Loading...

Edward Hsiao, MD, PhD

Title(s)Associate Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
Phone415-476-9732
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Johns Hopkins UniversityM.D.2001School of Medicine
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    EDUCATION/CLINICAL TRAINING
    MD: MD, PhD, Johns Hopkins Medical School, 2001
    Residency: Johns Hopkins Hospital, Baltimore, MD, Internal Medicine, 2001-2004
    Fellowship: UCSF, Division of Diabetes, Endocrinology and Metabolism, 2004-2007
    Board Certifications: Internal Medicine, 2004; Endocrinology and Metabolism, 2006

    ACADEMIC INTERESTS
    My research is driven by a desire to understand how major hormonal and regulatory pathways determine the specification, differentiation, and morphogenesis of mesenchymal tissues such as bone, cartilage, muscle, and fat. Mis-regulation of these pathways leads to significant medical diseases, including the inappropriate formation of mineralized tissues in atherosclerosis, heterotopic ossification, and cancer.

    My research focuses on understanding how these regulatory signals control normal and pathologic tissue formation as a way to identifying new therapeutic avenues for treating human diseases. Our laboratory takes a comprehensive approach to understanding hormone signaling in human diseases using synthetic biology approaches, mouse models, and human stem cell models.

    By combining multiple approaches with state-of-the art methods, our laboratory is working to develop a broader understanding of the biology underlying skeletal development, devise novel therapeutic approaches for treating human skeletal disorders and bone injuries, and examine how hormone signals affect important tissues such as fat, muscle, bone, cartilage, and blood vessels.

    CLINICAL INTERESTS:
    General Endocrinology with an interest in inherited skeletal diseases, including fibrous dysplasia of the bone (FD), McCune-Albright syndrome (MAS), and fibrodysplasia ossificans progressiva (FOP).

    Appointments: 415-353-2350
    Availability: General Endocrinology, 3rd Tuesday PM of each month

    Laboratory website: http://tiny.ucsf.edu/hsiaolab

    Collapse Research 
    Collapse Research Activities and Funding
    Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes Mellitus
    NIH/NIDDK UH3DK120004Sep 20, 2018 - Jul 31, 2023
    Role: Co-Principal Investigator
    Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes Mellitus
    NIH/NIDDK UG3DK120004Sep 20, 2018 - Jul 31, 2020
    Role: Co-Principal Investigator
    Pharmacologic modulation of innate immune dysfunction in heterotopic ossification
    NIH/NIAMS R01AR073015Sep 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Elucidating skeletal stem cell function using engineered 3D multicellular structures
    NIH/NIAMS R21AR072778Mar 13, 2018 - Jan 31, 2020
    Role: Principal Investigator
    Innate immune regulation of stem cells in bone formation
    NIH/NIAMS R01AR066735Sep 1, 2015 - Aug 31, 2020
    Role: Principal Investigator
    A New Regulator of Trabecular Bone Formation
    NIH/NIAMS R03AR060986Apr 1, 2011 - Jan 31, 2015
    Role: Principal Investigator
    Regulation of Bone Formation by G-protein Signaling
    NIH/NIAMS K08AR056299Jul 3, 2009 - Jun 30, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Websites
    Collapse Student Projects
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Virtual Interviews at Graduate Medical Education Training Programs: Determining Evidence-Based Best Practices. Acad Med. 2020 Dec 08. Huppert LA, Hsiao EC, Cho KC, Marquez C, Chaudhry RI, Frank J, Goglin SE, Hsu G, Kathpalia P, Khanna R, Kompala T, Rao MN, Bower BA, Trafas V, Santhosh L, Schwartz BS, Babik JM. PMID: 33298691.
      View in: PubMed   Mentions:    Fields:    
    2. A natural history study of fibrodysplasia ossificans progressiva (FOP): 12-month outcome results. Bone Reports. 2020 Oct 1; 13:100607. Robert J. Pignolo, Geneviève Baujat, Matthew A. Brown, Carmen De Cunto, Maja Di Rocco, Edward C. Hsiao, Richard Keen, Mona Al Mukaddam, Kim Hanh Le Quan Sang, Andrew Strahs, Rose Marino, Frederick S. Kaplan. .
