Edward Hsiao, MD, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #901G
San Francisco CA 94143
Phone415-476-9732
ORCID ORCID Icon0000-0001-8924-106X Additional info
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    Collapse Biography 
    Collapse Education and Training
    Johns Hopkins UniversityM.D.2001School of Medicine
    University of California, San Francisco, CA2019Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    EDUCATION/CLINICAL TRAINING
    MD: MD, PhD, Johns Hopkins Medical School, 2001
    Residency: Johns Hopkins Hospital, Baltimore, MD, Internal Medicine, 2001-2004
    Fellowship: UCSF, Division of Diabetes, Endocrinology and Metabolism, 2004-2007
    Board Certifications: Internal Medicine, 2004; Endocrinology and Metabolism, 2006

    ACADEMIC INTERESTS
    My research is driven by a desire to understand how major hormonal and regulatory pathways determine the specification, differentiation, and morphogenesis of mesenchymal tissues such as bone, cartilage, muscle, and fat. Mis-regulation of these pathways leads to significant medical diseases, including the inappropriate formation of mineralized tissues in atherosclerosis, heterotopic ossification, and cancer.

    My research focuses on understanding how these regulatory signals control normal and pathologic tissue formation as a way to identifying new therapeutic avenues for treating human diseases. Our laboratory takes a comprehensive approach to understanding hormone signaling in human diseases using synthetic biology approaches, mouse models, and human stem cell models.

    By combining multiple approaches with state-of-the art methods, our laboratory is working to develop a broader understanding of the biology underlying skeletal development, devise novel therapeutic approaches for treating human skeletal disorders and bone injuries, and examine how hormone signals affect important tissues such as fat, muscle, bone, cartilage, and blood vessels.

    CLINICAL INTERESTS:
    General Endocrinology with an interest in inherited skeletal diseases, including fibrous dysplasia of the bone (FD), McCune-Albright syndrome (MAS), and fibrodysplasia ossificans progressiva (FOP).

    Appointments: 415-353-2350
    Availability: General Endocrinology, 3rd Tuesday PM of each month

    Laboratory website: https://hsiaolab.ucsf.edu

    Collapse Research 
    Collapse Research Activities and Funding
    Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes Mellitus
    NIH UH3DK120004Sep 20, 2018 - Jul 31, 2023
    Role: Co-Principal Investigator
    Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes Mellitus
    NIH UG3DK120004Sep 20, 2018 - Jul 31, 2020
    Role: Co-Principal Investigator
    Pharmacologic modulation of innate immune dysfunction in heterotopic ossification
    NIH R01AR073015Sep 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Elucidating skeletal stem cell function using engineered 3D multicellular structures
    NIH R21AR072778Mar 13, 2018 - Jan 31, 2020
    Role: Principal Investigator
    Innate immune regulation of stem cells in bone formation
    NIH R01AR066735Sep 1, 2015 - Aug 31, 2021
    Role: Principal Investigator
    A New Regulator of Trabecular Bone Formation
    NIH R03AR060986Apr 1, 2011 - Jan 31, 2015
    Role: Principal Investigator
    Regulation of Bone Formation by G-protein Signaling
    NIH K08AR056299Jul 3, 2009 - Jun 30, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Collaboration Interests

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immunologic Aspects in Fibrodysplasia Ossificans Progressiva. Biomolecules. 2024 Mar 16; 14(3). Diolintzi A, Pervin MS, Hsiao EC. PMID: 38540775; PMCID: PMC10967946.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Intersections of Fibrodysplasia Ossificans Progressiva and Traumatic Heterotopic Ossification. Biomolecules. 2024 Mar 14; 14(3). Juan C, Bancroft AC, Choi JH, Nunez JH, Pagani CA, Lin YS, Hsiao EC, Levi B. PMID: 38540768; PMCID: PMC10968060.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. MMP-9 deficiency confers resilience in Fibrodysplasia Ossificans Progressiva in a man and mice. J Bone Miner Res. 2024 Feb 16. Lounev V, Groppe JC, Brewer N, Wentworth KL, Smith V, Xu M, Schomburg L, Bhargava P, Al Mukaddam M, Hsiao EC, Shore EM, Pignolo RJ, Kaplan FS. PMID: 38477818.
