Tien Peng, MD
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Title(s) | Assistant Professor, Medicine |
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School | School of Medicine |
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Address | 513 Parnassus Ave, HSE San Francisco CA 94143
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Phone | 415-502-4852 |
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ORCID
.gif) | 0000-0002-2226-4635  |
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vCard | Download vCard |
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Biography University of Virginia | B.A. | 2000 | | Johns Hopkins University | M.D. | 2006 | School of Medicine | Columbia University Medical Center | Internal Medicine Residency | 2009 | | University of Pennsylvania | Clinical/Postdoctoral Fellowship | 2015 | Pulmonary Medicine/Cell and Developmental Biology |
Federation of American Societies for Experimental Biology | 2014 | | Jo Rae Wright Award | American Society for Clinical Investigation | 2016 | | Young Physician Scientist Award | National Institutes of Health | 2016
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| 2021 | NIH New Innovator Award |
Overview The Peng Lab is interested in how the mesenchymal compartment integrates extracellular cues to modify the niche, with a focus on the niche supporting resident tissue stem cells. We utilize complex murine genetic models and human specimen to interrogate how mesenchymal compartments maintain organ homeostasis, initiate disease, and drive tissue aging. Tien is a pulmonologist by training and the lab utilizes the lung as a model organ due to its immense cellular diversity and architectural complexity.
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung. Nat Cell Biol. 2020 Nov; 22(11):1295-1306.
Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. PMID: 33046884.
View in: PubMed Mentions: Fields:
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The Role of Hedgehog Signaling in Adult Lung Regeneration and Maintenance. J Dev Biol. 2019 Jul 09; 7(3).
Wang C, Cassandras M, Peng T. PMID: 31323955.
View in: PubMed Mentions:
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Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. 2019 03 19; 50(3):707-722.e6.
Dahlgren MW, Jones SW, Cautivo KM, Dubinin A, Ortiz-Carpena JF, Farhat S, Yu KS, Lee K, Wang C, Molofsky AV, Tward AD, Krummel MF, Peng T, Molofsky AB. PMID: 30824323.
View in: PubMed Mentions: 30 Fields: Translation: AnimalsCells
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Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a. Aging Cell. 2019 06; 18(3):e12914.
Kim SJ, Shan P, Hwangbo C, Zhang Y, Min JN, Zhang X, Ardito T, Li A, Peng T, Sauler M, Lee PJ. PMID: 30790400.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
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Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 10 01; 128(10):4343-4358.
Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. PMID: 29999500.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation. Cell Rep. 2016 11 22; 17(9):2312-2325.
Frank DB, Peng T, Zepp JA, Snitow M, Vincent TL, Penkala IJ, Cui Z, Herriges MJ, Morley MP, Zhou S, Lu MM, Morrisey EE. PMID: 27880906.
View in: PubMed Mentions: 52 Fields: Translation: AnimalsCells
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Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration. Nature. 2015 Oct 22; 526(7574):578-82.
Peng T, Frank DB, Kadzik RS, Morley MP, Rathi KS, Wang T, Zhou S, Cheng L, Lu MM, Morrisey EE. PMID: 26436454.
View in: PubMed Mentions: 55 Fields: Translation: AnimalsCells
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Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15; 28(12):1363-79.
PMID: 24939938.
View in: PubMed Mentions: 61 Fields: Translation: HumansAnimalsCells
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Distinct functions for Wnt/ß-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell. 2013 Dec 05; 13(6):720-33.
PMID: 24315444.
View in: PubMed Mentions: 85 Fields: Translation: AnimalsCells
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Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature. 2013 Aug 29; 500(7464):589-92.
PMID: 23873040.
View in: PubMed Mentions: 63 Fields: Translation: AnimalsCells
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Development of the pulmonary vasculature: Current understanding and concepts for the future. Pulm Circ. 2013 Jan; 3(1):176-8.
PMID: 23662197.
View in: PubMed Mentions:
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Plasma levels of S100A4 in portopulmonary hypertension. Biomarkers. 2009 May; 14(3):156-60.
Peng T, Zamanian R, Krowka MJ, Benza RL, Roberts KE, Taichman DB, Rybak D, Trotter JF, Brown RS, Fallon MB, Kawut SM. PMID: 19399660.
View in: PubMed Mentions: 4 Fields: Translation: Humans
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Herpes simplex encephalitis in a patient with recurrent pituitary adenoma receiving radiation therapy. Am J Clin Oncol. 2007 Dec; 30(6):664-5.
Peng T, Blakeley J, Cingolani E, Griffiths E, Grossman SA. PMID: 18091066.
View in: PubMed Mentions: 1 Fields: Translation: Humans
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The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas. J Natl Cancer Inst. 2007 Apr 18; 99(8):639-52.
Ngo TT, Peng T, Liang XJ, Akeju O, Pastorino S, Zhang W, Kotliarov Y, Zenklusen JC, Fine HA, Maric D, Wen PY, De Girolami U, Black PM, Wu WW, Shen RF, Jeffries NO, Kang DW, Park JK. PMID: 17440165.
View in: PubMed Mentions: 19 Fields: Translation: HumansCells
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Short hairpin RNA loop design for the facilitation of sequence verification. Biotechniques. 2006 Feb; 40(2):154, 156, 158.
Akeju O, Peng T, Park JK. PMID: 16526403.
View in: PubMed Mentions: Fields: Translation: Cells
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Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther. 2003 Jun; 7(6):827-38.
Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L. PMID: 12788657.
View in: PubMed Mentions: 57 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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2003 | 1 | 2006 | 1 | 2007 | 2 | 2009 | 1 | 2013 | 3 | 2014 | 1 | 2015 | 1 | 2016 | 1 | 2018 | 1 | 2019 | 3 | 2020 | 1 |
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This graph shows the number and percent of publications by field.
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