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Michael Rowbotham, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentAnesthesia
Address2255 Post Street
San Francisco CA 94115
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    CHRONIC NEUROPATHIC PAIN MECHANISMS AND MANAGEMENT
    NIH/NINDS K24NS002164Jun 28, 2000 - Apr 30, 2005
    Role: Principal Investigator
    PAIN &NEURAL DYSFUNCTION FROM ACUTE HERPES ZOSTER
    NIH/NINDS R01NS039521Feb 1, 2000 - Jan 31, 2005
    Role: Co-Principal Investigator
    MECHANISMS OF PAIN AND ANALGESIA
    NIH/NINDS P50NS021445Jan 1, 1985 - Dec 31, 2005
    Role: Co-Investigator
    DRUG DEPENDENCE CLINICAL RESEARCH PROGRAM
    NIH/NIDA P50DA001696Feb 1, 1978 - Aug 31, 2000
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. J Pain. 2017 May; 18(5):479-489. PMID: 28495013.
      View in: PubMed
    2. Kent ML, Tighe PJ, Belfer I, Brennan TJ, Bruehl S, Brummett CM, Buckenmaier CC, Buvanendran A, Cohen RI, Desjardins P, Edwards D, Fillingim R, Gewandter J, Gordon DB, Hurley RW, Kehlet H, Loeser JD, Mackey S, McLean SA, Polomano R, Rahman S, Raja S, Rowbotham M, Suresh S, Schachtel B, Schreiber K, Schumacher M, Stacey B, Stanos S, Todd K, Turk DC, Weisman SJ, Wu C, Carr DB, Dworkin RH, Terman G. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions. Pain Med. 2017 05 01; 18(5):947-958. PMID: 28482098.
      View in: PubMed
    3. Grady C, Cummings SR, Rowbotham M, McConnell MV, Ashley EA, Kang G. Informed Consent. N Engl J Med. 2017 03 02; 376(9):856-867. PMID: 28249147.
      View in: PubMed
    4. Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham M, Tobias JK, Wasan AD, Witter J. The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations. J Pain. 2017 Jul; 18(7):757-777. PMID: 28254585.
      View in: PubMed
    5. Gewandter JS, Kitt RA, Hunsinger MR, Poku J, Lozano J, Chaudari J, Evans S, Gross RA, McDermott MP, Rowbotham M, Turk DC, Dworkin RH. Reporting of data monitoring boards in publications of randomized clinical trials is often deficient: ACTTION systematic review. J Clin Epidemiol. 2017 Mar; 83:101-107. PMID: 28126598.
      View in: PubMed
    6. Williams MR, McKeown A, Pressman Z, Hunsinger M, Lee K, Coplan P, Gilron I, Katz NP, McDermott MP, Raja SN, Rappaport BA, Rowbotham M, Turk DC, Dworkin RH, Smith SM. Adverse Event Reporting in Clinical Trials of Intravenous and Invasive Pain Treatments: An ACTTION Systematic Review. J Pain. 2016 Nov; 17(11):1137-1149. PMID: 27522950.
      View in: PubMed
    7. Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork NJ, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham M, Browner WS, Cummings SR. Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1418-24. PMID: 26328603; PMCID: PMC4612388 [Available on 11/01/16].
    8. Rowbotham M. Tricyclic antidepressants and opioids-better together? Pain. 2015 Aug; 156(8):1373-4. PMID: 25867125.
      View in: PubMed
    9. Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol. 2015 Feb; 14(2):162-73. PMID: 25575710; PMCID: PMC4493167.
    10. Dufka FL, Munch T, Dworkin RH, Rowbotham M. Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT, and RReMiT databases. Pain. 2015 Jan; 156(1):72-80. PMID: 25599303; PMCID: PMC4280280.
    11. McKeown A, Gewandter JS, McDermott MP, Pawlowski JR, Poli JJ, Rothstein D, Farrar JT, Gilron I, Katz NP, Lin AH, Rappaport BA, Rowbotham M, Turk DC, Dworkin RH, Smith SM. Reporting of sample size calculations in analgesic clinical trials: ACTTION systematic review. J Pain. 2015 Mar; 16(3):199-206.e1-7. PMID: 25481494.
