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Patricia Arean, PhD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
Phone415-476-7817
ORCID ORCID Icon0000-0001-5971-6319 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    UW ALACRITY Center for Psychosocial Interventions Research
    NIH/NIMH P50MH115837May 15, 2018 - Apr 30, 2022
    Role: Principal Investigator
    A Computerized Intervention Targeting Cognitive Control Network Deficits in Depression
    NIH/NIMH R61MH110509Nov 13, 2017 - Aug 31, 2018
    Role: Principal Investigator
    A Computerized Intervention Targeting Cognitive Control Network Deficits in Depression
    NIH/NIMH R33MH110509Sep 19, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Scaling a smarter and more efficient intervention: Evaluating the feasibility of disseminating a novel mobile app platform to treat depression
    NIH/NIMH R34MH110583Aug 1, 2016 - Oct 31, 2018
    Role: Co-Principal Investigator
    Strategic and Plasticity Interventions for Late Life Depression in Community Settings
    NIH/NIMH K24MH074717Sep 1, 2015 - Dec 31, 2016
    Role: Principal Investigator
    Enhancing Cognitive Control in Older Adults with Complementary Interventions
    NIH/NIA R01AG049424Aug 15, 2015 - May 31, 2020
    Role: Co-Principal Investigator
    2/2 Stepped, reward-exposure based therapy vs. PST in late life depression
    NIH/NIMH R01MH102304Apr 15, 2014 - Mar 31, 2019
    Role: Principal Investigator
    Can mental health apps work in the real world? A feasibility pilot study
    NIH/NIMH R34MH100466Jun 24, 2013 - Mar 31, 2016
    Role: Principal Investigator
    CATALAC: Community-Academic Treatment &Assessment for Low-Income Aged Consumers
    NIH/NIMH R24MH077192Apr 1, 2008 - Sep 29, 2011
    Role: Principal Investigator
    Case Management and PST for Depressed Homebound Low-Income Elders
    NIH/NIMH R01MH075900Apr 1, 2007 - Mar 31, 2013
    Role: Principal Investigator
    Community-Academic Research Training Alliance (CARTA)
    NIH/NIMH R25MH074500Sep 26, 2005 - Jul 31, 2011
    Role: Principal Investigator
    PST in Geriatric Depression with Executive Dysfunction
    NIH/NIMH R01MH063982Sep 20, 2002 - May 31, 2007
    Role: Principal Investigator
    TREATMENTS FOR DEPRESSED ELDERLY PRIMARY CARE PATIENTS
    NIH/NIMH R29MH051956Dec 1, 1994 - Aug 31, 1999
    Role: Principal Investigator
    Clinical Services Research Training Program
    NIH/NIMH T32MH018261Aug 1, 1985 - Jun 30, 2020
    Role: Co-Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A randomized controlled trial of internet-delivered cognitive behaviour therapy to prevent the development of depressive disorders in older adults with multimorbidity. J Affect Disord. 2020 Mar 01; 264:464-473. Read J, Sharpe L, Burton AL, Arean PA, Raue PJ, McDonald S, Titov N, Gandy M, Dear BF. PMID: 31767215.
      View in: PubMed   Mentions:    Fields:    
    2. Towards a consensus around standards for smartphone apps and digital mental health. World Psychiatry. 2019 Feb; 18(1):97-98. Torous J, Andersson G, Bertagnoli A, Christensen H, Cuijpers P, Firth J, Haim A, Hsin H, Hollis C, Lewis S, Mohr DC, Pratap A, Roux S, Sherrill J, Arean PA. PMID: 30600619.
      View in: PubMed   Mentions:
    3. Corrigendum to 'Does Cognition Predict Treatment Response and Remission in Psychotherapy for Late-Life Depression?' [The American Journal of Geriatric Psychiatry 23 (2015) 215-219]. Am J Geriatr Psychiatry. 2019 Apr; 27(4):461. Beaudreau SA, Rideaux T, O'Hara R, Arean P. PMID: 30622002.
