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Winston Chiong, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.D.2006 Medicine
    New York UniversityPh.D.2005Philosophy
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training
    University of California, San Francisco, CA2017Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    New York University2001  - 2005MacCracken Fellowship
    Woodrow Wilson National Fellowship Foundation2001  - 2002Andrew W. Mellon Fellowship in Humanistic Studies
    American Brain Foundation / Alzheimer's Association2010  - 2012Robert Katzman, MD Clinical Research Training Fellowship in Alzheimer's Research

    Collapse Overview 
    Collapse Overview
    Dr. Winston Chiong is an Associate Professor in the UCSF Department of Neurology Memory and Aging Center, and is principal investigator of the UCSF Decision Lab (https://decisionlab.ucsf.edu). His clinical practice focuses on Alzheimer’s disease, frontotemporal dementia and other cognitive disorders of aging. His research has two main themes: (1) the neural bases of decision-making in the aging brain, focusing on how brain systems involved in financial and medical decisions are influenced by health and disease; and (2) the ethical and policy implications of alterations to brain function, informed by the experiences of patients with brain diseases and those undergoing new brain-based therapies.

    He is Co-Chair of the UCSF Department of Neurology Diversity Committee and is a member of the UCSF Medical Center Ethics Committee. Nationally, he serves on the Neuroethics Working Group of the National Institutes of Health BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Multi-Council Working Group and the American Academy of Neurology’s Ethics, Law and Humanities Committee.

    His work is informed by his interdisciplinary training in clinical medicine, philosophy and cognitive neuroscience. He received his PhD degree in philosophy from New York University and his MD degree from UCSF. He completed an internship in internal medicine at Stanford University and a residency in neurology at UCSF. He then underwent postdoctoral research training in cognitive neuroscience and neuroimaging at UC Berkeley and clinical training in dementia at the UCSF Memory and Aging Center.

    Collapse Research 
    Collapse Research Activities and Funding
    Decision-making abilities in Alzheimer's disease and related dementias: From clinical standards to decision neuroscience
    NIH/NIA R01AG058817Sep 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Decision-making abilities in Alzheimer's disease and related dementias: From clinical standards to decision neuroscience
    NIH R01AG058817Sep 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Achieving ethical integration in the development of novel neurotechnologies
    NIH R01MH114860Sep 13, 2017 - May 31, 2021
    Role: Principal Investigator
    Neuroeconomics of Framing Effects and Risk Attitudes in Early Dementia
    NIH K23AG043553Sep 1, 2013 - May 31, 2018
    Role: Principal Investigator
    Decision-Making in Genetic FTD
    NIH R01AG022983Dec 1, 2003 - Feb 28, 2022
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci. 2021; 15:644593. Vedam-Mai V, Deisseroth K, Giordano J, Lazaro-Munoz G, Chiong W, Suthana N, Langevin JP, Gill J, Goodman W, Provenza NR, Halpern CH, Shivacharan RS, Cunningham TN, Sheth SA, Pouratian N, Scangos KW, Mayberg HS, Horn A, Johnson KA, Butson CR, Gilron R, de Hemptinne C, Wilt R, Yaroshinsky M, Little S, Starr P, Worrell G, Shirvalkar P, Chang E, Volkmann J, Muthuraman M, Groppa S, Kühn AA, Li L, Johnson M, Otto KJ, Raike R, Goetz S, Wu C, Silburn P, Cheeran B, Pathak YJ, Malekmohammadi M, Gunduz A, Wong JK, Cernera S, Wagle Shukla A, Ramirez-Zamora A, Deeb W, Patterson A, Foote KD, Okun MS. PMID: 33953663.
      View in: PubMed   Mentions:
    2. New Ethical and Clinical Challenges in "Closed-Loop" Neuromodulation. Neurology. 2021 Mar 16. Hegde M, Chiong W, Rao VR. PMID: 33727407.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Uncovering social-contextual and individual mental health factors associated with violence via computational inference. Patterns (N Y). 2021 Feb 12; 2(2):100176. Santamaría-García H, Baez S, Aponte-Canencio DM, Pasciarello GO, Donnelly-Kehoe PA, Maggiotti G, Matallana D, Hesse E, Neely A, Zapata JG, Chiong W, Levy J, Decety J, Ibáñez A. PMID: 33659906.
