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Ngoc Ly, MD, MPH

TitleProfessor
SchoolUCSF School of Medicine
DepartmentPediatrics
Address550 16th. Street
San Francisco CA 94158
Phone415-476-4979
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    Collapse Biography 
    Collapse Education and Training
    University of RochesterM.D.1998School of Medicine
    Medical College of VirginiaPediatric Residency2001Pediatrics
    Harvard School of Public HealthMPH2004Public Health
    Massachusetts General Hospital and Harvard Medical SchoolPediatric Pulmonary Fellowship2004Pediatrics
    Brigham & Women's Hospital and Harvard School of MedicineRespiratory and Environmental Epidemiology2006Channing Laboratory
    Collapse Awards and Honors
    UCSF2014Faculty Mentorship Award, Fellows Leadership Advocacy Group (FLAG)

    Collapse Overview 
    Collapse Overview
    My research has focused on the influences of heredity, as well as prenatal and infant environmental exposures ( including environmental, microbial, and nutritional influences) on immune responses and clinical symptoms of allergy and asthma. I have been actively involved and collaborated with investigators on 4 large prospective birth cohort studies and a cross-sectional study relating to environmental and immunological determinants of allergy and asthma.

    Clinically, I oversee and direct care for a large number of asthmatic children in the Pediatric Pulmonary Asthma Program at UCSF that I established in 2009. The Asthma Program consists of an asthma care team that includes a nurse practitioner and respiratory therapist certified in asthma education to facilitate asthma education and management for children less than 18 years of age.

    My other clinical interests include bronchopulmonary dysplasia (BPD), congenital lung abnormalities, interstitial lung diseases, chronic respiratory failure/insufficiency and neuromuscular respiratory diseases, including assistive therapies such as oxygen, mechanical ventilation, airway clearance devices, or an artificial airway.


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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. McGarry ME, Neuhaus JM, Nielson DW, Burchard E, Ly N. Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis. Pediatr Pulmonol. 2017 Oct 30. PMID: 29082671.
      View in: PubMed
    2. Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2017 Aug 30. PMID: 28866107.
      View in: PubMed
    3. Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN, et al. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 Feb 01; 195(3):302-313. PMID: 27556234.
      View in: PubMed
    4. DelRosso LM, Palacay P, Ly N. A 6-Month-Old Infant With Different Capnography Values in Polysomnography. Chest. 2017 Feb; 151(2):e45-e48. PMID: 28183504.
      View in: PubMed
    5. McGarry ME, Illek B, Ly NP, Zlock L, Olshansky S, Moreno C, Finkbeiner WE, Nielson DW. In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies. Pediatr Pulmonol. 2017 Apr; 52(4):472-479. PMID: 28068001.
      View in: PubMed
    6. DelRosso LM, Hoque R, Mitchell C, Ly NP. Severe Postictal Hypoxemia-Associated Seizure in a 12-Year-Old Child. J Clin Sleep Med. 2016 Dec 15; 12(12):1691-1693. PMID: 27655456.
      View in: PubMed
    7. Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 Dec; 138(6):1608-1618.e12. PMID: 27777180.
      View in: PubMed
    8. Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18; 375(7):619-30. PMID: 27532828.
      View in: PubMed
    9. DelRosso LM, Hoque R, Contreras MB, Ly NP. A 16-Year-Old Boy with Refractory Epilepsy and Sleep-Disordered Breathing. J Clin Sleep Med. 2016 Jul 15; 12(7):1062-4. PMID: 27092692; PMCID: PMC4918990 [Available on 01/15/17].
    10. Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CA, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17; 314(19):2034-2044. PMID: 26575060; PMCID: PMC4757487.
    11. Gibb E, Blount R, Lewis N, Nielson D, Church G, Jones K, Ly N. Management of plastic bronchitis with topical tissue-type plasminogen activator. Pediatrics. 2012 Aug; 130(2):e446-50. PMID: 22802609.
      View in: PubMed
    12. Lange NE, Celedón JC, Forno E, Ly NP, Onderdonk A, Bry L, Delaney ML, DuBois AM, Gold DR, Weiss ST, Litonjua AA. Maternal intestinal flora and wheeze in early childhood. Clin Exp Allergy. 2012 Jun; 42(6):901-8. PMID: 22909161; PMCID: PMC3428746.
    13. McLoughlin RM, Calatroni A, Visness CM, Wallace PK, Cruikshank WW, Tuzova M, Ly NP, Ruiz-Perez B, Kattan M, Bloomberg GR, Lederman H, Gern JE, Gold DR. Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort. Clin Exp Allergy. 2012 Mar; 42(3):392-404. PMID: 22092655; PMCID: PMC4162345.
    14. Ly NP, Litonjua A, Gold DR, Celedón JC. Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity? J Allergy Clin Immunol. 2011 May; 127(5):1087-94; quiz 1095-6. PMID: 21419479; PMCID: PMC3085575.
    15. Wu BH, Cabana MD, Hilton JF, Ly NP. Race and asthma control in the pediatric population of Hawaii. Pediatr Pulmonol. 2011 May; 46(5):442-51. PMID: 21194172.
      View in: PubMed
    16. Ly NP, Ruiz-Perez B, McLoughlin RM, Visness CM, Wallace PK, Cruikshank WW, Tzianabos AO, O'Connor GT, Gold DR, Gern JE. Characterization of regulatory T cells in urban newborns. Clin Mol Allergy. 2009 Jul 08; 7:8. PMID: 19586545; PMCID: PMC2717905.
    17. Hunninghake GM, Soto-Quirós ME, Lasky-Su J, Avila L, Ly NP, Liang C, Klanderman BJ, Raby BA, Gold DR, Weiss ST, Celedón JC. Dust mite exposure modifies the effect of functional IL10 polymorphisms on allergy and asthma exacerbations. J Allergy Clin Immunol. 2008 Jul; 122(1):93-8, 98.e1-5. PMID: 18440625.
      View in: PubMed
    18. Ly NP, Soto-Quirós ME, Avila L, Hunninghake GM, Raby BA, Laskey D, Sylvia JS, Celedón JC. Paternal asthma, mold exposure, and increased airway responsiveness among children with asthma in Costa Rica. Chest. 2008 Jan; 133(1):107-14. PMID: 17989151.
      View in: PubMed
    19. Ly NP, Celedón JC. Family history, environmental exposures in early life, and childhood asthma. J Allergy Clin Immunol. 2007 Aug; 120(2):271-2. PMID: 17666215.
      View in: PubMed
    20. Hunninghake GM, Soto-Quirós ME, Avila L, Su J, Murphy A, Demeo DL, Ly NP, Liang C, Sylvia JS, Klanderman BJ, Lange C, Raby BA, Silverman EK, Celedón JC. Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood. J Allergy Clin Immunol. 2007 Jul; 120(1):84-90. PMID: 17561245.
      View in: PubMed
    21. Hunninghake GM, Soto-Quiros ME, Avila L, Ly NP, Liang C, Sylvia JS, Klanderman BJ, Silverman EK, Celedón JC. Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica. J Allergy Clin Immunol. 2007 Mar; 119(3):654-61. PMID: 17336615.
      View in: PubMed
    22. Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR. Cord blood cytokines and acute lower respiratory illnesses in the first year of life. Pediatrics. 2007 Jan; 119(1):e171-8. PMID: 17145902; PMCID: PMC1994927.
    23. Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006 Oct; 84(4):903-11. PMID: 17023719; PMCID: PMC1994925.
    24. Ly NP, Ruiz-Pérez B, Onderdonk AB, Tzianabos AO, Litonjua AA, Liang C, Laskey D, Delaney ML, DuBois AM, Levy H, Gold DR, Ryan LM, Weiss ST, Celedón JC. Mode of delivery and cord blood cytokines: a birth cohort study. Clin Mol Allergy. 2006 Sep 26; 4:13. PMID: 17002791; PMCID: PMC1592116.
    25. Ly NP, Gold DR, Weiss ST, Celedón JC. Recurrent wheeze in early childhood and asthma among children at risk for atopy. Pediatrics. 2006 Jun; 117(6):e1132-8. PMID: 16740815.
      View in: PubMed
    26. Gold DR, Willwerth BM, Tantisira KG, Finn PW, Schaub B, Perkins DL, Tzianabos A, Ly NP, Schroeter C, Gibbons F, Campos H, Oken E, Gillman MW, Palmer LJ, Ryan LM, Weiss ST. Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma. J Allergy Clin Immunol. 2006 Apr; 117(4):931-8. PMID: 16630954; PMCID: PMC1508138.
    27. Ly NP, Komatsuzaki K, Fraser IP, Tseng AA, Prodhan P, Moore KJ, Kinane TB. Netrin-1 inhibits leukocyte migration in vitro and in vivo. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14729-34. PMID: 16203981; PMCID: PMC1253572.
    28. Ly NP, Li Y, Sredl DL, Perkins DL, Finn PW, Weiss ST, Gold DR. Elevated allergen-induced IL-13 secretion predicts IgE elevation in children ages 2-5 years. J Clin Immunol. 2005 Jul; 25(4):314-20. PMID: 16133987.
      View in: PubMed
    29. Dahl M, Hersh CP, Ly NP, Berkey CS, Silverman EK, Nordestgaard BG. The protease inhibitor PI*S allele and COPD: a meta-analysis. Eur Respir J. 2005 Jul; 26(1):67-76. PMID: 15994391.
      View in: PubMed
    30. Hersh CP, Dahl M, Ly NP, Berkey CS, Nordestgaard BG, Silverman EK. Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis. Thorax. 2004 Oct; 59(10):843-9. PMID: 15454649; PMCID: PMC1746834.
    31. Contreras JP, Ly NP, Gold DR, He H, Wand M, Weiss ST, Perkins DL, Platts-Mills TA, Finn PW. Allergen-induced cytokine production, atopic disease, IgE, and wheeze in children. J Allergy Clin Immunol. 2003 Dec; 112(6):1072-7. PMID: 14657861.
      View in: PubMed
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