      View in: PubMed
    12. Gewandter JS, McKeown A, McDermott MP, Dworkin JD, Smith SM, Gross RA, Hunsinger M, Lin AH, Rappaport BA, Rice AS, Rowbotham M, Williams MR, Turk DC, Dworkin RH. Data interpretation in analgesic clinical trials with statistically nonsignificant primary analyses: an ACTTION systematic review. J Pain. 2015 Jan; 16(1):3-10. PMID: 25451621.
      View in: PubMed
    13. Gewandter JS, McDermott MP, McKeown A, Smith SM, Pawlowski JR, Poli JJ, Rothstein D, Williams MR, Bujanover S, Farrar JT, Gilron I, Katz NP, Rowbotham M, Turk DC, Dworkin RH. Reporting of intention-to-treat analyses in recent analgesic clinical trials: ACTTION systematic review and recommendations. Pain. 2014 Dec; 155(12):2714-9. PMID: 25284072.
      View in: PubMed
    14. Dufka FL, Dworkin RH, Rowbotham M. How transparent are migraine clinical trials? Repository of Registered Migraine Trials (RReMiT). Neurology. 2014 Oct 07; 83(15):1372-81. PMID: 25194013; PMCID: PMC4189098.
    15. Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, Dionne R, Farrar JT, Hewitt DJ, Iyengar S, Jay GW, Kalso E, Kerns RD, Leff R, Leong M, Petersen KL, Ravina BM, Rauschkolb C, Rice AS, Rowbotham M, Sampaio C, Sindrup SH, Stauffer JW, Steigerwald I, Stewart J, Tobias J, Treede RD, Wallace M, White RE. Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations. Pain. 2014 Sep; 155(9):1683-95. PMID: 24865794; PMCID: PMC4500524.
    16. Farrar JT, Troxel AB, Haynes K, Gilron I, Kerns RD, Katz NP, Rappaport BA, Rowbotham M, Tierney AM, Turk DC, Dworkin RH. Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study. Pain. 2014 Aug; 155(8):1622-31. PMID: 24831421.
      View in: PubMed
    17. Munch T, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham M. RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results. Pain. 2014 Jul; 155(7):1313-7. PMID: 24726925.
      View in: PubMed
    18. Slagelse C, Petersen KL, Dahl JB, Finnerup K, Greene K, Leong SP, Levine J, Rowbotham M, Werner MU, Finnerup NB. Persistent postoperative pain and sensory changes following lymph node excision in melanoma patients: a topical review. Melanoma Res. 2014 Apr; 24(2):93-8. PMID: 24346167.
      View in: PubMed
    19. O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, Comer SD, Cone E, Cowan P, Denisco RA, Farrar JT, Foltin RW, Haddox JD, Hertz S, Jay GW, Junor R, Kopecky EA, Leiderman DB, McDermott MP, Palmer PP, Raja SN, Rauschkolb C, Rowbotham M, Sampaio C, Setnik B, Smith SM, Sokolowska M, Stauffer JW, Walsh SL, Zacny JP. Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations. Pain. 2013 Nov; 154(11):2324-34. PMID: 24148704.
      View in: PubMed
    20. Smith SM, Wang AT, Pereira A, Chang RD, McKeown A, Greene K, Rowbotham M, Burke LB, Coplan P, Gilron I, Hertz SH, Katz NP, Lin AH, McDermott MP, Papadopoulos EJ, Rappaport BA, Sweeney M, Turk DC, Dworkin RH. Discrepancies between registered and published primary outcome specifications in analgesic trials: ACTTION systematic review and recommendations. Pain. 2013 Dec; 154(12):2769-74. PMID: 23962590.
      View in: PubMed
    21. Tzabazis A, Aparici CM, Rowbotham M, Schneider MB, Etkin A, Yeomans DC. Shaped magnetic field pulses by multi-coil repetitive transcranial magnetic stimulation (rTMS) differentially modulate anterior cingulate cortex responses and pain in volunteers and fibromyalgia patients. Mol Pain. 2013 Jul 02; 9:33. PMID: 23819466; PMCID: PMC3750766.
    22. Pereira MP, Werner MU, Ringsted TK, Rowbotham M, Taylor BK, Dahl JB. Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study. PLoS One. 2013; 8(5):e64608. PMID: 23741350; PMCID: PMC3669421.
    23. Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Farrar JT, Katz NP, Lin AH, Rappaport BA, Rowbotham M. Assay sensitivity and study features in neuropathic pain trials: an ACTTION meta-analysis. Neurology. 2013 Jul 02; 81(1):67-75. PMID: 23700332; PMCID: PMC3770199.