      View in: Publisher Site   Mentions:
    3. Measuring outcomes in ultra-rare bone diseases: Methodology of the palovarotene fibrodysplasia ossificans progressiva clinical development programme. Bone Reports. 2020 Oct 1; 13:100609. Robert J. Pignolo, Geneviève Baujat, Matthew A. Brown, Carmen De Cunto, Maja Di Rocco, Edward C. Hsiao, Richard Keen, Mona Al Mukaddam, Andrew Strahs, Donna R. Grogan, Rose Marino, Frederick S. Kaplan. .
      View in: Publisher Site   Mentions:
    4. A global natural history study of Fibrodysplasia Ossificans Progressiva (FOP): 12-month outcomes. Endocrine Abstracts. 2020 Aug 21. Mona Al Mukaddam, Robert J. Pignolo, Geneviève Baujat, Matthew A Brown, Cunto Carmen De, Rocco Maja Di, Edward C. Hsiao, Richard Keen, Quan Sang Kim-Hanh Le, Andrew Strahs, Rose Marino, Frederick S Kaplan. .
      View in: Publisher Site   Mentions:
    5. Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva. Orphanet J Rare Dis. 2020 07 29; 15(1):193. Kou S, De Cunto C, Baujat G, Wentworth KL, Grogan DR, Brown MA, Di Rocco M, Keen R, Al Mukaddam M, le Quan Sang KH, Masharani U, Kaplan FS, Pignolo RJ, Hsiao EC. PMID: 32727600.
      View in: PubMed   Mentions:    Fields:    
    6. MON-348 Surgical Management of Bilateral Hip Fracture in a Patient with Fibrodysplasia Ossificans Progressiva Treated with Palovarotene. Journal of the Endocrine Society. 2020 May 8; 4(Suppl 1). Sukhmani Singh, Joseph Kidane, Kelly Lee Wentworth, Daria Motamedi, Saam Morshed, Edward Chiaming Hsiao. .
      View in: Publisher Site   Mentions:
    7. OR29-05 A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP): 12-Month Outcomes. Journal of the Endocrine Society. 2020 May 8; 4(Suppl 1). Mona Al Mukaddam, Robert J Pignolo, Geneviève Baujat, Matthew A Brown, Carmen De Cunto, Maja Di Rocco, Edward C Hsiao, Richard W Keen, Kim-Hanh Le Quan Sang, Andrew Strahs, Rose Marino, Frederick S Kaplan. .
      View in: Publisher Site   Mentions:
    8. MON-710 ACVR1 Activation in Primary and iPS-Derived Human Skeletal Muscle Stem Cells Impairs Myogenic Transcriptional Signature and Function. Journal of the Endocrine Society. 2020 May 8; 4(Supplement_1):mon-710-. Emilie Barruet, Steven Garcia, Stanley Tamaki, Blanca M Morales, Jake Wu, Tania Moody, Jason H Pomerantz, Edward Chiaming Hsiao. .
      View in: Publisher Site   Mentions:
    9. SUN-368 Wnt Inhibition Decreases Trabecular Bone in a Mouse Model of Fibrous Dysplasia. Journal of the Endocrine Society. 2020 May 8; 4(Suppl 1). Hsuan Lung, Kelly Wentworth, Tania Moody, Misun Kang, Sunita Ho, Edward Hsiao. .
      View in: Publisher Site   Mentions:
    10. SUN-344 Patients with Fibrodysplasia Ossificans Progressiva Have an Increased Prevalence of Cardiac Conduction Abnormalities. Journal of the Endocrine Society. 2020 May 8; 4(Suppl 1). Samuel Kou, Carmen DeCunto, Geneviève Baujat, Kelly Lee Wentworth, Donna Grogan, Matthew A Brown, Maja D Rocco, Richard Keen, Mona Al Mukaddam, Frederick S Kaplan, Robert J Pignolo, Edward Chiaming Hsiao. .
      View in: Publisher Site   Mentions:
    11. Surgical management of bilateral hip fractures in a patient with fibrodysplasia ossificans progressiva treated with the RAR-? agonist palovarotene: a case report. BMC Musculoskelet Disord. 2020 Apr 03; 21(1):204. Singh S, Kidane J, Wentworth KL, Motamedi D, Morshed S, Schober AE, Hsiao EC. PMID: 32245464.