      View in: PubMed   Mentions:    Fields:    
    4. Using Mobile Apps to Assess and Treat Depression in Hispanic and Latino Populations: Fully Remote Randomized Clinical Trial. J Med Internet Res. 2018 08 09; 20(8):e10130. Pratap A, Renn BN, Volponi J, Mooney SD, Gazzaley A, Arean PA, Anguera JA. PMID: 30093372.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. "Engage" therapy: Prediction of change of late-life major depression. J Affect Disord. 2017 10 15; 221:192-197. Alexopoulos GS, O'Neil R, Banerjee S, Raue PJ, Victoria LW, Bress JN, Pollari C, Arean PA. PMID: 28647669.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Pain severity predicts depressive symptoms over and above individual illnesses and multimorbidity in older adults. BMC Psychiatry. 2017 05 04; 17(1):166. Sharpe L, McDonald S, Correia H, Raue PJ, Meade T, Nicholas M, Arean P. PMID: 28472936.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. The feasibility, acceptability, and outcomes of PRIME-D: A novel mobile intervention treatment for depression. Depress Anxiety. 2017 06; 34(6):546-554. Schlosser DA, Campellone TR, Truong B, Anguera JA, Vergani S, Vinogradov S, Arean P. PMID: 28419621.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial. J Med Internet Res. 2016 12 20; 18(12):e330. Arean PA, Hallgren KA, Jordan JT, Gazzaley A, Atkins DC, Heagerty PJ, Anguera JA. PMID: 27998876.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    9. Mental Health Service Use Across the Life Course Among Adults With Psychiatric Disorders and Prior Suicidal Behavior. Psychiatr Serv. 2016 Apr 01; 67(4):452-5. Byers AL, Lai AX, Arean P, Nelson JC, Yaffe K. PMID: 26766753.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. "Engage" Therapy: Behavioral Activation and Improvement of Late-Life Major Depression. Am J Geriatr Psychiatry. 2016 Apr; 24(4):320-6. Alexopoulos GS, Raue PJ, Gunning F, Kiosses DN, Kanellopoulos D, Pollari C, Banerjee S, Arean PA. PMID: 26905044.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    11. The Sociocultural Context of Caregiving Experiences for Vietnamese Dementia Family Caregivers. Asian Am J Psychol. 2015 Sep; 6(3):263-272. Meyer OL, Nguyen KH, Dao TN, Vu P, Arean P, Hinton L. PMID: 26617956.
      View in: PubMed   Mentions:
    12. Role of Executive Dysfunction and Dysexecutive Behavior in Late-Life Depression and Disability. Am J Geriatr Psychiatry. 2015 Oct; 23(10):1038-45. Gansler DA, Suvak M, Arean P, Alexopoulos GS. PMID: 26209224.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Depression Treatment Uptake in Integrated Primary Care: How a "Warm Handoff" and Other Factors Affect Decision Making by Latinos. Psychiatr Serv. 2015 Aug 01; 66(8):824-30. Horevitz E, Organista KC, Arean PA. PMID: 25873022.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Causal and bidirectional linkages over time between depression and diabetes regimen distress in adults with type 2 diabetes. Diabetes Res Clin Pract. 2015 May; 108(2):360-6. Hessler D, Fisher L, Strycker LA, Arean PA, Bowyer V. PMID: 25819480.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Does cognition predict treatment response and remission in psychotherapy for late-life depression? Am J Geriatr Psychiatry. 2015 Feb; 23(2):215-9. Beaudreau SA, Rideaux T, O'Hara R, Arean P. PMID: 25441055.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. Comparing engage with PST in late-life major depression: a preliminary report. Am J Geriatr Psychiatry. 2015 May; 23(5):506-13. Alexopoulos GS, Raue PJ, Kiosses DN, Seirup JK, Banerjee S, Arean PA. PMID: 25081818.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    17. Choosing treatment for depression in older adults and evaluating response. Clin Geriatr Med. 2014 Aug; 30(3):535-51. Arean PA, Niu G. PMID: 25037294.