Hyun Jun Yang, PhD

Title(s)Postdoctoral Scholar, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #301A
San Francisco CA 94158
PronounsHe/Him/His
ORCID ORCID Icon0000-0003-2524-2201 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Wisconsin, Madison, Madison, WIB.S.2013Biochemistry
    University of California, Irvine, Irvine, CAPh.D.2019Organic Chemistry
    Collapse awards and honors
    American Peptide Society2019The Peptide Science Poster Award
    University of California, Irvine2018Allergan Graduate Fellowship in Synthetic Organic Chemistry
    BrightFocus Foundation2020  - 2022BrightFocus Alzheimer Postdoctoral Fellowship
    UCSF2020Faculty/Staff Morale Fund
    UCSF2021Sandler Program for Breakthrough Biomedical Research (PBBR)
    BASF2024California Research Alliance (CARA) by BASF program review presentation challenge (1st place)
    UCSF2023Dean’s Apple for Teachers Award
    Rosetta Commons2024Summer RosettaCon 2024 Travel Award
    NIH2024  - 2029Pathway to Independence Awards (K99/R00)

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    Fingerprinting In Vivo and In Vitro Prion Strains
    BrightFocus A136057Sep 1, 2020 - Aug 31, 2022
    Role: Principal investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SuFEx Chemistry Enables Covalent Assembly of a 280-kDa 18-Subunit Pore-Forming Complex. J Am Chem Soc. 2024 Sep 11; 146(36):25047-25057. Schnaider L, Tan S, Singh PR, Capuano F, Scott AJ, Hambley R, Lu L, Yang H, Wallace EJ, Jo H, DeGrado WF. PMID: 39190920.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold. Acta Neuropathol Commun. 2024 06 12; 12(1):94. Ghosh U, Tse E, Yang H, Shi M, Caro CD, Wang F, Merz GE, Prusiner SB, Southworth DR, Condello C. PMID: 38867338; PMCID: PMC11167798.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. De novo design of drug-binding proteins with predictable binding energy and specificity. Science. 2024 04 05; 384(6691):106-112. Lu L, Gou X, Tan SK, Mann SI, Yang H, Zhong X, Gazgalis D, Valdiviezo J, Jo H, Wu Y, Diolaiti ME, Ashworth A, Polizzi NF, DeGrado WF. PMID: 38574125; PMCID: PMC11290694.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    4. De novo design of peptides that bind specific conformers of α-synuclein. Chem Sci. 2024 Jun 05; 15(22):8414-8421. Wallace HM, Yang H, Tan S, Pan HS, Yang R, Xu J, Jo H, Condello C, Polizzi NF, DeGrado WF. PMID: 38846390; PMCID: PMC11151861.
      View in: PubMed   Mentions: 1  
    5. EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Proc Natl Acad Sci U S A. 2023 03 21; 120(12):e2300769120. Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C. PMID: 36927157; PMCID: PMC10041141.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    6. Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides. Chem Sci. 2022 Jun 07; 13(22):6599-6609. Zhang MY, Yang H, Ortiz G, Trnka MJ, Petronikolou N, Burlingame AL, DeGrado WF, Fujimori DG. PMID: 35756531; PMCID: PMC9172573.
      View in: PubMed   Mentions: 8  
    7. Microbowls with Controlled Concavity for Accurate Microscale Mass Spectrometry. Adv Mater. 2022 Mar; 34(12):e2108194. Xu L, Li X, Li W, Chang KC, Yang H, Tao N, Zhang P, Payne EM, Modavi C, Humphries J, Lu CW, Abate AR. PMID: 35045587; PMCID: PMC9028217.
      View in: PubMed   Mentions: 4     Fields:    
    8. Exploration of α/β/γ-peptidomimetics design for BH3 helical domains. Chem Commun (Camb). 2022 Jan 20; 58(7):945-948. Shin YH, Yang H. PMID: 34985060.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    9. Dual antagonists of α5β1/αvβ1 integrin for airway hyperresponsiveness. Bioorg Med Chem Lett. 2020 11 15; 30(22):127578. Sundaram A, Chen C, Isik Reed N, Liu S, Ki Yeon S, McIntosh J, Tang YZ, Yang H, Adler M, Beresis R, Seiple IB, Sheppard D, DeGrado WF, Jo H. PMID: 33007395; PMCID: PMC7700746.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin. J Org Chem. 2020 02 07; 85(3):1331-1339. Yang H, Pishenko AV, Li X, Nowick JS. PMID: 31746604; PMCID: PMC7814697.
      View in: PubMed   Mentions: 8     Fields:    
    11. Antimicrobial Compositions. 2019. James S Nowick, Hyun Jun Yang. .
    12. X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly. J Am Chem Soc. 2018 10 31; 140(43):14028-14032. Yang H, Wierzbicki M, Du Bois DR, Nowick JS. PMID: 30296063; PMCID: PMC6356018.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    13. Antimicrobial compositions (WO2017181179A1). 2017.
    14. X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore. Chem Commun (Camb). 2017 Feb 28; 53(18):2772-2775. Yang H, Du Bois DR, Ziller JW, Nowick JS. PMID: 28217800; PMCID: PMC5381722.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    15. Elucidation of the Teixobactin Pharmacophore. ACS Chem Biol. 2016 07 15; 11(7):1823-6. Yang H, Chen KH, Nowick JS. PMID: 27232661; PMCID: PMC5283680.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
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