Vincent Auyeung, MD, PhD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address1700 4th St
San Francisco CA 94158
ORCID ORCID Icon0000-0001-6273-1595 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Caltech, Pasadena, CABS06/2005Biology
    MIT, Cambridge, MAPhD06/2012Molecular Biology
    Harvard Medical School, Boston, MAMD06/2014Medicine
    UCSF, San Francisco, CAResidency06/2016Internal Medicine
    UCSF, San Francisco, CAFellowshipPulmonary and Critical Care Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    IRE1? mediated dysregulation of the pulmonary epithelium in lung fibrosis
    NIH K08HL157654Mar 15, 2021 - Feb 28, 2026
    Role: Principal Investigator
    The unfolded protein response and TGF-Beta signaling in pulmonary fibrosis
    NIH F32HL145990Mar 1, 2019 - Feb 28, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2022 04 01; 322(4):L564-L580. Auyeung VC, Downey MS, Thamsen M, Wenger TA, Backes BJ, Sheppard D, Papa FR. PMID: 35170357; PMCID: PMC8957349.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 11; 17(11):1148-1156. Feldman HC, Ghosh R, Auyeung VC, Mueller JL, Kim JH, Potter ZE, Vidadala VN, Perera BGK, Olivier A, Backes BJ, Zikherman J, Papa FR, Maly DJ. PMID: 34556859; PMCID: PMC8551014.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Stuck in a Moment: Does Abnormal Persistence of Epithelial Progenitors Drive Pulmonary Fibrosis? Am J Respir Crit Care Med. 2021 03 15; 203(6):667-669. Auyeung VC, Sheppard D. PMID: 33226835; PMCID: PMC7958518.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    4. Management and Outcomes of Critically-Ill Patients with COVID-19 Pneumonia at a Safety-net Hospital in San Francisco, a Region with Early Public Health Interventions: A Case Series. medRxiv. 2020 May 29. Vanderburg S, Alipanah N, Crowder R, Yoon C, Wang R, Thakur N, Slown K, Shete PB, Rofael M, Metcalfe JZ, Merrifield C, Marquez C, Malcolm K, Lipnick M, Jain V, Gomez A, Burns G, Brown LB, Berger C, Auyeung V, Cattamanchi A, Hendrickson CM. PMID: 32511538; PMCID: PMC7273306.
      View in: PubMed   Mentions:
    5. Small Molecules to Improve ER Proteostasis in Disease. Trends Pharmacol Sci. 2019 09; 40(9):684-695. Gonzalez-Teuber V, Albert-Gasco H, Auyeung VC, Papa FR, Mallucci GR, Hetz C. PMID: 31377018.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    6. Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung. PLoS One. 2019; 14(1):e0209824. Thamsen M, Ghosh R, Auyeung VC, Brumwell A, Chapman HA, Backes BJ, Perara G, Maly DJ, Sheppard D, Papa FR. PMID: 30625178; PMCID: PMC6326459.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    7. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell. 2013 Feb 14; 152(4):844-58. Auyeung VC, Ulitsky I, McGeary SE, Bartel DP. PMID: 23415231; PMCID: PMC3707628.
      View in: PubMed   Mentions: 208     Fields:    Translation:HumansAnimalsCells
    8. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 2010 May 15; 24(10):992-1009. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. PMID: 20413612; PMCID: PMC2867214.
      View in: PubMed   Mentions: 424     Fields:    Translation:HumansAnimalsCells
    9. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19857-62. D'Alise AM, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, Mathis D. PMID: 19073938; PMCID: PMC2604930.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    10. Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. Mol Ther. 2006 Oct; 14(4):494-504. An DS, Qin FX, Auyeung VC, Mao SH, Kung SK, Baltimore D, Chen IS. PMID: 16844419; PMCID: PMC2562632.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    11. A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10195-200. Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester HA. PMID: 15218096; PMCID: PMC454187.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
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