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Do manualized treatments for depression reduce insomnia symptoms? J Clin Psychol. 2014 Jul; 70(7):616-30. Yon A, Scogin F, DiNapoli EA, McPherron J, Arean PA, Bowman D, Jamison CS, Karpe JA, Latour D, Reynolds CF, Rohen N, Pardini JE, Thompson LW. PMID: 24596077.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Association of age at depression onset with cognitive functioning in individuals with late-life depression and executive dysfunction. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1633-41. Mackin RS, Nelson JC, Delucchi KL, Raue PJ, Satre DD, Kiosses DN, Alexopoulos GS, Arean PA. PMID: 24680502.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    20. A model for streamlining psychotherapy in the RDoC era: the example of 'Engage'. Mol Psychiatry. 2014 Jan; 19(1):14-9. Alexopoulos GS, Arean P. PMID: 24280983.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    21. Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1496-503. Mackin RS, Nelson JC, Delucchi K, Raue P, Byers A, Barnes D, Satre DD, Yaffe K, Alexopoulos GS, Arean PA. PMID: 24378255.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    22. Reductions in regimen distress are associated with improved management and glycemic control over time. Diabetes Care. 2014; 37(3):617-24. Hessler D, Fisher L, Glasgow RE, Strycker LA, Dickinson LM, Arean PA, Masharani U. PMID: 24170750.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    23. REDEEM: a pragmatic trial to reduce diabetes distress. Diabetes Care. 2013 Sep; 36(9):2551-8. Fisher L, Hessler D, Glasgow RE, Arean PA, Masharani U, Naranjo D, Strycker LA. PMID: 23735726.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    24. Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response. Am J Geriatr Psychiatry. 2013 Aug; 21(8):794-802. Mackin RS, Tosun D, Mueller SG, Lee JY, Insel P, Schuff N, Truran-Sacrey D, Arean P, Nelson JC, Weiner MW. PMID: 23567394.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    25. Implementation Research: Reducing the Research-to-Practice Gap in Depression Treatment. Depress Res Treat. 2012; 2012:476027. Kilbourne AM, Williams M, Bauer MS, Arean P. PMID: 23326651.
      View in: PubMed   Mentions:
    26. Implementing evidence-based psychotherapies in settings serving older adults: challenges and solutions. Psychiatr Serv. 2012 Jun; 63(6):605-7. Arean PA, Raue PJ, Sirey JA, Snowden M. PMID: 22638006.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    27. Personalizing behavioral interventions: the case of late-life depression. Neuropsychiatry (London). 2012 Apr; 2(2):135-145. Arean PA. PMID: 23646065.
      View in: PubMed   Mentions:
    28. Depression is a common and chronic comorbidity in patients with interstitial lung disease. Respirology. 2012 Apr; 17(3):525-32. Ryerson CJ, Arean PA, Berkeley J, Carrieri-Kohlman VL, Pantilat SZ, Landefeld CS, Collard HR. PMID: 22221976.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    29. Low use of mental health services among older Americans with mood and anxiety disorders. Psychiatr Serv. 2012 Jan; 63(1):66-72. Byers AL, Arean PA, Yaffe K. PMID: 22227762.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    30. Home-delivered problem adaptation therapy (PATH) for depressed, cognitively impaired, disabled elders: A preliminary study. Am J Geriatr Psychiatry. 2010 Nov; 18(11):988-98. Kiosses DN, Arean PA, Teri L, Alexopoulos GS. PMID: 20808092.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    31. High-Yield Cognitive-Behavior Therapy for Brief Sessions: An Illustrated Guideby Wright Jesse H. Sudak Donna M. Turkington Douglas and Thase Michael E. Washington, DC , American Psychiatric Publishing , 2010 , 383 pp., $74.00 . Am J Psychiatry. 2010 Nov; 167(11):1413. Arean PA. PMID: 26649971.
