: PubMed
      13. Hemphill JC, Farrant M, Neill TA. Prospective validation of the ICH Score for 12-month functional outcome. Neurology. 2009 Oct 6; 73(14):1088-94.
        View in: PubMed
      14. Jichici D, Hemphill JC. Low brain tissue oxygen predicts poor outcome, but does it give insight to possible interventions? Crit Care Med. 2009 Jun; 37(6):2134-5.
        View in: PubMed
      15. Hemphill JC, White DB. Clinical nihilism in neuroemergencies. Emerg Med Clin North Am. 2009 Feb; 27(1):27-37, vii-viii.
        View in: PubMed
      16. Elijovich L, Patel PV, Hemphill JC. Intracerebral hemorrhage. Semin Neurol. 2008 Nov; 28(5):657-67.
        View in: PubMed
      17. Stewart C, Haitsma I, Zador Z, Hemphill JC, Morabito D, Manley G, Rosenthal G. The new Licox combined brain tissue oxygen and brain temperature monitor: assessment of in vitro accuracy and clinical experience in severe traumatic brain injury. Neurosurgery. 2008 Dec; 63(6):1159-64; discussion 1164-5.
        View in: PubMed
      18. Barazangi N, Hemphill JC. Advanced cerebral monitoring in neurocritical care. Neurol India. 2008 Oct-Dec; 56(4):405-14.
        View in: PubMed
      19. Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008 Jun; 36(6):1917-24.
        View in: PubMed
      20. Flint AC, Manley GT, Gean AD, Hemphill JC, Rosenthal G. Post-operative expansion of hemorrhagic contusions after unilateral decompressive hemicraniectomy in severe traumatic brain injury. J Neurotrauma. 2008 May; 25(5):503-12.
        View in: PubMed
      21. Hemphill JC, Ramirez-Arce J. International neurocritical care: report from the Costa Rica Neurointensive and Neuromonitoring Course. Neurocrit Care. 2008; 8(2):308-9.
        View in: PubMed
      22. Rosenthal G, Hemphill JC, Sorani M, Martin C, Morabito D, Meeker M, Wang V, Manley GT. The role of lung function in brain tissue oxygenation following traumatic brain injury. J Neurosurg. 2008 Jan; 108(1):59-65.
        View in: PubMed
      23. Kim J, Smith A, Hemphill JC, Smith WS, Lu Y, Dillon WP, Wintermark M. Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage. AJNR Am J Neuroradiol. 2008 Mar; 29(3):520-5.
        View in: PubMed
      24. Hemphill JC. The need for a registry renaissance in neurocritical care. Crit Care Med. 2007 Sep; 35(9):2208-9.
        View in: PubMed
      25. Kallet RH, Hemphill JC, Dicker RA, Alonso JA, Campbell AR, Mackersie RC, Katz JA. The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injury. Respir Care. 2007 Aug; 52(8):989-95.
        View in: PubMed
      26. Barton CW, Hemphill JC. Cumulative dose of hypertension predicts outcome in intracranial hemorrhage better than American Heart Association guidelines. Acad Emerg Med. 2007 Aug; 14(8):695-701.
        View in: PubMed
      27. Sorani MD, Hemphill JC, Morabito D, Rosenthal G, Manley GT. New approaches to physiological informatics in neurocritical care. Neurocrit Care. 2007; 7(1):45-52.
        View in: PubMed
      28. Flint AC, Hemphill JC, Bonovich DC. Therapeutic hypothermia after cardiac arrest: performance characteristics and safety of surface cooling with or without endovascular cooling. Neurocrit Care. 2007; 7(2):109-18.
        View in: PubMed
      29. Hemphill JC. Do-not-resuscitate orders, unintended consequences, and the ripple effect. Crit Care. 2007; 11(2):121.
        View in: PubMed
      30. Rose JC, Neill TA, Hemphill JC. Continuous monitoring of the microcirculation in neurocritical care: an update on brain tissue oxygenation. Curr Opin Crit Care. 2006 Apr; 12(2):97-102.
        View in: PubMed
      31. Smith WS, Tsao JW, Billings ME, Johnston SC, Hemphill JC, Bonovich DC, Dillon WP. Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia. Neurocrit Care. 2006; 4(1):14-7.
        View in: PubMed
      32. Hemphill JC, Lyden P. Stroke thrombolysis in the elderly: risk or benefit? Neurology. 2005 Dec 13; 65(11):1690-1.
        View in: PubMed
      33. Hemphill JC. Treating warfarin-related intracerebral hemorrhage: is fresh frozen plasma enough? Stroke. 2006 Jan; 37(1):6-7.
        View in: PubMed
      34. Hemphill JC, Bleck T, Carhuapoma JR, Chang C, Diringer M, Geocadin R, Mayer S, Samuels O, Vespa P. Is neurointensive care really optional for comprehensive stroke care? Stroke. 2005 Nov; 36(11):2344-5.
