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Preoperative Opioid Use Increases Postoperative Opioid Demand, but Not Length of Stay After Spine Trauma Surgery. World Neurosurg. 2024 Jun 29.
Castellini L, Barber J, Saigal R. PMID: 38950648.
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PubMed Mentions: Fields:
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ATF3 is a neuron-specific biomarker for spinal cord injury and ischaemic stroke. Clin Transl Med. 2024 Apr; 14(4):e1650.
Pan JZ, Wang Z, Sun W, Pan P, Li W, Sun Y, Chen S, Lin A, Tan W, He L, Greene J, Yao V, An L, Liang R, Li Q, Yu J, Zhang L, Kyritsis N, Fernandez XD, Moncivais S, Mendoza E, Fung P, Wang G, Niu X, Du Q, Xiao Z, Chang Y, Lv P, Huie JR, Torres-Espin A, Ferguson AR, Hemmerle DD, Talbott JF, Weinstein PR, Pascual LU, Singh V, DiGiorgio AM, Saigal R, Whetstone WD, Manley GT, Dhall SS, Bresnahan JC, Maze M, Jiang X, Singhal NS, Beattie MS, Su H, Guan Z. PMID: 38649772; PMCID: PMC11035380.
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Translation:
HumansAnimalsCells
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A Clinical Practice Guideline for Prevention, Diagnosis and Management of Intraoperative Spinal Cord Injury: Recommendations for Use of Intraoperative Neuromonitoring and for the Use of Preoperative and Intraoperative Protocols for Patients Undergoing Spine Surgery. Global Spine J. 2024 Mar; 14(3_suppl):212S-222S.
Fehlings MG, Alvi MA, Evaniew N, Tetreault LA, Martin AR, McKenna SL, Rahimi-Movaghar V, Ha Y, Kirshblum S, Hejrati N, Srikandarajah N, Quddusi A, Moghaddamjou A, Malvea A, Pinto RR, Marco RAW, Newcombe VFJ, Basu S, Strantzas S, Zipser CM, Douglas S, Laufer I, Chou D, Saigal R, Arnold PM, Hawryluk GWJ, Skelly AC, Kwon BK. PMID: 38526921; PMCID: PMC10964898.
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PubMed Mentions:
2
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An Update of a Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Role and Timing of Decompressive Surgery. Global Spine J. 2024 Mar; 14(3_suppl):174S-186S.
Fehlings MG, Tetreault LA, Hachem L, Evaniew N, Ganau M, McKenna SL, Neal CJ, Nagoshi N, Rahimi-Movaghar V, Aarabi B, Hofstetter CP, Wengel VT, Nakashima H, Martin AR, Kirshblum S, Rodrigues Pinto R, Marco RAW, Wilson JR, Kahn DE, Newcombe VFJ, Zipser CM, Douglas S, Kurpad SN, Lu Y, Saigal R, Samadani U, Arnold PM, Hawryluk GWJ, Skelly AC, Kwon BK. PMID: 38526922; PMCID: PMC10964895.
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PubMed Mentions:
5
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A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on Hemodynamic Management. Global Spine J. 2024 Mar; 14(3_suppl):187S-211S.
Kwon BK, Tetreault LA, Martin AR, Arnold PM, Marco RAW, Newcombe VFJ, Zipser CM, McKenna SL, Korupolu R, Neal CJ, Saigal R, Glass NE, Douglas S, Ganau M, Rahimi-Movaghar V, Harrop JS, Aarabi B, Wilson JR, Evaniew N, Skelly AC, Fehlings MG. PMID: 38526923; PMCID: PMC10964888.
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PubMed Mentions:
2
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Safety and comparative efficacy of initiating low-molecular-weight heparin within 24 hours of injury or surgery for venous thromboembolism prophylaxis in patients with spinal cord injury: a prospective TRACK-SCI registry study. Neurosurg Focus. 2023 10; 55(4):E17.
Lui A, Park C, Chryssikos T, Radabaugh H, Patel A, Aabedi AA, Ferguson AR, Torres Espin A, Mummaneni PV, Dhall SS, Duong-Fernandez X, Saigal R, Chou A, Pan J, Singh V, Hemmerle DD, Kyritsis N, Talbott JF, Pascual LU, Huie JR, Whetstone WD, Bresnahan JC, Beattie MS, Weinstein PR, Manley GT, DiGiorgio AM. PMID: 37778033.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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3D-Printed Polypyrrole Microneedle Arrays for Electronically Controlled Transdural Drug Release. ACS Biomater Sci Eng. 2022 04 11; 8(4):1544-1553.