      View in: PubMed   Mentions:    Fields:    
    32. Research on late-life depression and dementia care: across disciplines, across settings. Am J Geriatr Psychiatry. 2010 Jun; 18(6):457-9. Kiosses DN, Arean PA. PMID: 21217556.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Does mentoring matter: results from a survey of faculty mentees at a large health sciences university. Med Educ Online. 2010 Apr 23; 15. Feldman MD, Arean PA, Marshall SJ, Lovett M, O'Sullivan P. PMID: 20431710.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    34. Advantages of using estimated depression-free days for evaluating treatment efficacy. Psychiatr Serv. 2010 Feb; 61(2):160-3. Vannoy SD, Arean P, Unützer J. PMID: 20123821.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    35. Diabetes distress but not clinical depression or depressive symptoms is associated with glycemic control in both cross-sectional and longitudinal analyses. Diabetes Care. 2010 Jan; 33(1):23-8. Fisher L, Mullan JT, Arean P, Glasgow RE, Hessler D, Masharani U. PMID: 19837786.
      View in: PubMed   Mentions: 131     Fields:    Translation:Humans
    36. The selection and design of control conditions for randomized controlled trials of psychological interventions. Psychother Psychosom. 2009; 78(5):275-84. Mohr DC, Spring B, Freedland KE, Beckner V, Arean P, Hollon SD, Ockene J, Kaplan R. PMID: 19602916.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    37. Predicting diabetes distress in patients with Type 2 diabetes: a longitudinal study. Diabet Med. 2009 Jun; 26(6):622-7. Fisher L, Mullan JT, Skaff MM, Glasgow RE, Arean P, Hessler D. PMID: 19538238.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    38. Long term care staff beliefs about evidence based practices for the management of dementia and agitation. Int J Geriatr Psychiatry. 2009 Feb; 24(2):118-24. Ayalon L, Arean P, Bornfeld H, Beard R. PMID: 18563863.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with Type 2 diabetes. Diabet Med. 2008 Sep; 25(9):1096-101. Fisher L, Skaff MM, Mullan JT, Arean P, Glasgow R, Masharani U. PMID: 19183314.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    40. Problem solving therapy for the depression-executive dysfunction syndrome of late life. Int J Geriatr Psychiatry. 2008 Aug; 23(8):782-8. Alexopoulos GS, Raue PJ, Kanellopoulos D, Mackin S, Arean PA. PMID: 18213605.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    41. Effectiveness of problem-solving therapy for older, primary care patients with depression: results from the IMPACT project. Gerontologist. 2008 Jun; 48(3):311-23. Arean P, Hegel M, Vannoy S, Fan MY, Unuzter J. PMID: 18591356.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    42. Developing an intervention for depressed, chronically medically ill elders: a model from COPD. Int J Geriatr Psychiatry. 2008 May; 23(5):447-53. Alexopoulos GS, Raue PJ, Sirey JA, Arean PA. PMID: 17932995.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    43. Correlates of knowledge and beliefs about depression among long-term care staff. Int J Geriatr Psychiatry. 2008 Apr; 23(4):356-63. Ayalon L, Arean P, Bornfeld H. PMID: 17726711.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    44. The role of cognitive functioning and distress in suicidal ideation in older adults. J Am Geriatr Soc. 2007 Jul; 55(7):1090-4. Ayalon L, Mackin S, Arean PA, Chen H, McDonel Herr EC. PMID: 17608884.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Clinical depression versus distress among patients with type 2 diabetes: not just a question of semantics. Diabetes Care. 2007 Mar; 30(3):542-8. Fisher L, Skaff MM, Mullan JT, Arean P, Mohr D, Masharani U, Glasgow R, Laurencin G. PMID: 17327318.
