Adam Abate, PhD

Title(s)Professor, Bioengineering
SchoolSchool of Pharmacy
Address1700 4th Street
San Francisco CA 94158
Phone415-476-9819
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    Collapse Biography 
    Collapse Awards and Honors
    Harvard University2000  - 2002Stanley A. Marks Scholar
    NSF2013  - 2018CAREER Award
    NSF, NIMS2013  - 2014US-Japan Young Scientist Exchange Program
    NIH2014  - 2019New Innovator Award

    Collapse Overview 
    Collapse Overview
    Dr. Adam Abate is a physicist who brings a unique research program to the campus. His research employs microfluidics for high-throughput biological applications. He has developed microfluidic methods to create emulsions that consist of droplets of very precise and consistent sizes and to manipulate the processing and contents of individual droplets in different ways. The droplets are used to create micro-compartments, which can be loaded with single cells and other active materials, such as drugs, nutrients, and assay reagents. By chaining together different microdevice components, the droplets can be used as tiny "test tubes" for performing chemical and biological reactions. This allows multiple, independent reactions to take place at the rate of thousands per second, while using minuscule amounts of total reagent. Adam is using this approach for directed evolution, genetic sequencing, and cell sorting.

    Collapse Research 
    Collapse Research Activities and Funding
    Multi-omic dissection of the transcriptional, epigenetic, and proteomic signatures of cells infected with latent HIV
    NIH R01AI149699Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    A platform for engineering peptide ligase for building next generation peptide therapeutics.
    NIH R41GM136037Feb 7, 2020 - Aug 6, 2021
    Role: Principal Investigator
    SINGLE-CELL TRANSCRIPTOMIC ANALYSIS OF HIV-INFECTED CD4 T CELLS IN BLOOD AND LYMPHOID TISSUE USING PCR-ACTIVATED CELL SORTING
    NIH U01AI129206Aug 17, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Accurate and unbiased single cell sequencing with digital droplet MDA
    NIH R01HG008978Sep 9, 2016 - Jun 30, 2019
    Role: Principal Investigator
    Gigapixel digital PCR in Giant Unilamellar Vesicles
    NIH R01EB019453Sep 30, 2014 - Mar 31, 2023
    Role: Principal Investigator
    Microfluidic immunoprofiling for biomarker discovery in rheumatoid arthritis
    NIH DP2AR068129Sep 30, 2014 - Jun 30, 2019
    Role: Principal Investigator
    Accurate, long-read sequencing with droplet-microfluidic barcoding
    NIH R21HG007233Aug 1, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Advancing Whole-Organism Screening for Chemical Modifiers of the Brain
    NIH R21NS082938Feb 1, 2013 - Jan 31, 2016
    Role: Co-Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Accurate Bulk Quantitation of Droplet Digital Polymerase Chain Reaction. Anal Chem. 2021 Jul 27; 93(29):9974-9979. Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. PMID: 34252272.
      View in: PubMed   Mentions:    Fields:    
    2. Modular barcode beads for microfluidic single cell genomics. Sci Rep. 2021 May 25; 11(1):10857. Delley CL, Abate AR. PMID: 34035349.
      View in: PubMed   Mentions: 1     Fields:    
    3. Sequencing Ultrarare Targets with Compound Nucleic Acid Cytometry. Anal Chem. 2021 05 25; 93(20):7422-7429. Sun C, Chang KC, Abate AR. PMID: 33971091.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients. J Exp Med. 2021 Jul 05; 218(7). Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N. PMID: 33951726.
      View in: PubMed   Mentions: 1     Fields:    
    5. Barcoded viral tracing of single-cell interactions in central nervous system inflammation. Science. 2021 04 23; 372(6540). Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, Hewson P, Manganeli Polonio C, Shultis MW, Salem Y, Tjon EC, Fonseca-Castro PH, Borucki DM, Alves de Lima K, Plasencia A, Abate AR, Rosene DL, Hodgetts KJ, Prinz M, Antel JP, Prat A, Quintana FJ. PMID: 33888612.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Precision ejection of microfluidic droplets into air with a superhydrophobic outlet. Lab Chip. 2021 04 20; 21(8):1484-1491. Zhang P, Chang KC, Abate AR. PMID: 33656500.
      View in: PubMed   Mentions:    Fields:    
    7. Protein design-scapes generated by microfluidic DNA assembly elucidate domain coupling in the bacterial histidine kinase CpxA. Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12). Clark IC, Mensa B, Ochs CJ, Schmidt NW, Mravic M, Quintana FJ, DeGrado WF, Abate AR. PMID: 33723045.