Huang J, Yap N, Walter M, Green A, Smith C, Johnson J, Saigal R. PMID: 35294162.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Three Column Cervical Fracture-Dislocation in a 3-Year-Old Boy. Cureus. 2022 Mar; 14(3):e23213.
Sivakanthan S, Feroze A, Eaton J, Saigal R. PMID: 35449661; PMCID: PMC9012570.
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PubMed Mentions:
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Multisite Transcutaneous Spinal Stimulation for Walking and Autonomic Recovery in Motor-Incomplete Tetraplegia: A Single-Subject Design. Phys Ther. 2022 01 01; 102(1).
Samejima S, Caskey CD, Inanici F, Shrivastav SR, Brighton LN, Pradarelli J, Martinez V, Steele KM, Saigal R, Moritz CT. PMID: 35076067; PMCID: PMC8788019.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Drug delivery to the central nervous system. Nat Rev Mater. 2022 Apr; 7(4):314-331.
Nance E, Pun SH, Saigal R, Sellers DL. PMID: 38464996; PMCID: PMC10923597.
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PubMed Mentions:
15
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Impact of surgeon rhBMP-2 cost awareness on complication rates and health system costs for spinal arthrodesis. Neurosurg Focus. 2021 06; 50(6):E5.
McGrath M, Feroze AH, Nistal D, Robinson E, Saigal R. PMID: 34062498.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Commentary: Prognostic Factors Associated With Surviving Less Than 3 Months vs Greater Than 3 Years Specific to Spine Stereotactic Body Radiotherapy and Late Adverse Events. Neurosurgery. 2021 04 15; 88(5):E406-E407.
Eastman BM, Saigal R, Hofstetter CP, Foote M, Mayr NA, Lo SS. PMID: 33582789.
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Translation:
Humans
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Impact of New Motor Deficit on HRQOL After Adult Spinal Deformity Surgery: Subanalysis From Scoli Risk 1 Prospective Study. Spine (Phila Pa 1976). 2021 Apr 01; 46(7):E450-E457.
Saigal R, Lau D, Berven SH, Carreon L, Dekutoski MB, Kebaish KM, Qiu Y, Matsuyama Y, Kelly M, Dahl BT, Mehdian H, Pellisé F, Lewis SJ, Cheung KMC, Shaffrey CI, Fehlings MG, Lenke LG, Ames CP, AOSpine Knowledge Forum Deformity. PMID: 33290376; PMCID: PMC8677606.
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Translation:
Humans
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In Reply to Letter to Editor Regarding "Economic Impact of COVID-19 on a High-Volume Academic Neurosurgical Practice". World Neurosurg. 2021 05; 149:278.
Sivakanthan S, Ko A, Saigal R. PMID: 33640530; PMCID: PMC7905380.
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Translation:
HumansCells
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2021 Young Investigator Award Winner: Anatomic Gradients in the Microbiology of Spinal Fusion Surgical Site Infection and Resistance to Surgical Antimicrobial Prophylaxis. Spine (Phila Pa 1976). 2021 Feb 01; 46(3):143-151.
Long DR, Bryson-Cahn C, Pergamit R, Tavolaro C, Saigal R, Chan JD, Lynch JB. PMID: 32796459; PMCID: PMC8299899.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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The Dancing Cord: Inherent Spinal Cord Motion and Its Effect on Cord Dose in Spine Stereotactic Body Radiation Therapy. Neurosurgery. 2020 11 16; 87(6):1157-1166.
Oztek MA, Mayr NA, Mossa-Basha M, Nyflot M, Sponseller PA, Wu W, Hofstetter CP, Saigal R, Bowen SR, Hippe DS, Yuh WTC, Stewart RD, Lo SS. PMID: 32497210; PMCID: PMC8184298.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Commentary: Mature Imaging-Based Outcomes Supporting Local Control for Complex Reirradiation Salvage Spine Stereotactic Body Radiotherapy. Neurosurgery. 2020 09 15; 87(4):E498-E499.
Vellayappan BA, Foote M, Chang EL, Suh JH, Saigal R, Hofstetter CP, Lo SS. PMID: 32386215.
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Translation:
Humans
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Anterior Column Realignment: Analysis of Neurological Risk and Radiographic Outcomes. Neurosurgery. 2020 09 01; 87(3):E347-E354.
Saigal R, Akbarnia BA, Eastlack RK, Bagheri A, Tran S, Brown D, Bagheri R, Mundis GM. PMID: 32297951.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold. JAMA Neurol. 2020 09 01; 77(9):1150-1158.
Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann L, Saigal R, Ding Q, Hirschi R, Zeiler FA, Ferguson AR, Manley GT. PMID: 32539101; PMCID: PMC7296460.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Economic Impact of COVID-19 on a High-Volume Academic Neurosurgical Practice. World Neurosurg. 2020 11; 143:e561-e566.
Sivakanthan S, Pan J, Kim L, Ellenbogen R, Saigal R. PMID: 32791222; PMCID: PMC7416742.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Commentary: Local Control and Toxicity of Multilevel Spine Stereotactic Body Radiotherapy. Neurosurgery. 2020 02 01; 86(2):E173-E174.
Dunne EM, Liu M, Hofstetter C, Saigal R, Lo SS. PMID: 31628748.
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Translation:
Humans
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Commentary: Postoperative Stereotactic Body Radiotherapy for Spinal Metastases and the Impact of Epidural Disease Grade. Neurosurgery. 2020 01 01; 86(1):E91-E92.
Vellayappan B, Kumar N, Foote M, Hofstetter CP, Saigal R, Chao ST, Lo SS. PMID: 31595964.
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Translation:
Humans
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Strategies to Mitigate Toxicities From Stereotactic Body Radiation Therapy for Spine Metastases. Neurosurgery. 2019 12 01; 85(6):729-740.
Schaub SK, Tseng YD, Chang EL, Sahgal A, Saigal R, Hofstetter CP, Foote M, Ko AL, Yuh WTC, Mossa-Basha M, Mayr NA, Lo SS. PMID: 31264703.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Enhanced perioperative care and decreased cost and length of stay after elective major spinal surgery. Neurosurg Focus. 2019 04 01; 46(4):E5.
Carr DA, Saigal R, Zhang F, Bransford RJ, Bellabarba C, Dagal A. PMID: 30933922.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Stereotactic body radiotherapy for benign spinal tumors: Meningiomas, schwannomas, and neurofibromas. J Radiosurg SBRT. 2019; 6(3):167-177.
Hwang L, Okoye CC, Patel RB, Sahgal A, Foote M, Redmond KJ, Hofstetter C, Saigal R, Mossa-Basha M, Yuh W, Mayr NA, Chao ST, Chang EL, Lo SS. PMID: 31998537; PMCID: PMC6774487.
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PubMed Mentions:
3
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Analysis of high-frequency PbtO2 measures in traumatic brain injury: insights into the treatment threshold. J Neurosurg. 2019 10 01; 131(4):1216-1226.
Hirschi R, Hawryluk GWJ, Nielson JL, Huie JR, Zimmermann LL, Saigal R, Ding Q, Ferguson AR, Manley G. PMID: 30497191; PMCID: PMC8979548.
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PubMed Mentions:
10 Fields:
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Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 Nov; 79(5):708-714.
Readdy WJ, Saigal R, Whetstone WD, Mefford AN, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. PMID: 27759678.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Higher Mean Arterial Pressure Values Correlate with Neurologic Improvement in Patients with Initially Complete Spinal Cord Injuries. World Neurosurg. 2016 Dec; 96:72-79.
Catapano JS, John Hawryluk GW, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. PMID: 27565460; PMCID: PMC5127746.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Anterior Column Realignment (ACR) in Adult Sagittal Deformity Correction: Technique and Review of the Literature. Spine (Phila Pa 1976). 2016 Apr; 41 Suppl 8:S66-73.
Saigal R, Mundis GM, Eastlack R, Uribe JS, Phillips FM, Akbarnia BA. PMID: 26839994.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
75 Fields:
Translation:
Humans
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Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome. J Neurosurg Spine. 2015 Nov; 23(5):574-580.
Readdy WJ, Whetstone WD, Ferguson AR, Talbott JF, Inoue T, Saigal R, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Dhall SS. PMID: 26230417.
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PubMed Mentions:
15 Fields:
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Adult Spinal Deformity Patients Recall Fewer Than 50% of the Risks Discussed in the Informed Consent Process Preoperatively and the Recall Rate Worsens Significantly in the Postoperative Period. Spine (Phila Pa 1976). 2015 Jul 15; 40(14):1079-85.
Saigal R, Clark AJ, Scheer JK, Smith JS, Bess S, Mummaneni PV, McCarthy IM, Hart RA, Kebaish KM, Klineberg EO, Deviren V, Schwab F, Shaffrey CI, Ames CP. PMID: 25946720.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015 Oct; 23(4):495-504.
Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. PMID: 26161519.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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The long-term effects of repetitive mild head injuries in sports. Neurosurgery. 2014 Oct; 75 Suppl 4:S149-55.
Saigal R, Berger MS. PMID: 25232880.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Return to play for neurosurgical patients. World Neurosurg. 2014 Sep-Oct; 82(3-4):485-91.
Saigal R, Batjer HH, Ellenbogen RG, Berger MS. PMID: 25043128.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Unilateral versus bilateral iliac screws for spinopelvic fixation: are two screws better than one? Neurosurg Focus. 2014 May; 36(5):E10.
