Jolie Chang, MD

Title(s)Associate Professor, Otolaryngology
SchoolSchool of Medicine
Address2233 Post Street
San Francisco CA 94115
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    University of California, San Francisco, San Francisco, CA Residency School of Medicine
    University of California, San Francisco, San Francisco, CAM.D. Medicine
    Massachusetts Institute of Technology, Cambridge, MAS.B.Electrical Engineering and Computer Science
    Massachusetts Institute of Technology, Cambridge, MAM.EngElectrical Engineering and Computer Science

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    Jolie L. Chang, MD, is an Associate Professor of Otolaryngology, Head and Neck Surgery and Chief of the Division of Sleep Surgery at the University of California, San Francisco.

    Dr. Chang received her bachelor's and master’s degrees in Electrical Engineering and Computer Science from the Massachusetts Institute of Technology in Cambridge. She then completed her medical degree and residency training at the University of California, San Francisco.

    Dr. Chang specializes in sleep apnea surgery and minimally invasive approaches for salivary gland surgery including sialendoscopy. Dr. Chang provides comprehensive and individualized evaluations for patients considering surgery for sleep apnea and specializes in sleep endoscopy, soft palate surgery, tongue base surgery, snoring surgery, and hypoglossal nerve stimulation implant surgery. She also has clinical expertise in ultrasonography for head and neck disorders.

    Dr. Chang performs research in health care decision making and surgical outcomes for sleep apnea therapies. She has published work on surgical techniques and outcomes of minimally invasive sialendoscopy used for sialolithiasis (salivary stone) and duct stenosis treatment. She has studied hearing loss and its effect on brain plasticity, auditory function in bone diseases. Dr. Chang completed a Howard Hughes Medical Institute Research Training Fellowship and has successfully competed for funding from the American Academy of Otolaryngology- Head and Neck Surgery, the Triological Society, and the UCSF Academic Senate. She mentors students and trainees in research and is the Director of Resident Research for the Department of Otolaryngology- Head and Neck Surgery.

    Snoring and Obstructive Sleep Apnea, Salivary Gland Surgery and Sialendoscopy, General Otolaryngology.

    Sleep Apnea Surgery
    Minimally invasive salivary gland surgery
    Ultrasonography for head and neck disorders

    Professional Interests:
    Head and neck surgery, shared decision-making, sleep apnea therapy and outcomes, hearing rehabilitation, salivary disorders, minimally invasive salivary gland surgery, sialendoscopy, ultrasound.

    Education and Training:
    • Medical School: University of California, San Francisco
    • Internship: University of California, San Francisco – General Surgery
    • Residency: University of California, San Francisco – Otolaryngology
    Head and Neck Surgery

