 Aparna Sundaram, MD
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| Title(s) | Assistant Professor, Medicine |
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| School | School of Medicine |
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| Address | 513 Parnassus Ave, HSE
San Francisco CA 94143
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| Phone | 415-514-8363 |
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| vCard | Download vCard |
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 Biography | Northwestern University | B.S. | 2003 | Biomedical Engineering | | Northwestern University | M.D. | 2006 | | | Northwestern University | Internship/Residency | 2009 | Internal Medicine | | University of California, San Francisco | Fellowship | 2012 | Pulmonary and Critical Care Medicine |
Overview Dr. Sundaram is a biomedical engineer, physician, and scientist with an interest in airway smooth muscle biology. Her laboratory focuses on tethering pathways used by muscle to transmit force. Through a more nuanced understanding of pathways that contribute to force transmission and the influence on pro-inflammatory cytokines on regulating these pathways, Dr. Sundaram hopes to identify novel drug targets to mitigate exaggerated airway narrowing in chronic airways diseases. Dr. Sundaram attends in the Moffitt-Long Intensive Care Units where she works with students, residents, and fellows and gives recurring lectures on management of ICU patients.
Dr. Sundaram also serves as the Associate Program Director for the Molecular Medicine Pathway in Internal Medicine. In this capacity she coordinates weekly didactics for physician-scientists in training and establishes mentoring pathways for the next generation of physician-scientists, with a special emphasis on women and minorities underrepresented in science.
Research ORNG Applications Bibliographic
Altmetrics Details
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(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Dual antagonists of a5ß1/avß1 integrin for airway hyperresponsiveness. Bioorg Med Chem Lett. 2020 11 15; 30(22):127578.
Sundaram A, Chen C, Isik Reed N, Liu S, Ki Yeon S, McIntosh J, Tang YZ, Yang H, Adler M, Beresis R, Seiple IB, Sheppard D, DeGrado WF, Jo H. PMID: 33007395.
View in: PubMed Mentions: Fields:
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G protein-regulated endocytic trafficking of adenylyl cyclase type 9. Elife. 2020 06 09; 9.
Lazar AM, Irannejad R, Baldwin TA, Sundaram AB, Gutkind JS, Inoue A, Dessauer CW, Von Zastrow M. PMID: 32515353.
View in: PubMed Mentions: 3 Fields:
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A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion. J Biol Chem. 2019 11 29; 294(48):18232-18243.
Del Cid JS, Reed NI, Molnar K, Liu S, Dang B, Jensen SA, DeGrado W, Handford PA, Sheppard D, Sundaram AB. PMID: 31640988.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
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IL-17A Recruits Rab35 to IL-17R to Mediate PKCa-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility. J Immunol. 2019 03 01; 202(5):1540-1548.
Bulek K, Chen X, Parron V, Sundaram A, Herjan T, Ouyang S, Liu C, Majors A, Zepp J, Gao J, Dongre A, Bodaszewska-Lubas M, Echard A, Aronica M, Carman J, Garantziotis S, Sheppard D, Li X. PMID: 30683702.
View in: PubMed Mentions: 2 Fields: Translation: AnimalsCells
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Targeting integrin a5ß1 ameliorates severe airway hyperresponsiveness in experimental asthma. J Clin Invest. 2017 01 03; 127(1):365-374.
Sundaram A, Chen C, Khalifeh-Soltani A, Atakilit A, Ren X, Qiu W, Jo H, DeGrado W, Huang X, Sheppard D. PMID: 27918306.
View in: PubMed Mentions: 5 Fields: Translation: HumansAnimalsCells
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G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands. Mol Pharmacol. 2017 Feb; 91(2):145-156.
Tsvetanova NG, Trester-Zedlitz M, Newton BW, Riordan DP, Sundaram AB, Johnson JR, Krogan NJ, von Zastrow M. PMID: 27879340.
View in: PubMed Mentions: 6 Fields: Translation: HumansCells
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IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction. J Clin Invest. 2014 Nov; 124(11):4895-8.
Bhattacharya M, Sundaram A, Kudo M, Farmer J, Ganesan P, Khalifeh-Soltani A, Arjomandi M, Atabai K, Huang X, Sheppard D. PMID: 25271629.
View in: PubMed Mentions: 9 Fields: Translation: AnimalsCells
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The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. J Clin Invest. 2013 May; 123(5):2037-48.
Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. PMID: 23543053.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
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The avß6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest. 2012 Feb; 122(2):748-58.
Sugimoto K, Kudo M, Sundaram A, Ren X, Huang K, Bernstein X, Wang Y, Raymond WW, Erle DJ, Abrink M, Caughey GH, Huang X, Sheppard D. PMID: 22232213.
View in: PubMed Mentions: 31 Fields: Translation: HumansAnimalsCells
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| Year | Publications |
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| 2012 | 1 | | 2013 | 1 | | 2014 | 1 | | 2016 | 2 | | 2019 | 2 | | 2020 | 2 |
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This graph shows the number and percent of publications by field.
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