      View in: PubMed   Mentions:    Fields:    
    12. Self-reported baseline phenotypes from the International Fibrodysplasia Ossificans Progressiva (FOP) Association Global Registry. Bone. 2020 05; 134:115274. Pignolo RJ, Cheung K, Kile S, Fitzpatrick MA, De Cunto C, Al Mukaddam M, Hsiao EC, Baujat G, Delai P, Eekhoff EMW, Di Rocco M, Grunwald Z, Haga N, Keen R, Levi B, Morhart R, Scott C, Sherman A, Zhang K, Kaplan FS. PMID: 32062004.
      View in: PubMed   Mentions: 1     Fields:    
    13. Advances in Models of Fibrous Dysplasia/McCune-Albright Syndrome. Front Endocrinol (Lausanne). 2019; 10:925. Lung H, Hsiao EC, Wentworth KL. PMID: 32038487.
      View in: PubMed   Mentions:
    14. Inflammation in Fibrodysplasia Ossificans Progressiva and Other Forms of Heterotopic Ossification. Curr Osteoporos Rep. 2019 12; 17(6):387-394. Matsuo K, Chavez RD, Barruet E, Hsiao EC. PMID: 31721068.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    15. Palovarotene inhibits the development of new heterotopic ossification in fibrodysplasia ossificans progressiva (FOP). Bone Abstracts. 2019 Jul 31. Frederick Kaplan, Edward C Hsiao, Genevieve Baujat, Richard Keen, Cunto Carmen De, Rocco Maja Di, Matthew A Brown, Mukaddam Mona M Al, Donna R Grogan, Robert J Pignolo. .
      View in: Publisher Site   Mentions:
    16. Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes. Orphanet J Rare Dis. 2019 May 23; 14(1):113. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Di Rocco M, Hsiao EC, Keen R, Al Mukaddam M, Sang KLQ, Wilson A, White B, Grogan DR, Kaplan FS. PMID: 31122250.
      View in: PubMed   Mentions:    Fields:    
    17. Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes. Orphanet J Rare Dis. 2019 05 03; 14(1):98. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Di Rocco M, Hsiao EC, Keen R, Al Mukaddam M, Sang KLQ, Wilson A, White B, Grogan DR, Kaplan FS. PMID: 31053156.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Effect of donor variation on osteogenesis and vasculogenesis in hydrogel cocultures. J Tissue Eng Regen Med. 2019 03; 13(3):433-445. Pennings I, van Dijk LA, van Huuksloot J, Fledderus JO, Schepers K, Braat AK, Hsiao EC, Barruet E, Morales BM, Verhaar MC, Rosenberg AJWP, Gawlitta D. PMID: 30650247.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. Therapeutic advances for blocking heterotopic ossification in fibrodysplasia ossificans progressiva. Br J Clin Pharmacol. 2019 06; 85(6):1180-1187. Wentworth KL, Masharani U, Hsiao EC. PMID: 30501012.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    20. NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification. JCI Insight. 2018 11 15; 3(22). Barruet E, Morales BM, Cain CJ, Ton AN, Wentworth KL, Chan TV, Moody TA, Haks MC, Ottenhoff TH, Hellman J, Nakamura MC, Hsiao EC. PMID: 30429363.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP). Br J Clin Pharmacol. 2019 06; 85(6):1199-1207. Hsiao EC, Di Rocco M, Cali A, Zasloff M, Al Mukaddam M, Pignolo RJ, Grunwald Z, Netelenbos C, Keen R, Baujat G, Brown MA, Cho TJ, De Cunto C, Delai P, Haga N, Morhart R, Scott C, Zhang K, Diecidue RJ, Friedman CS, Kaplan FS, Eekhoff EMW. PMID: 30281842.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Fibrodysplasia ossificans progressiva: a current review of imaging findings. Skeletal Radiol. 2018 Aug; 47(8):1043-1050. Bauer AH, Bonham J, Gutierrez L, Hsiao EC, Motamedi D. PMID: 29445932.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Utilizing 18F-fluoroethyltyrosine (FET) positron emission tomography (PET) to define suspected nonenhancing tumor for radiation therapy planning of glioblastoma. Pract Radiat Oncol. 2018 Jul - Aug; 8(4):230-238. Hayes AR, Jayamanne D, Hsiao E, Schembri GP, Bailey DL, Roach PJ, Khasraw M, Newey A, Wheeler HR, Back M. PMID: 29730279.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Clinical-pathological correlations in three patients with fibrodysplasia ossificans progressiva. Bone. 2018 04; 109:104-110. Wentworth KL, Bigay K, Chan TV, Ho JP, Morales BM, Connor J, Brooks E, Shahriar Salamat M, Sanchez HC, Wool G, Pignolo RJ, Kaplan FS, Hsiao EC. PMID: 29033382.