      View in: PubMed   Mentions:    Fields:    
    4. Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone. JBMR Plus. 2024 May; 8(5):ziae011. Lung H, Wentworth KL, Moody T, Zamarioli A, Ram A, Ganesh G, Kang M, Ho S, Hsiao EC. PMID: 38577521; PMCID: PMC10994528.
      View in: PubMed   Mentions:
    5. Overall survival with [177Lu]Lu-PSMA-617 versus cabazitaxel in metastatic castration-resistant prostate cancer (TheraP): secondary outcomes of a randomised, open-label, phase 2 trial. Lancet Oncol. 2024 Jan; 25(1):99-107. Hofman MS, Emmett L, Sandhu S, Iravani A, Buteau JP, Joshua AM, Goh JC, Pattison DA, Tan TH, Kirkwood ID, Ng S, Francis RJ, Gedye C, Rutherford NK, Weickhardt A, Scott AM, Lee ST, Kwan EM, Azad AA, Ramdave S, Redfern AD, Macdonald W, Guminski A, Hsiao E, Chua W, Lin P, Zhang AY, Stockler MR, Williams SG, Martin AJ, Davis ID, TheraP Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials . PMID: 38043558.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    6. Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressiva. BMC Med Res Methodol. 2023 11 13; 23(1):269. Pignolo RJ, Al Mukaddam M, Baujat G, Brown MA, De Cunto C, Hsiao EC, Keen R, Le Quan Sang KH, Grogan DR, Marino R, Strahs AR, Kaplan FS. PMID: 37957586; PMCID: PMC10642058.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Frontal bone loss following coronal brow lift: A mimicker of head variant linear morphea. JAAD Case Rep. 2023 Nov; 41:4-6. Kazmi M, Zhang WR, Hsiao E, Gross A, Grouse K, Link TM, Tetzlaff M, Theodosopoulos P, Haemel A. PMID: 37842147; PMCID: PMC10568232.
      View in: PubMed   Mentions:
    8. Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages. Nat Commun. 2023 07 03; 14(1):3902. Groeger M, Matsuo K, Heidary Arash E, Pereira A, Le Guillou D, Pino C, Telles-Silva KA, Maher JJ, Hsiao EC, Willenbring H. PMID: 37400454; PMCID: PMC10318012.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. EML4::ALK fusions in complex lymphatic malformations. Pediatr Blood Cancer. 2023 Jun 28; e30516. Apsel Winger B, Devine WP, Hsiao EC, Zapala M, Van Ziffle J, Gupta N, Frieden IJ, Shimano KA. PMID: 37377128.
      View in: PubMed   Mentions:    Fields:    
    10. A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy. Calcif Tissue Int. 2023 08; 113(2):246-253. Niu I, Hsiao EC, Wustrack R, Wysolmerski JJ, Dann P, Masharani U. PMID: 37358786; PMCID: PMC10372127.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit. Osteoporos Int. 2023 Aug; 34(8):1301-1310. Chandran M, Alves I, Carpenter T, Davis M, Hsiao EC, Petryk A, Semler JO, Sleiman M. PMID: 37294334; PMCID: PMC10382343.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. CO32 Heterotopic Ossification in Palovarotene-Treated and Untreated Individuals with Fibrodysplasia Ossificans Progressiva: Matched and Weighted Analyses. Value in Health. 2023 Jun 1; 26(6):s20. Mukaddam MM, Baujat BG, Cheung CA, De Cunto DC, Hsiao HE, Keen KR, Marden MJ, Signorovitch SJ, Boing BE, Marino MR, Strahs SA, Pignolo PR. .