      View in: PubMed   Mentions:
    4. A Qualitative Analysis of Ethical Perspectives on Recruitment and Consent for Human Intracranial Electrophysiology Studies. AJOB Neurosci. 2021 Jan; 12(1):57-67. Mergenthaler JV, Chiong W, Dohan D, Feler J, Lechner CR, Starr PA, Arias JJ. PMID: 33528320.
      View in: PubMed   Mentions:    Fields:    
    5. Novel Neurotechnological Interventions for Pediatric Drug-Resistant Epilepsy: Physician Perspectives. J Child Neurol. 2020 Oct 28; 883073820966935. McDonald PJ, Hrincu V, Connolly MB, Harrison MJ, Ibrahim GM, Naftel RP, Chiong W, Udwadia F, Illes J. PMID: 33111593.
      View in: PubMed   Mentions:    Fields:    
    6. Neurologists' Duties in Planning for Triage of Critical Care Resources during the COVID-19 Pandemic. Ann Neurol. 2020 09; 88(3):431-432. Goss AL, Chiong W, Hemphill JC. PMID: 32686102.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Understanding Advance Directives as a Component of Advance Care Planning. Am J Bioeth. 2020 08; 20(8):67-69. Fong KC, Chiong W. PMID: 32757912.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Insiders and Outsiders: Lessons for Neuroethics from the History of Bioethics. AJOB Neurosci. 2020 Jul-Sep; 11(3):155-166. Chiong W. PMID: 32716746.
      View in: PubMed   Mentions: 1     Fields:    
    9. Caregiver "objective attitude" toward patients with neurodegenerative disease: Consequences for caregiver strain and relationship closeness. Aging Ment Health. 2020 Jun 09; 1-7. Zahir A, Staffaroni AM, Wickham RE, Quinn CM, Sapozhnikova A, Seidman J, Chiong W. PMID: 32515603.
      View in: PubMed   Mentions:    Fields:    
    10. Using care navigation to address caregiver burden in dementia: A qualitative case study analysis. Alzheimers Dement (N Y). 2020; 6(1):e12010. Bernstein A, Merrilees J, Dulaney S, Harrison KL, Chiong W, Ong P, Heunis J, Choi J, Walker R, Feuer JE, Lee K, Dohan D, Bonasera SJ, Miller BL, Possin KL. PMID: 32377557.
      View in: PubMed   Mentions:
    11. Commentary 1: Researcher Integrity and Contrasting Obligations in Interdisciplinary Research. J Empir Res Hum Res Ethics. 2019 12; 14(5):487-489. Chiong W, Haeusermann T. PMID: 31779555.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy. Cortex. 2020 03; 124:54-65. Beagle AJ, Zahir A, Borzello M, Kayser AS, Hsu M, Miller BL, Kramer JH, Chiong W. PMID: 31837518.
      View in: PubMed   Mentions: 2     Fields:    
    13. Ethical Challenges of Risk, Informed Consent, and Posttrial Responsibilities in Human Research With Neural Devices: A Review. JAMA Neurol. 2019 Oct 17. Hendriks S, Grady C, Ramos KM, Chiong W, Fins JJ, Ford P, Goering S, Greely HT, Hutchison K, Kelly ML, Kim SYH, Klein E, Lisanby SH, Mayberg H, Maslen H, Miller FG, Rommelfanger K, Sheth SA, Wexler A. PMID: 31621797.
      View in: PubMed   Mentions: 1     Fields:    
    14. Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial. JAMA Intern Med. 2019 Sep 30. Possin KL, Merrilees JJ, Dulaney S, Bonasera SJ, Chiong W, Lee K, Hooper SM, Allen IE, Braley T, Bernstein A, Rosa TD, Harrison K, Begert-Hellings H, Kornak J, Kahn JG, Naasan G, Lanata S, Clark AM, Chodos A, Gearhart R, Ritchie C, Miller BL. PMID: 31566651.
      View in: PubMed   Mentions: 5     Fields:    
    15. Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Front Neurosci. 2019; 13:936. Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, Pouratian N, Gittis AH, Singer AC, Creed MC, Lazaro-Munoz G, Richardson M, Rossi MA, Cendejas-Zaragoza L, D'Haese PF, Chiong W, Gilron R, Chizeck H, Ko A, Baker KB, Wagenaar J, Harel N, Deeb W, Foote KD, Okun MS. PMID: 31572109.
      View in: PubMed   Mentions:
    16. Variations in Costs of a Collaborative Care Model for Dementia. J Am Geriatr Soc. 2019 12; 67(12):2628-2633. Rosa TD, Possin KL, Bernstein A, Merrilees J, Dulaney S, Matuoka J, Lee KP, Chiong W, Bonasera SJ, Harrison KL, Kahn JG. PMID: 31317539.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Association Between Caregiver Depression and Emergency Department Use Among Patients With Dementia. JAMA Neurol. 2019 Jul 08. Guterman EL, Allen IE, Josephson SA, Merrilees JJ, Dulaney S, Chiong W, Lee K, Bonasera SJ, Miller BL, Possin KL. PMID: 31282955.
      View in: PubMed   Mentions: 1     Fields:    
    18. The costs of dementia subtypes to California Medicare fee-for-service, 2015. Alzheimers Dement. 2019 07; 15(7):899-906. Chen Y, Wilson L, Kornak J, Dudley RA, Merrilees J, Bonasera SJ, Byrne CM, Lee K, Chiong W, Miller BL, Possin KL. PMID: 31175026.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Individual differences in level of wisdom are associated with brain activation during a moral decision-making task. Brain Behav. 2019 06; 9(6):e01302. Thomas ML, Martin AS, Eyler L, Lee EE, Macagno E, Devereaux M, Chiong W, Jeste DV. PMID: 31044549.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia. Neuroimage Clin. 2019; 23:101822. Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW. PMID: 31003069.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. The NIH BRAIN Initiative: Integrating Neuroethics and Neuroscience. Neuron. 2019 02 06; 101(3):394-398. Ramos KM, Grady C, Greely HT, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE, Churchill JD, Gordon JA, Koroshetz WJ. PMID: 30731065.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. The Role of Care Navigators Working with People with Dementia and Their Caregivers. J Alzheimers Dis. 2019; 71(1):45-55. Bernstein A, Harrison KL, Dulaney S, Merrilees J, Bowhay A, Heunis J, Choi J, Feuer JE, Clark AM, Chiong W, Lee K, Braley TL, Bonasera SJ, Ritchie CS, Dohan D, Miller BL, Possin KL. PMID: 31322558.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Neurodegenerative disorders of the human frontal lobes. Handb Clin Neurol. 2019; 163:391-410. Butler PM, Chiong W. PMID: 31590743.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Neuroethics Guiding Principles for the NIH BRAIN Initiative. J Neurosci. 2018 12 12; 38(50):10586-10588. Greely HT, Grady C, Ramos KM, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE. PMID: 30541767.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. The Care Ecosystem: Promoting self-efficacy among dementia family caregivers. Dementia (London). 2020 Aug; 19(6):1955-1973. Merrilees JJ, Bernstein A, Dulaney S, Heunis J, Walker R, Rah E, Choi J, Gawlas K, Carroll S, Ong P, Feuer J, Braley T, Clark AM, Lee K, Chiong W, Bonasera SJ, Miller BL, Possin KL. PMID: 30497302.
