Loading...

Sarah Knox, PhD

TitleAssistant Professor
SchoolUCSF School of Dentistry
DepartmentCell and Tissue Biology
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-502-0811
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    NIDCRPost-doctoral Fellow2011Laboratory of Cell and Developmental Biology
    University of NSWPhD2002Biomedical Engineering

    Collapse Research 
    Collapse Research Activities and Funding
    Defining the role of immune-neuronal crosstalk in dry eye disease
    NIH/NEI R01EY026492Sep 30, 2016 - Jul 31, 2019
    Role: Principal Investigator
    2016 Proteoglycans Gordon Research Conference & Gordon Research Seminar
    NIH/NIAMS R13AR069957May 1, 2016 - Apr 30, 2017
    Role: Principal Investigator
    Impact of aging on salivary stem cells and organ regeneration
    NIH/NIDCR R21DE025736Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator
    Defining the role of the nervous system in aqueous-deficient dry eye
    NIH/NEI R01EY025980Aug 1, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Neuronal regulation of salivary stem cells
    NIH/NIDCR R01DE024188Apr 1, 2014 - Dec 31, 2018
    Role: Principal Investigator
    Salivary gland repair and regeneration via Schwann cell-nerve interactions
    NIH/NIDCR R21DE022951Jul 20, 2012 - Jun 30, 2014
    Role: Principal Investigator
    Neuronal-epithelial interactions that regulate mouse salivary gland development
    NIH/NIDCR R00DE018969Jan 24, 2012 - Dec 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Featured Presentations

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Mattingly A, Finley JK, Knox SM. Salivary gland development and disease. Wiley Interdiscip Rev Dev Biol. 2015 Nov; 4(6):573-90. PMID: 25970268.
      View in: PubMed
    2. Knosp WM, Knox SM, Lombaert IM, Haddox CL, Patel VN, Hoffman MP. Submandibular parasympathetic gangliogenesis requires sprouty-dependent Wnt signals from epithelial progenitors. Dev Cell. 2015 Mar 23; 32(6):667-77. PMID: 25805134; PMCID: PMC4374127 [Available on 03/23/16].
    3. Finley JK, Farmer D, Emmerson E, Cruz Pacheco N, Knox SM. Manipulating the murine lacrimal gland. J Vis Exp. 2014; (93):e51970. PMID: 25490187.
      View in: PubMed
    4. Nedvetsky PI, Emmerson E, Finley JK, Ettinger A, Cruz-Pacheco N, Prochazka J, Haddox CL, Northrup E, Hodges C, Mostov KE, Hoffman MP, Knox SM. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland. Dev Cell. 2014 Aug 25; 30(4):449-62. PMID: 25158854; PMCID: PMC4155578.
    5. Knox SM, Lombaert IM, Haddox CL, Abrams SR, Cotrim A, Wilson AJ, Hoffman MP. Parasympathetic stimulation improves epithelial organ regeneration. Nat Commun. 2013; 4:1494. PMID: 23422662; PMCID: PMC3582394.
    6. Knosp WM, Knox SM, Hoffman MP. Salivary gland organogenesis. Wiley Interdiscip Rev Dev Biol. 2012 Jan-Feb; 1(1):69-82. PMID: 23801668.
      View in: PubMed
    7. Lombaert IM, Knox SM, Hoffman MP. Salivary gland progenitor cell biology provides a rationale for therapeutic salivary gland regeneration. Oral Dis. 2011 Jul; 17(5):445-9. PMID: 21223454; PMCID: PMC3375332.
    8. Knox SM, Lombaert IM, Reed X, Vitale-Cross L, Gutkind JS, Hoffman MP. Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis. Science. 2010 Sep 24; 329(5999):1645-7. PMID: 20929848; PMCID: PMC3376907.
    9. Chuang CY, Lord MS, Melrose J, Rees MD, Knox SM, Freeman C, Iozzo RV, Whitelock JM. Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan. Biochemistry. 2010 Jul 6; 49(26):5524-32. PMID: 20507176; PMCID: PMC2900151.
    10. Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, Eftekhari S, Whitelock JM, Elkin M, Vlodavsky I, Hoffman MP. Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development. 2007 Dec; 134(23):4177-86. PMID: 17959718.
      View in: PubMed
    11. Knox S, Ge H, Dimitroff BD, Ren Y, Howe KA, Arsham AM, Easterday MC, Neufeld TP, O'Connor MB, Selleck SB. Mechanisms of TSC-mediated control of synapse assembly and axon guidance. PLoS One. 2007; 2(4):e375. PMID: 17440611; PMCID: PMC1847706.
    12. Knox SM, Whitelock JM. Perlecan: how does one molecule do so many things? Cell Mol Life Sci. 2006 Nov; 63(21):2435-45. PMID: 16952056.
      View in: PubMed
    13. Melrose J, Roughley P, Knox S, Smith S, Lord M, Whitelock J. The structure, location, and function of perlecan, a prominent pericellular proteoglycan of fetal, postnatal, and mature hyaline cartilages. J Biol Chem. 2006 Dec 1; 281(48):36905-14. PMID: 16984910.
      View in: PubMed
    14. Kirkpatrick CA, Knox SM, Staatz WD, Fox B, Lercher DM, Selleck SB. The function of a Drosophila glypican does not depend entirely on heparan sulfate modification. Dev Biol. 2006 Dec 15; 300(2):570-82. PMID: 17055473.
      View in: PubMed
    15. Di Giusto DA, Knox SM, Lai Y, Tyrelle GD, Aung MT, King GC. Multitasking by multivalent circular DNA aptamers. Chembiochem. 2006 Mar; 7(3):535-44. PMID: 16482500.
      View in: PubMed
    16. Melrose J, Smith S, Knox S, Whitelock J. Perlecan, the multidomain HS-proteoglycan of basement membranes, is a prominent pericellular component of ovine hypertrophic vertebral growth plate and cartilaginous endplate chondrocytes. Histochem Cell Biol. 2002 Oct; 118(4):269-80. PMID: 12376823.
      View in: PubMed
    17. Knox S, Merry C, Stringer S, Melrose J, Whitelock J. Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors. J Biol Chem. 2002 Apr 26; 277(17):14657-65. PMID: 11847221.
      View in: PubMed
    Sarah's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _
    Back to TOP