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Winston Chiong, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoM.D.2006 Medicine
    New York UniversityPh.D.2005Philosophy
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training
    University of California, San Francisco, CA2017Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    New York University2001  - 2005MacCracken Fellowship
    Woodrow Wilson National Fellowship Foundation2001  - 2002Andrew W. Mellon Fellowship in Humanistic Studies
    American Brain Foundation / Alzheimer's Association2010  - 2012Robert Katzman, MD Clinical Research Training Fellowship in Alzheimer's Research

    Collapse Overview 
    Collapse Overview
    Dr. Winston Chiong is an Associate Professor in the UCSF Department of Neurology Memory and Aging Center, and is principal investigator of the UCSF Decision Lab (https://decisionlab.ucsf.edu). His clinical practice focuses on Alzheimer’s disease, frontotemporal dementia and other cognitive disorders of aging. His research has two main themes: (1) the neural bases of decision-making in the aging brain, focusing on how brain systems involved in financial and medical decisions are influenced by health and disease; and (2) the ethical and policy implications of alterations to brain function, informed by the experiences of patients with brain diseases and those undergoing new brain-based therapies.

    He is Co-Chair of the UCSF Department of Neurology Diversity Committee, is a member of the UCSF Medical Center Ethics Committee, and co-directs the Ethics, Law and Society Curriculum of the Global Brain Health Institute. Nationally, he serves on the Neuroethics Working Group of the National Institutes of Health BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Multi-Council Working Group and the American Academy of Neurology’s Ethics, Law and Humanities Committee.

    His work is informed by his interdisciplinary training in clinical medicine, philosophy and cognitive neuroscience. He received his PhD degree in philosophy from New York University and his MD degree from UCSF. He completed an internship in internal medicine at Stanford University and a residency in neurology at UCSF. He then underwent postdoctoral research training in cognitive neuroscience and neuroimaging at UC Berkeley and clinical training in dementia at the UCSF Memory and Aging Center.

    Collapse Research 
    Collapse Research Activities and Funding
    Decision-making abilities in Alzheimer's disease and related dementias: From clinical standards to decision neuroscience
    NIH/NIA R01AG058817Sep 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Decision-making abilities in Alzheimer's disease and related dementias: From clinical standards to decision neuroscience
    NIH/NIA R01AG058817Sep 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Achieving ethical integration in the development of novel neurotechnologies
    NIH/NIMH R01MH114860Sep 13, 2017 - May 31, 2021
    Role: Principal Investigator
    Neuroeconomics of Framing Effects and Risk Attitudes in Early Dementia
    NIH/NIA K23AG043553Sep 1, 2013 - May 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hendriks S, Grady C, Ramos KM, Chiong W, Fins JJ, Ford P, Goering S, Greely HT, Hutchison K, Kelly ML, Kim SYH, Klein E, Lisanby SH, Mayberg H, Maslen H, Miller FG, Rommelfanger K, Sheth SA, Wexler A. Ethical Challenges of Risk, Informed Consent, and Posttrial Responsibilities in Human Research With Neural Devices: A Review. JAMA Neurol. 2019 Oct 17. PMID: 31621797.
      View in: PubMed
    2. Possin KL, Merrilees JJ, Dulaney S, Bonasera SJ, Chiong W, Lee K, Hooper SM, Allen IE, Braley T, Bernstein A, Rosa TD, Harrison K, Begert-Hellings H, Kornak J, Kahn JG, Naasan G, Lanata S, Clark AM, Chodos A, Gearhart R, Ritchie C, Miller BL. Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use: The Care Ecosystem Randomized Clinical Trial. JAMA Intern Med. 2019 Sep 30. PMID: 31566651.
      View in: PubMed
    3. Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, Pouratian N, Gittis AH, Singer AC, Creed MC, Lazaro-Munoz G, Richardson M, Rossi MA, Cendejas-Zaragoza L, D'Haese PF, Chiong W, Gilron R, Chizeck H, Ko A, Baker KB, Wagenaar J, Harel N, Deeb W, Foote KD, Okun MS. Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Front Neurosci. 2019; 13:936. PMID: 31572109.
      View in: PubMed
    4. Rosa TD, Possin KL, Bernstein A, Merrilees J, Dulaney S, Matuoka J, Lee KP, Chiong W, Bonasera SJ, Harrison KL, Kahn JG. Variations in Costs of a Collaborative Care Model for Dementia. J Am Geriatr Soc. 2019 Jul 18. PMID: 31317539.
      View in: PubMed
    5. Guterman EL, Allen IE, Josephson SA, Merrilees JJ, Dulaney S, Chiong W, Lee K, Bonasera SJ, Miller BL, Possin KL. Association Between Caregiver Depression and Emergency Department Use Among Patients With Dementia. JAMA Neurol. 2019 Jul 08. PMID: 31282955.