      View in: PubMed   Mentions: 120     Fields:    Translation:Humans
    46. Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ. 2006 Feb 04; 332(7536):259-63. Hunkeler EM, Katon W, Tang L, Williams JW, Kroenke K, Lin EH, Harpole LH, Arean P, Levine S, Grypma LM, Hargreaves WA, Unützer J. PMID: 16428253.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansPHPublic Health
    47. Effect of improving depression care on pain and functional outcomes among older adults with arthritis: a randomized controlled trial. JAMA. 2003 Nov 12; 290(18):2428-9. Lin EH, Katon W, Von Korff M, Tang L, Williams JW, Kroenke K, Hunkeler E, Harpole L, Hegel M, Arean P, Hoffing M, Della Penna R, Langston C, Unützer J. PMID: 14612479.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansCTClinical Trials
    48. Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry. 2003 Jul; 60(7):664-72. Charney DS, Reynolds CF, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, Blazer DG, Katz IR, Meyers BS, Arean PA, Borson S, Brown C, Bruce ML, Callahan CM, Charlson ME, Conwell Y, Cuthbert BN, Devanand DP, Gibson MJ, Gottlieb GL, Krishnan KR, Laden SK, Lyketsos CG, Mulsant BH, Niederehe G, Olin JT, Oslin DW, Pearson J, Persky T, Pollock BG, Raetzman S, Reynolds M, Salzman C, Schulz R, Schwenk TL, Scolnick E, Unutzer J, Weissman MM, Young RC. PMID: 12860770.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    49. Impacting late life depression: integrating a depression intervention into primary care. Psychiatr Q. 2003; 74(1):75-89. Oishi SM, Shoai R, Katon W, Callahan C, Unützer J, Arean P, Callahan C, Della Penna R, Harpole L, Hegel M, Noel PH, Hoffing M, Hunkeler EM, Katon W, Levine S, Lin EH, Oddone E, Oishi S, Unützer J, Williams J. PMID: 12602790.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    50. Psychosocial treatment research with ethnic minority populations: ethical considerations in conducting clinical trials. Ethics Behav. 2002; 12(1):103-16. Alvidrez J, Arean PA. PMID: 12171080.
      View in: PubMed   Mentions:
    51. Ethical considerations in psychotherapy effectiveness research: choosing the comparison group. Ethics Behav. 2002; 12(1):63-73. Arean PA, Alvidrez J. PMID: 12171083.
      View in: PubMed   Mentions:
    52. Improving primary care for depression in late life: the design of a multicenter randomized trial. Med Care. 2001 Aug; 39(8):785-99. Unützer J, Katon W, Williams JW, Callahan CM, Harpole L, Hunkeler EM, Hoffing M, Arean P, Hegel MT, Schoenbaum M, Oishi SM, Langston CA. PMID: 11468498.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCTClinical Trials
    53. Methods for studying course of illness with severely mentally ill adults. Issues Ment Health Nurs. 1997 Nov-Dec; 18(6):623-38. Chafetz L, Havassy B, Arean P. PMID: 9384079.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Do primary care patients accept psychological treatments? Gen Hosp Psychiatry. 1996 Jan; 18(1):22-7. Arean PA, Miranda J. PMID: 8666209.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    55. Comparative effectiveness of social problem-solving therapy and reminiscence therapy as treatments for depression in older adults. J Consult Clin Psychol. 1993 Dec; 61(6):1003-10. Arean PA, Perri MG, Nezu AM, Schein RL, Christopher F, Joseph TX. PMID: 8113478.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCTClinical Trials
    56. Assertiveness and problem-solving training for mildly mentally retarded persons with dual diagnoses. Res Dev Disabil. 1991; 12(4):371-86. Nezu CM, Nezu AM, Arean P. PMID: 1792363.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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