Hyun Jun Yang • UCSF Profiles

Hyun Jun Yang, PhD

Title(s)	Postdoctoral Scholar, Institute for Neurodegenerative Diseases
School	School of Medicine
Address	675 Nelson Rising Lane, #301A San Francisco CA 94158
Phone	--
ORCID	0000-0003-2524-2201
vCard	Download vCard

Biography

Education and Training

University of Wisconsin, Madison, Madison, WI	B.S.	2013	Biochemistry
University of California, Irvine, Irvine, CA	Ph.D.	2019	Organic Chemistry

Awards and Honors

American Peptide Society	2019		The Peptide Science Poster Award
University of California, Irvine	2018		Allergan Graduate Fellowship in Synthetic Organic Chemistry
BrightFocus Foundation	2020 -	2022	BrightFocus Alzheimer Postdoctoral Fellowship
UCSF	2020		Faculty/Staff Morale Fund
UCSF	2021		Sandler Program for Breakthrough Biomedical Research (PBBR)

Overview

Websites

	PeptideLinks
	DeGrado lab
	Condello lab

Research

Research Activities and Funding

Fingerprinting In Vivo and In Vitro Prion Strains
BrightFocus A136057Sep 1, 2020 - Aug 31, 2022
Role: Principal investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

De novo design of drug-binding proteins with predictable binding energy and specificity. Science. 2024 Apr 05; 384(6691):106-112. Lu L, Gou X, Tan SK, Mann SI, Yang H, Zhong X, Gazgalis D, Valdiviezo J, Jo H, Wu Y, Diolaiti ME, Ashworth A, Polizzi NF, DeGrado WF. PMID: 38574125.

View in: PubMed Mentions: Fields:
Sci Science
De novo design of drug-binding proteins with predictable binding energy and specificity. bioRxiv. 2023 Dec 23. Lu L, Gou X, Tan SK, Mann SI, Yang H, Zhong X, Gazgalis D, Valdiviezo J, Jo H, Wu Y, Diolaiti ME, Ashworth A, Polizzi NF, DeGrado WF. PMID: 38187746; PMCID: PMC10769398.

View in: PubMed Mentions: 1
EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Proc Natl Acad Sci U S A. 2023 03 21; 120(12):e2300769120. Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C. PMID: 36927157; PMCID: PMC10041141.

View in: PubMed Mentions: 1 Fields:
Sci Science
Translation:Humans Animals
EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. bioRxiv. 2023 Feb 03. Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C. PMID: 36778268; PMCID: PMC9915571.

View in: PubMed Mentions:
Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides. Chem Sci. 2022 Jun 07; 13(22):6599-6609. Zhang MY, Yang H, Ortiz G, Trnka MJ, Petronikolou N, Burlingame AL, DeGrado WF, Fujimori DG. PMID: 35756531; PMCID: PMC9172573.

View in: PubMed Mentions: 8
Microbowls with Controlled Concavity for Accurate Microscale Mass Spectrometry. Adv Mater. 2022 Mar; 34(12):e2108194. Xu L, Li X, Li W, Chang KC, Yang H, Tao N, Zhang P, Payne EM, Modavi C, Humphries J, Lu CW, Abate AR. PMID: 35045587; PMCID: PMC9028217.

View in: PubMed Mentions: 2 Fields:
Bio Biophysics Che Chemistry
Exploration of α/β/γ-peptidomimetics design for BH3 helical domains. Chem Commun (Camb). 2022 Jan 20; 58(7):945-948. Shin YH, Yang H. PMID: 34985060.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Translation:Cells
Dual antagonists of α5β1/αvβ1 integrin for airway hyperresponsiveness. Bioorg Med Chem Lett. 2020 11 15; 30(22):127578. Sundaram A, Chen C, Isik Reed N, Liu S, Ki Yeon S, McIntosh J, Tang YZ, Yang H, Adler M, Beresis R, Seiple IB, Sheppard D, DeGrado WF, Jo H. PMID: 33007395; PMCID: PMC7700746.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin. J Org Chem. 2020 02 07; 85(3):1331-1339. Yang H, Pishenko AV, Li X, Nowick JS. PMID: 31746604; PMCID: PMC7814697.

View in: PubMed Mentions: 5 Fields:
Che Chemistry
Antimicrobial Compositions. 2019. James S Nowick, Hyun Jun Yang. .
X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-like Assembly. J Am Chem Soc. 2018 10 31; 140(43):14028-14032. Yang H, Wierzbicki M, Du Bois DR, Nowick JS. PMID: 30296063; PMCID: PMC6356018.

View in: PubMed Mentions: 11 Fields:
Che Chemistry
Translation:Cells
Antimicrobial compositions (WO2017181179A1). 2017.
X-ray crystallographic structure of a teixobactin analogue reveals key interactions of the teixobactin pharmacophore. Chem Commun (Camb). 2017 Feb 28; 53(18):2772-2775. Yang H, Du Bois DR, Ziller JW, Nowick JS. PMID: 28217800; PMCID: PMC5381722.

View in: PubMed Mentions: 20 Fields:
Che Chemistry
Translation:Cells
Elucidation of the Teixobactin Pharmacophore. ACS Chem Biol. 2016 07 15; 11(7):1823-6. Yang H, Chen KH, Nowick JS. PMID: 27232661; PMCID: PMC5283680.

View in: PubMed Mentions: 29 Fields:
Bio Biochemistry Bio Biology
Translation:Cells