      View in: Publisher Site   Mentions:
    13. Most Fractures Treated Nonoperatively in Individuals With Fibrodysplasia Ossificans Progressiva Heal With a Paucity of Flareups, Heterotopic Ossification, and Loss of Mobility. Clin Orthop Relat Res. 2023 12 01; 481(12):2447-2458. Lindborg CM, Al Mukaddam M, Baujat G, Cho TJ, De Cunto CL, Delai PLR, Eekhoff EMW, Haga N, Hsiao EC, Morhart R, de Ruiter R, Scott C, Seemann P, Szczepanek M, Tabarkiewicz J, Pignolo RJ, Kaplan FS. PMID: 37156007; PMCID: PMC10642855.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Human iPSC-Derived Proinflammatory Macrophages cause Insulin Resistance in an Isogenic White Adipose Tissue Microphysiological System. Small. 2023 08; 19(34):e2203725. Qi L, Matsuo K, Pereira A, Lee YT, Zhong F, He Y, Zushin PH, Gröger M, Sharma A, Willenbring H, Hsiao EC, Stahl A. PMID: 37104853; PMCID: PMC10502939.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    15. A follow-up report on the published paper Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva. Orphanet J Rare Dis. 2023 03 20; 18(1):61. Wallace H, Lee RH, Hsiao EC. PMID: 36941608; PMCID: PMC10025781.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    16. Reduction of New Heterotopic Ossification (HO) in the Open-Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP). J Bone Miner Res. 2023 03; 38(3):381-394. Pignolo RJ, Hsiao EC, Al Mukaddam M, Baujat G, Berglund SK, Brown MA, Cheung AM, De Cunto C, Delai P, Haga N, Kannu P, Keen R, Le Quan Sang KH, Mancilla EE, Marino R, Strahs A, Kaplan FS. PMID: 36583535.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    17. The effects of palovarotene in patients with fibrodysplasia ossificans progressiva: a plain language summary. Future Rare Diseases. 2023 Jan 18; 3(1):frd33. Pignolo PR, Hsiao HE, Mukaddam MM, Baujat BG, Berglund BS, Brown BM, Cheung CA, De Cunto DC, Delai DP, Haga HN, Kannu KP, Keen KR, Le Quan Sang LK, Mancilla ME, Marino MR, Strahs SA, Kaplan KF. .
      View in: Publisher Site   Mentions:
    18. Functional Testing of Bone Morphogenetic Protein (BMP) Pathway Variants Identified on Whole-Exome Sequencing in a Patient with Delayed-Onset Fibrodysplasia Ossificans Progressiva (FOP) Using ACVR1R206H -Specific Human Cellular and Zebrafish Models. J Bone Miner Res. 2022 11; 37(11):2058-2076. Wentworth KL, Lalonde RL, Groppe JC, Brewer N, Moody T, Hansberry S, Taylor KE, Shore EM, Kaplan FS, Pignolo RJ, Yelick PC, Hsiao EC. PMID: 36153796; PMCID: PMC9950781.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    19. PSAT208 A Case of Hypercalcemia From PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy. Journal of the Endocrine Society. 2022 Nov 1; 6(Suppl 1):a212-a213. Niu NI, Hsiao HE, Wustrack WR, Wysolmerski WJ, Dann DP, Masharani MU. .
      View in: Publisher Site   Mentions:
    20. Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery. Nat Commun. 2022 10 19; 13(1):6175. Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong J, Chun H, Shore EM, Kaplan FS, Gao G, Shim JH. PMID: 36258013; PMCID: PMC9579182.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    21. The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study. Genet Med. 2022 Dec; 24(12):2422-2433. Pignolo RJ, Baujat G, Brown MA, De Cunto C, Hsiao EC, Keen R, Al Mukaddam M, Le Quan Sang KH, Wilson A, Marino R, Strahs A, Kaplan FS. PMID: 36152026.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Identification of Risk Factors in the Development of Heterotopic Ossification After Primary Total Hip Arthroplasty. J Clin Endocrinol Metab. 2022 08 18; 107(9):e3944-e3952. Singh S, Morshed S, Motamedi D, Kidane J, Paul A, Hsiao EC, Wentworth KL. PMID: 35451005; PMCID: PMC9387692.