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Laryngeal Adductor Reflex Movement Latency Following Tactile Stimulation. Otolaryngol Head Neck Surg. 2021 Jul 13; 1945998211025517. Strohl MP, Chang JL, Dwyer CD, Young VN, Rosen CA, Cheung SW. PMID: 34253075.
      View in: PubMed   Mentions:    Fields:    
    2. Characterizing Decisional Conflict in Patients Presenting to Sleep Surgery Clinic and an Exploration of Resource Limitations. Laryngoscope. 2021 Jun 21. Gulati A, Stephens EM, Cai Y, Chang JL. PMID: 34152601.
      View in: PubMed   Mentions:    Fields:    
    3. Practical Salivary Ultrasound Imaging Tips and Pearls. Otolaryngol Clin North Am. 2021 Jun; 54(3):471-487. Xu MJ, Chang JL. PMID: 34024476.
      View in: PubMed   Mentions:    Fields:    
    4. Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review. Laryngoscope Investig Otolaryngol. 2021 Jun; 6(3):404-413. Strohl MP, Chang CF, Ryan WR, Chang JL. PMID: 34195360.
      View in: PubMed   Mentions:
    5. Patient Use of Low-cost Digital Videoscopes and Smartphones for Remote Ear and Oropharyngeal Examinations. JAMA Otolaryngol Head Neck Surg. 2021 04 01; 147(4):336-342. Cai Y, Zheng YJ, Gulati A, Butrymowicz A, Krauter R, Pletcher SD, Sharon JD, Goldberg AN, Chang JL. PMID: 33475683.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Interhemispheric Auditory Cortical Synchronization in Asymmetric Hearing Loss. Ear Hear. 2021 Mar 26. Chang JL, Crawford ED, Bhutada AS, Henderson Sabes J, Chen J, Cai C, Dale CL, Findlay AM, Mizuiri D, Nagarajan SS, Cheung SW. PMID: 33974786.
      View in: PubMed   Mentions:    Fields:    
    7. Author Correction: Corticostriatal functional connectivity of bothersome tinnitus in single-sided deafness. Sci Rep. 2021 Feb 05; 11(1):3566. Henderson-Sabes J, Shang Y, Perez PL, Chang JL, Pross SE, Findlay AM, Mizuiri D, Hinkley LB, Nagarajan SS, Cheung SW. PMID: 33547372.
      View in: PubMed   Mentions:    Fields:    
    8. Short-term chemosensory distortions and phantoms in COVID-19. Laryngoscope Investig Otolaryngol. 2021 Feb 01. Gurrola JG, Chang JL, Roland LT, Loftus PA, Cheung SW. PMID: 33821217.
      View in: PubMed   Mentions:
    9. Temporal Profile of Olfactory Dysfunction in COVID-19. OTO Open. 2020 Oct-Dec; 4(4):2473974X20978133. Loftus PA, Roland LT, Gurrola JG, Cheung SW, Chang JL. PMID: 33330830.
      View in: PubMed   Mentions:
    10. Metabolic, Radiation, and Medication Induced Sialadenitis. Current Otorhinolaryngology Reports. 2020 Dec 1; 8(4):402-408. Jacqueline E. Harris, Stephen Y. Lai, Jolie L. Chang. .
      View in: Publisher Site   Mentions:
    11. Ear Preference and Interaural Threshold Asymmetry. Otol Neurotol. 2020 12; 41(10):e1178-e1184. Chang JL, Huwyler CM, Cueva KL, Henderson-Sabes J, Cheung SW. PMID: 32810009.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Sialendoscopy in Chronic Obstructive Sialadenitis Without Sialolithiasis: A Prospective Cohort Study. Otolaryngol Head Neck Surg. 2021 03; 164(3):595-601. Plonowska KA, Ochoa E, Ryan WR, Chang JL. PMID: 32988282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Evolving Otolaryngology Resident Roles and Concerns at the Peak of the US COVID-19 Pandemic. Head Neck. 2020 12; 42(12):3712-3719. Cai Y, Gulati A, Jiam NT, Wai KC, Shuman EA, Pletcher SD, Durr ML, Chang JL. PMID: 32926482.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    14. Clinical Entities that Mimic Salivary Inflammatory Disease. Current Otorhinolaryngology Reports. 2020 Sep 1; 8(3):304-310. Daniel E. Palmieri, Barry M. Schaitkin, Jolie L. Chang. .
      View in: Publisher Site   Mentions:
    15. Novel Adaptation of a Validated Tactile Aesthesiometer to Evaluate Laryngopharyngeal Sensation. Laryngoscope. 2021 06; 131(6):1324-1331. Strohl MP, Young VN, Dwyer CD, Bhutada A, Crawford E, Chang JL, Rosen CA, Cheung SW. PMID: 32735711.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Reply to: Challenges in interpreting the diagnostic performance of symptoms to predict COVID-19 status: the case of anosmia. Int Forum Allergy Rhinol. 2020 09; 10(9):1116-1117. Roland LT, Loftus PA, Chang JL. PMID: 32583946.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    17. Smell and taste symptom-based predictive model for COVID-19 diagnosis. Int Forum Allergy Rhinol. 2020 Jul; 10(7):832-838. Roland LT, Gurrola JG, Loftus PA, Cheung SW, Chang JL. PMID: 32363809.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsPHPublic Health
    18. Otolaryngology Resident Practices and Perceptions in the Initial Phase of the U.S. COVID-19 Pandemic. Laryngoscope. 2020 11; 130(11):2550-2557. Cai Y, Jiam NT, Wai KC, Shuman EA, Roland LT, Chang JL. PMID: 32368800.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    19. The Nose and Nasal Breathing in Sleep Apnea. Otolaryngol Clin North Am. 2020 Jun; 53(3):385-395. Cai Y, Goldberg AN, Chang JL. PMID: 32192710.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Corticostriatal functional connectivity of bothersome tinnitus in single-sided deafness. Sci Rep. 2019 12 20; 9(1):19552. Henderson-Sabes J, Shang Y, Perez PL, Chang JL, Pross SE, Findlay AM, Mizuiri D, Hinkley LB, Nagarajan SS, Cheung SW. PMID: 31863033.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. One-Year symptom outcomes after sialolithiasis treatment with sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2019 02; 129(2):396-402. Ryan WR, Plonowska KA, Gurman ZR, Aubin-Pouliot A, Chang JL. PMID: 30151855.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. One-year outcomes of sialendoscopic-assisted salivary duct surgery for sialadenitis without sialolithiasis. Laryngoscope. 2019 04; 129(4):890-896. Plonowska KA, Gurman ZR, Humphrey A, Chang JL, Ryan WR. PMID: 30152080.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med. 2018 03; 10(3). Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM. PMID: 29335337.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    24. Salivary Gland Imaging. Gland-Preserving Salivary Surgery. 2018 Jan 1; 15-26. Jolie L. Chang. .
      View in: Publisher Site   Mentions:
    25. Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes. Otolaryngol Head Neck Surg. 2017 12; 157(6):973-980. Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR. PMID: 28871894.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 12; 127(12):2770-2776. Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR. PMID: 28714528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Pediatric sialendoscopy indications and outcomes. Curr Opin Otolaryngol Head Neck Surg. 2016 Dec; 24(6):529-535. Ogden MA, Rosbe KW, Chang JL. PMID: 27636984.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings. Laryngoscope. 2017 07; 127(7):1565-1570. Jáuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL. PMID: 27861944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery. Laryngoscope. 2017 05; 127(5):1073-1079. Delagnes EA, Aubin-Pouliot A, Zheng M, Chang JL, Ryan WR. PMID: 27701754.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study. Laryngoscope. 2016 06; 126(6):1343-8. Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR. PMID: 26972293.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Spatial plasticity of the auditory cortex in single-sided deafness. Laryngoscope. 2016 12; 126(12):2785-2791. Chang JL, Pross SE, Findlay AM, Mizuiri D, Henderson-Sabes J, Garrett C, Nagarajan SS, Cheung SW. PMID: 26951886.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Prognostic Implications of Lymph Node Yield in Central and Lateral Neck Dissections for Well-Differentiated Papillary Thyroid Carcinoma. Thyroid. 2016 Mar; 26(3):434-40. Heaton CM, Chang JL, Orloff LA. PMID: 26825749.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Characteristics of oncocytic lipoadenoma of the submandibular gland: a case report. Acta Oto-Laryngologica Case Reports. 2016 Jan 1; 1(1):4-7. Seth E. Pross, Jolie L. Chang, Christine M. Glastonbury, Annemieke van Zante, Khaing Soe Win, David W. Eisele. .
      View in: Publisher Site   Mentions:
    34. Temporal Cortical Plasticity in Single-Sided Deafness: A Functional Imaging Study. Otol Neurotol. 2015 Sep; 36(8):1443-9. Pross SE, Chang JL, Mizuiri D, Findlay AM, Nagarajan SS, Cheung SW. PMID: 26196207.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    35. The Chronic Obstructive Sialadenitis Symptoms Questionnaire to assess sialendoscopy-assisted surgery. Laryngoscope. 2016 Jan; 126(1):93-9. Aubin-Pouliot A, Delagnes EA, Eisele DW, Chang JL, Ryan WR. PMID: 26256263.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Stapedectomy Effects on Tinnitus: Relationship of Change in Loudness to Change in Severity. Otolaryngol Head Neck Surg. 2015 Dec; 153(6):1019-23. Dewyer NA, Kiringoda R, Kram YA, Chang JL, Chang CY, Cheung SW. PMID: 26115669.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Effectiveness and costs of sialendoscopy in pediatric patients with salivary gland disorders. Laryngoscope. 2015 Dec; 125(12):2805-9. Rosbe KW, Milev D, Chang JL. PMID: 26010768.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    38. A comparison of parotid imaging characteristics and sialendoscopic findings in obstructive salivary disorders. Laryngoscope. 2014 Dec; 124(12):2696-701. Kiringoda R, Eisele DW, Chang JL. PMID: 24932900.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia. PLoS One. 2014; 9(5):e94989. Akil O, Hall-Glenn F, Chang J, Li A, Chang W, Lustig LR, Alliston T, Hsiao EC. PMID: 24788917.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis. Laryngoscope. 2014 Feb; 124(2):418-20. Ryan WR, Chang JL, Eisele DW. PMID: 24130099.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. What are the health risks of untreated snoring without obstructive sleep apnea? Laryngoscope. 2013 Jun; 123(6):1321-2. Chang JL, Kezirian EJ. PMID: 23553233.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    42. Limited distal sialodochotomy to facilitate sialendoscopy of the submandibular duct. Laryngoscope. 2013 May; 123(5):1163-7. Chang JL, Eisele DW. PMID: 23553554.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    43. Snoring without OSA and health consequences: the jury is still out. Sleep. 2013 Apr 01; 36(4):613. Kezirian EJ, Chang JL. PMID: 23565009.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. IBMS BoneKEy. Biological Calibration of Bone Quality for Tissue-Specific Function. 2011; (8):370-380. Alliston, T Chang, J. View Publication.
    45. TGFß and Runx2 calibration of bone extracellular matrix quality for tissue-specific function. BoneKEy Reports. 2011 Aug 1; 8(8):370-380. Tamara Alliston, Jolie Chang. .
      View in: Publisher Site   Mentions:
    46. Examination of Bone Ossification Markers in Cochlear Development. The Laryngoscope. 2011 Jan 1; 121(S5):s313-s313. Jolie Chang, Kristin Butcher, Omar Akil, Rich Schneider, Lawrence Lustig, Tamara Alliston. .
      View in: Publisher Site   Mentions:
    47. Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-ß and Runx2 in bone is required for hearing. . 2010 Oct; 11(10):765-71. Chang JL, Brauer DS, Johnson J, Chen CG, Akil O, Balooch G, Humphrey MB, Chin EN, Porter AE, Butcher K, Ritchie RO, Schneider RA, Lalwani A, Derynck R, Marshall GW, Marshall SJ, Lustig L, Alliston T. PMID: 20847738.
      View in: PubMed   Mentions:
    48. Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposin. J Neurosci. 2006 Dec 13; 26(50):13076-88. Akil O, Chang J, Hiel H, Kong JH, Yi E, Glowatzki E, Lustig LR. PMID: 17167097.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    49. Cycle-averaged dynamics of a periodically driven, closed-loop circulation model. Control Eng Pract. 2005 Sep; 13(9):1163-71. Heldt T, Chang JL, Chen JJ, Verghese GC, Mark RG. PMID: 16050064.
      View in: PubMed   Mentions:
    50. A voxel-based morphometry study of patterns of brain atrophy in ALS and ALS/FTLD. Neurology. 2005 Jul 12; 65(1):75-80. Chang JL, Lomen-Hoerth C, Murphy J, Henry RG, Kramer JH, Miller BL, Gorno-Tempini ML. PMID: 16009889.
      View in: PubMed   Mentions: 100     Fields:    Translation:Humans
    51. Cycle-averaged models of cardiovascular dynamics. IFAC Proceedings Volumes. 2003 Aug 1; 36(15):387-392. Thomas Heldt, Jolie L. Chang, George C. Verghese, Roger G. Mark. .
      View in: Publisher Site   Mentions:
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