      View in: PubMed
    6. Chen Y, Wilson L, Kornak J, Dudley RA, Merrilees J, Bonasera SJ, Byrne CM, Lee K, Chiong W, Miller BL, Possin KL. The costs of dementia subtypes to California Medicare fee-for-service, 2015. Alzheimers Dement. 2019 Jul; 15(7):899-906. PMID: 31175026.
      View in: PubMed
    7. Thomas ML, Martin AS, Eyler L, Lee EE, Macagno E, Devereaux M, Chiong W, Jeste DV. Individual differences in level of wisdom are associated with brain activation during a moral decision-making task. Brain Behav. 2019 Jun; 9(6):e01302. PMID: 31044549.
      View in: PubMed
    8. Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW. Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia. Neuroimage Clin. 2019; 23:101822. PMID: 31003069.
      View in: PubMed
    9. Ramos KM, Grady C, Greely HT, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE, Churchill JD, Gordon JA, Koroshetz WJ. The NIH BRAIN Initiative: Integrating Neuroethics and Neuroscience. Neuron. 2019 02 06; 101(3):394-398. PMID: 30731065.
      View in: PubMed
    10. Bernstein A, Harrison KL, Dulaney S, Merrilees J, Bowhay A, Heunis J, Choi J, Feuer JE, Clark AM, Chiong W, Lee K, Braley TL, Bonasera SJ, Ritchie CS, Dohan D, Miller BL, Possin KL. The Role of Care Navigators Working with People with Dementia and Their Caregivers. J Alzheimers Dis. 2019; 71(1):45-55. PMID: 31322558.
      View in: PubMed
    11. Butler PM, Chiong W. Neurodegenerative disorders of the human frontal lobes. Handb Clin Neurol. 2019; 163:391-410. PMID: 31590743.
      View in: PubMed
    12. Greely HT, Grady C, Ramos KM, Chiong W, Eberwine J, Farahany NA, Johnson LSM, Hyman BT, Hyman SE, Rommelfanger KS, Serrano EE. Neuroethics Guiding Principles for the NIH BRAIN Initiative. J Neurosci. 2018 12 12; 38(50):10586-10588. PMID: 30541767.
      View in: PubMed
    13. Merrilees JJ, Bernstein A, Dulaney S, Heunis J, Walker R, Rah E, Choi J, Gawlas K, Carroll S, Ong P, Feuer J, Braley T, Clark AM, Lee K, Chiong W, Bonasera SJ, Miller BL, Possin KL. The Care Ecosystem: Promoting self-efficacy among dementia family caregivers. Dementia (London). 2018 Nov 29; 1471301218814121. PMID: 30497302.
      View in: PubMed
    14. Vaishnav NH, Chiong W. Informed Consent for the Human Research Subject with a Neurologic Disorder. Semin Neurol. 2018 10; 38(5):539-547. PMID: 30321892.
      View in: PubMed
    15. Chiong W, Leonard MK, Chang EF. Neurosurgical Patients as Human Research Subjects: Ethical Considerations in Intracranial Electrophysiology Research. Neurosurgery. 2018 07 01; 83(1):29-37. PMID: 28973530.
      View in: PubMed
    16. Chiong W. Challenges in Communicating and Understanding Predictive Biomarker Imaging for Alzheimer Disease. JAMA Neurol. 2018 01 01; 75(1):18-19. PMID: 29059264.
      View in: PubMed
    17. Feldman WB, Chiong W, Kim SYH. Head Positioning in Acute Stroke. N Engl J Med. 2017 09 14; 377(11):1101-2. PMID: 28905616.
      View in: PubMed
    18. Feldman WB, Kim AS, Chiong W. Response by Feldman et al to Letter Regarding Article, "Trends in Recruitment Rates for Acute Stroke Trials, 1990-2014". Stroke. 2017 06; 48(6):e145. PMID: 28473632.
      View in: PubMed
    19. Possin KL, Merrilees J, Bonasera SJ, Bernstein A, Chiong W, Lee K, Wilson L, Hooper SM, Dulaney S, Braley T, Laohavanich S, Feuer JE, Clark AM, Schaffer MW, Schenk AK, Heunis J, Ong P, Cook KM, Bowhay AD, Gearhart R, Chodos A, Naasan G, Bindman AB, Dohan D, Ritchie C, Miller BL. Development of an adaptive, personalized, and scalable dementia care program: Early findings from the Care Ecosystem. PLoS Med. 2017 03; 14(3):e1002260. PMID: 28323819.
      View in: PubMed
    20. Feldman WB, Kim AS, Chiong W. Trends in Recruitment Rates for Acute Stroke Trials, 1990-2014. Stroke. 2017 03; 48(3):799-801. PMID: 28104835.