    24. Werner MU, Petersen KL, Rowbotham M, Dahl JB. Healthy volunteers can be phenotyped using cutaneous sensitization pain models. PLoS One. 2013; 8(5):e62733. PMID: 23671631; PMCID: PMC3650051.
    25. Reda H, Greene K, Rice FL, Rowbotham M, Petersen KL. Natural history of herpes zoster: late follow-up of 3.9 years (n=43) and 7.7 years (n=10). Pain. 2013 Oct; 154(10):2227-33. PMID: 23719573.
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    26. Smith SM, Wang AT, Katz NP, McDermott MP, Burke LB, Coplan P, Gilron I, Hertz SH, Lin AH, Rappaport BA, Rowbotham M, Sampaio C, Sweeney M, Turk DC, Dworkin RH. Adverse event assessment, analysis, and reporting in recent published analgesic clinical trials: ACTTION systematic review and recommendations. Pain. 2013 Jul; 154(7):997-1008. PMID: 23602344.
      View in: PubMed
    27. Rowbotham M, Gilron I, Glazer C, Rice AS, Smith BH, Stewart WF, Wasan AD. Can pragmatic trials help us better understand chronic pain and improve treatment? Pain. 2013 May; 154(5):643-6. PMID: 23541132.
      View in: PubMed
    28. Rowbotham M, Astin J, Greene K, Cummings SR. Interactive informed consent: randomized comparison with paper consents. PLoS One. 2013; 8(3):e58603. PMID: 23484041; PMCID: PMC3590180.
    29. Finnerup NB, Scholz J, Attal N, Baron R, Haanpää M, Hansson P, Raja SN, Rice AS, Rief W, Rowbotham M, Simpson DM, Treede RD. Neuropathic pain needs systematic classification. Eur J Pain. 2013 Aug; 17(7):953-6. PMID: 23339030.
      View in: PubMed
    30. Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, Farrar JT, Haddox JD, Haythornthwaite JA, Hertz S, Jay GW, Johanson CE, Junor R, Katz NP, Klein M, Kopecky EA, Leiderman DB, McDermott MP, O'Brien C, O'Connor AB, Palmer PP, Raja SN, Rappaport BA, Rauschkolb C, Rowbotham M, Sampaio C, Setnik B, Sokolowska M, Stauffer JW, Walsh SL. Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations. Pain. 2012 Dec; 153(12):2315-24. PMID: 22998781; PMCID: PMC3494795.
    31. Smith SM, Chang RD, Pereira A, Shah N, Gilron I, Katz NP, Lin AH, McDermott MP, Rappaport BA, Rowbotham M, Sampaio C, Turk DC, Dworkin RH. Adherence to CONSORT harms-reporting recommendations in publications of recent analgesic clinical trials: an ACTTION systematic review. Pain. 2012 Dec; 153(12):2415-21. PMID: 22985899.
      View in: PubMed
    32. Greene K, Dworkin RH, Rowbotham M. A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database. Pain. 2012 Sep; 153(9):1794-7. PMID: 22795917.
      View in: PubMed
    33. Campbell CM, Kipnes MS, Stouch BC, Brady KL, Kelly M, Schmidt WK, Petersen KL, Rowbotham M, Campbell JN. Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy. Pain. 2012 Sep; 153(9):1815-23. PMID: 22683276; PMCID: PMC3413770.
    34. Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham M, Backonja MM, Baron R, Bellamy N, Bhagwagar Z, Costello A, Cowan P, Fang WC, Hertz S, Jay GW, Junor R, Kerns RD, Kerwin R, Kopecky EA, Lissin D, Malamut R, Markman JD, McDermott MP, Munera C, Porter L, Rauschkolb C, Rice AS, Sampaio C, Skljarevski V, Sommerville K, Stacey BR, Steigerwald I, Tobias J, Trentacosti AM, Wasan AD, Wells GA, Williams J, Witter J, Ziegler D. Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations. Pain. 2012 Jun; 153(6):1148-58. PMID: 22494920.
      View in: PubMed
    35. Rowbotham M, Arslanian A, Nothaft W, Duan WR, Best AE, Pritchett Y, Zhou Q, Stacey BR. Efficacy and safety of the a4ß2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain. Pain. 2012 Apr; 153(4):862-8. PMID: 22386472.
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    36. Rowbotham M, Leong SP. How to reduce the incidence of neuropathic pain: sentinel node biopsy for diagnosis of metastatic malignant melanoma. Pain. 2011 Dec; 152(12):2681-2. PMID: 21983239.
      View in: PubMed
    37. Rowbotham M, Nothaft W, Duan WR, Wang Y, Faltynek C, McGaraughty S, Chu KL, Svensson P. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain. 2011 May; 152(5):1192-200. PMID: 21377273.
      View in: PubMed
    38. Jensen-Dahm C, Rowbotham M, Reda H, Petersen KL. Effect of a single dose of pregabalin on herpes zoster pain. Trials. 2011 Feb 28; 12:55. PMID: 21356040; PMCID: PMC3059274.
    39. Dworkin RH, Turk DC, Katz NP, Rowbotham M, Peirce-Sandner S, Cerny I, Clingman CS, Eloff BC, Farrar JT, Kamp C, McDermott MP, Rappaport BA, Sanhai WR. Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION. Pain. 2011 Mar; 152(3 Suppl):S107-15. PMID: 21145657.
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    40. Haanpää M, Attal N, Backonja M, Baron R, Bennett M, Bouhassira D, Cruccu G, Hansson P, Haythornthwaite JA, Iannetti GD, Jensen TS, Kauppila T, Nurmikko TJ, Rice AS, Rowbotham M, Serra J, Sommer C, Smith BH, Treede RD. NeuPSIG guidelines on neuropathic pain assessment. Pain. 2011 Jan; 152(1):14-27. PMID: 20851519.
      View in: PubMed
    41. Petersen KL, Rice FL, Farhadi M, Reda H, Rowbotham M. Natural history of cutaneous innervation following herpes zoster. Pain. 2010 Jul; 150(1):75-82. PMID: 20457490.
      View in: PubMed
    42. Petersen KL, Rowbotham M. Natural history of sensory function after herpes zoster. Pain. 2010 Jul; 150(1):83-92. PMID: 20452122.
      View in: PubMed
    43. Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham M, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM. Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain. 2010 Sep; 11(9):807-29. PMID: 20430701.
      View in: PubMed
    44. Rowbotham M. Pain's policy on the spinal administration of drugs. Pain. 2010 Jun; 149(3):415-6. PMID: 20202752.
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    45. Rowbotham M. The case for publishing 'negative' clinical trials. Pain. 2009 Dec; 146(3):225-6. PMID: 19853380.
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    46. Moore RA, Derry S, McQuay HJ, Straube S, Aldington D, Wiffen P, Bell RF, Kalso E, Rowbotham M. Clinical effectiveness: an approach to clinical trial design more relevant to clinical practice, acknowledging the importance of individual differences. Pain. 2010 May; 149(2):173-6. PMID: 19748185.
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    47. Rowbotham M, Duan WR, Thomas J, Nothaft W, Backonja MM. A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain. Pain. 2009 Dec; 146(3):245-52. PMID: 19632048.
      View in: PubMed
    48. Chizh BA, Priestley T, Rowbotham M, Schaffler K. Predicting therapeutic efficacy - experimental pain in human subjects. Brain Res Rev. 2009 Apr; 60(1):243-54. PMID: 19168094.
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    49. Rowbotham M. The impact of selective publication on clinical research in pain. Pain. 2008 Dec; 140(3):401-4. PMID: 19004556.
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    50. Mitchell JM, Bergren LJ, Chen KS, Rowbotham M, Fields HL. Naltrexone aversion and treatment efficacy are greatest in humans and rats that actively consume high levels of alcohol. Neurobiol Dis. 2009 Jan; 33(1):72-80. PMID: 18955144.
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    51. Rowbotham M. How should treatment results from clinical practice be reported? Pain. 2008 Sep 15; 138(3):475-6. PMID: 18722713.
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    52. Quessy SN, Rowbotham M. Placebo response in neuropathic pain trials. Pain. 2008 Sep 15; 138(3):479-83. PMID: 18706762.
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    53. Stacey BR, Barrett JA, Whalen E, Phillips KF, Rowbotham M. Pregabalin for postherpetic neuralgia: placebo-controlled trial of fixed and flexible dosing regimens on allodynia and time to onset of pain relief. J Pain. 2008 Nov; 9(11):1006-17. PMID: 18640074.
