Fan Xia, PhD

Title(s)Assistant Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Address550 16th Street
San Francisco CA 94158
Phone--
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    University of Washington, SeattlePhD06/2020Biostatistics

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    Most of my past and current research is oriented around causal mediation analysis. A part of my work provides a comprehensive guide to applied statisticians and epidemiologists that can help them navigate the philosophical subtleties and abundant methodology in causal inference. Another part of my work is to develop methodologies for complex causal mediation structures, including mediation analysis with treatment-induced confounding, mediation analysis with multiple mediation pathways, and mediation analysis for longitudinal data, using rigorous statistical theories for semiparametric inference.
    In addition to causal mediation analysis, my research involves causal discovery, which is another important topic in causal inference, and cluster randomized trials with stepped wedge designs, which are related to model-based causal inference with longitudinal data.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Analysis of stepped wedge cluster randomized trials in the presence of a time-varying treatment effect. Stat Med. 2022 Sep 30; 41(22):4311-4339. Kenny A, Voldal EC, Xia F, Heagerty PJ, Hughes JP. PMID: 35774016; PMCID: PMC9481733.
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    2. Random effect misspecification in stepped wedge designs. Clin Trials. 2022 08; 19(4):380-383. Voldal EC, Xia F, Kenny A, Heagerty PJ, Hughes JP. PMID: 35257614; PMCID: PMC9378360.
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    3. Defining And Estimating Principal Stratum Specific Natural Mediation Effects With Semi-competing Risks Data. Statistica Sinica. 2022. Fei Gao, Fan Xia, Kwun Chuen Gary Chan.
    4. Model misspecification in stepped wedge trials: Random effects for time or treatment. Stat Med. 2022 05 10; 41(10):1751-1766. Voldal EC, Xia F, Kenny A, Heagerty PJ, Hughes JP. PMID: 35137437; PMCID: PMC9007853.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Decomposition, identification and multiply robust estimation of natural mediation effects with multiple mediators. Biometrika. 2022. Xia, F., Chan, K.C.G., . View Publication.
    6. A Surrogate Measure for Time-Varying Biomarkers in Randomized Clinical Trials. Mathematics. 2022; 10(4). Zhuang R, Xia F, Wang Y, Chen Y-Q.
    7. Elucidating Pathways Mediating the Relationship Between Male Sex and COVID-19 Severity. Clin Epidemiol. 2022; 14:115-125. Stalter RM, Atluri V, Xia F, Thomas KK, Lan KF, Greninger AL, Patel RC. PMID: 35115840; PMCID: PMC8800564.
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    8. Identification, Semiparametric Efficiency, and Quadruply Robust Estimation in Mediation Analysis with Treatment-Induced Confounding. Journal of the American Statistical Association. 2021; 1--10. Xia, F., Chan, K.C.G. View Publication.
    9. Discussion on "Causal mediation of semicompeting risks" by Yen-Tsung Huang. Biometrics. 2021 12; 77(4):1155-1159. Chan KCG, Gao F, Xia F. PMID: 34510414.
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    10. Power and sample size calculation for stepped-wedge designs with discrete outcomes. Trials. 2021 Sep 06; 22(1):598. Xia F, Hughes JP, Voldal EC, Heagerty PJ. PMID: 34488848; PMCID: PMC8419932.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. swCRTdesign: An RPackage for Stepped Wedge Trial Design and Analysis. Comput Methods Programs Biomed. 2020 Nov; 196:105514. Voldal EC, Hakhu NR, Xia F, Heagerty PJ, Hughes JP. PMID: 32554025; PMCID: PMC8559260.
      View in: PubMed   Mentions: 3     Fields:    
    12. Robust inference for the stepped wedge design. Biometrics. 2020 03; 76(1):119-130. Hughes JP, Heagerty PJ, Xia F, Ren Y. PMID: 31237680; PMCID: PMC7978491.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    13. In what circumstances could nondaily preexposure prophylaxis for HIV substantially reduce program costs? AIDS. 2018 03 27; 32(6):809-818. Mitchell KM, Dimitrov D, Hughes JP, Xia F, Donnell D, Amico KR, Bokoch K, Chitwarakorn A, Bekker LG, Holtz TH, Mannheimer S, Grant RM, Boily MC. PMID: 29424774; PMCID: PMC5854532.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    14. HELOISE: Phase IIIb Randomized Multicenter Study Comparing Standard-of-Care and Higher-Dose Trastuzumab Regimens Combined With Chemotherapy as First-Line Therapy in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma. J Clin Oncol. 2017 Aug 01; 35(22):2558-2567. Shah MA, Xu RH, Bang YJ, Hoff PM, Liu T, Herráez-Baranda LA, Xia F, Garg A, Shing M, Tabernero J. PMID: 28574779.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCTClinical Trials
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