Kristin Sellers, PhD

Title(s)Assistant Professor, Neurological Surgery
SchoolSchool of Medicine
Address1651 4th Street, #001
San Francisco CA 94158
PronounsShe/Her/Hers
ORCID ORCID Icon0000-0002-0517-2296 Additional info
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    Collapse Biography 
    Collapse education and training
    Cornell University, Ithaca, NYBS2011Human Development
    University of North Carolina, Chapel Hill Ph.D.2016Neurobiology
    University of North Carolina, Chapel HillCertificate2016Translational Medicine
    University of California, San FranciscoPostdoctoral Scholar2020Neurological Surgery

    Collapse Overview 
    Collapse overview
    Dr. Sellers is an Assistant Adjunct Professor in the Department of Neurological Surgery. She studies intracranial electrical stimulation for the treatment of neuropsychiatric disorders including major depressive disorder and chronic pain. She works to translate learnings from early stage clinical trials of closed-loop neuromodulation for the development of neurotechnologies and supporting infrastructure.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Best practices for clinical trials of deep brain stimulation for neuropsychiatric indications. Front Hum Neurosci. 2025; 19:1572972. Tremblay-McGaw AG, Hamlat EJ, Becker NC, Astudillo Maya DA, Krystal AD, Sellers KK. PMID: 40309667; PMCID: PMC12041084.
      View in: PubMed   Mentions:
    2. Invasive Brain Mapping Identifies Personalized Therapeutic Neuromodulation Targets for Obsessive-Compulsive Disorder. medRxiv. 2025 Mar 17. Lee AM, Kist A, Alvarez J, Sellers KK, Khambhati AN, Sugrue LP, Reid LB, Kadlec K, Fan JM, Allawala AB, Racine CA, Norbu T, Astudillo D, Tremblay-McGaw AG, Becker N, Alhourani A, Starr PA, Chang EF, Krystal AD. PMID: 40166548; PMCID: PMC11957075.
      View in: PubMed   Mentions:
    3. DREDge: robust motion correction for high-density extracellular recordings across species. Nat Methods. 2025 Apr; 22(4):788-800. Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan RT, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Elmaleh M, Christianson D, Greenlee JDW, Horváth C, Fiáth R, Ulbert I, Long MA, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E. PMID: 40050699.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    4. Large-scale single-neuron speech sound encoding across the depth of human cortex. Nature. 2024 Feb; 626(7999):593-602. Leonard MK, Gwilliams L, Sellers KK, Chung JE, Xu D, Mischler G, Mesgarani N, Welkenhuysen M, Dutta B, Chang EF. PMID: 38093008; PMCID: PMC10866713.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    5. DREDge: robust motion correction for high-density extracellular recordings across species. bioRxiv. 2023 Oct 29. Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan M, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Horváth C, Fiáth R, Ulbert I, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E. PMID: 37961359; PMCID: PMC10634799.
      View in: PubMed   Mentions: 1  
    6. Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder. J Vis Exp. 2023 07 07; (197). Sellers KK, Khambhati AN, Stapper N, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD. PMID: 37486114.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans. Brain Stimul. 2023 Jul-Aug; 16(4):1072-1082. Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD. PMID: 37385540; PMCID: PMC10634663.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Closed-loop neurostimulation for the treatment of psychiatric disorders. Neuropsychopharmacology. 2024 Jan; 49(1):163-178. Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD. PMID: 37369777; PMCID: PMC10700557.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations. Brain Stimul. 2023 Mar-Apr; 16(2):462-465. Fan JM, Khambhati AN, Sellers KK, Stapper N, Maya DA, Kunwar E, Henderson C, Sugrue LP, Scangos KW, Chang EF, Rao VR, Krystal AD. PMID: 36773780; PMCID: PMC10627048.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Changes in intracranial neurophysiology associated with acute COVID-19 infection. Clin Neurophysiol. 2023 04; 148:29-31. Sellers KK, Stapper N, Astudillo Maya DA, Henderson C, Khambhati AN, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD. PMID: 36791656; PMCID: PMC9896881.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. High-density single-unit human cortical recordings using the Neuropixels probe. Neuron. 2022 08 03; 110(15):2409-2421.e3. Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF. PMID: 35679860.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    12. Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain. Front Neurosci. 2021; 15:762097. Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P. PMID: 34975374; PMCID: PMC8716790.
      View in: PubMed   Mentions: 7  
    13. Closed-loop neuromodulation in an individual with treatment-resistant depression. Nat Med. 2021 10; 27(10):1696-1700. Scangos KW, Khambhati AN, Daly PM, Makhoul GS, Sugrue LP, Zamanian H, Liu TX, Rao VR, Sellers KK, Dawes HE, Starr PA, Krystal AD, Chang EF. PMID: 34608328; PMCID: PMC11219029.
      View in: PubMed   Mentions: 138     Fields:    Translation:Humans
    14. Thin-film microfabrication and intraoperative testing ofµECoG and iEEG depth arrays for sense and stimulation. J Neural Eng. 2021 08 18; 18(4). Sellers KK, Chung JE, Zhou J, Triplett MG, Dawes HE, Haque R, Chang EF. PMID: 34330113; PMCID: PMC10495194.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System. Front Hum Neurosci. 2021; 15:714256. Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA. PMID: 34322004; PMCID: PMC8312257.
      View in: PubMed   Mentions: 16  
    16. Bidirectional propagation of low frequency oscillations over the human hippocampal surface. Nat Commun. 2021 05 12; 12(1):2764. Kleen JK, Chung JE, Sellers KK, Zhou J, Triplett M, Lee K, Tooker A, Haque R, Chang EF. PMID: 33980852; PMCID: PMC8115072.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    17. Rapid deployment of SARS-CoV-2 testing: The CLIAHUB. PLoS Pathog. 2020 10; 16(10):e1008966. Crawford ED, Acosta I, Ahyong V, Anderson EC, Arevalo S, Asarnow D, Axelrod S, Ayscue P, Azimi CS, Azumaya CM, Bachl S, Bachmutsky I, Bhaduri A, Brown JB, Batson J, Behnert A, Boileau RM, Bollam SR, Bonny AR, Booth D, Borja MJB, Brown D, Buie B, Burnett CE, Byrnes LE, Cabral KA, Cabrera JP, Caldera S, Canales G, Castañeda GR, Chan AP, Chang CR, Charles-Orszag A, Cheung C, Chio U, Chow ED, Citron YR, Cohen A, Cohn LB, Chiu C, Cole MA, Conrad DN, Constantino A, Cote A, Crayton-Hall T, Darmanis S, Detweiler AM, Dial RL, Dong S, Duarte EM, Dynerman D, Egger R, Fanton A, Frumm SM, Fu BXH, Garcia VE, Garcia J, Gladkova C, Goldman M, Gomez-Sjoberg R, Gordon MG, Grove JCR, Gupta S, Haddjeri-Hopkins A, Hadley P, Haliburton J, Hao SL, Hartoularos G, Herrera N, Hilberg M, Ho KYE, Hoppe N, Hosseinzadeh S, Howard CJ, Hussmann JA, Hwang E, Ingebrigtsen D, Jackson JR, Jowhar ZM, Kain D, Kim JYS, Kistler A, Kreutzfeld O, Kulsuptrakul J, Kung AF, Langelier C, Laurie MT, Lee L, Leng K, Leon KE, Leonetti MD, Levan SR, Li S, Li AW, Liu J, Lubin HS, Lyden A, Mann J, Mann S, Margulis G, Marquez DM, Marsh BP, Martyn C, McCarthy EE, McGeever A, Merriman AF, Meyer LK, Miller S, Moore MK, Mowery CT, Mukhtar T, Mwakibete LL, Narez N, Neff NF, Osso LA, Oviedo D, Peng S, Phelps M, Phong K, Picard P, Pieper LM, Pincha N, Pisco AO, Pogson A, Pourmal S, Puccinelli RR, Puschnik AS, Rackaityte E, Raghavan P, Raghavan M, Reese J, Replogle JM, Retallack H, Reyes H, Rose D, Rosenberg MF, Sanchez-Guerrero E, Sattler SM, Savy L, See SK, Sellers KK, Serpa PH, Sheehy M, Sheu J, Silas S, Streithorst JA, Strickland J, Stryke D, Sunshine S, Suslow P, Sutanto R, Tamura S, Tan M, Tan J, Tang A, Tato CM, Taylor JC, Tenvooren I, Thompson EM, Thornborrow EC, Tse E, Tung T, Turner ML, Turner VS, Turnham RE, Turocy MJ, Vaidyanathan TV, Vainchtein ID, Vanaerschot M, Vazquez SE, Wandler AM, Wapniarski A, Webber JT, Weinberg ZY, Westbrook A, Wong AW, Wong E, Worthington G, Xie F, Xu A, Yamamoto T, Yang Y, Yarza F, Zaltsman Y, Zheng T, DeRisi JL. PMID: 33112933; PMCID: PMC7592773.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsPHPublic Health
    18. A Deep Brain Stimulation Trial Period for Treating Chronic Pain. J Clin Med. 2020 Sep 29; 9(10). Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF. PMID: 33003443; PMCID: PMC7600449.
      View in: PubMed   Mentions: 6  
    19. Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy. J Neuropsychiatry Clin Neurosci. 2020; 32(2):185-190. Scangos KW, Ahmad HS, Shafi A, Sellers KK, Dawes HE, Krystal A, Chang EF. PMID: 31394989; PMCID: PMC7429560.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression. Curr Biol. 2018 12 17; 28(24):3893-3902.e4. Rao VR, Sellers KK, Wallace DL, Lee MB, Bijanzadeh M, Sani OG, Yang Y, Shanechi MM, Dawes HE, Chang EF. PMID: 30503621.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    21. Theta Oscillations Organize Spiking Activity in Higher-Order Visual Thalamus during Sustained Attention. eNeuro. 2018 Jan-Feb; 5(1). Yu C, Li Y, Stitt IM, Zhou ZC, Sellers KK, Frohlich F. PMID: 29619407; PMCID: PMC5881415.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Early Development of Network Oscillations in the Ferret Visual Cortex. Sci Rep. 2017 12 19; 7(1):17766. Li Y, Yu C, Zhou ZC, Stitt I, Sellers KK, Gilmore JH, Frohlich F. PMID: 29259184; PMCID: PMC5736753.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    23. Breakdown of local information processing may underlie isoflurane anesthesia effects. PLoS Comput Biol. 2017 Jun; 13(6):e1005511. Wollstadt P, Sellers KK, Rudelt L, Priesemann V, Hutt A, Fröhlich F, Wibral M. PMID: 28570661; PMCID: PMC5453425.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    24. Oscillatory Dynamics in the Frontoparietal Attention Network during Sustained Attention in the Ferret. Cell Rep. 2016 09 13; 16(11):2864-2874. Sellers KK, Yu C, Zhou ZC, Stitt I, Li Y, Radtke-Schuller S, Alagapan S, Fröhlich F. PMID: 27626658; PMCID: PMC5024719.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    25. Resting state network topology of the ferret brain. Neuroimage. 2016 12; 143:70-81. Zhou ZC, Salzwedel AP, Radtke-Schuller S, Li Y, Sellers KK, Gilmore JH, Shih YY, Fröhlich F, Gao W. PMID: 27596024; PMCID: PMC5124532.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    26. Dorso-Lateral Frontal Cortex of the Ferret Encodes Perceptual Difficulty during Visual Discrimination. Sci Rep. 2016 Mar 30; 6:23568. Zhou ZC, Yu C, Sellers KK, Fröhlich F. PMID: 27025995; PMCID: PMC4812342.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    27. Statistical Frequency-Dependent Analysis of Trial-to-Trial Variability in Single Time Series by Recurrence Plots. Front Syst Neurosci. 2015; 9:184. Tošic T, Sellers KK, Fröhlich F, Fedotenkova M, Beim Graben P, Hutt A. PMID: 26834580; PMCID: PMC4712310.
      View in: PubMed   Mentions: 3  
    28. Structural and functional connectivity between the lateral posterior-pulvinar complex and primary visual cortex in the ferret. Eur J Neurosci. 2016 Jan; 43(2):230-44. Yu C, Sellers KK, Radtke-Schuller S, Lu J, Xing L, Ghukasyan V, Li Y, Shih YY, Murrow R, Fröhlich F. PMID: 26505737; PMCID: PMC4718862.
      View in: PubMed   Mentions: 9  Translation:AnimalsCells
    29. Anesthesia-related changes in information transfer may be caused by reduction in local information generation. Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug; 2015:4045-8. Wollstadt P, Sellers KK, Hutt A, Frohlich F, Wibral M. PMID: 26737182.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Transcranial direct current stimulation (tDCS) of frontal cortex decreases performance on the WAIS-IV intelligence test. Behav Brain Res. 2015 Sep 01; 290:32-44. Sellers KK, Mellin JM, Lustenberger CM, Boyle MR, Lee WH, Peterchev AV, Fröhlich F. PMID: 25934490; PMCID: PMC4447535.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    31. Awake vs. anesthetized: layer-specific sensory processing in visual cortex and functional connectivity between cortical areas. J Neurophysiol. 2015 Jun 01; 113(10):3798-815. Sellers KK, Bennett DV, Hutt A, Williams JH, Fröhlich F. PMID: 25833839; PMCID: PMC4473519.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    32. Targeting the neurophysiology of cognitive systems with transcranial alternating current stimulation. Expert Rev Neurother. 2015 Feb; 15(2):145-67. Fröhlich F, Sellers KK, Cordle AL. PMID: 25547149; PMCID: PMC4634940.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    33. Frequency-band signatures of visual responses to naturalistic input in ferret primary visual cortex during free viewing. Brain Res. 2015 Feb 19; 1598:31-45. Sellers KK, Bennett DV, Fröhlich F. PMID: 25498982; PMCID: PMC4339449.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    34. Anesthesia differentially modulates spontaneous network dynamics by cortical area and layer. J Neurophysiol. 2013 Dec; 110(12):2739-51. Sellers KK, Bennett DV, Hutt A, Fröhlich F. PMID: 24047911.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    35. Transcranial alternating current stimulation modulates large-scale cortical network activity by network resonance. J Neurosci. 2013 Jul 03; 33(27):11262-75. Ali MM, Sellers KK, Fröhlich F. PMID: 23825429; PMCID: PMC6618612.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansAnimals
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