Nikolaos Kyritsis, PhD

Title(s)Assistant Professor, Neurological Surgery
SchoolSchool of Medicine
Address2540 23rd Street, #3707
San Francisco CA 94110
ORCID ORCID Icon0000-0001-7801-5796 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Ioannina, Ioannina, GreeceBSc/MSc2009Biology
    International Max Planck Research School/ TU Dresden, Dresden, GermanyPh.D.2013Molecular Neurobiology
    University of California San Francisco (UCSF), San Francisco, USAPostdoc2020Spinal Cord Injury
    University of California, San Francisco, CA06/2022Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Leonidas Charalambous-Kolokythas Scholarship Foundation2009Scholarship for studies abroad
    EMBO2012Travel Grant for the Conference "The molecular and cellular basis of regeneration and tissue repair"
    DIGS-BB2013Travel Grant to Abcam Meeting “New Avenues for Brain Repair: Programming and Reprogramming the CNS"
    Berlin-Brandenburg School for Regenerative Medicine (BSRT)2013PhD student award in Regenerative Medicine for the most outstanding publication
    CRTD e.V. (friends and donors of CRTD)2014Award for the best PhD thesis in 2013
    EMBO2015  - 2017EMBO Long Term Fellowship
    ISNR2015Travel Grant for the International Symposium for Neural Regeneration
    Wings for Life2018  - 2020Individual Grant from Wings for Life
    Wings for Life2019Best Poster Award at the Wings for Life Annual Meeting
    ISNR2020Best Poster Award at the International Symposium for Neural Regeneration
    Wings for Life2020  - 2021Individual Grant from Wings for Life (extension)

    Collapse Overview 
    Collapse Overview
    Molecular neuroscientist with a great interest in traumatic spinal cord (mostly) and brain injuries and the use of high throughput big data analytics for biomarker discovery and functional interventions.

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    Collapse Featured Publications