      View in: PubMed   Mentions: 5     Fields:    
    26. Informed Consent for the Human Research Subject with a Neurologic Disorder. Semin Neurol. 2018 10; 38(5):539-547. Vaishnav NH, Chiong W. PMID: 30321892.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Neurosurgical Patients as Human Research Subjects: Ethical Considerations in Intracranial Electrophysiology Research. Neurosurgery. 2018 07 01; 83(1):29-37. Chiong W, Leonard MK, Chang EF. PMID: 28973530.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Challenges in Communicating and Understanding Predictive Biomarker Imaging for Alzheimer Disease. JAMA Neurol. 2018 01 01; 75(1):18-19. Chiong W. PMID: 29059264.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Head Positioning in Acute Stroke. N Engl J Med. 2017 09 14; 377(11):1101-2. Feldman WB, Chiong W, Kim SYH. PMID: 28905616.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Response by Feldman et al to Letter Regarding Article, "Trends in Recruitment Rates for Acute Stroke Trials, 1990-2014". Stroke. 2017 06; 48(6):e145. Feldman WB, Kim AS, Chiong W. PMID: 28473632.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem. PLoS Med. 2017 03; 14(3):e1002260. Possin KL, Merrilees J, Bonasera SJ, Bernstein A, Chiong W, Lee K, Wilson L, Hooper SM, Dulaney S, Braley T, Laohavanich S, Feuer JE, Clark AM, Schaffer MW, Schenk AK, Heunis J, Ong P, Cook KM, Bowhay AD, Gearhart R, Chodos A, Naasan G, Bindman AB, Dohan D, Ritchie C, Miller BL. PMID: 28323819.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    32. Trends in Recruitment Rates for Acute Stroke Trials, 1990-2014. Stroke. 2017 03; 48(3):799-801. Feldman WB, Kim AS, Chiong W. PMID: 28104835.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. PMID: 27429218.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    34. Failures to discuss and document preferences: Preventable medical errors in stroke care. Neurology. 2016 05 31; 86(22):2032-3. Xian Y, Chiong W. PMID: 27060164.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Effect of waivers of consent on recruitment in acute stroke trials: A systematic review. Neurology. 2016 04 19; 86(16):1543-51. Feldman WB, Kim AS, Josephson SA, Lowenstein DH, Chiong W. PMID: 27009262.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Racial and Ethnic Differences in Advance Directive Possession: Role of Demographic Factors, Religious Affiliation, and Personal Health Values in a National Survey of Older Adults. J Palliat Med. 2016 Feb; 19(2):149-56. Huang IA, Neuhaus JM, Chiong W. PMID: 26840850.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    37. Neuroeconomic dissociation of semantic dementia and behavioural variant frontotemporal dementia. Brain. 2016 Feb; 139(Pt 2):578-87. Chiong W, Wood KA, Beagle AJ, Hsu M, Kayser AS, Miller BL, Kramer JH. PMID: 26667277.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. Inability to consent does not diminish the desirability of stroke thrombolysis. Ann Neurol. 2014 Aug; 76(2):296-304. Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA. PMID: 24980651.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    39. Testing the presumption of consent to emergency treatment for acute ischemic stroke. JAMA. 2014 Apr 23-30; 311(16):1689-91. Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA. PMID: 24756520.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    40. The salience network causally influences default mode network activity during moral reasoning. Brain. 2013 Jun; 136(Pt 6):1929-41. Chiong W, Wilson SM, D'Esposito M, Kayser AS, Grossman SN, Poorzand P, Seeley WW, Miller BL, Rankin KP. PMID: 23576128.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    41. Financial errors in dementia: testing a neuroeconomic conceptual framework. Neurocase. 2014 Aug; 20(4):389-96. Chiong W, Hsu M, Wudka D, Miller BL, Rosen HJ. PMID: 23550884.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. Dementia and personal identity: implications for decision-making. Handb Clin Neurol. 2013; 118:409-18. Chiong W. PMID: 24182394.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. The self: from philosophy to cognitive neuroscience. Neurocase. 2011 Jun; 17(3):190-200. Chiong W. PMID: 21506043.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    44. Equipoise and the dilemma of randomized clinical trials. N Engl J Med. 2011 05 26; 364(21):2077; author reply 2077. Chiong W. PMID: 21612496.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Therapeutic misconceptions and moral conflict in clinical research. Ann Neurol. 2010 Apr; 67(4):419-21. Chiong W. PMID: 20437575.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. Justifying patient risks associated with medical education. JAMA. 2007 Sep 05; 298(9):1046-8. Chiong W. PMID: 17785649.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. The real problem with equipoise. Am J Bioeth. 2006 Jul-Aug; 6(4):37-47. Chiong W. PMID: 16885104.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    48. Brain death without definitions. Hastings Cent Rep. 2005 Nov-Dec; 35(6):20-30. Chiong W. PMID: 16396202.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. Industry-to-physician marketing and the cost of prescription drugs. Am J Bioeth. 2003; 3(3):W28-W29. Chiong W. PMID: 14594480.
      View in: PubMed   Mentions: 1     Fields:    
    50. MSJAMA: diagnosing and defining disease. JAMA. 2001 Jan 03; 285(1):89-90. Chiong W. PMID: 11150118.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. PHOG, a candidate gene for involvement in the short stature of Turner syndrome. Hum Mol Genet. 1997 Aug; 6(8):1341-7. Ellison JW, Wardak Z, Young MF, Gehron Robey P, Laig-Webster M, Chiong W. PMID: 9259282.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
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