      View in: PubMed   Mentions: 1     Fields:    
    8. Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia. Nat Commun. 2021 03 11; 12(1):1583. Demaree B, Delley CL, Vasudevan HN, Peretz CAC, Ruff D, Smith CC, Abate AR. PMID: 33707421.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. Particle Templated Emulsification enables Microfluidic-Free Droplet Assays. J Vis Exp. 2021 03 09; (169). Weisgerber DW, Hatori MN, Abate AR. PMID: 33779600.
      View in: PubMed   Mentions:    Fields:    
    10. Simple, Affordable, and Modular Patterning of Cells using DNA. J Vis Exp. 2021 02 24; (168). Cabral KA, Patterson DM, Scheideler OJ, Cole R, Abate AR, Schaffer DV, Sohn LL, Gartner ZJ. PMID: 33720126.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. High diversity droplet microfluidic libraries generated with a commercial liquid spotter. Sci Rep. 2021 Feb 23; 11(1):4351. Zhang JQ, Siltanen CA, Dolatmoradi A, Sun C, Chang KC, Cole RH, Gartner ZJ, Abate AR. PMID: 33623093.
      View in: PubMed   Mentions:    Fields:    
    12. Accurate bulk quantitation of droplet digital PCR. bioRxiv. 2021 Jan 15. Sun C, Liu L, Vasudevan HN, Chang KC, Abate AR. PMID: 33469578.
      View in: PubMed   Mentions:
    13. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. Sci Rep. 2021 01 12; 11(1):780. Vasudevan HN, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. PMID: 33436939.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Networks of High Aspect Ratio Particles to Direct Colloidal Assembly Dynamics and Cellular Interactions. Adv Funct Mater. 2020 Nov 25; 30(48). Finbloom JA, Demaree B, Abate AR, Desai TA. PMID: 33250685.
      View in: PubMed   Mentions:
    15. High-Definition Single-Cell Printing: Cell-by-Cell Fabrication of Biological Structures. Adv Mater. 2020 Dec; 32(52):e2005346. Zhang P, Abate AR. PMID: 33206435.
      View in: PubMed   Mentions: 2     Fields:    
    16. Single-cell mutation analysis of clonal evolution in myeloid malignancies. Nature. 2020 11; 587(7834):477-482. Miles LA, Bowman RL, Merlinsky TR, Csete IS, Ooi AT, Durruthy-Durruthy R, Bowman M, Famulare C, Patel MA, Mendez P, Ainali C, Demaree B, Delley CL, Abate AR, Manivannan M, Sahu S, Goldberg AD, Bolton KL, Zehir A, Rampal R, Carroll MP, Meyer SE, Viny AD, Levine RL. PMID: 33116311.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    17. Targeted Single-Cell RNA and DNA Sequencing With Fluorescence-Activated Droplet Merger. Anal Chem. 2020 11 03; 92(21):14616-14623. Clark IC, Delley CL, Sun C, Thakur R, Stott SL, Thaploo S, Li Z, Quintana FJ, Abate AR. PMID: 33049138.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. Nat Commun. 2020 09 23; 11(1):4803. Magill ST, Vasudevan HN, Seo K, Villanueva-Meyer JE, Choudhury A, John Liu S, Pekmezci M, Findakly S, Hilz S, Lastella S, Demaree B, Braunstein SE, Bush NAO, Aghi MK, Theodosopoulos PV, Sneed PK, Abate AR, Berger MS, McDermott MW, Lim DA, Ullian EM, Costello JF, Raleigh DR. PMID: 32968068.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Digital droplet PCR accurately quantifies SARS-CoV-2 viral load from crude lysate without nucleic acid purification. medRxiv. 2020 Sep 03. Vasudevan H, Xu P, Servellita V, Miller S, Liu L, Gopez A, Chiu CY, Abate AR. PMID: 32908995.
      View in: PubMed   Mentions:
    20. Microfluidic particle zipper enables controlled loading of droplets with distinct particle types. Lab Chip. 2020 07 14; 20(14):2465-2472. Delley CL, Abate AR. PMID: 32531004.
      View in: PubMed   Mentions: 2     Fields:    
    21. High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing. J Vis Exp. 2020 05 21; (159). Zhang JQ, Chang KC, Liu L, Gartner ZJ, Abate AR. PMID: 32510483.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery. Nucleic Acids Res. 2020 05 07; 48(8):e48. Xu P, Modavi C, Demaree B, Twigg F, Liang B, Sun C, Zhang W, Abate AR. PMID: 32095820.