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. ATF3 is a neuron-specific biomarker for spinal cord injury and ischaemic stroke. Clin Transl Med. 2024 Apr; 14(4):e1650. Pan JZ, Wang Z, Sun W, Pan P, Li W, Sun Y, Chen S, Lin A, Tan W, He L, Greene J, Yao V, An L, Liang R, Li Q, Yu J, Zhang L, Kyritsis N, Fernandez XD, Moncivais S, Mendoza E, Fung P, Wang G, Niu X, Du Q, Xiao Z, Chang Y, Lv P, Huie JR, Torres-Espin A, Ferguson AR, Hemmerle DD, Talbott JF, Weinstein PR, Pascual LU, Singh V, DiGiorgio AM, Saigal R, Whetstone WD, Manley GT, Dhall SS, Bresnahan JC, Maze M, Jiang X, Singhal NS, Beattie MS, Su H, Guan Z. PMID: 38649772; PMCID: PMC11035380.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Hypotension requiring vasopressor treatment and increased cardiac complications in elderly spinal cord injury patients: a prospective TRACK-SCI registry study. J Neurosurg Spine. 2023 Mar 17; 1-9. Agarwal N, Blitstein J, Lui A, Torres-Espin A, Vasnarungruengkul C, Burke J, Mummaneni PV, Dhall SS, Weinstein PR, Duong-Fernandez X, Chou A, Pan J, Singh V, Ferguson AR, Hemmerle DD, Kyritsis N, Talbott JF, Whetstone WD, Bresnahan JC, Beattie MS, Manley GT, DiGiorgio A. PMID: 36933260.
      View in: PubMed   Mentions:    Fields:    
    3. Expert-augmented automated machine learning optimizes hemodynamic predictors of spinal cord injury outcome. PLoS One. 2022; 17(4):e0265254. Chou A, Torres-Espin A, Kyritsis N, Huie JR, Khatry S, Funk J, Hay J, Lofgreen A, Shah R, McCann C, Pascual LU, Amorim E, Weinstein PR, Manley GT, Dhall SS, Pan JZ, Bresnahan JC, Beattie MS, Whetstone WD, Ferguson AR, TRACK-SCI Investigators. PMID: 35390006; PMCID: PMC8989303.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    4. Decision tree-based machine learning analysis of intraoperative vasopressor use to optimize neurological improvement in acute spinal cord injury. Neurosurg Focus. 2022 04; 52(4):E9. Agarwal N, Aabedi AA, Torres-Espin A, Chou A, Wozny TA, Mummaneni PV, Burke JF, Ferguson AR, Kyritsis N, Dhall SS, Weinstein PR, Duong-Fernandez X, Pan J, Singh V, Hemmerle DD, Talbott JF, Whetstone WD, Bresnahan JC, Manley GT, Beattie MS, DiGiorgio AM. PMID: 35364586.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Appendicular Fracture and Polytrauma Correlate with Outcome of Spinal Cord Injury: A Transforming Research and Clinical Knowledge in Spinal Cord Injury Study. J Neurotrauma. 2022 08; 39(15-16):1030-1038. Miclau TA, Torres-Espin A, Morshed S, Morioka K, Huie JR, El Naga AN, Chou A, Pascual L, Duong-Fernandez X, Kuo YH, Weinstein P, Dhall SS, Bresnahan JC, Beattie MS, Digiorgio A, Ferguson AR, Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI) Investigators. PMID: 35255740; PMCID: PMC9536347.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury. Elife. 2021 11 16; 10. Torres-Espín A, Haefeli J, Ehsanian R, Torres D, Almeida CA, Huie JR, Chou A, Morozov D, Sanderson N, Dirlikov B, Suen CG, Nielson JL, Kyritsis N, Hemmerle DD, Talbott JF, Manley GT, Dhall SS, Whetstone WD, Bresnahan JC, Beattie MS, McKenna SL, Pan JZ, Ferguson AR, TRACK-SCI Investigators. PMID: 34783309; PMCID: PMC8639149.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    7. Diagnostic blood RNA profiles for human acute spinal cord injury. J Exp Med. 2021 03 01; 218(3). Kyritsis N, Torres-Espín A, Schupp PG, Huie JR, Chou A, Duong-Fernandez X, Thomas LH, Tsolinas RE, Hemmerle DD, Pascual LU, Singh V, Pan JZ, Talbott JF, Whetstone WD, Burke JF, DiGiorgio AM, Weinstein PR, Manley GT, Dhall SS, Ferguson AR, Oldham MC, Bresnahan JC, Beattie MS. PMID: 33512429; PMCID: PMC7852457.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    8. Machine intelligence identifies soluble TNFa as a therapeutic target for spinal cord injury. Sci Rep. 2021 02 09; 11(1):3442. Huie JR, Ferguson AR, Kyritsis N, Pan JZ, Irvine KA, Nielson JL, Schupp PG, Oldham MC, Gensel JC, Lin A, Segal MR, Ratan RR, Bresnahan JC, Beattie MS. PMID: 33564058; PMCID: PMC7873211.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    9. Reproducible analysis of disease space via principal components using the novel R package syndRomics. Elife. 2021 01 14; 10. Torres-Espín A, Chou A, Huie JR, Kyritsis N, Upadhyayula PS, Ferguson AR. PMID: 33443012; PMCID: PMC7857733.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    10. Injury volume extracted from MRI predicts neurologic outcome in acute spinal cord injury: A prospective TRACK-SCI pilot study. J Clin Neurosci. 2020 Dec; 82(Pt B):231-236. Mummaneni N, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris M, Pascual LU, Ferguson AR, Russell Huie J, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, Kyritsis N, Weinstein PR, Whetstone WD, Manley GT, Bresnahan JC, Beattie MS, Cohen-Adad J, Dhall SS, Talbott JF. PMID: 33248950.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI): an overview of initial enrollment and demographics. Neurosurg Focus. 2020 05 01; 48(5):E6. Tsolinas RE, Burke JF, DiGiorgio AM, Thomas LH, Duong-Fernandez X, Harris MH, Yue JK, Winkler EA, Suen CG, Pascual LU, Ferguson AR, Huie JR, Pan JZ, Hemmerle DD, Singh V, Torres-Espin A, Omondi C, Kyritsis N, Haefeli J, Weinstein PR, de Almeida Neto CA, Kuo YH, Taggard D, Talbott JF, Whetstone WD, Manley GT, Bresnahan JC, Beattie MS, Dhall SS. PMID: 32357323.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    12. Clinical Implementation of Novel Spinal Cord Perfusion Pressure Protocol in Acute Traumatic Spinal Cord Injury at U.S. Level I Trauma Center: TRACK-SCI Study. World Neurosurg. 2020 Jan; 133:e391-e396. Yue JK, Hemmerle DD, Winkler EA, Thomas LH, Fernandez XD, Kyritsis N, Pan JZ, Pascual LU, Singh V, Weinstein PR, Talbott JF, Huie JR, Ferguson AR, Whetstone WD, Manley GT, Beattie MS, Bresnahan JC, Mummaneni PV, Dhall SS. PMID: 31526882.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    13. Convolutional Neural Network-Based Automated Segmentation of the Spinal Cord and Contusion Injury: Deep Learning Biomarker Correlates of Motor Impairment in Acute Spinal Cord Injury. AJNR Am J Neuroradiol. 2019 04; 40(4):737-744. McCoy DB, Dupont SM, Gros C, Cohen-Adad J, Huie RJ, Ferguson A, Duong-Fernandez X, Thomas LH, Singh V, Narvid J, Pascual L, Kyritsis N, Beattie MS, Bresnahan JC, Dhall S, Whetstone W, Talbott JF, TRACK-SCI Investigators. PMID: 30923086; PMCID: PMC7048524.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    14. Effects of inflammation on stem cells: together they strive? EMBO Rep. 2015 Apr; 16(4):416-26. Kizil C, Kyritsis N, Brand M. PMID: 25739812; PMCID: PMC4388609.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    15. Neuroinflammation and central nervous system regeneration in vertebrates. Trends Cell Biol. 2014 Feb; 24(2):128-35. Kyritsis N, Kizil C, Brand M. PMID: 24029244.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    16. Regenerative neurogenesis from neural progenitor cells requires injury-induced expression of Gata3. Dev Cell. 2012 Dec 11; 23(6):1230-7. Kizil C, Kyritsis N, Dudczig S, Kroehne V, Freudenreich D, Kaslin J, Brand M. PMID: 23168169.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    17. Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science. 2012 Dec 07; 338(6112):1353-6. Kyritsis N, Kizil C, Zocher S, Kroehne V, Kaslin J, Freudenreich D, Iltzsche A, Brand M. PMID: 23138980.
      View in: PubMed   Mentions: 237     Fields:    Translation:AnimalsCells
    18. The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain. Neural Dev. 2012 Jul 23; 7:27. Kizil C, Dudczig S, Kyritsis N, Machate A, Blaesche J, Kroehne V, Brand M. PMID: 22824261; PMCID: PMC3441421.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
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