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    54. Petersen KL, Meadoff T, Press S, Peters MM, LeComte MD, Rowbotham M. Changes in morphine analgesia and side effects during daily subcutaneous administration in healthy volunteers. Pain. 2008 Jul 15; 137(2):395-404. PMID: 17977662.
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    55. Rowbotham M, Lindsey CD. How effective is long-term opioid therapy for chronic noncancer pain? Clin J Pain. 2007 May; 23(4):300-2. PMID: 17449989.
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    56. Petersen KL, Rowbotham M. Relief of post-herpetic neuralgia by surgical removal of painful skin: 5 years later. Pain. 2007 Sep; 131(1-2):214-8. PMID: 17451877; PMCID: PMC2020855.
    57. Abrams DI, Jay CA, Shade SB, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham M, Petersen KL. Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial. Neurology. 2007 Feb 13; 68(7):515-21. PMID: 17296917.
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    58. Mitchell JM, Fields HL, White RL, Meadoff TM, Joslyn G, Rowbotham M. The Asp40 mu-opioid receptor allele does not predict naltrexone treatment efficacy in heavy drinkers. J Clin Psychopharmacol. 2007 Feb; 27(1):112-5. PMID: 17224736.
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    59. Dworkin RH, Johnson RW, Breuer J, Gnann JW, Levin MJ, Backonja M, Betts RF, Gershon AA, Haanpaa ML, McKendrick MW, Nurmikko TJ, Oaklander AL, Oxman MN, Pavan-Langston D, Petersen KL, Rowbotham M, Schmader KE, Stacey BR, Tyring SK, van Wijck AJ, Wallace MS, Wassilew SW, Whitley RJ. Recommendations for the management of herpes zoster. Clin Infect Dis. 2007 Jan 01; 44 Suppl 1:S1-26. PMID: 17143845.
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    60. Kajdasz DK, Iyengar S, Desaiah D, Backonja MM, Farrar JT, Fishbain DA, Jensen TS, Rowbotham M, Sang CN, Ziegler D, McQuay HJ. Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. Clin Ther. 2007; 29 Suppl:2536-46. PMID: 18164920.
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    61. Frymoyer AR, Rowbotham M, Petersen KL. Placebo-controlled comparison of a morphine/dextromethorphan combination with morphine on experimental pain and hyperalgesia in healthy volunteers. J Pain. 2007 Jan; 8(1):19-25. PMID: 17113353.
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    62. Thyregod HG, Rowbotham M, Peters M, Possehn J, Berro M, Petersen KL. Natural history of pain following herpes zoster. Pain. 2007 Mar; 128(1-2):148-56. PMID: 17070998; PMCID: PMC1905461.
    63. Leung JM, Sands LP, Rico M, Petersen KL, Rowbotham M, Dahl JB, Ames C, Chou D, Weinstein P. Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. Neurology. 2006 Oct 10; 67(7):1251-3. PMID: 16914695.
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    64. Petersen KL, Rowbotham M. Quantitative sensory testing scaled up for multicenter clinical research networks: a promising start. Pain. 2006 Aug; 123(3):219-20. PMID: 16781074.
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    65. Rowbotham M. Pharmacologic management of complex regional pain syndrome. Clin J Pain. 2006 Jun; 22(5):425-9. PMID: 16772796.
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    66. Rowbotham M. Mechanisms of neuropathic pain and their implications for the design of clinical trials. Neurology. 2005 Dec 29; 65(12 Suppl 4):S66-73. PMID: 16385106.
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    67. Rowbotham M, Reisner LA, Davies PS, Fields HL. Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial. J Pain. 2005 Nov; 6(11):741-6. PMID: 16275598.
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    68. Birklein F, Rowbotham M. Does pain change the brain? Neurology. 2005 Sep 13; 65(5):666-7. PMID: 16157896.
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    69. Rowbotham M. Is fibromyalgia a neuropathic pain syndrome? J Rheumatol Suppl. 2005 Aug; 75:38-40. PMID: 16078359.
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    70. Crofford LJ, Rowbotham M, Mease PJ, Russell IJ, Dworkin RH, Corbin AE, Young JP, LaMoreaux LK, Martin SA, Sharma U. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2005 Apr; 52(4):1264-73. PMID: 15818684.
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    71. Rowbotham M, Goli V, Kunz NR, Lei D. Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study. Pain. 2004 Aug; 110(3):697-706. PMID: 15288411.
