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Zhonghui Guan, MD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
DepartmentAnesthesia
Address513 Parnassus Avenue
San Francisco CA 94117
Phone415-885-7246
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    Collapse Biography 
    Collapse Education and Training
    UCSF, San Francisco, CA08/2009Clinical Pain Fellow
    Massachusetts General Hospital, Boston, MA08/2008Anesthesia Resident
    Columbia University, New York, NY07/2004Associate Research Scientist
    National Institute of Health (NIH), Bethesda, MD04/1999Postdoctoral Research Scientist
    Peking Union Medical College (PUMC), Beijing, ChinaMD07/1994Medicine
    Collapse Awards and Honors
    U.S. News & World Report2012Top Doctor in Pain Management

    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of Nerve Injury-induced Gene Expression in Neuropathic Pain
    NIH R01NS100801Jul 1, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Epigenetic regulation in neuropathic pain
    NIH K08NS078050Sep 30, 2012 - Aug 31, 2017
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Guan Z, Hellman J, Schumacher M. Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. F1000Res. 2016; 5. PMID: 27781082.
      View in: PubMed
    2. Guan Z, Kuhn JA, Wang X, Colquitt B, Solorzano C, Vaman S, Guan AK, Evans-Reinsch Z, Braz J, Devor M, Abboud-Werner SL, Lanier LL, Lomvardas S, Basbaum AI. Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain. Nat Neurosci. 2016 Jan; 19(1):94-101. PMID: 26642091; PMCID: PMC4703328.
    3. Bráz JM, Wang X, Guan Z, Rubenstein JL, Basbaum AI. Transplant-mediated enhancement of spinal cord GABAergic inhibition reverses paclitaxel-induced mechanical and heat hypersensitivity. Pain. 2015 Jun; 156(6):1084-91. PMID: 25760475.
      View in: PubMed
    4. Solorzano C, Villafuerte D, Meda K, Cevikbas F, Bráz J, Sharif-Naeini R, Juarez-Salinas D, Llewellyn-Smith IJ, Guan Z, Basbaum AI. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci. 2015 Jan 14; 35(2):648-57. PMID: 25589759.
      View in: PubMed
    5. Guan Z, Baker K, Sandberg WS. Misalignment of disposable pulse oximeter probes results in false saturation readings that influence anesthetic management. Anesth Analg. 2009 Nov; 109(5):1530-3. PMID: 19843792.
      View in: PubMed
    6. Yu JX, Guan Z, Nash HA. The mushroom body defect gene product is an essential component of the meiosis II spindle apparatus in Drosophila oocytes. Genetics. 2006 May; 173(1):243-53. PMID: 16510791; PMCID: PMC1461445.
    7. Levine AA, Guan Z, Barco A, Xu S, Kandel ER, Schwartz JH. CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):19186-91. PMID: 16380431; PMCID: PMC1323217.
    8. Guan Z, Kim JH, Lomvardas S, Holick K, Xu S, Kandel ER, Schwartz JH. p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia. J Neurosci. 2003 Aug 13; 23(19):7317-25. PMID: 12917365.
      View in: PubMed
    9. Guan Z, Giustetto M, Lomvardas S, Kim JH, Miniaci MC, Schwartz JH, Thanos D, Kandel ER. Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure. Cell. 2002 Nov 15; 111(4):483-93. PMID: 12437922.
      View in: PubMed
    10. Guan Z, Prado A, Melzig J, Heisenberg M, Nash HA, Raabe T. Mushroom body defect, a gene involved in the control of neuroblast proliferation in Drosophila, encodes a coiled-coil protein. Proc Natl Acad Sci U S A. 2000 Jul 05; 97(14):8122-7. PMID: 10884435; PMCID: PMC16680.
    11. Guan Z, Scott RL, Nash HA. A new assay for the genetic study of general anesthesia in Drosophila melanogaster: use in analysis of mutations in the X-chromosomal 12E region. J Neurogenet. 2000 Apr; 14(1):25-42. PMID: 10938546.
      View in: PubMed