Vincent Auyeung • UCSF Profiles

Vincent Auyeung, MD, PhD

Title(s)	Assistant Professor, Medicine
School	School of Medicine
Address	1700 4th St, #204B San Francisco CA 94158
ORCID	0000-0001-6273-1595
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Biography

Education and Training

Caltech, Pasadena, CA	BS	06/2005	Biology
MIT, Cambridge, MA	PhD	06/2012	Molecular Biology
Harvard Medical School, Boston, MA	MD	06/2014	Medicine
UCSF, San Francisco, CA	Residency	06/2016	Internal Medicine
UCSF, San Francisco, CA	Fellowship		Pulmonary and Critical Care Medicine

Research

Research Activities and Funding

IRE1? mediated dysregulation of the pulmonary epithelium in lung fibrosis
NIH K08HL157654Mar 15, 2021 - Feb 28, 2026
Role: Principal Investigator

The unfolded protein response and TGF-Beta signaling in pulmonary fibrosis
NIH F32HL145990Mar 1, 2019 - Feb 28, 2021
Role: Principal Investigator

ORNG Applications

Collaboration Interests

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2022 04 01; 322(4):L564-L580. Auyeung VC, Downey MS, Thamsen M, Wenger TA, Backes BJ, Sheppard D, Papa FR. PMID: 35170357; PMCID: PMC8957349.

View in: PubMed Mentions: 5 Fields:
Cel Cell Biology Mol Molecular Biology Phy Physiology Pul Pulmonary Medicine
Translation:Humans
ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 11; 17(11):1148-1156. Feldman HC, Ghosh R, Auyeung VC, Mueller JL, Kim JH, Potter ZE, Vidadala VN, Perera BGK, Olivier A, Backes BJ, Zikherman J, Papa FR, Maly DJ. PMID: 34556859; PMCID: PMC8551014.

View in: PubMed Mentions: 2 Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
Stuck in a Moment: Does Abnormal Persistence of Epithelial Progenitors Drive Pulmonary Fibrosis? Am J Respir Crit Care Med. 2021 03 15; 203(6):667-669. Auyeung VC, Sheppard D. PMID: 33226835; PMCID: PMC7958518.

View in: PubMed Mentions: 8 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans Cells
Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29. Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. PMID: 32511538; PMCID: PMC7273306.

View in: PubMed Mentions:
Small Molecules to Improve ER Proteostasis in Disease. Trends Pharmacol Sci. 2019 09; 40(9):684-695. Gonzalez-Teuber V, Albert-Gasco H, Auyeung VC, Papa FR, Mallucci GR, Hetz C. PMID: 31377018.

View in: PubMed Mentions: 31 Fields:
Pha Pharmacology
Translation:Humans Animals Cells
Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung. PLoS One. 2019; 14(1):e0209824. Thamsen M, Ghosh R, Auyeung VC, Brumwell A, Chapman HA, Backes BJ, Perara G, Maly DJ, Sheppard D, Papa FR. PMID: 30625178; PMCID: PMC6326459.

View in: PubMed Mentions: 24 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell. 2013 Feb 14; 152(4):844-58. Auyeung VC, Ulitsky I, McGeary SE, Bartel DP. PMID: 23415231; PMCID: PMC3707628.

View in: PubMed Mentions: 218 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 2010 May 15; 24(10):992-1009. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. PMID: 20413612; PMCID: PMC2867214.

View in: PubMed Mentions: 441 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19857-62. D'Alise AM, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, Mathis D. PMID: 19073938; PMCID: PMC2604930.

View in: PubMed Mentions: 103 Fields:
Sci Science
Translation:Animals Cells
Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. Mol Ther. 2006 Oct; 14(4):494-504. An DS, Qin FX, Auyeung VC, Mao SH, Kung SK, Baltimore D, Chen IS. PMID: 16844419; PMCID: PMC2562632.

View in: PubMed Mentions: 82 Fields:
Mol Molecular Biology The Therapeutics
Translation:Humans Animals Cells
A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10195-200. Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester HA. PMID: 15218096; PMCID: PMC454187.

View in: PubMed Mentions: 45 Fields:
Sci Science
Translation:Animals Cells