        View in: PubMed
      35. Tsao JW, Hemphill JC, Johnston SC, Smith WS, Bonovich DC. Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke. Arch Neurol. 2005 Jul; 62(7):1126-9.
        View in: PubMed
      36. Hemphill JC, Smith WS, Sonne DC, Morabito D, Manley GT. Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results. AJNR Am J Neuroradiol. 2005 May; 26(5):1095-100.
        View in: PubMed
      37. Hemphill JC, Barton CW, Morabito D, Manley GT. Influence of data resolution and interpolation method on assessment of secondary brain insults in neurocritical care. Physiol Meas. 2005 Aug; 26(4):373-86.
        View in: PubMed
      38. Barton CW, Hemphill JC, Morabito D, Manley G. A novel method of evaluating the impact of secondary brain insults on functional outcomes in traumatic brain-injured patients. Acad Emerg Med. 2005 Jan; 12(1):1-6.
        View in: PubMed
      39. Hemphill JC, Morabito D, Farrant M, Manley GT. Brain tissue oxygen monitoring in intracerebral hemorrhage. Neurocrit Care. 2005; 3(3):260-70.
        View in: PubMed
      40. Hemphill JC, Murthy JM. Report from the Indian Third National Workshop on Critical Care Neurology. Neurocrit Care. 2005; 3(3):282-3.
        View in: PubMed
      41. Hemphill JC, Newman J, Zhao S, Johnston SC. Hospital usage of early do-not-resuscitate orders and outcome after intracerebral hemorrhage. Stroke. 2004 May; 35(5):1130-4.
        View in: PubMed
      42. Clarke JL, Johnston SC, Farrant M, Bernstein R, Tong D, Hemphill JC. External validation of the ICH score. Neurocrit Care. 2004; 1(1):53-60.
        View in: PubMed
      43. Quiñones-Hinojosa A, Binder DK, Hemphill JC, Manley GT. Diagnosis of posttraumatic transverse sinus thrombosis with magnetic resonance imaging/magnetic resonance venography: report of two cases. J Trauma. 2004 Jan; 56(1):201-4.
        View in: PubMed
      44. Hwang W, Ralph J, Marco E, Hemphill JC. Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck. Neurology. 2003 Jun 24; 60(12):2015-6.
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      45. Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM. Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation. Adv Exp Med Biol. 2003; 530:311-7.
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      46. Sumner CJ, Golden JA, Hemphill JC. Should thrombolysis be contraindicated in patients with cerebral arteriovenous malformations? Crit Care Med. 2002 Oct; 30(10):2359-62.
        View in: PubMed
      47. Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT. Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine. Acad Emerg Med. 2002 Oct; 9(10):969-76.
        View in: PubMed
      48. Bernstein RA, Hemphill JC. Critical care of acute ischemic stroke. Curr Neurol Neurosci Rep. 2001 Nov; 1(6):587-92.
        View in: PubMed
      49. Singh V, McCartney JP, Hemphill JC. Transcranial Doppler ultrasonography in the neurologic intensive care unit. Neurol India. 2001 Jun; 49 Suppl 1:S81-9.
        View in: PubMed
      50. Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. 2001 Apr; 32(4):891-7.
        View in: PubMed
      51. Hemphill JC, Knudson MM, Derugin N, Morabito D, Manley GT. Carbon dioxide reactivity and pressure autoregulation of brain tissue oxygen. Neurosurgery. 2001 Feb; 48(2):377-83; discussion 383-4.
        View in: PubMed
      52. Manley GT, Hemphill JC, Morabito D, Derugin N, Erickson V, Pitts LH, Knudson MM. Cerebral oxygenation during hemorrhagic shock: perils of hyperventilation and the therapeutic potential of hypoventilation. J Trauma. 2000 Jun; 48(6):1025-32; discussion 1032-3.
        View in: PubMed
      53. Hemphill JC. Ischemic stroke. Clinical strategies based on mechanisms and risk factors. Geriatrics. 2000 Mar; 55(3):42, 47-8, 51-2.
        View in: PubMed
      54. Hemphill JC, Gress DR, Halbach VV. Endovascular therapy of traumatic injuries of the intracranial cerebral arteries. Crit Care Clin. 1999 Oct; 15(4):811-29.
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      55. Dowd CF, Malek AM, Phatouros CC, Hemphill JC. Application of a rheolytic thrombectomy device in the treatment of dural sinus thrombosis: a new technique. AJNR Am J Neuroradiol. 1999 Apr; 20(4):568-70.
        View in: PubMed
      56. Hemphill JC, Smith WS, Halbach VV. Neurologic manifestations of spinal epidural arteriovenous malformations. Neurology. 1998 Mar; 50(3):817-9.
        View in: PubMed
      57. Hemphill JC. New treatments for stroke. Prog Cardiovasc Nurs. 1998; 13(1):4-15.
        View in: PubMed
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