      View in: PubMed   Mentions:    Fields:    Translation:CellsPHPublic Health
    23. Linked optical and gene expression profiling of single cells at high-throughput. Genome Biol. 2020 02 24; 21(1):49. Zhang JQ, Siltanen CA, Liu L, Chang KC, Gartner ZJ, Abate AR. PMID: 32093753.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    24. Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma. Cell Rep. 2020 02 04; 30(5):1300-1309.e5. Liu SJ, Magill ST, Vasudevan HN, Hilz S, Villanueva-Meyer JE, Lastella S, Daggubati V, Spatz J, Choudhury A, Orr BA, Demaree B, Seo K, Ferris SP, Abate AR, Oberheim Bush NA, Bollen AW, McDermott MW, Costello JF, Raleigh DR. PMID: 32023450.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Discovery of Stable and Selective Antibody Mimetics from Combinatorial Libraries of Polyvalent, Loop-Functionalized Peptoid Nanosheets. ACS Nano. 2020 01 28; 14(1):185-195. Kim JH, Kim SC, Kline MA, Grzincic EM, Tresca BW, Cardiel J, Karbaschi M, Dehigaspitiya DC, Chen Y, Udumula V, Jian T, Murray DJ, Yun L, Connolly MD, Liu J, Ren G, Chen CL, Kirshenbaum K, Abate AR, Zuckermann RN. PMID: 31789500.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    26. OP 1.3 Single-cell transcriptome sequencing of latently-infected cells ex vivo using PCR-activated cell sorting (PACS). Journal of virus eradication. 2019 Dec 1; 5:1-2. E. Boritz, I. Clark, A. Abate, F. Quintana, S. Deeks, D. Douek. .
      View in: Publisher Site   Mentions:
    27. Combined Single-Cell DNA Genotyping and Protein Quantification (DAb-seq) in Acute Myeloid Leukemias Reveals Distinct Immunophenotypic Subsets Among Pathogenic Clones. Blood. 2019 Nov 13; 134(Supplement_1):2088-2088. Benjamin Demaree, Cyrille Delley, Cheryl Peretz, Harish Vasudevan, David Ruff, Aik Ooi, Catherine C. Smith, Adam Abate. .
      View in: Publisher Site   Mentions:
    28. TMOD-27. A NEURAL CREST CELL SUBPOPULATION UNDERLIES INTRATUMOR HETEROGENEITY IN MENINGIOMA. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi268-vi268. Stephen Magill, Harish Vasudevan, Kyounghee Seo, S John Liu, Stephanie Hilz, Javier Villanueva-Meyer, Abrar Choudhury, Benjamin Demaree, Daniel Lim, Steve Braunstein, Nancy Ann Oberheim-Bush, Erik Ullian, Manish Aghi, Philip Theodosopoulos, Patricia Sneed, Adam Abate, Mitchel Berger, Mike McDermott, Joseph Costello, David Raleigh. .
      View in: Publisher Site   Mentions:
    29. Uniform, Large-Area, Highly Ordered Peptoid Monolayer and Bilayer Films for Sensing Applications. Langmuir. 2019 10 22; 35(42):13671-13680. Murray DJ, Kim JH, Grzincic EM, Kim SC, Abate AR, Zuckermann RN. PMID: 31603340.
      View in: PubMed   Mentions: 2     Fields:    
    30. Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport. Sci Rep. 2019 07 09; 9(1):9936. Samy KE, Levy ES, Phong K, Demaree B, Abate AR, Desai TA. PMID: 31289365.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    31. HIGH-RESOLUTION CLONAL ANALYSIS OF TUMORS WITH SIMULTANEOUS SINGLE-CELL DNA SEQUENCING AND CELL SURFACE PHENOTYPING. HemaSphere. 2019 Jun 1; 3:439. D. Eastburn, C. Delley, B. Demaree, D. Dhingra, P. Mendez, D. Ruff, A. Abate. .
      View in: Publisher Site   Mentions:
    32. High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq. Lab Chip. 2019 05 14; 19(10):1838-1849. Liu L, Dalal CK, Heineike BM, Abate AR. PMID: 31020292.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    33. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nat Immunol. 2019 02; 20(2):163-172. Aran D, Looney AP, Liu L, Wu E, Fong V, Hsu A, Chak S, Naikawadi RP, Wolters PJ, Abate AR, Butte AJ, Bhattacharya M. PMID: 30643263.
      View in: PubMed   Mentions: 216     Fields:    Translation:HumansAnimalsCells
    34. Direct quantification of EGFR variant allele frequency in cell-free DNA using a microfluidic-free digital droplet PCR assay. Methods Cell Biol. 2018; 148:119-131. Demaree B, Weisgerber D, Dolatmoradi A, Hatori M, Abate AR. PMID: 30473066.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Microfluidic bead encapsulation above 20 kHz with triggered drop formation. Lab Chip. 2018 12 07; 18(23):3598-3605. Clark IC, Abate AR. PMID: 30362490.
