Jolie Chang, MD

Title(s)Associate Professor, Otolaryngology
SchoolSchool of Medicine
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    Collapse Education and Training
    University of California, San Francisco, San Francisco, CA Residency School of Medicine
    University of California, San Francisco, San Francisco, CAM.D. Medicine
    Massachusetts Institute of Technology, Cambridge, MAS.B.Electrical Engineering and Computer Science
    Massachusetts Institute of Technology, Cambridge, MAM.EngElectrical Engineering and Computer Science

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    Collapse Overview
    Jolie L. Chang, MD, is an Associate Professor of Otolaryngology, Head and Neck Surgery and Chief of the Division of Sleep Surgery at the University of California, San Francisco.

    Dr. Chang received her bachelor's and master’s degrees in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology in Cambridge. She then completed her medical degree and residency training at the University of California, San Francisco.

    Dr. Chang has performed research in surgical techniques and outcomes for sialendoscopy and sialolithiasis (salivary stone) therapies including the development of a novel clinical measure for obstructive salivary gland symptoms. She has studied hearing loss and its effect on brain plasticity, auditory function in Parkinson’s disease, and hearing loss in bone diseases. Dr. Chang has completed a Howard Hughes Medical Institute Research Training Fellowship and has won several national and international awards for her research. She has successfully competed for funding from the American Academy of Otolaryngology- Head and Neck Surgery, the Triological Society, and the UCSF Academic Senate. She mentors students and trainees in research and is the Director of Resident Research for the Department of Otolaryngology- Head and Neck Surgery.

    Dr. Chang specializes in sleep apnea surgery and minimally invasive approaches for salivary gland surgery including sialendoscopy. Dr. Chang provides comprehensive evaluations for sleep apnea patients considering surgery and specializes in sleep endoscopy, soft palate surgery, tongue base surgery, snoring surgery, and hypoglossal nerve stimulation implant surgery. She also has clinical expertise in hearing and middle ear disorders and ultrasonography for head and neck disorders.

    Snoring and Obstructive Sleep Apnea, Salivary Gland Surgery and Sialendoscopy, General Otolaryngology.

    Sleep Apnea Surgery, Minimally invasive approaches for salivary gland surgery, including sialendoscopy Ultrasonography for head and neck disorders

    Professional Interests:
    Head and neck surgery, shared decision making, sleep apnea therapy and outcomes, hearing rehabilitation, salivary disorders, minimally invasive salivary gland surgery, sialendoscopy.

    Education and Training:
    • Medical School: University of California, San Francisco
    • Internship: University of California, San Francisco – General Surgery
    • Residency: University of California, San Francisco – Otolaryngology
    Head and Neck Surgery

