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Andrew Lechner, MD, PhD

Title(s)Resident Physician, Medicine
SchoolSchool of Medicine
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    Myeloid cell regulation of adult lung alveologenesis post-pneumonectomy
    NIH/NHLBI F30HL131198Aug 11, 2016 - Aug 10, 2018
    Role: Principal Investigator
    Lung Injury and Shock Pathogenesis in Y. pestis Sepsis
    NIH/NIAID R21AI059099Jul 1, 2005 - Jun 30, 2009
    Role: Principal Investigator
    PHYSIOLOGY OF THE LUNG IN STARVATION
    NIH/NHLBI R01HL037386Dec 1, 1986 - Nov 30, 1990
    Role: Principal Investigator
    LUNG DEVELOPMENT DURING INTRAUTERINE ETHANOL EXPOSURE
    NIH/NIAAA R03AA007024Sep 29, 1986 - Sep 28, 1987
    Role: Principal Investigator
    LUNG STRUCTURE AND FUNCTION IN PERINATAL MALNUTRITION
    NIH/NHLBI R23HL029640Jan 1, 1983 - Dec 31, 1985
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lechner AJ, Driver IH, Lee J, Conroy CM, Nagle A, Locksley RM, Rock JR. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy. Cell Stem Cell. 2017 07 06; 21(1):120-134.e7. PMID: 28506464.
      View in: PubMed
    2. Kanegai CM, Xi Y, Donne ML, Gotts JE, Driver IH, Amidzic G, Lechner AJ, Jones KD, Vaughan AE, Chapman HA, Rock JR. Persistent Pathology in Influenza-Infected Mouse Lungs. Am J Respir Cell Mol Biol. 2016 10; 55(4):613-615. PMID: 27689795.
      View in: PubMed
    3. Donne ML, Lechner AJ, Rock JR. Evidence for lung epithelial stem cell niches. BMC Dev Biol. 2015 Sep 16; 15:32. PMID: 26376663.
      View in: PubMed
    4. Wilson CN, Vance CO, Lechner MG, Matuschak GM, Lechner AJ. Adenosine A1 receptor antagonist, L-97-1, improves survival and protects the kidney in a rat model of cecal ligation and puncture induced sepsis. Eur J Pharmacol. 2014 Oct 05; 740:346-52. PMID: 25041842.
      View in: PubMed
    5. Chhabra A, Lechner AJ, Ueno M, Acharya A, Van Handel B, Wang Y, Iruela-Arispe ML, Tallquist MD, Mikkola HK. Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Dev Cell. 2012 Mar 13; 22(3):651-9. PMID: 22387002.
      View in: PubMed
    6. Wilson CN, Vance CO, Doyle TM, Brink DS, Matuschak GM, Lechner AJ. A novel post-exposure medical countermeasure L-97-1 improves survival and acute lung injury following intratracheal infection with Yersinia pestis. Innate Immun. 2012 Jun; 18(3):373-89. PMID: 21862597.
      View in: PubMed
    7. Matuschak GM, Lechner AJ. Acute lung injury and the acute respiratory distress syndrome: pathophysiology and treatment. Mo Med. 2010 Jul-Aug; 107(4):252-8. PMID: 20806836.
      View in: PubMed
    8. Doyle TM, Matuschak GM, Lechner AJ. Septic shock and nonpulmonary organ dysfunction in pneumonic plague: the role of Yersinia pestis pCD1- vs. pgm- virulence factors. Crit Care Med. 2010 Jul; 38(7):1574-83. PMID: 20400901.
      View in: PubMed
    9. Matuschak GM, Nayak R, Doyle TM, Lechner AJ. Acute hypoxia decreases E. coli LPS-induced cytokine production and NF-kappaB activation in alveolar macrophages. Respir Physiol Neurobiol. 2010 Jun 30; 172(1-2):63-71. PMID: 20470909.
      View in: PubMed
    10. Mukhopadhyay S, Das S, Williams EA, Moore D, Jones JD, Zahm DS, Ndengele MM, Lechner AJ, Howlett AC. Lipopolysaccharide and cyclic AMP regulation of CB(2) cannabinoid receptor levels in rat brain and mouse RAW 264.7 macrophages. J Neuroimmunol. 2006 Dec; 181(1-2):82-92. PMID: 17045344.
      View in: PubMed
    11. Gupta S, Westfall TC, Lechner AJ, Knuepfer MM. Teaching principles of cardiovascular function in a medical student laboratory. Adv Physiol Educ. 2005 Jun; 29(2):118-27. PMID: 15905157.
      View in: PubMed
    12. Matuschak GM, Lechner AJ, Chen Z, Todi S, Doyle TM, Loftis LL. Hypoxic suppression of E. coli-induced NF-kappa B and AP-1 transactivation by oxyradical signaling. Am J Physiol Regul Integr Comp Physiol. 2004 Aug; 287(2):R437-45. PMID: 15059791.
      View in: PubMed
    13. Knuepfer MM, Bloodgood TA, Matuschak GM, Lechner AJ. Cocaine enhances susceptibility to endotoxemic shock in a subset of rats. Crit Care Med. 2004 Jan; 32(1):175-83. PMID: 14707577.
      View in: PubMed
    14. Macarthur H, Couri DM, Wilken GH, Westfall TC, Lechner AJ, Matuschak GM, Chen Z, Salvemini D. Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines. Crit Care Med. 2003 Jan; 31(1):237-45. PMID: 12545022.
      View in: PubMed
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