      View in: PubMed
    21. Ranasinghe KG, Rankin KP, Pressman PS, Perry DC, Lobach IV, Seeley WW, Coppola G, Karydas AM, Grinberg LT, Shany-Ur T, Lee SE, Rabinovici GD, Rosen HJ, Gorno-Tempini ML, Boxer AL, Miller ZA, Chiong W, DeMay M, Kramer JH, Possin KL, Sturm VE, Bettcher BM, Neylan M, Zackey DD, Nguyen LA, Ketelle R, Block N, Wu TQ, Dallich A, Russek N, Caplan A, Geschwind DH, Vossel KA, Miller BL. Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurol. 2016 Sep 01; 73(9):1078-88. PMID: 27429218.
      View in: PubMed
    22. Xian Y, Chiong W. Failures to discuss and document preferences: Preventable medical errors in stroke care. Neurology. 2016 05 31; 86(22):2032-3. PMID: 27060164.
      View in: PubMed
    23. Feldman WB, Kim AS, Josephson SA, Lowenstein DH, Chiong W. Effect of waivers of consent on recruitment in acute stroke trials: A systematic review. Neurology. 2016 04 19; 86(16):1543-51. PMID: 27009262.
      View in: PubMed
    24. Huang IA, Neuhaus JM, Chiong W. Racial and Ethnic Differences in Advance Directive Possession: Role of Demographic Factors, Religious Affiliation, and Personal Health Values in a National Survey of Older Adults. J Palliat Med. 2016 Feb; 19(2):149-56. PMID: 26840850.
      View in: PubMed
    25. Chiong W, Wood KA, Beagle AJ, Hsu M, Kayser AS, Miller BL, Kramer JH. Neuroeconomic dissociation of semantic dementia and behavioural variant frontotemporal dementia. Brain. 2016 Feb; 139(Pt 2):578-87. PMID: 26667277.
      View in: PubMed
    26. Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA. Inability to consent does not diminish the desirability of stroke thrombolysis. Ann Neurol. 2014 Aug; 76(2):296-304. PMID: 24980651.
      View in: PubMed
    27. Chiong W, Kim AS, Huang IA, Farahany NA, Josephson SA. Testing the presumption of consent to emergency treatment for acute ischemic stroke. JAMA. 2014 Apr 23-30; 311(16):1689-91. PMID: 24756520.
      View in: PubMed
    28. Chiong W, Wilson SM, D'Esposito M, Kayser AS, Grossman SN, Poorzand P, Seeley WW, Miller BL, Rankin KP. The salience network causally influences default mode network activity during moral reasoning. Brain. 2013 Jun; 136(Pt 6):1929-41. PMID: 23576128.
      View in: PubMed
    29. Chiong W, Hsu M, Wudka D, Miller BL, Rosen HJ. Financial errors in dementia: testing a neuroeconomic conceptual framework. Neurocase. 2014 Aug; 20(4):389-96. PMID: 23550884.
      View in: PubMed
    30. Chiong W. Dementia and personal identity: implications for decision-making. Handb Clin Neurol. 2013; 118:409-18. PMID: 24182394.
      View in: PubMed
    31. Chiong W. The self: from philosophy to cognitive neuroscience. Neurocase. 2011 Jun; 17(3):190-200. PMID: 21506043.
      View in: PubMed
    32. Chiong W. Equipoise and the dilemma of randomized clinical trials. N Engl J Med. 2011 05 26; 364(21):2077; author reply 2077. PMID: 21612496.
      View in: PubMed
    33. Chiong W. Therapeutic misconceptions and moral conflict in clinical research. Ann Neurol. 2010 Apr; 67(4):419-21. PMID: 20437575.
      View in: PubMed
    34. Chiong W. Justifying patient risks associated with medical education. JAMA. 2007 Sep 05; 298(9):1046-8. PMID: 17785649.
      View in: PubMed
    35. Chiong W. The real problem with equipoise. Am J Bioeth. 2006 Jul-Aug; 6(4):37-47. PMID: 16885104.
      View in: PubMed
    36. Chiong W. Brain death without definitions. Hastings Cent Rep. 2005 Nov-Dec; 35(6):20-30. PMID: 16396202.
      View in: PubMed
    37. Chiong W. Industry-to-physician marketing and the cost of prescription drugs. Am J Bioeth. 2003; 3(3):W28-W29. PMID: 14594480.
      View in: PubMed
    38. Chiong W. MSJAMA: diagnosing and defining disease. JAMA. 2001 Jan 03; 285(1):89-90. PMID: 11150118.
      View in: PubMed
    39. Ellison JW, Wardak Z, Young MF, Gehron Robey P, Laig-Webster M, Chiong W. PHOG, a candidate gene for involvement in the short stature of Turner syndrome. Hum Mol Genet. 1997 Aug; 6(8):1341-7. PMID: 9259282.
      View in: PubMed