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    72. Berry JD, Rowbotham M, Petersen KL. Complex regional pain syndrome-like symptoms during herpes zoster. Pain. 2004 Jul; 110(1-2):e1-12. PMID: 15275746.
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    73. Dworkin RH, Backonja M, Rowbotham M, Allen RR, Argoff CR, Bennett GJ, Bushnell MC, Farrar JT, Galer BS, Haythornthwaite JA, Hewitt DJ, Loeser JD, Max MB, Saltarelli M, Schmader KE, Stein C, Thompson D, Turk DC, Wallace MS, Watkins LR, Weinstein SM. Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol. 2003 Nov; 60(11):1524-34. PMID: 14623723.
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    74. Rowbotham M, Manville NS, Ren J. Pilot tolerability and effectiveness study of levetiracetam for postherpetic neuralgia. Neurology. 2003 Sep 23; 61(6):866-7. PMID: 14504347.
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    75. Petersen KL, Maloney A, Hoke F, Dahl JB, Rowbotham M. A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization. J Pain. 2003 Sep; 4(7):400-6. PMID: 14622682.
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    76. Rowbotham M, Twilling L, Davies PS, Reisner L, Taylor K, Mohr D. Oral opioid therapy for chronic peripheral and central neuropathic pain. N Engl J Med. 2003 Mar 27; 348(13):1223-32. PMID: 12660386.
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    77. Wallace MS, Rowbotham M, Katz NP, Dworkin RH, Dotson RM, Galer BS, Rauck RL, Backonja MM, Quessy SN, Meisner PD. A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain. Neurology. 2002 Dec 10; 59(11):1694-700. PMID: 12473754.
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    78. Galer BS, Jensen MP, Ma T, Davies PS, Rowbotham M. The lidocaine patch 5% effectively treats all neuropathic pain qualities: results of a randomized, double-blind, vehicle-controlled, 3-week efficacy study with use of the neuropathic pain scale. Clin J Pain. 2002 Sep-Oct; 18(5):297-301. PMID: 12218500.
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    79. Dirks J, Petersen KL, Rowbotham M, Dahl JB. Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization. Anesthesiology. 2002 Jul; 97(1):102-7. PMID: 12131110.
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    80. Petersen KL, Rice FL, Suess F, Berro M, Rowbotham M. Relief of post-herpetic neuralgia by surgical removal of painful skin. Pain. 2002 Jul; 98(1-2):119-26. PMID: 12098623.
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    81. Wallace MS, Rowbotham M, Bennett GJ, Jensen TS, Pladna R, Quessy S. A multicenter, double-blind, randomized, placebo-controlled crossover evaluation of a short course of 4030W92 in patients with chronic neuropathic pain. J Pain. 2002 Jun; 3(3):227-33. PMID: 14622777.
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    82. Campbell BJ, Rowbotham M, Davies PS, Jacob P, Benowitz NL. Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. J Pharm Sci. 2002 May; 91(5):1343-50. PMID: 11977110.
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    83. Rowbotham M. What is a "clinically meaningful" reduction in pain? Pain. 2001 Nov; 94(2):131-2. PMID: 11690725.
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    84. Dirks J, Petersen KL, Rowbotham M, Dahl JB. Effect of systemic adenosine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. Reg Anesth Pain Med. 2001 Sep-Oct; 26(5):414-9. PMID: 11561260.
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    85. Rowbotham M, Petersen KL. Zoster-associated pain and neural dysfunction. Pain. 2001 Jul; 93(1):1-5. PMID: 11406332.
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    86. Mikkelsen S, Dirks J, Fabricius P, Petersen KL, Rowbotham M, Dahl JB. Effect of intravenous magnesium on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. Br J Anaesth. 2001 Jun; 86(6):871-3. PMID: 11573598.
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    87. Petersen KL, Jones B, Segredo V, Dahl JB, Rowbotham M. Effect of remifentanil on pain and secondary hyperalgesia associated with the heat--capsaicin sensitization model in healthy volunteers. Anesthesiology. 2001 Jan; 94(1):15-20. PMID: 11135717.
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    88. Petersen KL, Fields HL, Brennum J, Sandroni P, Rowbotham M. Capsaicin evoked pain and allodynia in post-herpetic neuralgia. Pain. 2000 Nov; 88(2):125-33. PMID: 11050367.