      View in: PubMed   Mentions: 4     Fields:    
    36. Particle-Templated Emulsification for Microfluidics-Free Digital Biology. Anal Chem. 2018 08 21; 90(16):9813-9820. Hatori MN, Kim SC, Abate AR. PMID: 30033717.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    37. An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing. J Vis Exp. 2018 05 23; (135). Demaree B, Weisgerber D, Lan F, Abate AR. PMID: 29889211.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. An Oil-Free Picodrop Bioassay Platform for Synthetic Biology. Sci Rep. 2018 05 21; 8(1):7913. Siltanen CA, Cole RH, Poust S, Chao L, Tyerman J, Kaufmann-Malaga B, Ubersax J, Gartner ZJ, Abate AR. PMID: 29784937.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    39. A comparative analysis of single cell and droplet-based FACS for improving production phenotypes: Riboflavin overproduction in Yarrowia lipolytica. . 2018 05; 47:346-356. Wagner JM, Liu L, Yuan SF, Venkataraman MV, Abate AR, Alper HS. PMID: 29698778.
      View in: PubMed   Mentions:
    40. Concentric electrodes improve microfluidic droplet sorting. Lab Chip. 2018 02 27; 18(5):710-713. Clark IC, Thakur R, Abate AR. PMID: 29383336.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    41. Combined aptamer and transcriptome sequencing of single cells. Sci Rep. 2018 02 13; 8(1):2919. Delley CL, Liu L, Sarhan MF, Abate AR. PMID: 29440771.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    42. Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis. Anal Chem. 2018 01 16; 90(2):1273-1279. Kim SC, Clark IC, Shahi P, Abate AR. PMID: 29256243.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    43. Bulk double emulsification for flow cytometric analysis of microfluidic droplets. Analyst. 2017 Dec 04; 142(24):4618-4622. Sukovich DJ, Kim SC, Ahmed N, Abate AR. PMID: 29131209.
      View in: PubMed   Mentions: 3     Fields:    
    44. PP1.1 Whole genome sequencing of single HIV provirus and its proviral integration site for the study of HIV latency. Journal of virus eradication. 2017 Dec 1; 3:3-4. C. Sun, J. Mullins, A. Abate. .
      View in: Publisher Site   Mentions:
    45. Cell-free extract based optimization of biomolecular circuits with droplet microfluidics. Lab Chip. 2017 09 12; 17(18):3037-3042. Hori Y, Kantak C, Murray RM, Abate AR. PMID: 28770936.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    46. RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes. Nat Commun. 2017 08 23; 8(1):332. Abatemarco J, Sarhan MF, Wagner JM, Lin JL, Liu L, Hassouneh W, Yuan SF, Alper HS, Abate AR. PMID: 28835641.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    47. Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8728-8733. Cole RH, Tang SY, Siltanen CA, Shahi P, Zhang JQ, Poust S, Gartner ZJ, Abate AR. PMID: 28760972.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    48. Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun. Biomicrofluidics. 2017 Jul; 11(4):044107. Karbaschi M, Shahi P, Abate AR. PMID: 28794817.
      View in: PubMed   Mentions:
    49. Measurement of copy number variation in single cancer cells using rapid-emulsification digital droplet MDA. Microsyst Nanoeng. 2017; 3. Kim SC, Premasekharan G, Clark IC, Gemeda HB, Paris PL, Abate AR. PMID: 30147985.
      View in: PubMed   Mentions:
    50. Finding a helix in a haystack: nucleic acid cytometry with droplet microfluidics. Lab Chip. 2017 06 13; 17(12):2032-2045. Clark IC, Abate AR. PMID: 28540956.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    51. Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding. Nat Biotechnol. 2017 Jul; 35(7):640-646. Lan F, Demaree B, Ahmed N, Abate AR. PMID: 28553940.
      View in: PubMed   Mentions: 65     Fields:    
    52. Abseq: Ultrahigh-throughput single cell protein profiling with droplet microfluidic barcoding. Sci Rep. 2017 03 14; 7:44447. Shahi P, Kim SC, Haliburton JR, Gartner ZJ, Abate AR. PMID: 28290550.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    53. Genetic interaction mapping with microfluidic-based single cell sequencing. PLoS One. 2017; 12(2):e0171302. Haliburton JR, Shao W, Deutschbauer A, Arkin A, Abate AR. PMID: 28170417.