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial. J Bone Miner Res. 2022 10; 37(10):1891-1902. Pignolo RJ, Baujat G, Hsiao EC, Keen R, Wilson A, Packman J, Strahs AL, Grogan DR, Kaplan FS. PMID: 35854638.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    24. Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles. Hum Gene Ther. 2022 08; 33(15-16):782-788. Eekhoff EMW, de Ruiter RD, Smilde BJ, Schoenmaker T, de Vries TJ, Netelenbos C, Hsiao EC, Scott C, Haga N, Grunwald Z, De Cunto CL, di Rocco M, Delai PLR, Diecidue RJ, Madhuri V, Cho TJ, Morhart R, Friedman CS, Zasloff M, Pals G, Shim JH, Gao G, Kaplan F, Pignolo RJ, Micha D. PMID: 35502479; PMCID: PMC9419966.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans. Pain. 2023 01 01; 164(1):43-58. Yu X, Ton AN, Niu Z, Morales BM, Chen J, Braz J, Lai MH, Barruet E, Liu H, Cheung K, Ali S, Chan T, Bigay K, Ho J, Nikolli I, Hansberry S, Wentworth K, Kriegstein A, Basbaum A, Hsiao EC. PMID: 35442931; PMCID: PMC9582048.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Social and clinical impact of COVID-19 on patients with fibrodysplasia ossificans progressiva. Orphanet J Rare Dis. 2022 03 04; 17(1):107. Kou S, Kile S, Kambampati SS, Brady EC, Wallace H, De Sousa CM, Cheung K, Dickey L, Wentworth KL, Hsiao EC. PMID: 35246171; PMCID: PMC8894823.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    27. Corrigendum to "ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages" [Bone. 153 2021 Dec; 116129. doi:10.1016/j.bone.2021.116129. Epub 2021 Jul 24. PMID: 34311122]. Bone. 2022 May; 158:116325. Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC. PMID: 35241401.
      View in: PubMed   Mentions:    Fields:    
    28. The Clinical Significance of Small Vessel Vasculitis on Temporal Artery Biopsies. J Neuroophthalmol. 2022 06 01; 42(2):212-217. Quigley J, Sammel AM, Laurent R, Brewer J, Hsiao E, Schembri G, Fraser CL. PMID: 35195542.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. POSC373 Use of Aids, Assistive Devices and Adaptations by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): 36-Month Results from a Global Natural History Study. Value in Health. 2022 Jan 1; 25(1):s245-s246. Mukaddam MM, Baujat BG, Houchard HA, Hsiao HE, Keen KR, Marino MR, Pignolo PR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    30. A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programs. Med Educ Online. 2021 Dec; 26(1):1946237. Huppert LA, Hsu G, Elnachef N, Flint L, Frank JA, Gensler LS, Hsiao EC, Khanna RR, Qasim A, Schwartz BS, Widera E, Zapata C, Babik JM. PMID: 34187346; PMCID: PMC8253192.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    31. Modeling the ACVR1R206H mutation in human skeletal muscle stem cells. Elife. 2021 11 10; 10. Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, Pomerantz JH, Hsiao EC. PMID: 34755602; PMCID: PMC8691832.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    32. Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop. Front Endocrinol (Lausanne). 2021; 12:732728. de Ruiter RD, Smilde BJ, Pals G, Bravenboer N, Knaus P, Schoenmaker T, Botman E, Sánchez-Duffhues G, Pacifici M, Pignolo RJ, Shore EM, van Egmond M, Van Oosterwyck H, Kaplan FS, Hsiao EC, Yu PB, Bocciardi R, De Cunto CL, Longo Ribeiro Delai P, de Vries TJ, Hilderbrandt S, Jaspers RT, Keen R, Koolwijk P, Morhart R, Netelenbos JC, Rustemeyer T, Scott C, Stockklausner C, Ten Dijke P, Triffit J, Ventura F, Ravazzolo R, Micha D, Eekhoff EMW. PMID: 34858325; PMCID: PMC8631510.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    33. Social and Clinical Impact of COVID-19 on Patients with Fibrodysplasia Ossificans Progressiva. Res Sq. 2021 Sep 16. Kou S, Kile S, Kambampati SS, Brady EC, Wallace H, De Sousa CM, Cheung K, Dickey L, Wentworth KL, Hsiao E. PMID: 34545360; PMCID: PMC8452110.
      View in: PubMed   Mentions:
    34. Prevalence of fibrodysplasia ossificans progressiva (FOP) in the United States: estimate from three treatment centers and a patient organization. Orphanet J Rare Dis. 2021 08 05; 16(1):350. Pignolo RJ, Hsiao EC, Baujat G, Lapidus D, Sherman A, Kaplan FS. PMID: 34353327; PMCID: PMC8340531.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    35. Whole-body Computed Tomography Versus Dual Energy X‑ray Absorptiometry for Assessing Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva. Calcif Tissue Int. 2021 12; 109(6):615-625. Warner SE, Kaplan FS, Pignolo RJ, Smith SE, Hsiao EC, De Cunto C, Di Rocco M, Harnett K, Grogan D, Genant HK. PMID: 34331548; PMCID: PMC8531122.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    36. ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages. Bone. 2021 12; 153:116129. Matsuo K, Lepinski A, Chavez RD, Barruet E, Pereira A, Moody TA, Ton AN, Sharma A, Hellman J, Tomoda K, Nakamura MC, Hsiao EC. PMID: 34311122; PMCID: PMC8803261.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    37. Re-defining the role of surgery in the management of patients with oligometastatic stage IV melanoma in the era of effective systemic therapies. Eur J Cancer. 2021 08; 153:8-15. Ch'ng S, Uyulmaz S, Carlino MS, Pennington TE, Shannon KF, Rtshiladze M, Stretch JR, Nieweg OE, Varey AHR, Hsiao E, Kapoor R, Pires da Silva I, Lo SN, Spillane AJ, Scolyer RA, Long GV, Hong AM, Saw RPM, Thompson JF, Menzies AM. PMID: 34126335.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Off-on-off-on use of imatinib in three children with fibrodysplasia ossificans progressiva. Bone. 2021 09; 150:116016. Kaplan FS, Teachey DT, Andolina JR, Siegel DM, Mancilla EE, Hsiao EC, Al Mukaddam M, Rocke DM, Pignolo RJ. PMID: 34022457.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Global Wnt Inhibition With a Porcupine Inhibitor Decreases Established Trabecular Bone in a Mouse Model of Fibrous Dysplasia. Journal of the Endocrine Society. 2021 May 3; 5(Suppl 1):a234-a234. Lung LH, Moody MT, Wentworth WK, Kang KM, Ho HS, Hsiao HE. .
      View in: Publisher Site   Mentions:
    40. [177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial. Lancet. 2021 02 27; 397(10276):797-804. Hofman MS, Emmett L, Sandhu S, Iravani A, Joshua AM, Goh JC, Pattison DA, Tan TH, Kirkwood ID, Ng S, Francis RJ, Gedye C, Rutherford NK, Weickhardt A, Scott AM, Lee ST, Kwan EM, Azad AA, Ramdave S, Redfern AD, Macdonald W, Guminski A, Hsiao E, Chua W, Lin P, Zhang AY, McJannett MM, Stockler MR, Violet JA, Williams SG, Martin AJ, Davis ID, TheraP Trial Investigators and the Australian and New Zealand Urogenital and Prostate Cancer Trials . PMID: 33581798.
      View in: PubMed   Mentions: 265     Fields:    Translation:HumansCTClinical Trials
    41. Cardiopulmonary and Neurologic Dysfunctions in Fibrodysplasia Ossificans Progressiva. Biomedicines. 2021 Feb 05; 9(2). Khan F, Yu X, Hsiao EC. PMID: 33562570; PMCID: PMC7915901.
      View in: PubMed   Mentions: 6  
    42. A Global Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP): 12-Month Outcomes. Osteologie/Osteology. 2021 Feb 1; 30(01):73-73. Mukaddam MM, Stockklausner SC, Pignolo PR, Baujat BG, Brown BM, De Cunto DC, Di Rocco DM, Hsiao HE, Keen KR, Le Quan Sang LK, Strahs SA, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    43. Use of Assistive Devices and Adaptations by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology. 2021 Feb 1; 30(01):75-75. Hsiao HE, Semler SJ, Mukaddam MM, Baujat BG, De Cunto DC, Keen KR, Pignolo PR, Harnett HK, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    44. Medications Used by Individuals with Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology. 2021 Feb 1; 30(01):73-74. Keen KR, Stockklausner SC, Mukaddam MM, Baujat BG, De Cunto DC, Hsiao HE, Pignolo PR, Harnett HK, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    45. Longitudinal and Flare-Up-Specific Biomarkers in Fibrodysplasia Ossificans Progressiva (FOP): Data from a Global Natural History Study. Osteologie/Osteology. 2021 Feb 1; 30(01):75-76. Pignolo PR, Semler SJ, Mukaddam MM, Baujat BG, De Cunto DC, Hsiao HE, Keen KR, Harnett HK, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    46. Virtual Interviews at Graduate Medical Education Training Programs: Determining Evidence-Based Best Practices. Acad Med. 2021 08 01; 96(8):1137-1145. Huppert LA, Hsiao EC, Cho KC, Marquez C, Chaudhry RI, Frank J, Goglin SE, Hsu G, Kathpalia P, Khanna R, Kompala T, Rao MN, Bower BA, Trafas V, Santhosh L, Schwartz BS, Babik JM. PMID: 33298691.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    47. A natural history study of fibrodysplasia ossificans progressiva (FOP): 12-month outcome results. Bone Reports. 2020 Oct 1; 13:100607. Pignolo PR, Baujat BG, Brown BM, De Cunto DC, Di Rocco DM, Hsiao HE, Keen KR, Mukaddam MM, Le Quan Sang LK, Strahs SA, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    48. Measuring outcomes in ultra-rare bone diseases: Methodology of the palovarotene fibrodysplasia ossificans progressiva clinical development programme. Bone Reports. 2020 Oct 1; 13:100609. Pignolo PR, Baujat BG, Brown BM, De Cunto DC, Di Rocco DM, Hsiao HE, Keen KR, Mukaddam MM, Strahs SA, Grogan GD, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    49. A global natural history study of Fibrodysplasia Ossificans Progressiva (FOP): 12-month outcomes. Endocrine Abstracts. 2020 Aug 21. Mukaddam MM, Pignolo PR, Baujat BG, Brown BM, De DC, Di DR, Hsiao HE, Keen KR, Le LQ, Strahs SA, Marino MR, Kaplan KF. .
      View in: Publisher Site   Mentions:
    50. Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva. Orphanet J Rare Dis. 2020 07 29; 15(1):193. Kou S, De Cunto C, Baujat G, Wentworth KL, Grogan DR, Brown MA, Di Rocco M, Keen R, Al Mukaddam M, le Quan Sang KH, Masharani U, Kaplan FS, Pignolo RJ, Hsiao EC. PMID: 32727600; PMCID: PMC7389682.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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    117. Cases from the Osler medical service at Johns Hopkins University. Am J Med. 2004 Apr 01; 116(7):490-2. Maruthur NM, Hsiao EC, Lee J, Nivatpumin P. PMID: 15047040.
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    118. Transient absence of hepatic uptake on gallium-67 scintigraphy following fludarabine therapy. Clin Nucl Med. 2004 Apr; 29(4):275-6. Huynh T, Mansberg R, Hsiao E, Coyle L, Roach P. PMID: 15096981.
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    119. Pericarditis associated with cryptococcal meningitis on Ga-67 scintigraphy. Clin Nucl Med. 2004 Feb; 29(2):119-20. Hsiao E, Mansberg R, Huynh T, Roach P. PMID: 14734914.
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    120. Cytokine-responsive gene-2/IFN-inducible protein-10 expression in multiple models of liver and bile duct injury suggests a role in tissue regeneration. J Immunol. 2001 Jul 01; 167(1):399-406. Koniaris LG, Zimmers-Koniaris T, Hsiao EC, Chavin K, Sitzmann JV, Farber JM. PMID: 11418676.
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    121. Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury. Mol Cell Biol. 2000 May; 20(10):3742-51. Hsiao EC, Koniaris LG, Zimmers-Koniaris T, Sebald SM, Huynh TV, Lee SJ. PMID: 10779363; PMCID: PMC85678.
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    122. Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements. RNA. 1996 Oct; 2(10):969-81. Hertel KJ, Lynch KW, Hsiao EC, Liu EH, Maniatis T. PMID: 8849774; PMCID: PMC1369430.
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