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    89. Galer BS, Twilling LL, Harle J, Cluff RS, Friedman E, Rowbotham M. Lack of efficacy of riluzole in the treatment of peripheral neuropathic pain conditions. Neurology. 2000 Oct 10; 55(7):971-5. PMID: 11061253.
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    90. Dirks J, Fabricius P, Petersen KL, Rowbotham M, Dahl JB. The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. Anesth Analg. 2000 Oct; 91(4):967-72. PMID: 11004058.
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    91. Petersen KL, Rowbotham M. Will ion-channel blockers be useful for management of nonneuropathic pain? J Pain. 2000 Sep; 1(3 Suppl):26-34. PMID: 14622840.
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    92. Dworkin RH, Galer BS, Rowbotham M. Herpes zoster. N Engl J Med. 2000 Jul 20; 343(3):221-2; author reply 223. PMID: 10928867.
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    93. Galer BS, Rowbotham M, Perander J, Devers A, Friedman E. Topical diclofenac patch relieves minor sports injury pain: results of a multicenter controlled clinical trial. J Pain Symptom Manage. 2000 Apr; 19(4):287-94. PMID: 10799795.
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    94. Everhart ET, Shwonek P, Jacob P, Rowbotham M, Jones RT. Quantitation of levorphanol in human plasma at subnanogram per milliliter levels using capillary gas chromatography with electron-capture detection. J Chromatogr B Biomed Sci Appl. 1999 Jun 11; 729(1-2):173-81. PMID: 10410940.
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    95. Petersen KL, Rowbotham M. A new human experimental pain model: the heat/capsaicin sensitization model. Neuroreport. 1999 May 14; 10(7):1511-6. PMID: 10380972.
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    96. Galer BS, Rowbotham M, Perander J, Friedman E. Topical lidocaine patch relieves postherpetic neuralgia more effectively than a vehicle topical patch: results of an enriched enrollment study. Pain. 1999 Apr; 80(3):533-8. PMID: 10342414.
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    97. Baron R, Wasner G, Borgstedt R, Hastedt E, Schulte H, Binder A, Kopper F, Rowbotham M, Levine JD, Fields HL. Effect of sympathetic activity on capsaicin-evoked pain, hyperalgesia, and vasodilatation. Neurology. 1999 Mar 23; 52(5):923-32. PMID: 10102407.
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    98. Yosipovitch G, Maibach HI, Rowbotham M. Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia. Acta Derm Venereol. 1999 Mar; 79(2):118-21. PMID: 10228629.
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    99. Dempsey D, Jacob P, Partridge JC, Jones RT, Panganiban K, Rowbotham M. Cocaine metabolite kinetics in the newborn. J Anal Toxicol. 1999 Jan-Feb; 23(1):24-8. PMID: 10022205.
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    100. Rowbotham M, Harden N, Stacey B, Bernstein P, Magnus-Miller L. Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial. JAMA. 1998 Dec 02; 280(21):1837-42. PMID: 9846778.
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    101. Cluff RS, Rowbotham M. Pain caused by herpes zoster infection. Neurol Clin. 1998 Nov; 16(4):813-32. PMID: 9767064.
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    102. Fields HL, Rowbotham M, Baron R. Postherpetic neuralgia: irritable nociceptors and deafferentation. Neurobiol Dis. 1998 Oct; 5(4):209-27. PMID: 9848092.
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    103. Rowbotham M. Complex regional pain syndrome type I (reflex sympathetic dystrophy): more than a myth. Neurology. 1998 Jul; 51(1):4-5. PMID: 9674766.
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    104. Dempsey DA, Partridge JC, Jones RT, Rowbotham M. Cocaine, nicotine, caffeine, and metabolite plasma concentrations in neonates. J Anal Toxicol. 1998 May-Jun; 22(3):220-4. PMID: 9602939.
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    105. Choi B, Rowbotham M. Effect of adrenergic receptor activation on post-herpetic neuralgia pain and sensory disturbances. Pain. 1997 Jan; 69(1-2):55-63. PMID: 9060013.
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    106. Taylor K, Rowbotham M. Venlafaxine hydrochloride and chronic pain. West J Med. 1996 Sep; 165(3):147-8. PMID: 8909172; PMCID: PMC1303727.
    107. Galer BS, Harle J, Rowbotham M. Response to intravenous lidocaine infusion predicts subsequent response to oral mexiletine: a prospective study. J Pain Symptom Manage. 1996 Sep; 12(3):161-7. PMID: 8803379.