      View in: PubMed   Mentions: 6     Fields:    
    54. Sequence specific sorting of DNA molecules with FACS using 3dPCR. Sci Rep. 2017 01 04; 7:39385. Sukovich DJ, Lance ST, Abate AR. PMID: 28051104.
      View in: PubMed   Mentions: 6     Fields:    
    55. Rapid Encapsulation of Cell and Polymer Solutions with Bubble-Triggered Droplet Generation. Macromolecular Chemistry and Physics. 2017 Jan 1; 218(2):1600297. Zihao Yan, Iain C. Clark, Adam R. Abate. .
      View in: Publisher Site   Mentions:
    56. PCR-activated cell sorting as a general, cultivation-free method for high-throughput identification and enrichment of virus hosts. J Virol Methods. 2017 04; 242:14-21. Lim SW, Lance ST, Stedman KM, Abate AR. PMID: 28042018.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    57. Peering below the diffraction limit: robust and specific sorting of viruses with flow cytometry. Virol J. 2016 12 01; 13(1):201. Lance ST, Sukovich DJ, Stedman KM, Abate AR. PMID: 27906039.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    58. Operation of Droplet-Microfluidic Devices with a Lab Centrifuge. Micromachines (Basel). 2016 Sep 06; 7(9). Ahmed N, Sukovich D, Abate AR. PMID: 30404331.
      View in: PubMed   Mentions:
    59. Droplet barcoding for massively parallel single-molecule deep sequencing. Nat Commun. 2016 06 29; 7:11784. Lan F, Haliburton JR, Yuan A, Abate AR. PMID: 27353563.
      View in: PubMed   Mentions: 25     Fields:    
    60. Multicolor Fluorescence Detection for Droplet Microfluidics Using Optical Fibers. J Vis Exp. 2016 05 05; (111). Cole RH, Gartner ZJ, Abate AR. PMID: 27214249.
      View in: PubMed   Mentions: 4     Fields:    
    61. Double Emulsion Generation Using a Polydimethylsiloxane (PDMS) Co-axial Flow Focus Device. J Vis Exp. 2015 Dec 25; (106):e53516. Cole RH, Tran TM, Abate AR. PMID: 26780079.
      View in: PubMed   Mentions: 1     Fields:    
    62. Enhanced sequencing coverage with digital droplet multiple displacement amplification. Nucleic Acids Res. 2016 Apr 20; 44(7):e66. Sidore AM, Lan F, Lim SW, Abate AR. PMID: 26704978.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    63. Patterning microfluidic device wettability with spatially-controlled plasma oxidation. Lab Chip. 2015 Aug 07; 15(15):3163-9. Kim SC, Sukovich DJ, Abate AR. PMID: 26105774.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    64. Compact and modular multicolour fluorescence detector for droplet microfluidics. Lab Chip. 2015 Jul 07; 15(13):2754-8. Cole RH, de Lange N, Gartner ZJ, Abate AR. PMID: 26032595.
      View in: PubMed   Mentions: 4     Fields:    
    65. Dissecting enzyme function with microfluidic-based deep mutational scanning. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):7159-64. Romero PA, Tran TM, Abate AR. PMID: 26040002.
      View in: PubMed   Mentions: 53     Fields:    
    66. Microfluidic droplet enrichment for targeted sequencing. Nucleic Acids Res. 2015 Jul 27; 43(13):e86. Eastburn DJ, Huang Y, Pellegrino M, Sciambi A, Ptácek LJ, Abate AR. PMID: 25873629.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    67. PCR-activated cell sorting for cultivation-free enrichment and sequencing of rare microbes. PLoS One. 2015; 10(1):e0113549. Lim SW, Tran TM, Abate AR. PMID: 25629401.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    68. Accurate microfluidic sorting of droplets at 30 kHz. Lab Chip. 2015 Jan 07; 15(1):47-51. Sciambi A, Abate AR. PMID: 25352174.
      View in: PubMed   Mentions: 41     Fields:    
    69. Rapid modulation of droplet composition with pincer microvalves. Lab Chip. 2015 Jan 07; 15(1):52-6. Ochs CJ, Abate AR. PMID: 25385230.
      View in: PubMed   Mentions: 4     Fields:    
    70. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood. 2015 Jan 15; 125(3):516-24. Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo TA, Loh ML. PMID: 25395418.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    71. Identification and genetic analysis of cancer cells with PCR-activated cell sorting. Nucleic Acids Res. 2014; 42(16):e128. Eastburn DJ, Sciambi A, Abate AR. PMID: 25030902.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    72. Picoinjection of microfluidic drops without metal electrodes. J Vis Exp. 2014 Apr 18; (86). O'Donovan B, Tran T, Sciambi A, Abate A. PMID: 24797680.
      View in: PubMed   Mentions: 1     Fields:    
    73. Generating electric fields in PDMS microfluidic devices with salt water electrodes. Lab Chip. 2014 Aug 07; 14(15):2605-9. Sciambi A, Abate AR. PMID: 24671446.
      View in: PubMed   Mentions: 21     Fields:    
    74. Coaxial flow focusing in poly(dimethylsiloxane) microfluidic devices. Biomicrofluidics. 2014 Jan; 8(1):016502. Tran TM, Cater S, Abate AR. PMID: 24753732.
      View in: PubMed   Mentions:
    75. DNA sequence analysis with droplet-based microfluidics. Lab Chip. 2013 Dec 21; 13(24):4864-9. Abate AR, Hung T, Sperling RA, Mary P, Rotem A, Agresti JJ, Weiner MA, Weitz DA. PMID: 24185402.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    76. Ultrahigh-throughput sorting of microfluidic drops with flow cytometry. Lab Chip. 2013 Dec 07; 13(23):4563-72. Lim SW, Abate AR. PMID: 24146020.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    77. Ultrahigh-throughput Mammalian single-cell reverse-transcriptase polymerase chain reaction in microfluidic drops. Anal Chem. 2013 Aug 20; 85(16):8016-21. Eastburn DJ, Sciambi A, Abate AR. PMID: 23885761.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    78. Adding reagent to droplets with controlled rupture of encapsulated double emulsions. Biomicrofluidics. 2013; 7(4):44112. Sciambi A, Abate AR. PMID: 24404045.
      View in: PubMed   Mentions:
    79. Picoinjection enables digital detection of RNA with droplet rt-PCR. PLoS One. 2013; 8(4):e62961. Eastburn DJ, Sciambi A, Abate AR. PMID: 23658657.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    80. Block-and-break generation of microdroplets with fixed volume. Biomicrofluidics. 2013; 7(2):24108. van Steijn V, Korczyk PM, Derzsi L, Abate AR, Weitz DA, Garstecki P. PMID: 24404013.
      View in: PubMed   Mentions:
    81. From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology. Journal of Physics D. 2013 Mar 20; 46(11):114004. T M Tran, F Lan, C S Thompson, A R Abate. .
      View in: Publisher Site   Mentions:
    82. Adhesive-based bonding technique for PDMS microfluidic devices. Lab Chip. 2013 Feb 21; 13(4):632-5. Thompson CS, Abate AR. PMID: 23282717.
      View in: PubMed   Mentions: 5     Fields:    
    83. Flow focusing geometry generates droplets through a plug and squeeze mechanism. Lab Chip. 2012 Dec 21; 12(24):5130-2. Romero PA, Abate AR. PMID: 23117576.
      View in: PubMed   Mentions: 5     Fields:    
    84. Drop formation in non-planar microfluidic devices. Lab Chip. 2012 Nov 07; 12(21):4263-8. Rotem A, Abate AR, Utada AS, Van Steijn V, Weitz DA. PMID: 22864475.
      View in: PubMed   Mentions: 14     Fields:    
    85. Electrode-free picoinjection of microfluidic drops. Lab Chip. 2012 Oct 21; 12(20):4029-32. O'Donovan B, Eastburn DJ, Abate AR. PMID: 22930333.
      View in: PubMed   Mentions: 16     Fields:    
    86. Microfluidic synthesis of advanced microparticles for encapsulation and controlled release. Lab Chip. 2012 Jun 21; 12(12):2135-45. Duncanson WJ, Lin T, Abate AR, Seiffert S, Shah RK, Weitz DA. PMID: 22510961.
      View in: PubMed   Mentions: 40     Fields:    
    87. Experimental validation of plugging during drop formation in a T-junction. Lab Chip. 2012 Apr 21; 12(8):1516-21. Abate AR, Mary P, van Steijn V, Weitz DA. PMID: 22402628.
      View in: PubMed   Mentions: 6     Fields:    
    88. High throughput production of single core double emulsions in a parallelized microfluidic device. Lab Chip. 2012 Feb 21; 12(4):802-7. Romanowsky MB, Abate AR, Rotem A, Holtze C, Weitz DA. PMID: 22222423.
      View in: PubMed   Mentions: 39     Fields:    
    89. Measuring the elastic modulus of microgels using microdrops. Soft Matter. 2012 Jan 1; 8(39):10032-10035. Adam R. Abate, Lloyd Han, Lihua Jin, Zhigang Suo, David A. Weitz. .
      View in: Publisher Site   Mentions:
    90. Non-coalescence of oppositely charged droplets in pH-sensitive emulsions. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):384-9. Liu T, Seiffert S, Thiele J, Abate AR, Weitz DA, Richtering W. PMID: 22203968.
      View in: PubMed   Mentions: 4     Fields:    
    91. Efficient encapsulation with plug-triggered drop formation. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Sep; 84(3 Pt 1):031502. Abate AR, Rotem A, Thiele J, Weitz DA. PMID: 22060374.
      View in: PubMed   Mentions: 1     Fields:    
    92. Observation of spatial propagation of amyloid assembly from single nuclei. Proc Natl Acad Sci U S A. 2011 Sep 06; 108(36):14746-51. Knowles TP, White DA, Abate AR, Agresti JJ, Cohen SI, Sperling RA, De Genst EJ, Dobson CM, Weitz DA. PMID: 21876182.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    93. Early development drug formulation on a chip: fabrication of nanoparticles using a microfluidic spray dryer. Lab Chip. 2011 Jul 21; 11(14):2362-8. Thiele J, Windbergs M, Abate AR, Trebbin M, Shum HC, Förster S, Weitz DA. PMID: 21617823.
      View in: PubMed   Mentions: 2     Fields:    
    94. On-chip background noise reduction for cell-based assays in droplets. Lab Chip. 2011 Jun 21; 11(12):2066-70. Mary P, Chen A, Chen I, Abate AR, Weitz DA. PMID: 21541376.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    95. Faster multiple emulsification with drop splitting. Lab Chip. 2011 Jun 07; 11(11):1911-5. Abate AR, Weitz DA. PMID: 21505660.
      View in: PubMed   Mentions: 14     Fields:    
    96. Controlling droplet incubation using close-packed plug flow. Biomicrofluidics. 2011 Apr 04; 5(2):24101. Mary P, Abate AR, Agresti JJ, Weitz DA. PMID: 21544238.
      View in: PubMed   Mentions:
    97. Air-bubble-triggered drop formation in microfluidics. Lab Chip. 2011 May 21; 11(10):1713-6. Abate AR, Weitz DA. PMID: 21448493.
      View in: PubMed   Mentions: 5     Fields:    
    98. Syringe-vacuum microfluidics: A portable technique to create monodisperse emulsions. Biomicrofluidics. 2011 Mar 16; 5:14107. Abate AR, Weitz DA. PMID: 21483661.
      View in: PubMed   Mentions:
    99. Synthesis of monodisperse microparticles from non-Newtonian polymer solutions with microfluidic devices. . 2011 Apr 19; 23(15):1757-60. Abate AR, Kutsovsky M, Seiffert S, Windbergs M, Pinto LF, Rotem A, Utada AS, Weitz DA. PMID: 21394794.
      View in: PubMed   Mentions:
    100. One-step formation of multiple emulsions in microfluidics. Lab Chip. 2011 Jan 21; 11(2):253-8. Abate AR, Thiele J, Weitz DA. PMID: 20967395.
      View in: PubMed   Mentions: 9     Fields:    
    101. High-throughput injection with microfluidics using picoinjectors. Proc Natl Acad Sci U S A. 2010 Nov 09; 107(45):19163-6. Abate AR, Hung T, Mary P, Agresti JJ, Weitz DA. PMID: 20962271.
      View in: PubMed   Mentions: 106     Fields:    
    102. Fabrication of polymersomes using double-emulsion templates in glass-coated stamped microfluidic devices. Small. 2010 Aug 16; 6(16):1723-7. Thiele J, Abate AR, Shum HC, Bachtler S, Förster S, Weitz DA. PMID: 20665757.
      View in: PubMed   Mentions: 11     Fields:    
    103. Patterning microfluidic device wettability using flow confinement. Lab Chip. 2010 Jul 21; 10(14):1774-6. Abate AR, Thiele J, Weinhart M, Weitz DA. PMID: 20490412.
      View in: PubMed   Mentions: 12     Fields:    
    104. Microfluidic sorting with high-speed single-layer membrane valves. Applied Physics Letters. 2010 May 17; 96(20):203509. Adam R. Abate, Jeremy J. Agresti, David A. Weitz. .
      View in: Publisher Site   Mentions:
    105. Smart microgel capsules from macromolecular precursors. J Am Chem Soc. 2010 May 12; 132(18):6606-9. Seiffert S, Thiele J, Abate AR, Weitz DA. PMID: 20397695.
      View in: PubMed   Mentions: 13     Fields:    
    106. Functional patterning of PDMS microfluidic devices using integrated chemo-masks. Lab Chip. 2010 Jun 21; 10(12):1521-4. Romanowsky MB, Heymann M, Abate AR, Krummel AT, Fraden S, Weitz DA. PMID: 20454730.
      View in: PubMed   Mentions: 2     Fields:    
    107. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4004-9. Agresti JJ, Antipov E, Abate AR, Ahn K, Rowat AC, Baret JC, Marquez M, Klibanov AM, Griffiths AD, Weitz DA. PMID: 20142500.
      View in: PubMed   Mentions: 225     Fields:    
    108. High-throughput fluorescence detection using an integrated zone-plate array. Lab Chip. 2010 Apr 07; 10(7):852-6. Schonbrun E, Abate AR, Steinvurzel PE, Weitz DA, Crozier KB. PMID: 20300671.
      View in: PubMed   Mentions: 15     Fields:    
    109. Droplet microfluidics for fabrication of non-spherical particles. Macromol Rapid Commun. 2010 Jan 18; 31(2):108-18. Shum HC, Abate AR, Lee D, Studart AR, Wang B, Chen CH, Thiele J, Shah RK, Krummel A, Weitz DA. PMID: 21590882.
      View in: PubMed   Mentions: 20     Fields:    
    110. Multiple emulsions: Small 18/2009. Small. 2009 Sep 18; 5(18):na-na. A. R. Abate, D. A. Weitz. .
      View in: Publisher Site   Mentions:
    111. Magnetic Hydrogel Particles: Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure (Adv. Mater. 31/2009). Advanced Materials. 2009 Aug 21; 21(31):na-na. Chia-Hung Chen, Adam R. Abate, Daeyeon Lee, Eugene M. Terentjev, David A. Weitz. .
      View in: Publisher Site   Mentions:
    112. Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure. Advanced Materials. 2009 Aug 21; 21(31):3201-3204. Chia-Hung Chen, Adam R. Abate, Daeyeon Lee, Eugene M. Terentjev, David A. Weitz. .
      View in: Publisher Site   Mentions:
    113. A multi-color fast-switching microfluidic droplet dye laser. Lab Chip. 2009 Oct 07; 9(19):2767-71. Tang SK, Li Z, Abate AR, Agresti JJ, Weitz DA, Psaltis D, Whitesides GM. PMID: 19967111.
      View in: PubMed   Mentions: 21     Fields:    
    114. Beating Poisson encapsulation statistics using close-packed ordering. Lab Chip. 2009 Sep 21; 9(18):2628-31. Abate AR, Chen CH, Agresti JJ, Weitz DA. PMID: 19704976.
      View in: PubMed   Mentions: 37     Fields:    
    115. Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices. Lab Chip. 2009 Sep 21; 9(18):2625-7. Franke T, Abate AR, Weitz DA, Wixforth A. PMID: 19704975.
      View in: PubMed   Mentions: 48     Fields:    
    116. Janus particles templated from double emulsion droplets generated using microfluidics. Langmuir. 2009 Apr 21; 25(8):4320-3. Chen CH, Shah RK, Abate AR, Weitz DA. PMID: 19366216.
      View in: PubMed   Mentions: 7     Fields:    
    117. Valve-based flow focusing for drop formation. Applied Physics Letters. 2009 Jan 12; 94(2):023503. Adam R. Abate, Mark B. Romanowsky, Jeremy J. Agresti, David A. Weitz. .
      View in: Publisher Site   Mentions:
    118. Effective temperatures and activated dynamics for a two-dimensional air-driven granular system on two approaches to jamming. Phys Rev Lett. 2008 Dec 12; 101(24):245701. Abate AR, Durian DJ. PMID: 19113632.
      View in: PubMed   Mentions: 4     Fields:    
    119. Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability. Lab Chip. 2008 Dec; 8(12):2157-60. Abate AR, Krummel AT, Lee D, Marquez M, Holtze C, Weitz DA. PMID: 19023480.
      View in: PubMed   Mentions: 10     Fields:    
    120. Single-layer membrane valves for elastomeric microfluidic devices. Applied Physics Letters. 2008 Jun 16; 92(24):243509. A. R. Abate, D. A. Weitz. .
      View in: Publisher Site   Mentions:
    121. Glass coating for PDMS microfluidic channels by sol-gel methods. Lab Chip. 2008 Apr; 8(4):516-8. Abate AR, Lee D, Do T, Holtze C, Weitz DA. PMID: 18369504.
      View in: PubMed   Mentions: 35     Fields:    
    122. Spatially heterogeneous dynamics in a granular system near jamming. Chaos. 2007 Dec; 17(4):041107. Abate AR, Durian DJ. PMID: 18163762.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
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