Saigal R, Lau D, Wadhwa R, Le H, Khashan M, Berven S, Chou D, Mummaneni PV. PMID: 24785475.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Minimally invasive extracavitary transpedicular corpectomy for the management of spinal tumors. Neurosurg Clin N Am. 2014 Apr; 25(2):305-15.
Saigal R, Wadhwa R, Mummaneni PV, Chou D. PMID: 24703448.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Conversion of high sacral to midsacral amputation via S-2 nerve preservation during partial S-2 sacrectomy for chordoma. J Neurosurg Spine. 2014 Apr; 20(4):421-9.
Saigal R, Lu DC, Deng DY, Chou D. PMID: 24527829.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Analysis of the direct cost of surgery for four diagnostic categories of adult spinal deformity. Spine J. 2013 Dec; 13(12):1843-8.
McCarthy IM, Hostin RA, O'Brien MF, Fleming NS, Ogola G, Kudyakov R, Richter KM, Saigal R, Berven SH, Ames CP, International Spine Study Group. PMID: 24315558.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Targeted reduction in neurosurgical laboratory utilization: resident-led effort at a single academic institution. J Neurosurg. 2014 Jan; 120(1):173-7.
Han SJ, Saigal R, Rolston JD, Cheng JS, Lau CY, Mistry RI, McDermott MW, Berger MS. PMID: 24125592.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Cost-Effectiveness of Surgical Treatment for Adult Spinal Deformity: A Comparison of Dollars per Quality of Life Improvement Across Health Domains. Spine Deform. 2013 Jul; 1(4):293-298.
McCarthy I, Hostin R, O'Brien M, Fleming N, Ogola G, Kudyakov R, Richter K, Saigal R, Berven S, Deviren V, Ames C, International Spine Study Group. PMID: 27927361.
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PubMed Mentions:
1 Fields:
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Health economic analysis of adult deformity surgery. Neurosurg Clin N Am. 2013 Apr; 24(2):293-304.
McCarthy I, Hostin R, O'Brien M, Saigal R, Ames CP. PMID: 23561565.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Electrical stimulation via a biocompatible conductive polymer directs retinal progenitor cell differentiation. Annu Int Conf IEEE Eng Med Biol Soc. 2013; 2013:1627-31.
Saigal R, Cimetta E, Tandon N, Zhou J, Langer R, Young M, Vunjak-Novakovic G, Redenti S. PMID: 24110015; PMCID: PMC4480863.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Three-dimensional conductive constructs for nerve regeneration. J Biomed Mater Res A. 2009 Nov; 91(2):519-27.
George PM, Saigal R, Lawlor MW, Moore MJ, LaVan DA, Marini RP, Selig M, Makhni M, Burdick JA, Langer R, Kohane DS. PMID: 18985787.
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PubMed Mentions:
17 Fields:
Translation:
Animals
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Effects of electrical stimulation in C2C12 muscle constructs. J Tissue Eng Regen Med. 2008 Jul; 2(5):279-87.
Park H, Bhalla R, Saigal R, Radisic M, Watson N, Langer R, Vunjak-Novakovic G. PMID: 18512267; PMCID: PMC2782921.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Locomotor-related networks in the lumbosacral enlargement of the adult spinal cat: activation through intraspinal microstimulation. IEEE Trans Neural Syst Rehabil Eng. 2006 Sep; 14(3):266-72.
Guevremont L, Renzi CG, Norton JA, Kowalczewski J, Saigal R, Mushahwar VK. PMID: 17009485.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Could cortical signals control intraspinal stimulators? A theoretical evaluation. IEEE Trans Neural Syst Rehabil Eng. 2006 Jun; 14(2):198-201.
Mushahwar VK, Guevremont L, Saigal R. PMID: 16792293.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Motor neuron firing dysfunction in spastic patients with primary lateral sclerosis. J Neurophysiol. 2005 Aug; 94(2):919-27.
Floeter MK, Zhai P, Saigal R, Kim Y, Statland J. PMID: 15829597; PMCID: PMC1360205.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Intraspinal microstimulation generates functional movements after spinal-cord injury. IEEE Trans Neural Syst Rehabil Eng. 2004 Dec; 12(4):430-40.
Saigal R, Renzi C, Mushahwar VK. PMID: 15614999.
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PubMed Mentions:
43 Fields:
Translation:
Animals
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The somatotopic arrangement of motor neurons in the spinal cord of buffalo (Bubalus bubalis). B. Lumbosacral plexus. Acta Anat (Basel). 1972; 81(1):102-7.
Rao GS, Saigal RP, Sahu S. PMID: 5027065.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells