Andrew Lechner, MD, PhD

Title(s)Clinical Fellow, Medicine
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSE, #1350
San Francisco CA 94143
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    Collapse Biography 
    Collapse education and training
    UCLA, Los Angeles, CAB.S.06/2010Molecular, Cell, Developmental Biology
    UCSF, San Francisco, CAPh.D.04/2017Biomedical Sciences
    UCSF, San Francisco, CAM.D.06/2019
    UCSF, San Francisco, CA06/2022Internal Medicine Residency
    UCSF, San Francisco, CAPulmonary and Critical Care Medicine

    Collapse Research 
    Collapse research activities and funding
    Myeloid cell regulation of adult lung alveologenesis post-pneumonectomy
    NIH F30HL131198Aug 11, 2016 - Aug 10, 2018
    Role: Principal Investigator
    Lung Injury and Shock Pathogenesis in Y. pestis Sepsis
    NIH R21AI059099Jul 1, 2005 - Jun 30, 2009
    Role: Principal Investigator
    PHYSIOLOGY OF THE LUNG IN STARVATION
    NIH R01HL037386Dec 1, 1986 - Nov 30, 1990
    Role: Principal Investigator
    LUNG DEVELOPMENT DURING INTRAUTERINE ETHANOL EXPOSURE
    NIH R03AA007024Sep 29, 1986 - Sep 28, 1987
    Role: Principal Investigator
    LUNG STRUCTURE AND FUNCTION IN PERINATAL MALNUTRITION
    NIH R23HL029640Jan 1, 1983 - Dec 31, 1985
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Plastic Bronchitis in Adult and Pediatric Patients: A Review of its Presentation, Diagnosis, and Treatment. Mo Med. 2021 Jul-Aug; 118(4):363-373. Patel N, Patel M, Inja R, Krvavac A, Lechner AJ. PMID: 34373673; PMCID: PMC8343636.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    2. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy. Cell Stem Cell. 2017 07 06; 21(1):120-134.e7. Lechner AJ, Driver IH, Lee J, Conroy CM, Nagle A, Locksley RM, Rock JR. PMID: 28506464; PMCID: PMC5501755.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    3. Persistent Pathology in Influenza-Infected Mouse Lungs. Am J Respir Cell Mol Biol. 2016 10; 55(4):613-615. Kanegai CM, Xi Y, Donne ML, Gotts JE, Driver IH, Amidzic G, Lechner AJ, Jones KD, Vaughan AE, Chapman HA, Rock JR. PMID: 27689795; PMCID: PMC5070109.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    4. Evidence for lung epithelial stem cell niches. BMC Dev Biol. 2015 Sep 16; 15:32. Donne ML, Lechner AJ, Rock JR. PMID: 26376663; PMCID: PMC4574358.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    5. Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis. Eur J Pharmacol. 2014 Oct 05; 740:346-52. Wilson CN, Vance CO, Lechner MG, Matuschak GM, Lechner AJ. PMID: 25041842; PMCID: PMC4147868.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    6. Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Dev Cell. 2012 Mar 13; 22(3):651-9. Chhabra A, Lechner AJ, Ueno M, Acharya A, Van Handel B, Wang Y, Iruela-Arispe ML, Tallquist MD, Mikkola HK. PMID: 22387002; PMCID: PMC3395466.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    7. A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis. Innate Immun. 2012 Jun; 18(3):373-89. Wilson CN, Vance CO, Doyle TM, Brink DS, Matuschak GM, Lechner AJ. PMID: 21862597; PMCID: PMC3362682.
      View in: PubMed   Mentions: 3     Fields:    
    8. Septic shock and nonpulmonary organ dysfunction in pneumonic plague: the role of Yersinia pestis pCD1- vs. pgm- virulence factors. Crit Care Med. 2010 Jul; 38(7):1574-83. Doyle TM, Matuschak GM, Lechner AJ. PMID: 20400901.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    9. Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment. Mo Med. 2010 Jul-Aug; 107(4):252-8. Matuschak GM, Lechner AJ. PMID: 20806836; PMCID: PMC6188356.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    10. Acute hypoxia decreases E. coli LPS-induced cytokine production and NF-kappaB activation in alveolar macrophages. Respir Physiol Neurobiol. 2010 Jun 30; 172(1-2):63-71. Matuschak GM, Nayak R, Doyle TM, Lechner AJ. PMID: 20470909; PMCID: PMC2885487.
      View in: PubMed   Mentions: 3     Fields:    
    11. Lipopolysaccharide and cyclic AMP regulation of CB(2) cannabinoid receptor levels in rat brain and mouse RAW 264.7 macrophages. J Neuroimmunol. 2006 Dec; 181(1-2):82-92. Mukhopadhyay S, Das S, Williams EA, Moore D, Jones JD, Zahm DS, Ndengele MM, Lechner AJ, Howlett AC. PMID: 17045344.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    12. Teaching principles of cardiovascular function in a medical student laboratory. Adv Physiol Educ. 2005 Jun; 29(2):118-27. Gupta S, Westfall TC, Lechner AJ, Knuepfer MM. PMID: 15905157.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    13. Hypoxic suppression of E. coli-induced NF-kappa B and AP-1 transactivation by oxyradical signaling. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R437-45. Matuschak GM, Lechner AJ, Chen Z, Todi S, Doyle TM, Loftis LL. PMID: 15059791.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Cocaine enhances susceptibility to endotoxemic shock in a subset of rats. Crit Care Med. 2004 Jan; 32(1):175-83. Knuepfer MM, Bloodgood TA, Matuschak GM, Lechner AJ. PMID: 14707577.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    15. Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines. Crit Care Med. 2003 Jan; 31(1):237-45. Macarthur H, Couri DM, Wilken GH, Westfall TC, Lechner AJ, Matuschak GM, Chen Z, Salvemini D. PMID: 12545022.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
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