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Plonowska KA, Gurman ZR, Humphrey A, Chang JL, Ryan WR. One-year outcomes of sialendoscopic-assisted salivary duct surgery for sialadenitis without sialolithiasis. Laryngoscope. 2019 Apr; 129(4):890-896. PMID: 30152080.
      View in: PubMed
    2. Ryan WR, Plonowska KA, Gurman ZR, Aubin-Pouliot A, Chang JL. One-Year symptom outcomes after sialolithiasis treatment with sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2019 Feb; 129(2):396-402. PMID: 30151855.
      View in: PubMed
    3. Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 03; 10(3). PMID: 29335337.
      View in: PubMed
    4. Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR. Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes. Otolaryngol Head Neck Surg. 2017 12; 157(6):973-980. PMID: 28871894.
      View in: PubMed
    5. Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR. Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 12; 127(12):2770-2776. PMID: 28714528.
      View in: PubMed
    6. Ogden MA, Rosbe KW, Chang JL. Pediatric sialendoscopy indications and outcomes. Curr Opin Otolaryngol Head Neck Surg. 2016 Dec; 24(6):529-535. PMID: 27636984.
      View in: PubMed
    7. Jáuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL. Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings. Laryngoscope. 2017 07; 127(7):1565-1570. PMID: 27861944.
      View in: PubMed
    8. Delagnes EA, Aubin-Pouliot A, Zheng M, Chang JL, Ryan WR. Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 05; 127(5):1073-1079. PMID: 27701754.
      View in: PubMed
    9. Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR. Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study. Laryngoscope. 2016 06; 126(6):1343-8. PMID: 26972293.
      View in: PubMed
    10. Chang JL, Pross SE, Findlay AM, Mizuiri D, Henderson-Sabes J, Garrett C, Nagarajan SS, Cheung SW. Spatial plasticity of the auditory cortex in single-sided deafness. Laryngoscope. 2016 12; 126(12):2785-2791. PMID: 26951886.
      View in: PubMed
    11. Heaton CM, Chang JL, Orloff LA. Prognostic Implications of Lymph Node Yield in Central and Lateral Neck Dissections for Well-Differentiated Papillary Thyroid Carcinoma. Thyroid. 2016 Mar; 26(3):434-40. PMID: 26825749.
      View in: PubMed
    12. Pross SE, Chang JL, Mizuiri D, Findlay AM, Nagarajan SS, Cheung SW. Temporal Cortical Plasticity in Single-Sided Deafness: A Functional Imaging Study. Otol Neurotol. 2015 Sep; 36(8):1443-9. PMID: 26196207.
      View in: PubMed
    13. Aubin-Pouliot A, Delagnes EA, Eisele DW, Chang JL, Ryan WR. The Chronic Obstructive Sialadenitis Symptoms Questionnaire to assess sialendoscopy-assisted surgery. Laryngoscope. 2016 Jan; 126(1):93-9. PMID: 26256263.
      View in: PubMed
    14. Dewyer NA, Kiringoda R, Kram YA, Chang JL, Chang CY, Cheung SW. Stapedectomy Effects on Tinnitus: Relationship of Change in Loudness to Change in Severity. Otolaryngol Head Neck Surg. 2015 Dec; 153(6):1019-23. PMID: 26115669.
      View in: PubMed
    15. Rosbe KW, Milev D, Chang JL. Effectiveness and costs of sialendoscopy in pediatric patients with salivary gland disorders. Laryngoscope. 2015 Dec; 125(12):2805-9. PMID: 26010768.
      View in: PubMed
    16. Kiringoda R, Eisele DW, Chang JL. A comparison of parotid imaging characteristics and sialendoscopic findings in obstructive salivary disorders. Laryngoscope. 2014 Dec; 124(12):2696-701. PMID: 24932900.
      View in: PubMed
    17. Akil O, Hall-Glenn F, Chang J, Li A, Chang W, Lustig LR, Alliston T, Hsiao EC. Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia. PLoS One. 2014; 9(5):e94989. PMID: 24788917; PMCID: PMC4006800.
    18. Ryan WR, Chang JL, Eisele DW. Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis. Laryngoscope. 2014 Feb; 124(2):418-20. PMID: 24130099.
      View in: PubMed
    19. Chang JL, Eisele DW. Limited distal sialodochotomy to facilitate sialendoscopy of the submandibular duct. Laryngoscope. 2013 May; 123(5):1163-7. PMID: 23553554.
      View in: PubMed
    20. Chang JL, Kezirian EJ. What are the health risks of untreated snoring without obstructive sleep apnea? Laryngoscope. 2013 Jun; 123(6):1321-2. PMID: 23553233.
      View in: PubMed
    21. Kezirian EJ, Chang JL. Snoring without OSA and health consequences: the jury is still out. Sleep. 2013 Apr 01; 36(4):613. PMID: 23565009; PMCID: PMC3612260.
    22. Alliston, T Chang, J.IBMS BoneKEy. Biological Calibration of Bone Quality for Tissue-Specific Function. 2011; (8):370-380.
    23. Chang JL, Brauer DS, Johnson J, Chen CG, Akil O, Balooch G, Humphrey MB, Chin EN, Porter AE, Butcher K, Ritchie RO, Schneider RA, Lalwani A, Derynck R, Marshall GW, Marshall SJ, Lustig L, Alliston T. Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-ß and Runx2 in bone is required for hearing. EMBO Rep. 2010 Oct; 11(10):765-71. PMID: 20847738; PMCID: PMC2948188.
    24. Akil O, Chang J, Hiel H, Kong JH, Yi E, Glowatzki E, Lustig LR. Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposin. J Neurosci. 2006 Dec 13; 26(50):13076-88. PMID: 17167097.
      View in: PubMed
    25. Heldt T, Chang JL, Chen JJ, Verghese GC, Mark RG. Cycle-averaged dynamics of a periodically driven, closed-loop circulation model. Control Eng Pract. 2005 Sep; 13(9):1163-71. PMID: 16050064.
      View in: PubMed
    26. Chang JL, Lomen-Hoerth C, Murphy J, Henry RG, Kramer JH, Miller BL, Gorno-Tempini ML. A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD. Neurology. 2005 Jul 12; 65(1):75-80. PMID: 16009889.
      View in: PubMed