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. The FOP Connection Registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva. Bone. 2018 04; 109:285-290. Mantick N, Bachman E, Baujat G, Brown M, Collins O, De Cunto C, Delai P, Eekhoff M, Zum Felde R, Grogan DR, Haga N, Hsiao E, Kantanie S, Kaplan F, Keen R, Milosevic J, Morhart R, Pignolo R, Qian X, di Rocco M, Scott C, Sherman A, Wallace M, Williams N, Zhang K, Bogard B. PMID: 28866367.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Sirtuin-3 Promotes Adipogenesis, Osteoclastogenesis, and Bone Loss in Aging Male Mice. Endocrinology. 2017 09 01; 158(9):2741-2753. Ho L, Wang L, Roth TM, Pan Y, Verdin EM, Hsiao EC, Nissenson RA. PMID: 28911171.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases. Bone. 2018 04; 109:276-280. Kaplan FS, Andolina JR, Adamson PC, Teachey DT, Finklestein JZ, Ebb DH, Whitehead B, Jacobs B, Siegel DM, Keen R, Hsiao E, Pignolo RJ. PMID: 28736245.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    28. Application of human induced pluripotent stem cells to model fibrodysplasia ossificans progressiva. Bone. 2018 04; 109:162-167. Barruet E, Hsiao EC. PMID: 28716551.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Fibrodysplasia ossificans progressiva: baseline characteristics of 101 subjects participating in a global, longitudinal, natural history study. Bone Abstracts. 2017 Jul 11. Frederick S Kaplan, Edward C Hsiao, Genevieve Baujat, Matthew A Brown, Cunto Carmen De, Rocco Maja Di, Richard Keen, Makkadam Mona Al, Donna R Grogan, Robert J Pignolo. .
      View in: Publisher Site   Mentions:
    30. International physician survey on management of FOP: a modified Delphi study. Orphanet J Rare Dis. 2017 06 12; 12(1):110. Di Rocco M, Baujat G, Bertamino M, Brown M, De Cunto CL, Delai PLR, Eekhoff EMW, Haga N, Hsiao E, Keen R, Morhart R, Pignolo RJ, Kaplan FS. PMID: 28606101.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Fluorescent tagged episomals for stoichiometric induced pluripotent stem cell reprogramming. Stem Cell Res Ther. 2017 06 05; 8(1):132. Schmitt CE, Morales BM, Schmitz EMH, Hawkins JS, Lizama CO, Zape JP, Hsiao EC, Zovein AC. PMID: 28583172.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance. Theranostics. 2017; 7(5):1149-1158. Chan DL, Pavlakis N, Schembri GP, Bernard EJ, Hsiao E, Hayes A, Barnes T, Diakos C, Khasraw M, Samra J, Eslick E, Roach PJ, Engel A, Clarke SJ, Bailey DL. PMID: 28435454.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    33. EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells. Stem Cell Reports. 2017 03 14; 8(3):529-537. Niethamer TK, Larson AR, O'Neill AK, Bershteyn M, Hsiao EC, Klein OD, Pomerantz JH, Bush JO. PMID: 28238796.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. The Rare Bone Disease Working Group: report from the 2016 American Society for Bone and Mineral Research Annual Meeting. Bone. 2017 Sep; 102:80-84. Drake MT, Collins MT, Hsiao EC. PMID: 28115283.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):13057-13062. Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S. PMID: 27794120.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    36. Gs/Gi Regulation of Bone Cell Differentiation: Review and Insights from Engineered Receptors. Horm Metab Res. 2016 Nov; 48(11):689-699. Hsiao EC, Millard SM, Nissenson RA. PMID: 27643449.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    37. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. Stem Cell Res Ther. 2016 08 17; 7(1):115. Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. PMID: 27530160.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    38. A Novel T55A Variant of Gs a Associated with Impaired cAMP Production, Bone Fragility, and Osteolysis. Case Rep Endocrinol. 2016; 2016:2691385. Wentworth K, Hsing A, Urrutia A, Zhu Y, Horvai AE, Bastepe M, Hsiao EC. PMID: 27579188.