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    108. Rowbotham M, Davies PS, Verkempinck C, Galer BS. Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia. Pain. 1996 Apr; 65(1):39-44. PMID: 8826488.
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    109. Rowbotham M, Fields HL. The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia. Brain. 1996 Apr; 119 ( Pt 2):347-54. PMID: 8800931.
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    110. Rowbotham M, Yosipovitch G, Connolly MK, Finlay D, Forde G, Fields HL. Cutaneous innervation density in the allodynic form of postherpetic neuralgia. Neurobiol Dis. 1996; 3(3):205-14. PMID: 8980021.
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    111. Rowbotham M. Chronic pain: from theory to practical management. Neurology. 1995 Dec; 45(12 Suppl 9):S5-10; discussion S35-6. PMID: 8538884.
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    112. Rowbotham M, Davies PS, Fields HL. Topical lidocaine gel relieves postherpetic neuralgia. Ann Neurol. 1995 Feb; 37(2):246-53. PMID: 7847866.
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    113. Dellemijn PL, Fields HL, Allen RR, McKay WR, Rowbotham M. The interpretation of pain relief and sensory changes following sympathetic blockade. Brain. 1994 Dec; 117 ( Pt 6):1475-87. PMID: 7820581.
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    114. Rowbotham M. Postherpetic neuralgia. Semin Neurol. 1994 Sep; 14(3):247-54. PMID: 7701125.
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    115. Rowbotham M. Managing post-herpetic neuralgia with opioids and local anesthetics. Ann Neurol. 1994; 35 Suppl:S46-9. PMID: 8185298.
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    116. Galer BS, Miller KV, Rowbotham M. Response to intravenous lidocaine infusion differs based on clinical diagnosis and site of nervous system injury. Neurology. 1993 Jun; 43(6):1233-5. PMID: 8170571.
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    117. Rowbotham M. Treatment of postherpetic neuralgia. Semin Dermatol. 1992 Sep; 11(3):218-25. PMID: 1390037.
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    118. Galer BS, Rowbotham M, Von Miller K, Walton A, Fields HL. Treatment of inflammatory, neuropathic and sympathetically maintained pain in a patient with Sjögren's syndrome. Pain. 1992 Aug; 50(2):205-8. PMID: 1408318.
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    119. Rowbotham M, Reisner-Keller LA, Fields HL. Both intravenous lidocaine and morphine reduce the pain of postherpetic neuralgia. Neurology. 1991 Jul; 41(7):1024-8. PMID: 1712433.
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    120. Rowbotham M, Lowenstein DH. Neurologic consequences of cocaine use. Annu Rev Med. 1990; 41:417-22. PMID: 2184741.
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    121. Rowbotham M, Fields HL. Post-herpetic neuralgia: the relation of pain complaint, sensory disturbance, and skin temperature. Pain. 1989 Nov; 39(2):129-44. PMID: 2594392.
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    122. Rowbotham M, Fields HL. Topical lidocaine reduces pain in post-herpetic neuralgia. Pain. 1989 Sep; 38(3):297-301. PMID: 2478945.
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    123. Rowley HA, Lowenstein DH, Rowbotham M, Simon RP. Thalamomesencephalic strokes after cocaine abuse. Neurology. 1989 Mar; 39(3):428-30. PMID: 2927656.
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    124. Rowbotham M. Neurologic aspects of cocaine abuse. West J Med. 1988 Oct; 149(4):442-8. PMID: 3067448; PMCID: PMC1026490.
    125. Lowenstein DH, Massa SM, Rowbotham M, Collins SD, McKinney HE, Simon RP. Acute neurologic and psychiatric complications associated with cocaine abuse. Am J Med. 1987 Nov; 83(5):841-6. PMID: 3674091.
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    126. Rowbotham M, Hooker WD, Mendelson J, Jones RT. Cocaine-calcium channel antagonist interactions. Psychopharmacology (Berl). 1987; 93(2):152-4. PMID: 3122247.
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    127. Rowbotham M, Jones RT, Benowitz NL, Jacob P. Trazodone-oral cocaine interactions. Arch Gen Psychiatry. 1984 Sep; 41(9):895-9. PMID: 6380447.
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    128. Rowbotham M, Joseph MS, Jones RT, Keil LC. Failure of naloxone to reverse apomorphine effects in humans. Psychoneuroendocrinology. 1983; 8(1):95-102. PMID: 6308702.
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