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Xiangning Jiang, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
Phone415-502-1099
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of brain cholesterol homeostasis following neonatal hypoxia-ischemia
    NIH R56NS114563Aug 1, 2020 - Jul 31, 2021
    Role: Principal Investigator
    Phospho-regulation of NMDA receptors in neonatal brain hypoxia-ischemia
    NIH R01NS084057Mar 15, 2014 - Feb 29, 2020
    Role: Principal Investigator
    Src Family Kinases - Mediated Ischemic Neonatal Brain Injury
    NIH R21NS059613Jun 1, 2009 - May 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Serum 24S-hydroxycholesterol predicts long-term brain structural and functional outcomes after hypoxia-ischemia in neonatal mice. J Cereb Blood Flow Metab. 2020 Mar 13; 271678X20911910. Lu F, Fan S, Romo AR, Xu D, Ferriero DM, Jiang X. PMID: 32169014.
      View in: PubMed   Mentions: 1     Fields:    
    2. Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling. Sci Rep. 2018 11 30; 8(1):17522. Minnella AM, Zhao JX, Jiang X, Jakobsen E, Lu F, Wu L, El-Benna J, Gray JA, Swanson RA. PMID: 30504838.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Upregulation of cholesterol 24-hydroxylase following hypoxia-ischemia in neonatal mouse brain. Pediatr Res. 2018 06; 83(6):1218-1227. Lu F, Zhu J, Guo S, Wong BJ, Chehab FF, Ferriero DM, Jiang X. PMID: 29718007.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. Hypoxia-ischemia modifies postsynaptic GluN2B-containing NMDA receptor complexes in the neonatal mouse brain. Exp Neurol. 2018 01; 299(Pt A):65-74. Lu F, Shao G, Wang Y, Guan S, Burlingame AL, Liu X, Liang X, Knox R, Ferriero DM, Jiang X. PMID: 28993251.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    5. Cellular and molecular introduction to brain development. Neurobiol Dis. 2016 08; 92(Pt A):3-17. Jiang X, Nardelli J. PMID: 26184894.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    6. Isolating astrocytes and neurons sequentially from postnatal murine brains with a magnetic cell separation technique. Journal of Biological Methods. 2014 Nov 29; 1(2):11. Maria Feldmann, Praneeti Pathipati, R Ann Sheldon, Xiangning Jiang, Donna M Ferriero. .
      View in: Publisher Site   Mentions:
    7. NR2B phosphorylation at tyrosine 1472 contributes to brain injury in a rodent model of neonatal hypoxia-ischemia. Stroke. 2014 Oct; 45(10):3040-7. Knox R, Brennan-Minnella AM, Lu F, Yang D, Nakazawa T, Yamamoto T, Swanson RA, Ferriero DM, Jiang X. PMID: 25158771.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    8. Hypoxic preconditioning protection is eliminated in HIF-1a knockout mice subjected to neonatal hypoxia-ischemia. Pediatr Res. 2014 Jul; 76(1):46-53. Sheldon RA, Lee CL, Jiang X, Knox RN, Ferriero DM. PMID: 24713818.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    9. FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2a at the CYP51 promoter. J Lipid Res. 2014 Mar; 55(3):431-42. Zhu J, Jiang X, Chehab FF. PMID: 24353279.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Phenotype and secretory responses to oxidative stress in microglia. Dev Neurosci. 2013; 35(2-3):241-54. Pathipati P, Müller S, Jiang X, Ferriero D. PMID: 23548608.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    11. Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia-ischemia in mice with neuronal Fyn overexpression. Neurobiol Dis. 2013 Mar; 51:113-9. Knox R, Zhao C, Miguel-Perez D, Wang S, Yuan J, Ferriero D, Jiang X. PMID: 23127881.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    12. Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain. Neurosci Lett. 2011 Oct 10; 503(3):215-9. Jiang X, Knox R, Pathipati P, Ferriero D. PMID: 21896318.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. Role of vasodilator stimulated phosphoprotein in VEGF induced blood-brain barrier permeability in endothelial cell monolayers. Int J Dev Neurosci. 2010 Oct; 28(6):423-8. Davis B, Tang J, Zhang L, Mu D, Jiang X, Biran V, Vexler Z, Ferriero DM. PMID: 20599605.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    14. HIF-1 alpha-deficient mice have increased brain injury after neonatal hypoxia-ischemia. Dev Neurosci. 2009; 31(5):452-8. Sheldon RA, Osredkar D, Lee CL, Jiang X, Mu D, Ferriero DM. PMID: 19672073.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    15. Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons. Neurosci Lett. 2008 Aug 15; 441(1):134-8. Chang S, Jiang X, Zhao C, Lee C, Ferriero DM. PMID: 18597936.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    16. Activated Src kinases interact with the N-methyl-D-aspartate receptor after neonatal brain ischemia. Ann Neurol. 2008 May; 63(5):632-41. Jiang X, Mu D, Biran V, Faustino J, Chang S, Rincón CM, Sheldon RA, Ferriero DM. PMID: 18384166.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    17. A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection. Neurosci Lett. 2005 May 06; 379(2):96-100. Hamrick SE, McQuillen PS, Jiang X, Mu D, Madan A, Ferriero DM. PMID: 15823423.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    18. Differential vulnerability of immature murine neurons to oxygen-glucose deprivation. Exp Neurol. 2004 Nov; 190(1):224-32. Jiang X, Mu D, Manabat C, Koshy AA, Christen S, Täuber MG, Vexler ZS, Ferriero DM. PMID: 15473995.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    19. Manipulation of antioxidant pathways in neonatal murine brain. Pediatr Res. 2004 Oct; 56(4):656-62. Sheldon RA, Jiang X, Francisco C, Christen S, Vexler ZS, Täuber MG, Ferriero DM. PMID: 15295091.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    20. Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model. Neurobiol Dis. 2003 Dec; 14(3):524-34. Mu D, Jiang X, Sheldon RA, Fox CK, Hamrick SE, Vexler ZS, Ferriero DM. PMID: 14678768.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    21. Neonatal hypoxia-ischemia differentially upregulates MAGUKs and associated proteins in PSD-93-deficient mouse brain. Stroke. 2003 Dec; 34(12):2958-63. Jiang X, Mu D, Sheldon RA, Glidden DV, Ferriero DM. PMID: 14605317.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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