      View in: PubMed   Mentions:
    39. Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization. Bone Rep. 2016 Dec; 5:86-95. Cain CJ, Gaborit N, Lwin W, Barruet E, Ho S, Bonnard C, Hamamy H, Shboul M, Reversade B, Kayserili H, Bruneau BG, Hsiao EC. PMID: 27453922.
      View in: PubMed   Mentions:
    40. Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. Endocrinology. 2016 Apr; 157(4):1481-94. Cain CJ, Valencia JT, Ho S, Jordan K, Mattingly A, Morales BM, Hsiao EC. PMID: 26901092.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. Using Human Induced Pluripotent Stem Cells to Model Skeletal Diseases. Methods Mol Biol. 2016; 1353:101-18. Barruet E, Hsiao EC. PMID: 25549831.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    42. A Case of Hypercalcemia and Overexpression of CYP27B1 in Skeletal Muscle Lesions in a Patient with HIV Infection After Cosmetic Injections with Polymethylmethacrylate (PMMA) for Wasting. Calcif Tissue Int. 2015 Dec; 97(6):634-9. Hindi SM, Wang Y, Jones KD, Nussbaum JC, Chang Y, Masharani U, Bikle D, Shoback DM, Hsiao EC. PMID: 26253396.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Maternal Hypercalcemia Due to Failure of 1,25-Dihydroxyvitamin-D3 Catabolism in a Patient With CYP24A1 Mutations. J Clin Endocrinol Metab. 2015 Aug; 100(8):2832-6. Shah AD, Hsiao EC, O'Donnell B, Salmeen K, Nussbaum R, Krebs M, Baumgartner-Parzer S, Kaufmann M, Jones G, Bikle DD, Wang Y, Mathew AS, Shoback D, Block-Kurbisch I. PMID: 26097993.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    44. Loss of Gi G-Protein-Coupled Receptor Signaling in Osteoblasts Accelerates Bone Fracture Healing. J Bone Miner Res. 2015 Oct; 30(10):1896-904. Wang L, Hsiao EC, Lieu S, Scott M, O'Carroll D, Urrutia A, Conklin BR, Colnot C, Nissenson RA. PMID: 25917236.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    45. Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man. Skeletal Radiol. 2015 Sep; 44(9):1359-64. Hong CW, Hsiao EC, Horvai AE, Link TM. PMID: 25771734.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts. Exp Cell Res. 2015 May 01; 333(2):289-302. Wattanachanya L, Wang L, Millard SM, Lu WD, O'Carroll D, Hsiao EC, Conklin BR, Nissenson RA. PMID: 25704759.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    47. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015 Mar; 18(3):423-34. Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L. PMID: 25622143.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    48. Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia. PLoS One. 2014; 9(5):e94989. Akil O, Hall-Glenn F, Chang J, Li A, Chang W, Lustig LR, Alliston T, Hsiao EC. PMID: 24788917.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    49. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. J Bone Miner Res. 2014 Apr; 29(4):911-21. Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM. PMID: 24014458.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    50. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 2014 Mar 06; 507(7490):99-103. Bershteyn M, Hayashi Y, Desachy G, Hsiao EC, Sami S, Tsang KM, Weiss LA, Kriegstein AR, Yamanaka S, Wynshaw-Boris A. PMID: 24413397.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    51. Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis. 2013 Dec 09; 8:190. Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC. PMID: 24321451.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    52. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 2013 Sep 05; 13(3):285-99. Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. PMID: 23850243.
      View in: PubMed   Mentions: 212     Fields:    Translation:HumansAnimalsCells
    53. AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to ß-adrenergic-induced cardiac hypertrophy. PLoS One. 2013; 8(4):e62705. Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR. PMID: 23658642.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    54. Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice. Blood. 2012 Oct 25; 120(17):3425-35. Schepers K, Hsiao EC, Garg T, Scott MJ, Passegué E. PMID: 22859604.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    55. Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor. Calcif Tissue Int. 2011 Jul; 89(1):10-20. Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC. PMID: 21526395.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    56. Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice. Stem Cell Res Ther. 2011 Mar 04; 2(2):11. Hsiao EC, Nguyen TD, Ng JK, Scott MJ, Chang WC, Zahed H, Conklin BR. PMID: 21375737.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    57. Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ Res. 2010 Aug 06; 107(3):340-7. van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D. PMID: 20558827.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    58. Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. J Bone Miner Res. 2010 Mar; 25(3):584-93. Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR. PMID: 20200944.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    59. Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation. Mol Endocrinol. 2010 Mar; 24(3):621-31. Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA. PMID: 20150184.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    60. Engineering GPCR signaling pathways with RASSLs. Nat Methods. 2008 Aug; 5(8):673-8. Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. PMID: 18668035.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    61. Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter. PLoS One. 2008 Jul 02; 3(7):e2532. Hsiao EC, Yoshinaga Y, Nguyen TD, Musone SL, Kim JE, Swinton P, Espineda I, Manalac C, deJong PJ, Conklin BR. PMID: 18596956.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    62. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell. 2008 Mar 06; 2(3):219-29. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. PMID: 18371447.
      View in: PubMed   Mentions: 228     Fields:    Translation:HumansAnimalsCells
    63. Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1209-14. Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA. PMID: 18212126.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    64. Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor. PLoS One. 2007 Dec 19; 2(12):e1317. Chang WC, Ng JK, Nguyen T, Pellissier L, Claeysen S, Hsiao EC, Conklin BR. PMID: 18338032.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    65. Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10894-9. Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D. PMID: 17576928.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    66. A Series of RASSLs Activated by a Single Agonist. The FASEB Journal. 2006 Mar 1; 20(4):a249-a249. Peter Chang, Edward Hsiao, Alex C Zambon, Bruce R Conklin. .
      View in: Publisher Site   Mentions:
    67. Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms. J Surg Res. 2006 Jan; 130(1):45-51. Zimmers TA, Jin X, Hsiao EC, Perez EA, Pierce RH, Chavin KD, Koniaris LG. PMID: 16154591.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    68. Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury. Shock. 2005 Jun; 23(6):543-8. Zimmers TA, Jin X, Hsiao EC, McGrath SA, Esquela AF, Koniaris LG. PMID: 15897808.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    69. An unusual development. Am J Med. 2005 Jun; 118(6):609-11. Hsiao E, Charles R, Magid C, Nivatpumin P, Wiener CM. PMID: 15922691.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    70. Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling. J Clin Endocrinol Metab. 2005 Jul; 90(7):4350-6. Nakakura EK, Sriuranpong VR, Kunnimalaiyaan M, Hsiao EC, Schuebel KE, Borges MW, Jin N, Collins BJ, Nelkin BD, Chen H, Ball DW. PMID: 15870121.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    71. Diagnostic I-123 scintigraphy to assess potential breast uptake of I-131 before radioiodine therapy in a postpartum woman with thyroid cancer. Clin Nucl Med. 2004 Aug; 29(8):498-501. Hsiao E, Huynh T, Mansberg R, Bautovich G, Roach P. PMID: 15249829.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    72. Cases from the Osler medical service at Johns Hopkins University. Am J Med. 2004 Apr 01; 116(7):490-2. Maruthur NM, Hsiao EC, Lee J, Nivatpumin P. PMID: 15047040.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Transient absence of hepatic uptake on gallium-67 scintigraphy following fludarabine therapy. Clin Nucl Med. 2004 Apr; 29(4):275-6. Huynh T, Mansberg R, Hsiao E, Coyle L, Roach P. PMID: 15096981.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    74. Pericarditis associated with cryptococcal meningitis on Ga-67 scintigraphy. Clin Nucl Med. 2004 Feb; 29(2):119-20. Hsiao E, Mansberg R, Huynh T, Roach P. PMID: 14734914.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    75. Cytokine-responsive gene-2/IFN-inducible protein-10 expression in multiple models of liver and bile duct injury suggests a role in tissue regeneration. J Immunol. 2001 Jul 01; 167(1):399-406. Koniaris LG, Zimmers-Koniaris T, Hsiao EC, Chavin K, Sitzmann JV, Farber JM. PMID: 11418676.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    76. Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury. Mol Cell Biol. 2000 May; 20(10):3742-51. Hsiao EC, Koniaris LG, Zimmers-Koniaris T, Sebald SM, Huynh TV, Lee SJ. PMID: 10779363.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    77. Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements. RNA. 1996 Oct; 2(10):969-81. Hertel KJ, Lynch KW, Hsiao EC, Liu EH, Maniatis T. PMID: 8849774.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    Edward's Networks
    Concepts (413)
    Derived automatically from this person's publications.
    _
    Co-Authors (64)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _